Factors for modifying the termination of resuscitation rule in out-of-hospital cardiac arrest.

abstract：BACKGROUND:Compared with men, women have more evidence of myocardial ischemia with no obstructive coronary artery disease. Although low endogenous estrogen levels are associated with endothelial dysfunction, the role of low-dose hormone therapy has not been fully evaluated. We postulate that a 12-week duration of low-d...

journal_title：American heart journal

authors： Merz CN,Olson MB,McClure C,Yang YC,Symons J,Sopko G,Kelsey SF,Handberg E,Johnson BD,Cooper-DeHoff RM,Sharaf B,Rogers WJ,Pepine CJ

更新日期：2010-06-01 00:00:00

abstract：:Although many patients with coronary artery disease (CAD) have a positive exercise test without pain, the frequency and significance of this "silent" ischemia is unclear. Therefore, we studied 122 consecutive clinically stable patients with angiographically defined CAD (greater than 75 per cent luminal stenosis) and a...

journal_title：American heart journal

authors： Lindsey HE Jr,Cohn PF

更新日期：1978-04-01 00:00:00

abstract：:Major cardiovascular risk factors, such as hypertension, hyperlipidemia, and diabetes, often cluster in the same individuals. It has been claimed that obesity, hyperinsulinemia, insulin resistance, and a deranged intracellular handling of ions have pathogenetic importance in the development of this metabolic syndrome....

journal_title：American heart journal

authors： Lind L,Lithell H

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Despite the known benefits of cardiac rehabilitation in patients with coronary artery disease, referral rates to rehabilitation programs remain low. We determined the incidence and determinants of cardiac rehabilitation referral rates for patients undergoing percutaneous coronary intervention (PCI). METHODS...

journal_title：American heart journal

authors： Aragam KG,Moscucci M,Smith DE,Riba AL,Zainea M,Chambers JL,Share D,Gurm HS

更新日期：2011-03-01 00:00:00

abstract：:Valve area and cardiac output were determined with magnetic resonance (MR) velocity mapping in 12 patients with aortic stenosis. Heart catheterization, Doppler echocardiography, and indicator dilution were performed for comparison. Left ventricle could be catheterized in only nine patients; in these cases, MR measured...

journal_title：American heart journal

authors： Søndergaard L,Hildebrandt P,Lindvig K,Thomsen C,Ståhlberg F,Kassis E,Henriksen O

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Serum levels of pregnancy-associated plasma protein-A (PAPP-A) have recently been linked to plaque instability and are increased in acute coronary syndromes. The relation between PAPP-A levels and coronary risk factors, namely blood lipids, has not been studied to date. We have therefore investigated whether...

journal_title：American heart journal

authors： Stulc T,Malbohan I,Malík J,Fialová L,Soukupová J,Ceska R

更新日期：2003-12-01 00:00:00

abstract：:The presence and severity of functional mitral regurgitation were quantified by Doppler echocardiography in 17 patients with dilated cardiomyopathy and no evidence of primary valvular disease. Mitral regurgitant fraction was greater than 20% in 11 of the 17 patients, and exceeded 40% in four patients. Total stroke vol...

journal_title：American heart journal

authors： Keren G,Katz S,Strom J,Sonnenblick EH,LeJemtel TH

更新日期：1988-09-01 00:00:00

abstract：:Body surface isopotential maps were recorded in 30 normal subjects and 32 patients with clinical evidence of old anterior myocardial infarction but without ECG findings of infarction. Position of the minimum in maps was compared at 5 msec intervals from the onset of QRS between the normal and infarction groups. A sign...

journal_title：American heart journal

authors： Hirai M,Ohta T,Kinoshita A,Toyama J,Nagaya T,Yamada K

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Perflenapent injectable emulsion is a newer echocardiographic contrast agent that provides chamber opacification and improved endocardial border delineation. In >1000 patients tested, adverse effects have been minimal. However, previous studies have included few patients with congestive heart failure (CHF) o...

journal_title：American heart journal

authors： Kitzman DW,Wesley DJ

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:The American Heart Association recommends women with congenital heart defects (CHD) receive contraceptive counseling early in their reproductive years, but little is known about contraceptive method use among women with CHD. We describe recent female sterilization and reversible prescription contraceptive me...

journal_title：American heart journal

authors： Anderson KN,Tepper NK,Downing K,Ailes EC,Abarbanell G,Farr SL

更新日期：2020-04-01 00:00:00

abstract：:Adventitial heparin delivery has been shown to inhibit thrombosis and neointimal thickening in a rat carotid injury model. To determine whether sustained, local delivery of hirulog, a potent antithrombin agent, inhibits thrombus formation and neointimal thickening after arterial stenting, silicone polymers containing ...

journal_title：American heart journal

authors： Muller DW,Gordon D,Topol EJ,Levy RJ,Golomb G

更新日期：1996-02-01 00:00:00

abstract：:The single-dose pharmacokinetics of amiodarone have been studied in volunteer subjects given 400 mg doses by the intravenous and oral routes. The data show the compound to have a very large volume of distribution, a low total clearance, and a long and variable terminal elimination half-life. In patients the terminal e...

journal_title：American heart journal

authors： Holt DW,Tucker GT,Jackson PR,Storey GC

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Because coronary artery disease (CAD) is a prevalent comorbidity in patients with low ejection function (EF), a number of patients with heart failure undergo diagnostic cardiac catheterization. The objective of this study was to develop a model to assist clinicians in determining the likelihood of CAD before...

journal_title：American heart journal

authors： Whellan DJ,Tuttle RH,Velazquez EJ,Shaw LK,Jollis JG,Ellis W,O'Connor CM,Califf RM,Borges-Neto S

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Insulin, in addition to its known metabolic effects, has sympatho-excitatory and vasodilatory actions on muscular blood vessels. The goal of this study was to evaluate insulin sensitivity in young women with vasovagal syncope and positive tilt test results (HUT+) and to compare it with that in patients with ...

journal_title：American heart journal

authors： Ruiz GA,Calvar C,Hermes R,Rivadeneira D,Bengolea V,Chirife R,Tentori MC,Gelpi RJ

更新日期：2003-05-01 00:00:00

abstract：:Exercise stress testing is a well-established method for the diagnostic, prognostic, and functional assessment of patients with known or suspected CAD. A variety of alternative tests have been described in patients unable to perform leg exercise. Atrial pacing and dipyridamole imaging have been evaluated most extensiv...

journal_title：American heart journal

authors： Stratmann HG,Kennedy HL

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with an adverse prognosis in patients with coronary heart disease. Cardiac rehabilitation (CR) improves morbidity and mortality among patients with coronary heart disease, but its impact on patients with concomitant CKD has not been described. METHODS:We compared b...

journal_title：American heart journal

authors： Venkataraman R,Sanderson B,Bittner V

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Intracranial hemorrhage is an uncommon but very dangerous complication in patients receiving thrombolytic therapy for acute myocardial infarction. Neurosurgical evacuation is often an available treatment option. However, the association between neurosurgical evacuation and clinical outcomes in these patients...

journal_title：American heart journal

authors： Mahaffey KW,Granger CB,Sloan MA,Green CL,Gore JM,Weaver WD,White HD,Simoons ML,Barbash GI,Topol EJ,Califf RM

更新日期：1999-09-01 00:00:00

abstract：:The prognostic significance of functional status has not been previously studied in the setting of acute myocardial infarction. We assessed the Karnofsky Performance Status (KPS) score, a simple functional status scale that is commonly used to categorize physical ability, in 849 patients with acute myocardial infarcti...

journal_title：American heart journal

authors： Brezinski D,Stone PH,Muller JE,Tofler GH,Davis V,Parker C,Hartley LH,Braunwald E

更新日期：1991-05-01 00:00:00

abstract：:In this study, we reviewed M-mode and two-dimensional (2DE) echocardiographic observations in 13 patients with pulmonary atresia with ventricular septal defect and in six patients with truncus arteriosus in order to attempt to identify echocardiographic features distinguishing these two abnormalities in which no anato...

journal_title：American heart journal

authors： Vargas Barron J,Sahn DJ,Attie F,Valdes-Cruz LM,Grenadier E,Allen HD,Oliveira Lima C,Goldberg SJ

更新日期：1983-02-01 00:00:00

abstract：:Percutaneous coronary interventions have been performed for 20 years. Despite the success and progress of these interventions, abrupt vessel closure has been a dramatic adverse event of coronary interventions. Closure has frequently led to the major complications of death, myocardial infarction, and emergency coronary...

journal_title：American heart journal

authors： Bergelson BA,Fishman RF,Tommaso CL

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that thrombolysis is used less often in blacks than in whites. However, whether the greater prevalence of contraindications or less specific electrocardiographic manifestations of myocardial infarction (MI) account for this difference is unclear. METHODS AND RESULTS:We studie...

journal_title：American heart journal

authors： Manhapra A,Khaja F,Syed M,Rybicki BA,Wulbrecht N,Alam M,Sabbah H,Goldstein S,Borzak S

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Some pharmacist-managed anticoagulation services (PMAS) provide initial follow-up to patients on oral anticoagulant, who are transferred to their physician once they are stabilized. This may be as effective as and less expensive than long-term PMAS follow-up. METHODS:Once PMAS patients were stabilized and r...

journal_title：American heart journal

authors： Lalonde L,Martineau J,Blais N,Montigny M,Ginsberg J,Fournier M,Berbiche D,Vanier MC,Blais L,Perreault S,Rodrigues I

更新日期：2008-07-01 00:00:00

abstract：:Antiarrhythmic drugs are often more effective in suppressing ventricular tachycardias than are background premature extrasystoles. The mechanism of action of these agents was examined by studies on the effects of lidocaine and quinidine on post-repolarization refractoriness of both basic and premature action potential...

journal_title：American heart journal

authors： Nakaya Y,Nii H,Nomura M,Fujino K,Mori H

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Long-term treatment with beta-blockers reduces mortality after acute myocardial infarction (AMI). Whether beta-blockers exert a class effect is unknown. METHODS:We analyzed mortality after AMI in Canadian patients 65 years or older who were discharged from hospital with a diagnosis of AMI from April 1996 to...

journal_title：American heart journal

authors： Rinfret S,Abrahamowicz M,Tu J,Humphries K,Eisenberg MJ,Richard H,Austin PC,Pilote L

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Drug-eluting stents have been shown to reduce restenosis in many types of lesions. The purpose of this article is to assess the efficacy of sirolimus- and paclitaxel-eluting stents in patients with bifurcation lesions. METHODS:Between June 2003 and October 2004, 205 patients were enrolled in a prospective r...

journal_title：American heart journal

authors： Pan M,Suárez de Lezo J,Medina A,Romero M,Delgado A,Segura J,Ojeda S,Mazuelos F,Hernandez E,Melian F,Pavlovic D,Esteban F,Herrador J

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Pharmacodynamic studies reported an amplified on-clopidogrel platelet inhibition in smokers potentially caused by an increased metabolic drug activation via induction of cytochrome P450 1A2. The aims of this analysis were to evaluate the impact of smoking on the antiplatelet effect of clopidogrel and prasugr...

journal_title：American heart journal

authors： Hochholzer W,Trenk D,Mega JL,Morath T,Stratz C,Valina CM,O'Donoghue ML,Bernlochner I,Contant CF,Guo J,Sabatine MS,Schömig A,Neumann FJ,Kastrati A,Wiviott SD,Sibbing D

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Many young investigators are interested in cardiovascular (CV) outcomes research; however, the current training experience of early investigators across the United States is uncertain. METHODS:From April to November 2014, we surveyed mentees and mentors of early-stage CV outcomes investigators across the Un...

journal_title：American heart journal

authors： Khazanie P,Al-Khatib SM,Wang TY,Crowley MJ,Kressin NR,Krumholz HM,Kiefe CI,Wells BL,O'Brien SM,Peterson ED,Sanders GD

更新日期：2018-02-01 00:00:00

abstract：:The pharmacokinetic properties and hemodynamic effect of molsidomine and its pharmacologically active metabolite SIN-1 were investigated in 13 healthy volunteers following single oral doses. Hemodynamic changes were measured by finger plethysmography (peripheral arterial resistance), impedance plethysmography (venous ...

journal_title：American heart journal

authors： Meinertz T,Brandstätter A,Trenk D,Jähnchen E,Ostrowski J,Gärtner W

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:In recent reports, human toll-like receptor (TLR) 8 mediates the antiviral response by recognizing single-stranded RNA. The inflammatory response against enteroviral (EV) RNA replication may play an important role in dilated cardiomyopathy (DCM). The purpose of this study was to determine whether TLR8 was ex...

journal_title：American heart journal

authors： Satoh M,Akatsu T,Ishikawa Y,Minami Y,Takahashi Y,Nakamura M

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Glycoprotein (GP) IIb/IIIa inhibitors can improve outcomes in patients with non-ST-segment elevation acute coronary syndromes but raise the risk of bleeding, particularly if dosed in excess. The impact of GP IIb/IIIa dosing feedback on safety and major bleeding is unknown. METHODS:Glycoprotein IIb/IIIa dosi...

journal_title：American heart journal

authors： Mudrick DW,Chen AY,Roe MT,Newby LK,Gibler WB,Ohman EM,Peterson ED,Alexander KP

更新日期：2010-12-01 00:00:00