Amiodarone pharmacokinetics.

abstract：:The QRS complex and ST segment in the ECGs of 80 patients who died of an acute myocardial infarction (MI) were studied in relation to the extent of the MI (subendocardial vs. transmural). Changes in the QRS complex developed in nine out of the 15 cases with an acute subendocardial MI. Five of these cases fulfilled the...

journal_title：American heart journal

authors： Raunio H,Rissanen V,Romppanen T,Jokinen Y,Rehnberg S,Helin M,Pyörälä K

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Elevations of creatine kinase-MB (CK-MB) and cardiac troponin T (cTnT) have an uncertain long-term prognostic value after coronary artery bypass graft (CABG) surgery. We aimed to test the hypothesis that CK-MB and cTnT are predictors of long-term survival after CABG and to assess which of these 2 biomarkers ...

journal_title：American heart journal

authors： Søraas CL,Friis C,Engebretsen KV,Sandvik L,Kjeldsen SE,Tønnessen T

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Anginal chest pain without creatine kinase (CK) elevation is frequently observed in the first hours after coronary stenting. Possible causes of ischemic episodes are microembolism, side branch occlusion, coronary vasospasm, and disturbances of microvascular circulation. In a prospective, double-blind, random...

journal_title：American heart journal

authors： Kurz DJ,Naegeli B,Bertel O

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Adenosine cardiac stress is widely used as an alternative to exercise testing during myocardial perfusion imaging (MPI). Dyspnea often accompanies the adenosine stress test. Although known asthmatic patients are excluded from this test because of the danger of bronchospasm, there is incomplete information re...

journal_title：American heart journal

authors： Balan KK,Critchley M

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:We investigated the presence of left ventricular hypertrophy (LVH) and features of diastolic dysfunction in genotype-confirmed children from families with hypertrophic cardiomyopathy (HCM) and healthy control children. BACKGROUND:In subjects with HCM-causing mutations, LVH usually does not evolve until adol...

journal_title：American heart journal

authors： Poutanen T,Tikanoja T,Jääskeläinen P,Jokinen E,Silvast A,Laakso M,Kuusisto J

更新日期：2006-03-01 00:00:00

abstract：:Mitochondria in skeletal and cardiac muscle have been found to be less stable in aging hamsters, in contrast to preparations from young animals. We have found previously that clofibrate (Atromid-S) will reverse this degeneration in the older hamsters. This study examined the exercise tolerance of aged hamsters, to see...

journal_title：American heart journal

authors： Guntheroth WG,Inamdar AR,Person R,Mackler B

更新日期：1977-10-01 00:00:00

abstract：:Automatic external defibrillators (AEDs) represent an important technologic innovation in the management of out-of-hospital cardiac arrest. We propose the following concept: AEDs are machines with the limited task of ventricular fibrillation (VF) identification, countershock delivery, and defibrillation. They cannot b...

journal_title：American heart journal

authors： Cummins RO,Eisenberg MS,Hallstrom AP,Hearne TR,Graves JR,Litwin PE

更新日期：1985-12-01 00:00:00

abstract：:Percutaneous transluminal coronary angioplasty (PTCA) was performed in 110 consecutive patients (111 vessels) with chronically occluded coronary arteries and was successful in 69 patients (69 vessels). Successful initial PTCA was related to the extent of coronary artery disease, the morphology of the proximal surface ...

journal_title：American heart journal

authors： Ishizaka N,Issiki T,Saeki F,Ishizaka Y,Ikari Y,Abe J,Soumitsu Y,Hashimoto H,Masaki K,Yamaguchi T

更新日期：1994-01-01 00:00:00

abstract：:Chronic exposure to fine particulate matter (PM2.5) is accepted as a causal risk factor for coronary heart disease (CHD). However, most of the evidence for this hypothesis is based upon cohort studies in whites, comprised of either only males or females who live in urban areas. It is possible that many estimates of th...

journal_title：American heart journal

authors： Loop MS,McClure LA,Levitan EB,Al-Hamdan MZ,Crosson WL,Safford MM

更新日期：2018-03-01 00:00:00

abstract：:Although cardiovascular disease remains the leading cause of death in the United States, cardiovascular disease mortality has decreased steadily during the past 2 decades. This trend is largely attributable to improved detection and management of cardiovascular risk factors, in which the Framingham Heart Study has pla...

journal_title：American heart journal

authors： Levy D,Wilson PW,Anderson KM,Castelli WP

更新日期：1990-03-01 00:00:00

abstract：:The presence and severity of functional mitral regurgitation were quantified by Doppler echocardiography in 17 patients with dilated cardiomyopathy and no evidence of primary valvular disease. Mitral regurgitant fraction was greater than 20% in 11 of the 17 patients, and exceeded 40% in four patients. Total stroke vol...

journal_title：American heart journal

authors： Keren G,Katz S,Strom J,Sonnenblick EH,LeJemtel TH

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:Previous studies reported an impairment of nervous autonomic activity in patients with Duchenne muscular dystrophy (DMD). However, the relationship of the autonomic dysfunction to the impairment of cardiac mechanical function and of respiratory failure is not completely understood. METHODS:We evaluated card...

journal_title：American heart journal

authors： Lanza GA,Dello Russo A,Giglio V,De Luca L,Messano L,Santini C,Ricci E,Damiani A,Fumagalli G,De Martino G,Mangiola F,Bellocci F

更新日期：2001-05-01 00:00:00

abstract：:Plasma levels of endothelin-1 are elevated in patients with chronic heart failure; however, it is unknown whether changes in plasma endothelin-1 levels accurately reflect clinical response to therapy in these patients. To determine this, we measured plasma endothelin-1 in addition to functional, hemodynamic, and other...

journal_title：American heart journal

authors： Krum H,Gu A,Wilshire-Clement M,Sackner-Bernstein J,Goldsmith R,Medina N,Yushak M,Miller M,Packer M

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Although sex differences exist in the management of acute coronary syndromes, less is known about the management and outcomes of women and men with suspected coronary artery disease being evaluated with noninvasive testing (NIT). METHODS:We investigated sex-based differences in NIT results and subsequent cl...

journal_title：American heart journal

authors： Pagidipati NJ,Coles A,Hemal K,Lee KL,Dolor RJ,Pellikka PA,Mark DB,Patel MR,Litwin SE,Daubert MA,Shah SH,Hoffmann U,Douglas PS,PROMISE Investigators.

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) experience poor outcomes after acute myocardial infarction (AMI). We sought to compare clinical characteristics of advanced CKD, dialysis, and non-CKD patients hospitalized with AMI. METHODS:This observational study used record-linked data from the US Renal Data Sy...

journal_title：American heart journal

authors： Shroff GR,Frederick PD,Herzog CA

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:We assessed left atrial function in normal subjects and in patients with hypertrophic cardiomyopathy (HCM) by using Doppler echocardiography at the supine position and after sudden standing. METHODS AND RESULTS:Twenty-seven patients with hypertrophic obstructive cardiomyopathy (HOCM), 17 patients with HCM, ...

journal_title：American heart journal

authors： Dernellis J,Tsiamis E,Stefanadis C,Pitsavos C,Toutouzas P

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Serum levels of pregnancy-associated plasma protein-A (PAPP-A) have recently been linked to plaque instability and are increased in acute coronary syndromes. The relation between PAPP-A levels and coronary risk factors, namely blood lipids, has not been studied to date. We have therefore investigated whether...

journal_title：American heart journal

authors： Stulc T,Malbohan I,Malík J,Fialová L,Soukupová J,Ceska R

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Statins are effective in the prevention of coronary events and the treatment of acute coronary syndromes. However, their efficacy and safety in patients with heart failure (HF) are unknown. In this review, we discuss the evidence for the efficacy and safety of statin therapy in patients with HF. METHODS:We ...

journal_title：American heart journal

authors： Raina A,Pickering T,Shimbo D

更新日期：2006-07-01 00:00:00

abstract：:The appearance of perivalvular cavities (PCs) in patients with infectious endocarditis (IE) was studied by transesophageal echocardiography (TEE) color Doppler examinations to determine whether the color Doppler TEE presentation was in keeping with the current concept of PCs representing abscesses. Two heart centers p...

journal_title：American heart journal

authors： Tingleff J,Egeblad H,Gøtzsche CO,Baandrup U,Kristensen BO,Pilegaard H,Pettersson G

更新日期：1995-07-01 00:00:00

abstract：:To estimate the incidence of residual atrial septal perforation (ASP) following percutaneous transvenous mitral commissurotomy (PTMC) with the Inoue balloon catheter and to examine the factors contributing to ASP, we studied 46 patients with mitral stenosis undergoing PTMC. Residual ASP was evaluated by Doppler color ...

journal_title：American heart journal

authors： Ishikura F,Nagata S,Yasuda S,Yamashita N,Miyatake K

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to estimate the cost-effectiveness of beta-blocker therapy with either metoprolol or carvedilol in addition to conventional therapy for patients with heart failure (HF) in Canada. DESIGN:A Markov simulation was used to estimate the costs and life expectancy for treating patients...

journal_title：American heart journal

authors： Levy AR,Briggs AH,Demers C,O'Brien BJ

更新日期：2001-09-01 00:00:00

abstract：:To assess relative capabilities of magnetic resonance (MR) imaging and two-dimensional echocardiography (2DE) for evaluating regional contractile dysfunction in the left ventricle after a myocardial infarction, results from 22 concurrent MR (orthogonal-transaxial, ECG-gated, multiphasic, single-spin echo) and 2DE exam...

journal_title：American heart journal

authors： White RD,Cassidy MM,Cheitlin MD,Emilson B,Ports TA,Lim AD,Botvinick EH,Schiller NB,Higgins CB

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:The risk for reinfarctions and delays in reperfusion after streptokinase therapy may be caused by the antifibrinolytic effect of platelet-derived type 1 plasminogen activator inhibitor (PAI-1). This study aims to show the relation of pretreatment PAI-1 levels of patients with acute myocardial infarction trea...

journal_title：American heart journal

authors： Sinkovic A

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:To define the incidence and cumulative risk of atrial fibrillation (AF) in a population-based cohort of whites and African Americans. BACKGROUND:African-Americans reportedly have a lower risk of AF than whites despite their higher exposure to AF risk factors. However, precise estimates of AF incidence in Af...

journal_title：American heart journal

authors： Alonso A,Agarwal SK,Soliman EZ,Ambrose M,Chamberlain AM,Prineas RJ,Folsom AR

更新日期：2009-07-01 00:00:00

abstract：:Pulmonary function was measured serially in two separate randomized trials of pindolol in the treatment of essential hypertension. Patients with overt obstructive airways disease were excluded. In study 1, 131 hypertensive patients were randomized to placebo (31) and 15 mg (33), 30 mg (33), and 60 mg (34) of pindolol....

journal_title：American heart journal

authors： Hamilton BP,Hamilton J,Kirkendall WM

更新日期：1982-08-01 00:00:00

abstract：:Fourteen fetuses with atrioventricular canal malformations were examined by two-dimensional echocardiography, pulsed-wave Doppler echocardiography, and color Doppler flow mapping. Eleven fetuses had complete and three fetuses had partial atrioventricular canal malformations. Nonimmune hydrops fetalis was associated wi...

journal_title：American heart journal

authors： Gembruch U,Knöpfle G,Chatterjee M,Bald R,Redel DA,Födisch HJ,Hansmann M

更新日期：1991-05-01 00:00:00

abstract：:In subjects without coronary disease, coronary perfusion pressure generated with closed-chest cardiopulmonary resuscitation (CPR) bears a direct relationship to myocardial blood flow. The effect of coronary lesions on this relationship was studied in an experimental porcine model not requiring thoracotomy. Coronary st...

journal_title：American heart journal

authors： Kern KB,Lancaster L,Goldman S,Ewy GA

更新日期：1990-08-01 00:00:00

abstract：:An extremely athletic 56-year-old male physician was found to have profound sinus bradycardia. His only symptom was markedly increased alertness while actively exercising. During pacemaker insertion he had an episode of prolonged sinus arrest terminated by a precordial thump. This case suggests that exercise can alter...

journal_title：American heart journal

authors： Marmor BM,Black MM

更新日期：1980-07-01 00:00:00

abstract：:Left ventricular ejection fraction and regional wall motion were assessed by multigated equilibrium radionuclide ventriculography within 24 hours of onset of first acute transmural myocardial infarction (MI) in 32 patients. Abnormal left ventricular wall motion was noted in all 16 patients with anterior infarction and...

journal_title：American heart journal

authors： Pichler M,Shah PK,Peter T,Singh B,Berman D,Shellock F,Swan HJ

更新日期：1983-11-01 00:00:00

abstract：:We studied the effect of propranolol administration on risk assessment based on submaximal exercise testing performed early after myocardial infarction. A total of 70 patients with recent infarction underwent modified Bruce treadmill testing with simultaneous measurement of expired gases in the absence of antianginal ...

journal_title：American heart journal

authors： Curtis JL,Houghton JL,Patterson JH,Koch G,Bradley DA,Adams KF Jr

更新日期：1991-06-01 00:00:00