[Treatment of Hodgkin's disease. National Protocol of Antineoplastic Drugs: preliminary report].

Abstract:

:We report preliminary results of treatment of Hodgkin disease according to the National Protocol on Antineoplastic Drugs. 37 males and 22 females with a median age of 34 years (range 16 to 76) were treated. Patients with stages I or II received radiotherapy alone or chemotherapy (C-MOPP) followed by radiotherapy. Patients with stages III or IV received radiotherapy and chemotherapy or alternating courses of C-MOPP and ABVD. Complete remission was observed in 74% of 39 patients completing full therapy. Complete remission was more common in patients with nodular sclerosis without B symptoms and under 45 years of age. Actuarial survival at 22 months was 79%, significantly higher for patients with nodular sclerosis compared to patients with lymphocytic depletion. Different treatments in patients at stages I and II or III and IV gave comparable results. Complications included infection with the Chickenpox-Zoster virus, pneumonia and fever of unknown origin. Mortality was associated to older age, complications of treatment or failure to comply with therapy.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Gutiérrez J,Osorio G,García H,Vacarezza R,Cao C

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

11-21

issue

1

eissn

0034-9887

issn

0717-6163

journal_volume

119

pub_type

杂志文章
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    abstract::Regardless of the diagnostic criteria, the metabolic syndrome is found at least in 20% of the population. The adipose tissue plays an important role in the insulin resistance found in this syndrome. Free fatty acids released by intra-abdominal adipocytes produce an inflammatory and pro-thrombotic response and the pers...

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    doi:/S0034-98872009000500014

    authors: Martínez R G,Alonso K R,Novik A V

    更新日期:2009-05-01 00:00:00

  • Morbid obesity in an adolescent with Prader-Willi syndrome.

    abstract::Prader-Willi syndrome is an uncommon multisystem genetic disorder caused by defects of chromosome 15 (15qll-ql3), often due to deletions or uniparental disomy The syndrome is characterized by neonatal hypotonia, dysmorphic facial features, short stature, motor and mental disabilities, behavioral changes, hyperphagia, ...

    journal_title:Revista medica de Chile

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    doi:/S0034-98872009000200012

    authors: Santos VM,Henrique de Paula F,Osterne EM,Nery NS,Turra TZ

    更新日期:2009-02-01 00:00:00

  • [Hepatitis B virus vaccine: early and late response in Chileans with high risk of infection].

    abstract:BACKGROUND:Hepatitis B vaccine has demonstrated to be very effective and safe preventing hepatitis B virus infection. Long term protection induced by hepatitis B vaccination depends on the initial immune response and the declining rate of anti-HBs titers. AIM. To investigate early and late response to hepatitis B vacci...

    journal_title:Revista medica de Chile

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    doi:

    authors: Hurtado C,Brahm J,Chesta J,Latorre R,Velasco M

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  • [Detection of neuroendocrine tumors by positron emission tomography-computed tomography with 68Ga-DOTATATE: report of one case].

    abstract::We report a 74-year-old male with liver metastases from a neuroendocrine tumor (NET) of unknown origin. Conventional imaging studies with ultrasound, computed tomography colonoscopy and Positron emission tomography-computed tomography (PET/CT) with 18Fluor odeoxyglucose did not identify the site of origin of the prima...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872009000400012

    authors: Amaral H,Pruzzo R,Redondo F,Gil MC,Pizarro A,de la Fuente H,Butte JM,Coudeu TM

    更新日期:2009-04-01 00:00:00

  • [Active and refractory ulcerative proctitis: an update].

    abstract::Ulcerative colitis (UC) is a chronic inflammatory disease of unknown etiology that affects a variable length of the colon, starting from the rectum. When the disease is confined to the rectum is called ulcerative proctitis (UP). Several studies have unsuccessfully attempted to determine the factors that determine the ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:/S0034-98872010000100016

    authors: Caselli M G,Pinedo M G,Zúñiga D A,Alvarez L M

    更新日期:2010-01-01 00:00:00

  • [Primary adrenal insufficiency due to autoimmune adrenalitis].

    abstract::We report a 10 years old boy, admitted with a history of asthenia, anorexia and weight loss of 4 kg. Initial laboratory work up showed metabolic acidosis and hyponatremia. The patient had no circadian rhythm of serum cortisol and an adrenal stimulation test confirmed the presence of adrenal insufficiency. Anti-adrenal...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Muzzo S,Izquierdo G,Verbeke S

    更新日期:2002-08-01 00:00:00

  • [Transition to adulthood of adolescents with inflammatory bowel disease].

    abstract::Inflammatory bowel disease (IBD) is a prevalent chronic disorder, often diagnosed during childhood. Studies have suggested that the incidence of IBD in this group of patients is increasing. Children and adolescents with IBD frequently have more extensive and severe disease than adults. Transition is an important conce...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872015000600010

    authors: Navarro E,Ossa JC,Simian D,Quera R

    更新日期:2015-06-01 00:00:00

  • [Cardiovascular risk factors in middle-age women with acute coronary syndromes].

    abstract:BACKGROUND:In Chile, 40% of deaths due to acute myocardial infarction occur in women. AIM:To assess the presence of cardiovascular risk factors in women with acute coronary syndromes. PATIENTS AND METHODS:Thirty four women aged 46 to 55 years old, admitted to the hospital due to an acute coronary syndrome and 102 age...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Blümel JE,Prieto JC,Leal T,Cruz MN,Gallardo L

    更新日期:2001-09-01 00:00:00

  • [Focal autoimmune pancreatitis versus pancreatic cancer: value of steroid treatment in the diagnosis].

    abstract:BACKGROUND:The differential diagnosis of pancreatic cancer and focal forms of autoimmune pancreatitis is complicated since serological tests, IgG4 and CA 19-9 have a low sensibility and specificity. CT scan and magnetic resonance imaging provide clear differentiation in the majority, but not in all cases. Endosonograph...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014000400001

    authors: Berger Z

    更新日期:2014-04-01 00:00:00

  • [Cerebral vasodilators].

    abstract::Cerebral vasodilators (CVD) account for 1.6% of the annual expenditure on drugs in Chile. Two kinds are typified: what we have called orthodox CVD and calcium-channel blockers. They have two main uses in neurology: firstly, in acute ischaemic stroke where orthodox CVD (buflomedil, codergocrine mesylate, and nicergolin...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Alvarez G,Vacarezza R

    更新日期:1990-07-01 00:00:00

  • [Wolff-Parkinson-White syndrome: late results of surgical treatment].

    abstract::We followed 25 patients operated on for Wolff-Parkinson-White syndrome between August 1985 and October 1989. Their mean age was 37 +/- 12 years and arrhythmia had been present for 5 to 30 years. A mean of 3.3 +/- 1.2 antiarrhythmic agents had failed in controlling recurrences. Tachycardia was orthodromic in 21 patient...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: González R,Morán S,Fajuri A,Irarrazabal MJ,Maturana G,Urzua J,Lema G,Espinoza R,Casanegra P

    更新日期:1990-08-01 00:00:00

  • [On the death of Gabriel Cano de Aponte].

    abstract::Gabriel Cano de Aponte was Governor of Chile since 1717 and until his death in 1733, being 68 years old. As a soldier, he was an experienced horse rider. The sequence of events that caused his death three months after an equestrian accident is unclear. A systematic clinical analysis of the latter is the main objective...

    journal_title:Revista medica de Chile

    pub_type: 传,历史文章,杂志文章

    doi:/S0034-98872008000900020

    authors: Bravo G S,Moles P P,Quiroga M D,Pancorvo P R,Espinoza G R

    更新日期:2008-09-01 00:00:00

  • [Early determinants of acute kidney injury during experimental intra-abdominal sepsis].

    abstract:BACKGROUND:Sepsis-induced acute kidney injury (AKI) is an early and frequent organ dysfunction, associated with increased mortality. AIM:To evaluate the impact of macrohemodynamic and microcirculatory changes on renal function and histology during an experimental model of intra-abdominal sepsis. MATERIAL AND METHODS:...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014000500001

    authors: Regueira T,Andresen M,Mercado M,Lillo F,Soto D

    更新日期:2014-05-01 00:00:00

  • [Idiopathic recurrent ventricular tachycardia: role of verapamil in its treatment].

    abstract::Verapamil is a calcium channel blocker ideally suited for the treatment of A-V nodal reciprocating supraventricular tachycardia. Most types of ventricular tachycardia are refractory to treatment with verapamil since they depend on sodium channels. However, a few cases of recurrent ventricular tachycardia are refractor...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: González R,Fajuri A,Arriagada C,Marchesse M,Serrat H

    更新日期:1989-04-01 00:00:00

  • [About the death of Herod the Great].

    abstract::Herod the Great was the founder of a dynasty that reigned on Judea for several generations. His birth date is estimated on year 73 AC and died at 70 years old. Descriptions of the final disease of Herod were obtained from the classical chronicles of Flavius Josephus, "The Jewish war" and "Jewish Antiquities". A medica...

    journal_title:Revista medica de Chile

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Espinoza R,Sepúlveda C,Vukusich C,Fantuzzi A,Serrano M,Simian M

    更新日期:2003-05-01 00:00:00

  • [Rhomboencephalitis caused by Listeria monocytogenes: a case studies with magnetic nuclear resonance].

    abstract::Central nervous system infections due to Listeria monocytogenes result in a variety of clinical syndromes ranging from meningitis to rhomboencephalitis. We report the case of a previously healthy patient with rhomboencephalitis in whom the CT scan was normal, while magnetic resonance imaging (MRI) confirmed the diagno...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Yulis J,Geny C,Levy R

    更新日期:1991-12-01 00:00:00

  • [Spontaneous tendon rupture in disseminated lupus erythematosus. A clinical case].

    abstract::A 37-year-old female with systemic lupus erythematosus and chronic treatment with steroids developed spontaneous bilateral rupture of tendons of both quadriceps muscles below the patella. Surgical treatment was undertaken with good results. The histologic features and a review of the literature are included. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Segovia A,Román JC,Hinojosa M,Ruiz A,Guzmán L

    更新日期:1990-09-01 00:00:00

  • [Addisonian crisis caused by metastatic lung cancer. Report of one case].

    abstract::Addisonian crisis as a first manifestation of metastatic disease secondary to cancer is uncommon. We report a 63-year-old man with a history of one year of fatigue, weakness, weight loss and repeated symptomatic hypoglycemia. The cortisol stimulation test with ACTH confirmed primary adrenal insufficiency. While receiv...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872011000900013

    authors: Utreras C,Díaz RE,Ascui R,Caro R,Véliz J,Wohllk N

    更新日期:2011-09-01 00:00:00

  • [Medical care costs for HIV-positive and AIDS patients in four hospitals in Santiago, Chile].

    abstract:BACKGROUND:Medical care of HIV infected and AIDS patients may represent an important economical burden for public hospitals. AIM:To assess direct and indirect costs of medical care for HIV infected and AIDS patients in public hospitals of the Metropolitan Region of Chile. MATERIAL AND METHODS:Between August 1994 and ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Toro L,Jara C,Adauy A,Henríquez A,Trujillo F,Child R,Ortiz E

    更新日期:1998-02-01 00:00:00

  • [Renal failure secondary to effort rhabdomyolysis: report of three cases].

    abstract::Renal failure secondary to effort rhabdomyolysis is uncommon. We report three males age 28, 37 (military sportsmen) and 44 years (sedentary obese), with this condition. Episodes occurred after a training session to run a triathlon, during the course of a mini marathon and during a rescue attempt of a drowning person. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872006000200012

    authors: Vega J,Gutiérrez M,Goecke H,Idiáquez J

    更新日期:2006-02-01 00:00:00

  • [Proposal to address the mental health problems detected after the February 27, 2010 earthquake].

    abstract::One of the most important topics mentioned by people from places affected by the February 27th, 2010 earthquake to the Presidential Delegation for the Reconstruction, was the urgent need of mental health care. Given the enormous individual and social burden of mental health sequelae after disasters, its treatment beco...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872016000200014

    authors: Figueroa RA,Cortés PF

    更新日期:2016-02-01 00:00:00

  • [Origin and development of the book Medical Semiology].

    abstract::Semiotics and Semiology share a similar etymology and meaning: the study of signs. In Medicine, signs are objective manifestations of disease, as opposed to the subjective nature of symptoms. Medical semiology comprises the study of symptoms, somatic signs and laboratory signs, history taking and physical examination ...

    journal_title:Revista medica de Chile

    pub_type: 历史文章,杂志文章

    doi:10.4067/s0034-98872018000300387

    authors: Goic G A

    更新日期:2018-03-01 00:00:00

  • [Prepatency, parasitemia and histological lesions in mice infected with two Trypanosoma cruzi populations isolated in Chile].

    abstract:BACKGROUND:The great variability in the clinical presentation of Chagas disease may depend in part in the genetic variability of Trypanosoma cruzi populations. AIM:To compare prepatent period, parasitemia, mortality and histological lesions in mice infected with two populations of Trypanosoma cruzi isolated in Chile. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872005000400006

    authors: Pizzi P T,Wallace R A,Villagra O R,Muñoz V S,Ortiz Z S,Solari I A

    更新日期:2005-04-01 00:00:00

  • [Classic and molecular methodologies for the identification of Enterococcus species].

    abstract:BACKGROUND:Enterococcus is a bacterial genus with low virulence. However, in the last years, the importance of some enterococcus species as nosocomial pathogens has increased, specially due to their resistance to some antimicrobial. AIM:To identify enterococcus strains using classical biochemical techniques and genomi...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Sepúlveda M,Bello H,Ruiz M,Hormazábal J,Domínguez M,González G,Mella S,Zemelman R

    更新日期:2002-01-01 00:00:00

  • [Effects of ursodeoxycholic acid in patients with cholestasis of pregnancy].

    abstract::In an open, pilot study, the efficacy and safety of ursodeoxycholic acid (UDCA) in the treatment of intrahepatic cholestasis of pregnancy was investigated. Four patients received 1 g/day of UDCA during 20 days and another 2 patients received 2 identical periods of treatment separated by a 14-day interval free of drug....

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Palma J,Reyes H,Ribalta J,Iglesias J,González M,Hernández I,Alvarez C,Molina C,Danitz AM

    更新日期:1991-02-01 00:00:00

  • [Metabolic control of non insulin dependent diabetes mellitus in surgery].

    abstract::We followed 50 type II diabetic patients undergoing various types of surgical procedures. Control of blood sugar was evaluated as percent of tests within an acceptable limit defined as 160 mg/dl in the preoperative period, 80-240 mg/dl in the early postoperative period and 80-120 mg/dl thereafter. Adequate control was...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Morales H,Maiz A,Arteaga A

    更新日期:1989-07-01 00:00:00

  • [Use of intravenous immunoglobulin for the treatment of toxic epidermal necrolysis and Stevens-Johnson/toxic epidermal necrolysis overlap syndrome. Review of 15 cases].

    abstract:BACKGROUND:Toxic epidemial necrolysis (TEN) is an acute adverse drug reaction, that has an unpredictableprogression and a 30% mortality. The incidence of TEN in the general population is approximately 0.4 to 1.2 cases/million/year. It is characterized pathologically by keratinocyte apoptosis which leads to epidemial de...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872009000300009

    authors: Molgó M,Carreño N,Hoyos-Bachiloglu R,Andresen M,González S

    更新日期:2009-03-01 00:00:00

  • [Subcorneal pustular dermatosis: report of one case].

    abstract:BACKGROUND:We report a 35-year-old female patient with a one year history of a pustular and painful erythematous dermatitis, located in great folds, pubis and abdomen. She was evaluated in primary health care, receiving antifungal treatment, antimicrobials, topical and systemic non-steroidal anti-inflammatory drugs, wi...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872012000500012

    authors: Valenzuela Y,Ramírez C,Bellolio E

    更新日期:2012-05-01 00:00:00

  • [Day care attendance: impact on acute lower respiratory disease in children under 2 years old].

    abstract:AIM:To measure the impact of day care attendance on lower respiratory tract infections in children under two years old in two urban settings with different degrees of air pollution. SUBJECTS AND METHODS:A 26 week follow up, during fall and winter of 1991 and 1992, was performed to 98 children (48 attending day care an...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Vargas Catalán NA,Díaz Amor P,Zuleta Quiroz A,López Bravo IM,Venegas Silva V

    更新日期:1994-07-01 00:00:00

  • [Contribution of iron of bread to the Chilean diet].

    abstract::The content and bioavailability of iron contained in Chilean bread was studied in a random sample from 301 bakeries. A wet digestion procedure followed by a colorimetric method was used. Iron bioavailability was examined in 9 adult women using the extrinsic radioactive tag method. The iron content of bread was 2.4 +/-...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Peña G,Pizarro F,Hertrampf E

    更新日期:1991-07-01 00:00:00