Abstract:
BACKGROUND:Hepatitis B vaccine has demonstrated to be very effective and safe preventing hepatitis B virus infection. Long term protection induced by hepatitis B vaccination depends on the initial immune response and the declining rate of anti-HBs titers. AIM. To investigate early and late response to hepatitis B vaccine in a sample of high risk Chilean population. MATERIAL AND METHODS:Thirty one subjects (20 relatives of hepatitis B chronic carriers, 10 health service workers and one HIV seropositive) were vaccinated with a plasma derivated hepatitis B vaccine. Early and late response were estimated by anti-HBs titers. RESULTS:Twenty eight subjects (90%) produced protective titers of anti-HBs after 2 months from the third dose of vaccine (early response), and they remained at these levels in 75% of vaccinated individuals after three years (late response). All the subjects without protective titers after the three year follow up had produced anti-HBs levels lower than 300 UI at the early response. Hepatitis B vaccination was not associated with significant side effects. CONCLUSIONS:This experience confirms that hepatitis B vaccine is safe and effective inducing immunity in high risk subjects. Our data suggest that the early response to hepatitis B vaccine is able to identify those subjects requiring closer surveillance for boosters.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Hurtado C,Brahm J,Chesta J,Latorre R,Velasco Msubject
Has Abstractpub_date
1993-05-01 00:00:00pages
503-5issue
5eissn
0034-9887issn
0717-6163journal_volume
121pub_type
杂志文章abstract:BACKGROUND:Type 2 diabetes etiology has a strong genetic component. More than 20 genetic variants have been associated with diabetes and other metabolic markers. However, the polymorphism rs7903146 of the TCF7L2 gene has shown the strongest association. AIM:To investigate the association of TCF7L2 (rs7903146) genotype...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000800965
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Osteoporotic hip fractures are devastating events in older women. There is a genetic modulation of bone phenotypic parameters including bone density (BMD) and bone fragility fractures. Vitamin D receptor (VDR) gene polymorphisms explain a small part of the genetic influence on BMD, whereas their effect on fr...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008000400008
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Felodipine is a calcium channel inhibitor with high vascular selectivity. AIM:To study the effectiveness of felodipine in the treatment of essential hypertension in subjects older than 64 years old. PATIENTS AND OUTCOME:Fifty subjects were studied. After a washout period of four weeks, subjects received a ...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Recent studies have described a high percentage of small intestinal bacterial overgrowth (SIBO) in patients with irritable bowel syndrome (IBS). However, the prevalence of SIBO has not been well established in other functional disorders. AIM:To evaluate the prevalence of SIBO in patients with different func...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872007001000003
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Skin prick test (SPT) of immediate hypersensitivity is a main instrument in the diagnosis of allergy. AIM:To demonstrate the applicability of skin prick test in different age groups. PATIENTS AND METHODS:We studied children and adolescents with the diagnosis of allergy in the Pediatric Respiratory Laborato...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872005000200007
更新日期:2005-02-01 00:00:00
abstract::Medical specialization has brought about the need to guarantee suitability for its practice. The progressive changes in knowledge and the incorporation of specific technologies, set forth the need to periodically demonstrate this capacity. In developed countries different initiatives, that sooner or later will become ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND:Soft tissue foreign bodies are a frequent cause of consultation in emergency rooms. It is difficult to verify their existence since conventional radiology only detects radio opaque objects. Ultrasound can be a useful diagnostic procedure. AIM:To report our experience in the detection of soft tissue foreign ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract::Gallbladder carcinoma is frequent in Chile. The aim of this study was to report the mutagenicity of whole human bile, using the Ames/Salmonella microsome assay with Salmonella typhimurium TA98. The bile of 19 patients, aged 23 to 64 years old, subjected to cholecystectomy was examined, and mutagen activity was found i...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract::Beta 2 microglobulin is a low molecular weight protein integrating the light chain HLA antigens. Its serum concentration is increased in different neoplasias and in renal failure. Using solid phase RIA we determined the concentration of beta 2 microglobulin in plasma and spinal fluid of 57 healthy individuals and pati...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract::Platelet Rich Plasma (PRP) is used in musculoskeletal lesion surgery, including muscle, bone, tendons and ligaments. PRP might accelerate the healing process and the integration of the graft, allowing an earlier return to sports activities of patients. PRP is obtained from autologous blood, which is centrifuged, obtai...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872013001000011
更新日期:2013-10-01 00:00:00
abstract::In our country, acute cecal volvulus is responsible of 3.3% of mechanical large bowel obstructions. More than half of these cases have a history compatible with intermittent cecal volvulus, an usually overlooked diagnosis. The author reports two cases of intermittent cecal volvulus, treated in the last ten years. Both...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract::We studied 36 men and 94 women aged 60 to 85 years, without nutritional deficiencies or illness that could interfere with hematopoiesis, to characterize the normal limits of red and white blood cell counts. Lower limit of hemoglobin normal values were 132 g/l for men and 125 g/l for women. The corresponding figures fo...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Subjects with glucose intolerance or high fasting glucose levels have a higher cardiovascular risk and frequently become diabetic. AIM:To assess clinical and metabolic characteristics of patients with glucose intolerance or high fasting glucose levels. MATERIAL AND METHODS:Fasting and post glucose load ser...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009000200002
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Cardiac rehabilitation (CR) programs play an important role in the control and prevention of new cardiac events. AIM:A survey was performed to evaluate the current situation of CR programs in Chile. MATERIAL AND METHODS:A questionnaire evaluating the structure of rehabilitation centers, characteristics of ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000500002
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Valsartan is an angiotensin AT1 receptor antagonist. Clinical studies have shown that this is an effective and well tolerated drug. AIM:To compare valsartan with other commonly used antihypertensives in a National multicentric study. MATERIAL AND METHODS:Between 1997 and 1998, a pharmacological surveillanc...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:2000-05-01 00:00:00
abstract::Aiming to correlate the alterations in evoked potentials with the initial clinical manifestations of multiple sclerosis, 29 patients with the disease were studied and 19 were followed for a lapse ranging from 1 to 11 years. Visual evoked potentials were studied in all the patients and 51% were abnormal. Auditory evoke...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::Microalbuminuria is a new tool in the management of patients with diabetes mellitus or hypertension. Microalbuminuria is an easily measured biomarker in a urine sample. Urinary albumin to creatinine ratio in first morning urine sample correlates with 24 hours urinary albumin excretion, but it is easier to obtain, and ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872012000600016
更新日期:2012-06-01 00:00:00
abstract::The aim of this work was to assess the degree of interaction between diethylpropion and some cellulosic derivatives widely used in anorexigenic prescriptions. Our in vitro results show that sodium carboxymethylcellulose and methylcellulose cause a significant degradation of diethylpropion, the first having a greater e...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:Women in childbearing ages (WCBA) represent a strategic intervention group to reverse the global trend of increasing obesity. AIM:To conduct a review of studies reporting obesity prevalence in WCBA in Chile in the last 25 years. MATERIAL AND METHODS:To describe obesity prevalence, we used three approaches,...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872014001100011
更新日期:2014-11-01 00:00:00
abstract::In a double blind study, 20 patients who presented with acute episodes of asthma were randomized to treatment with nebulized salbutamol (5 mg) of subcutaneous salbutamol (0.5 mg). The clinical conditions were not significantly different before or after treatment in both groups. Significant bronchial dilation was obtai...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-02-01 00:00:00
abstract::We report the case of a 42 years old male, with a bipolar disorder and receiving lithium therapy, valproic acid and clonazepam. Due to an exacerbation of his underlying disease, he was admitted to a psychiatric clinic and received 50 mg of intramuscular chlorpromazine in two occasions. Afterwards, the patient had an a...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-02-01 00:00:00
abstract::Kikuchi and Fujimoto disease is a benign subacute necrotizing lymphadenitis, probably associated to a viral infection, that affects mostly young Asian women. We report a 19 years old women, with a vast familiar history of thyroid disease (three uncles with papillary thyroid carcinoma and one with a Hashimoto thyroidit...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::Chronic kidney disease is a worldwide health problem. The incidence and prevalence of kidney failure is in constant increase, involving poor outcomes and high costs. The leading causes of kidney failure are type 2 diabetes and hypertension. The new initiative "Kidney Disease Improving Global Outcomes (KDIGO)" is a glo...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872005000300011
更新日期:2005-03-01 00:00:00
abstract::Regardless of the diagnostic criteria, the metabolic syndrome is found at least in 20% of the population. The adipose tissue plays an important role in the insulin resistance found in this syndrome. Free fatty acids released by intra-abdominal adipocytes produce an inflammatory and pro-thrombotic response and the pers...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872009000500014
更新日期:2009-05-01 00:00:00
abstract:AIM:To compare the efficacy of imipenem/cilastatine and ceftazidime-amikacin in the treatment of febrile neutropenic patients. DESIGN:Open, prospective and randomized clinical study. PATIENTS:Fifty two patients (26 female) aged 16 to 80 years old with 60 episodes of neutropenia were studied. They were randomly assign...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-03-01 00:00:00
abstract::Augusto Orrego Luco born in 1848 and dead in 1933 in Valparaiso, was one of the greatest clinicians and researchers of chilean medicine during the late nineteenth and early twentieth century. Besides being a psychiatrist he contributed to literature, history, politics and medicine. He received his medical degree in 18...
journal_title:Revista medica de Chile
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma is the most frequent primary tumor of the liver. It is associated to chronic liver diseases and has a high prevalence in some regions of Africa and Asia. AIM:To describe the clinical characteristics of patients with hepatocellular carcinoma, admitted to two hospitals of the IX regio...
journal_title:Revista medica de Chile
pub_type: 杂志文章,多中心研究
doi:
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Recent studies in mice have demonstrated that the Msx-1 homebox gene is implicated in cleft palate. Thus, it has been suggested that its human homologue, MSX1 (HOX-7), located in chromosome 4 could be involved in the etiology of non syndromic cleft lip palate. AIM:To study the linkage between non syndromic ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract::We studied genetic polymorphism of isoniazid acetylation in 47 tuberculous patients treated with 4 drugs between Aug 1987 and Dec 1988. Inactivation of isoniazid was estimated from urine samples after administration of the drug (10 mg/kg). There were 18 slow and 29 fast acetylators. The frequency of the slow mutant ge...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract:BACKGROUND:Beliefs about professionals' healthcare may influence healthcare behaviors. Such beliefs are in part the result of the interactions that professionals have with their patients. Recent studies highlight the importance of beliefs about physicians, their effect on health-care behaviors, and the requirement of c...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000300308
更新日期:2018-03-01 00:00:00