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[Cardiovascular risk factors in middle-age women with acute coronary syndromes].

Abstract：

BACKGROUND:In Chile, 40% of deaths due to acute myocardial infarction occur in women. AIM:To assess the presence of cardiovascular risk factors in women with acute coronary syndromes. PATIENTS AND METHODS:Thirty four women aged 46 to 55 years old, admitted to the hospital due to an acute coronary syndrome and 102 age matched healthy women were studied. A clinical history was obtained, blood pressure and fasting serum lipids were measured. RESULTS:A history of high blood pressure was present in 65 and 16% of patients and healthy controls respectively. Seventy seven percent of patients and 36% of controls smoked, 76% of patients and 48% of controls were postmenopausal, 21% of patients an 5% of controls were diabetic. In patients and controls respectively serum total cholesterol was 230.1 +/- 36.2 and 211.2 +/- 34.8 mg/dl, serum triacylglycerol was 213.4 +/- 109.4 and 143.2 +/- 76.9 mg/dl and serum HDL cholesterol was 44.1 +/- 10.8 and 49.8 +/- 13.3 mg/dl (p < 0.001 or less). In univariate analysis, the risk of acute coronary syndrome increased with high blood pressure (OR: 9.3, CI: 2.5-18.6), menopause (OR: 8.3, CI: 2.2-31:5), smoking (OR: 6.9, CI: 2.5-18.6), diabetes mellitus (OR: 5.0, CI: 1.4-17.5), a high total cholesterol/HDL cholesterol ratio (OR: 6.6, CI: 1.8-12.5) and hypertriglyceridemia (OR: 3.6, CI: 1.5-8.5). Logistic regression analysis showed that hypertension and menopause had the higher predictive values for acute coronary syndrome. CONCLUSIONS:In this group of women with acute coronary syndromes, the main coronary risk factors were high blood pressure and menopause.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Blümel JE,Prieto JC,Leal T,Cruz MN,Gallardo L

subject

Has Abstract

pub_date

2001-09-01 00:00:00

pages

995-1002

issue

9

eissn

0034-9887

issn

0717-6163

journal_volume

129

pub_type

杂志文章

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