Abstract:
:Regardless of the diagnostic criteria, the metabolic syndrome is found at least in 20% of the population. The adipose tissue plays an important role in the insulin resistance found in this syndrome. Free fatty acids released by intra-abdominal adipocytes produce an inflammatory and pro-thrombotic response and the persistence of the insulin resistance state, phenomenon termed lipotoxicity. This altered phenotype explains the development of the different components of the metabolic syndrome, such as hypertension, dyslipidemia and altered glucose metabolism. The treatment is based on weight loss and healthy lifestyle. A balanced diet, physical activity and avoidance of smoking are key management features. The use of drugs with pleiotropic effects, which inhibit the renin angiotensin aldosterone axis or acts on the peroxisome proliferators-activated receptors (PPAR) seems promising.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Martínez R G,Alonso K R,Novik A Vdoi
/S0034-98872009000500014subject
Has Abstractpub_date
2009-05-01 00:00:00pages
685-94issue
5eissn
0034-9887issn
0717-6163pii
S0034-98872009000500014journal_volume
137pub_type
杂志文章,评审abstract:BACKGROUND:Streptococcus agalactiae or group B streptococcus, GBS, is the leading cause of neonatal and maternal infections and an opportunistic pathogen in adults with underlying disease. In the last decade, a dramatic increase in the resistance of this microorganism to erythromycin and clindamycin has been observed. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872004000500003
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:There is a wide interindividual variability in the response to a period of exercise training. The science have reported that a minimum of participants could be non-responders for improving different health-related outcomes after training. AIM:To compare the effects of a 6-weeks exercise program on body comp...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000600693
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Vitamin K antagonist medications (VKA) are essential for the prevention of thromboembolic events, but their effectiveness is influenced by multiple factors, such as the type of medication chosen. AIM:To evaluate the efficacy in anticoagulant control of the bioequivalent and non-bioequivalent drugs of acenoc...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872020000901254
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:The age at which children born preterm normalize their bone mineral density, is not well known. AIM:To study if children born preterm have normalized their bone mineral density at age 5 to 7 years. PATIENTS AND METHODS:Twenty six infants born preterm (14 male), were studied at age 5 to 7 years. Birth weigh...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Parents have a control role in the development and treatment of eating disorders among teenagers. AIM:To compare attitudes, beliefs and behaviors between mothers of patients with eating disorders and mothers of teenagers without these disorders. MATERIAL AND METHODS:Twenty one mother-sibling pairs of adole...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009000600008
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:In patients with colorectal carcinoma, insertions or deletions of short sequences of DNA, a phenomenon called microsatellite instability, are observed. AIM:To look for microsatellite instability and mutations of MLH1 and MSH2 gene mutations in patients with colorectal carcinoma. MATERIAL AND METHODS:Ten pa...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006001000002
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Mental disorders may interfere, aggravate or mimic medical conditions. AIM:To study the prevalence of psychiatric disorders among patients hospitalized in a medical ward of a general hospital. PATIENTS AND METHODS:A structured interview for DSM-III, devised for "non patients", was applied to 203 men and 20...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Skin prick test (SPT) of immediate hypersensitivity is a main instrument in the diagnosis of allergy. AIM:To demonstrate the applicability of skin prick test in different age groups. PATIENTS AND METHODS:We studied children and adolescents with the diagnosis of allergy in the Pediatric Respiratory Laborato...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872005000200007
更新日期:2005-02-01 00:00:00
abstract::Secondary acute myeloid leukemia is a very rare complication in patients with solid organ transplantation. We report a 62 years old female who received a right single lung allograft for idiopathic pulmonary fibrosis. Her immunosuppression scheme consisted in prednisone, azathioprine, and tacrolimus. Two years after th...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872015000200015
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Aortic valve stenosis is the most prevalent valvulopathy in the elderly, but it is frequently undertreated. AIM:To assess early and long term results of valve replacement with bioprostheses in patients 70 years old or older with aortic stenosis. PATIENTS AND METHODS:A review of the database of the Cardiova...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000200002
更新日期:2011-02-01 00:00:00
abstract::Bronchogenic cysts are congenital malformations of the tracheo-bronchial tree usually located intrathoraxically. We report a 44 years old male with a bronchogenic cyst located exceptionally in the pre tracheal anterior cervical region, simulating a thyroid lesion. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:Professional Social Responsibility is now imperative for the practice of medicine. However, there are no instruments to assess it among physicians. AIM:To construct and evaluate the factorial structure and reliability of a questionnaire designed to measure socially responsible behavior in physicians. MATER...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014000100014
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Chromosome aberrations (CA) are the main etiology of multiple congenital malformations, recurrent abortions and intellectual disability (ID) specifically of moderate and severe degree. They account for 0.3 to 1% of newborns (NB) and 6 of 10,000 NB have chromosome imbalances with submicroscopic deletions or d...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000300003
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Understanding how autonomous students are capable of regulating their own learning process is essential to develop self-directed teaching methods. AIM:To understand how self-directed medical students approach learning in medical schools at University of Concepción, Chile. MATERIAL AND METHODS:A qualitative...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872015001200011
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Ultraviolet light exposure has a pathogenic effect on the development of skin cancer, whose prevalence increases worldwide. In Chile and the rest of the world, preventive educational campaigns are carried out to change high risk sun exposure behaviors. AIM:To study the behavior of the Chilean population tow...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872005000600007
更新日期:2005-06-01 00:00:00
abstract::Docosahexanoic acid (C22:6, DHA) is a highly unsaturated omega-3 fatty acid that forms part of the central nervous and visual system structures. DHA is synthesized from its precursor, alfa-linolenic acid, that is also a omega-3 fatty acid and can be obtained from vegetable oils. Marine organisms, specially fish, are g...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Maximal oxygen uptake is considered by the International Biological Programme as the international standard of cardiorespiratory adequacy and physical condition. AIM:To measure maximal oxygen uptake in normal Chilean subjects, to establish normal reference values. SUBJECTS AND METHODS:Maximal oxygen uptake...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:The implementation of the marketing strategies in public hospitals provides management advantages and improves the relationship between customers and staff. AIM:To analyze the application of marketing strategies in a public hospital, from the perspective of the staff. MATERIAL AND METHODS:A structured surv...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006000300014
更新日期:2006-03-01 00:00:00
abstract:AIM:to assess the usefulness of fiberoptic bronchoscopy in the etiologic diagnosis of pulmonary infiltrates in patients with AIDS. PATIENTS AND METHODS:in 25 patients with AIDS and pneumonia, 31 fiberoptic bronchoscopies with bronchoalveolar lavage were performed; in 11 occasions, a transbronchial biopsy was also perf...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract::Beta 2 microglobulin is a low molecular weight protein integrating the light chain HLA antigens. Its serum concentration is increased in different neoplasias and in renal failure. Using solid phase RIA we determined the concentration of beta 2 microglobulin in plasma and spinal fluid of 57 healthy individuals and pati...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND:Cellular immune mechanisms of the resistance to infection by T cruzi as well as the pathogenesis of Chagas disease are still controversial. AIM:To quantify and analyse the peripheral blood immune cells from chagasic and non chagasic patients by flow cytometry. PATIENTS AND METHODS:Peripheral blood samples ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract::During 1987 and 1988 sexually transmitted diseases affected 87.2 per 100,000 inhabitants of the Viña del Mar-Quillota area. At all ages rates were 3.8 times higher in males compared to females. Gonorrhoea, syphilis and non gonorrheal urethritis accounted for most cases. In males, 82% of cases corresponded to gonorrhoe...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::This paper undertakes an analysis of the scientific criteria used in the diagnosis of death and underscores the importance of intellectual rigor in the definition of medical concepts, particularly regarding such a critical issue as the diagnosis of death. Under the cardiorespiratory criterion, death is defined as "the...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872004000100015
更新日期:2004-01-01 00:00:00
abstract::An analysis of the interaction of evolutionary factors such as migration, mutation, selection random drift, and consanguinity upon the genome of Easter islanders is attempted. As many primitive populations, the Easter islanders genome has at least 2/3 of genetic loci in an isogenic state. The HLA system is reduced; ot...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND:Islet cell-specific autoantibodies such as islet cell antibody (ICA), antiinsulin (IAA), anti-glutamic acid decarboxylase (GAD) and anti-tyrosine phosphatase (IA2) can be present in patients with type I diabetes. Breast feeding duration and the early exposure to milk substitutes are environmental factors ass...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:in fulminant hepatic failure, different organs systems become involved and a multiple systems organic failure may ensure. AIM:to perform a retrospective analysis of patients with fulminant hepatic failure admitted to UC Hospital Intensive Care Unit. PATIENTS AND METHODS:the charts of fourteen patients (8 m...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract:UNLABELLED:Circulating concentrations of the high affinity growth hormone binding protein (GHBP) may be a marker of GH receptor density as well as GH sensitivity. GOAL:To determine values of GHBP for a normal Chilean pediatric population. METHODS:We determined GHBP levels in 73 males and 73 females between 4 to 15.5 ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract::Chile made several legal, practical and educational changes to the organ donation and transplant system in recent years, to improve its results. However, studies evaluating these reforms and suggesting further corrections are still pending. Our aim is to assess the new regulations and their reception by both the popul...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000600780
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Ménétrier disease is a rare disorder of the stomach, characterized by giant hypertrophic folds that usually involve the gastric body and fundus, associated to hypoalbuminemia due to serum protein loss across the gastric mucosa. We report a 55-years-old male presenting with abdominal pain, vomiting, weight lo...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000900011
更新日期:2012-09-01 00:00:00
abstract::In an open, pilot study, the efficacy and safety of ursodeoxycholic acid (UDCA) in the treatment of intrahepatic cholestasis of pregnancy was investigated. Four patients received 1 g/day of UDCA during 20 days and another 2 patients received 2 identical periods of treatment separated by a 14-day interval free of drug....
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00