Abstract:
:An analysis of the interaction of evolutionary factors such as migration, mutation, selection random drift, and consanguinity upon the genome of Easter islanders is attempted. As many primitive populations, the Easter islanders genome has at least 2/3 of genetic loci in an isogenic state. The HLA system is reduced; other polymorphisms present high genic frequencies differentiating Easter islanders from other Andean and european populations. They are more similar to polynesians, with whom they share language and culture. Migration has been the main factor affecting the Easter islanders genome, leading to a ten fold increase in population and a 60% caucasian admixture. A linkage disequilibrium of the HLA9, w10 haplotype exists. In XIX century generations consanguinity was very low (alpha coefficient 7 x 10(-5) which may be explained by the exogamic tradition of the population; this acted as a factor opposed to random drift. A recent decrease in infant mortality rate leads to a relaxation of natural selection and contributes to hybridization of the population.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Cruz-Coke Rsubject
Has Abstractpub_date
1989-06-01 00:00:00pages
685-94issue
6eissn
0034-9887issn
0717-6163journal_volume
117pub_type
杂志文章,评审abstract:BACKGROUND:Primary plasma cell leukemia (pPCL) is uncommon, aggressive and has a different biology than multiple myeloma (MM). AIM:To report the features of patients with pPCL. MATERIAL AND METHODS:Review of databases of the Hematology Department and the Hematology laboratory. RESULTS:Of 178 patients with monoclonal...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000100018
更新日期:2019-01-01 00:00:00
abstract::Specialists must be trained in properly certified university centers. There are established applicant selection programs and mechanisms and faculties maintain a favorable learning environment. The careful selection of teachers must be based in their personal attributes, their interest and dedication to academic work a...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Psychological problems are a frequent cause of consultation in primary care outpatient clinics. AIM:To report the results for Santiago de Chile of the World Health Organisation multicentric collaborative study on Psychological Symptoms in General Health Care. PATIENTS AND METHODS:The results of 1453 patien...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND:Crowding in Emergency Departments (ED), results from the imbalance between the simultaneous demand for health care and the ability of the system to respond. The NEDOCS scale (National Emergency Department Crowding Scale) measures the degree of crowding in an ED. AIM:To describe ED Crowding characteristics, ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000500001
更新日期:2017-05-01 00:00:00
abstract::Human immunodeficiency virus infection raises ethical issues in medical practice. This work presents several problems with ethical connotations related to HIV infections, observed by a neurologist during his medical practice. Patient-physician relationships, confidentiality, the request of patient consent to perform d...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:Colorectal cancer (CRC) is the third most prevalent cancer in the world and is the second cause of cancer death. Positron emission tomography/computed tomography (PET/CT) using 18F-FDG is used for its staging and follow up. AIM:To assess the occurrence of synchronous colonic and extracolonic tumors detected...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000700828
更新日期:2019-07-01 00:00:00
abstract::Atherosclerosis is a systemic disease that may involve more than one territory. Myocardial infarction can occur after carotid endarterectomy and stroke is a well documented morbidity of coronary artery bypass grafting. To optimize results, we have performed concomitant carotid endarterectomy and myocardial revasculari...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract:BACKGROUND:Approximately 150 subjects per year suffer severe burns in Chile. AIM:To analyze sociodemographic/clinical features and outcomes of severely burned patients. MATERIAL AND METHODS:Retrospective cohort study of 936 patients aged 47 ± 20 years (66% males), admitted to the National Burn Center of Chile between...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872013000200006
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:In large series, nearly 60% of admissions for suspected acute coronary syndrome (ACS) had a non-coronary etiology of the pain. However, short term mortality of non recognized ACS patients, mistakenly discharged from the emergency room is at least twice greater than the expected if they would had been admitte...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872007000700003
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Basedow Graves disease (BGD) is the leading cause of hyperthyroidism. The characteristics of patients seen at a university hospital may differ from those described in the general population. AIM:To describe the clinical features of patients with BGD seen at a university hospital. MATERIAL AND METHODS:Revie...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000400003
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Aging is the main risk factor to acquire breast cancer (BC). Nevertheless BC in elderly patients is sub-represented in clinical trials. AIM:To describe the clinical characteristics and long term treatment results of localized BC in older women. MATERIAL AND METHODS:Review of medical records of 65 women age...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872013001200006
更新日期:2013-12-01 00:00:00
abstract::We report a 65 years old female undergoing hemodialysis, presenting with intense pain in the lower right quadrant and moderate hematochezia. Since symptoms did not abate after an appendectomy, a colonoscopy and barium enema were performed, whose results suggested an advanced cecal carcinoma. Biopsies were negative for...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract:UNLABELLED:Studies have reported which expectations and demands adolescents have for more accessible sexual and reproductive health (SRH) services. However, there is limited information regarding parents' requirements and demands for SRH services their adolescents need. AIM:To explore the knowledge of parents regardin...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014001000005
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:There is no conclusive evidence about the association between physical fitness (PF) and health related quality of life (HRQOL) in older adults. AIM:To seek for an association between PF and HRQOL in non-disabled community-dwelling Chilean older adults. MATERIAL AND METHODS:One hundred and sixteen subjects ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000100008
更新日期:2017-01-01 00:00:00
abstract::Master of Internal Medicine is the highest award granted by the Chilean Society of Internal Medicine (Sociedad Médica de Santiago) to its members. Since this award was instituted, in 1981, the Society has given it periodically to the most distinguished Chilean physicians. All nominees are considered a model as a physi...
journal_title:Revista medica de Chile
pub_type: 传,历史文章,杂志文章
doi:/S0034-98872007001100015
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Chronic obstructive pulmonary disease (COPD) has a relevant impact on health-related quality of life (HRQoL). Short Form 6 dimensions (SF-6D) quality of life tool allows researchers to calculate preference-based utilities using data from SF-12 or SF-36 questionnaires. AIM:To provide normative values of SF-6...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000200001
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Postpartum depression (PPD) is a public health issue, and appropriate screening may lead to clinical gains. AIM:To describe the screening for PPD, its relationship with the use of health care services, and treatment access barriers in Chilean public primary health care (PHC) centers. MATERIAL AND METHODS:P...
journal_title:Revista medica de Chile
pub_type: 杂志文章,多中心研究
doi:10.4067/s0034-98872018000901001
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Clients and providers of health care can have contrasting perceptions about the quality of service. Provider perceptions are mostly devoted to design and delivery of services while those of clients are focused in the attention received. AIM:To assess perceptions of health care providers and clients about cl...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010000500015
更新日期:2010-05-01 00:00:00
abstract::We report the case of a woman with rapidly progressive IgA nephropathy. She was treated with pulse methylprednisolone sodium succinate (1 g/d for three days), cyclophosphamide, dipyridamole and aspirin. The rapid progression of renal failure was apparently halted after 6 months. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::Tumorogenesis is associated with several events by which a normal cell transforms itself into a tumour cell with an increased proliferation rate. One of the most important research initiatives in this area is the characterization of the molecular mechanisms involved in tumorogenesis and cancer. Oncogenes and tumour su...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:A high proportion of women consulting for depression have a history of childhood abuse and trauma. AIM:To compare the efficacy and costs associated with a treatment that enquires directly into childhood trauma and understands present interpersonal difficulties as a compulsion to repeat the traumatic past, v...
journal_title:Revista medica de Chile
pub_type: 杂志文章,随机对照试验
doi:/S0034-98872010000400006
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Toxic epidemial necrolysis (TEN) is an acute adverse drug reaction, that has an unpredictableprogression and a 30% mortality. The incidence of TEN in the general population is approximately 0.4 to 1.2 cases/million/year. It is characterized pathologically by keratinocyte apoptosis which leads to epidemial de...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009000300009
更新日期:2009-03-01 00:00:00
abstract::We report a 64 years old female admitted with fever, cough, dyspnea and lung opacities in the chest X ray. A chest tomography scan (CTS) showed multiple-bilateral ring-shaped opacities and the reversed halo sign (RHS). The patient did not improve with antimicrobial therapy (AT). Infection and rheumatologic causes were...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000500663
更新日期:2019-05-01 00:00:00
abstract::To be successful, modern medical acts require the participation of several professionals and assistants and, as such, there has been a steady trend from individual medicine to the collective practice of the profession. This format raises issues in determining when a medical professional or other practitioner is liable...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000500016
更新日期:2011-05-01 00:00:00
abstract::Geographical inequalities arising in the death of children under 1 year are studied. Causes regarded as avoidable at the present moment and leading to death are determined and the 27 Regional Chilean Health Services are ranked from best to worse in levels of mortality using cluster analysis. Results show that: 1) t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1982-04-01 00:00:00
abstract:BACKGROUND:There is a very strong documented correlation between the appearance of cancer cells in blood and occurrence of metastasis in gastrointestinal cancer. AIM:To determine MUC1, CK19, CK20 and CEA mRNA expression in bone marrow of patients with gallbladder cancer and evaluate its clinical significance. MATERIA...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract::Although the use of cadaveric split or living donor liver transplantation is a valid option for liver transplants, they have several complications, being the "small-for-size syndrome" one of the most frequent. This entity is mainly due to the incapacity that the graft has to meet the blood drainage demands. We report ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009000700009
更新日期:2009-07-01 00:00:00
abstract::We report a 56 years-old man presenting with chest pain with exercise, seven years after an orthotopic heart transplant. A coronary angiography showed an atherosclerotic lesion in the common left main coronary artery with more than 90% obstruction. The lesion was successfully treated with a transluminal angioplasty wi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872007001200012
更新日期:2007-12-01 00:00:00
abstract::The classic hepatotropic viruses, hepatitis A through E, are not the only viral agents able to infect the liver. Other systemic viruses may cause hepatic injury that can range from mild and transient elevation of aminotransferases to acute hepatitis and occasionally acute liver failure and fulminant hepatitis. The cli...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872010001100016
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:The mucosa distal to the endoscopic mucosal change zone can have easily diagnosed early alterations, in patients with chronic gastroesophageal reflux. AIM:To determine the type of mucosa existent in the zone distal to the squamous-columnar junction in patients with chronic gastroesophageal reflux without in...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00