Abstract:
BACKGROUND:The mucosa distal to the endoscopic mucosal change zone can have easily diagnosed early alterations, in patients with chronic gastroesophageal reflux. AIM:To determine the type of mucosa existent in the zone distal to the squamous-columnar junction in patients with chronic gastroesophageal reflux without intestinal metaplasia. PATIENTS AND METHODS:One hundred thirty four controls and 208 patients with chronic gastroesophageal reflux lasting two years were studied. Forty three of these patients had a normal endoscopy, 54 had an erosive esophagitis and 111 had a short columnar epithelium covering the distal esophagus, without intestinal metaplasia. In all subjects, four biopsies were obtained from a zone distal to the squamous-columnar junction and two from the distal gastric antrum. RESULTS:In 59% of control subjects, fundic mucosa was present in the zone distal to the squamous-columnar junction. Cardial mucosa was present in the rest. In patient with chronic gastroesophageal reflux, cardial mucosa was predominant. Helicobacter pylorii infection decreased along with increasing extension of cardial mucosa covering the distal esophagus. CONCLUSIONS:In patients with chronic gastroesophageal reflux there is a metaplasia of fundic mucosa towards cardial mucosa. On the other hand, Helicobacter pylorii infection decreases gradually.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Csendes A,Smok G,Christensen H,Rojas J,Burdiles P,Korn Osubject
Has Abstractpub_date
1999-12-01 00:00:00pages
1439-46issue
12eissn
0034-9887issn
0717-6163journal_volume
127pub_type
杂志文章abstract::The great diversity of commercially available products for the serologic diagnosis of Chagas disease led us to conduct a study of these products in comparison with the indirect immunofluorescence test. Percent agreement between methods ranged from 79 to 100%, the details for each product being given in the text. Bette...
journal_title:Revista medica de Chile
pub_type: 杂志文章
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abstract:BACKGROUND:Several genetic polymorphisms of adiponectin have been associated to metabolic diseases as obesity and co-morbidities. AIM:To investigate if there are associations between +45TG, +276GT, -11,377CG y -11,391GA adiponectin SNPs (single nucleotide polymorphism) with obesity in a Chilean children population. M...
journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
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更新日期:1999-11-01 00:00:00
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
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doi:
更新日期:2000-01-01 00:00:00
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journal_title:Revista medica de Chile
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更新日期:1994-07-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011001200003
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journal_title:Revista medica de Chile
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doi:/S0034-98872009001100013
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journal_title:Revista medica de Chile
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doi:
更新日期:2004-12-01 00:00:00
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
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