Abstract:
BACKGROUND:The great variability in the clinical presentation of Chagas disease may depend in part in the genetic variability of Trypanosoma cruzi populations. AIM:To compare prepatent period, parasitemia, mortality and histological lesions in mice infected with two populations of Trypanosoma cruzi isolated in Chile. MATERIAL AND METHODS:Two Trypanosoma cruzi populations, isolated from Chilean Triatomides and genetically characterized by kinetoplast restriction fragment DNA profiles, were compared. Two groups of 40 Balb/c mice were studied. Each mouse was inoculated with 10(4) trypomastigotes, of the V-121 and sp COMB 2 Trypanosoma cruzi populations. The prepatent period, parasitemia, mortality and histopathological lesions, at different evolutionary stages of infection were registered during 32 days. RESULTS:Prepatency and mortality were similar in both groups of mice. However, parasitemia was significantly greater in mice inoculated with V-121 than those inoculated with sp COMB 2. Amastigote pseudocysts and inflammation were present only in skeletal muscle and myocardium in both groups of mice. The intensity of tissue involvement was associated to the level of parasitemia, therefore it was greater in mice inoculated with V-121 population. CONCLUSIONS:V-121 population of Trypanosoma cruzi caused a greater parasitemia than COMB 2, in inoculated mice.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Pizzi P T,Wallace R A,Villagra O R,Muñoz V S,Ortiz Z S,Solari I Adoi
10.4067/s0034-98872005000400006subject
Has Abstractpub_date
2005-04-01 00:00:00pages
432-8issue
4eissn
0034-9887issn
0717-6163pii
S0034-98872005000400006journal_volume
133pub_type
杂志文章abstract:BACKGROUND:Approximately 150 subjects per year suffer severe burns in Chile. AIM:To analyze sociodemographic/clinical features and outcomes of severely burned patients. MATERIAL AND METHODS:Retrospective cohort study of 936 patients aged 47 ± 20 years (66% males), admitted to the National Burn Center of Chile between...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872013000200006
更新日期:2013-02-01 00:00:00
abstract::Gestational Diabetes is characterized by different degrees of glucose intolerance that produce a series of fetal and perinatal alterations. During many years, in those cases of gestational diabetes that did not respond to nutritional interventions, the use of insulin was a proven treatment to achieve metabolic control...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872008000700015
更新日期:2008-07-01 00:00:00
abstract::We report a 16-year-old boy, who suffered a right vent ride penetrating injury caused by a sharp blade that evolved to cardiac tampon. He underwent surgery and was discharged four days later. Thirteen days later, a cardiac murmur was found. An echocardiography showed an aorta-right ventricular fistula. Surgical closur...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010000200010
更新日期:2010-02-01 00:00:00
abstract::Between January 1980 and December 1990, 16 patients with acute mitral insufficiency were operated on an emergency basis at our institution. They represented 1.8% of all mitral surgical cases. All of them were in acute pulmonary edema and 7 in cardiogenic shock. The etiology was ischemic in 6, degenerative in 4, infect...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::This article reports the results of 1080 ultrasonographic examinations of the liver in a clinic of the Ninth Region of Chile, using a SSD 620 Aloka equipment. In 61 examinations (5.6%) a focal liver lesion was found. Of these, 9 (14.7% of lesions) appeared as malignant (6 metastasis and 3 hepatomas) and 52 (85.3% of l...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::Tumorogenesis is associated with several events by which a normal cell transforms itself into a tumour cell with an increased proliferation rate. One of the most important research initiatives in this area is the characterization of the molecular mechanisms involved in tumorogenesis and cancer. Oncogenes and tumour su...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:In Chile, there is a high prevalence of cardiovascular diseases. Because atherosclerosis starts in childhood, it is important to assess serum lipid levels in children. AIM:To measure serum lipid levels in normal Chilean newborns. SUBJECTS AND METHODS:A sample of umbilical cord venous blood was obtained fro...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:In July 2010 end stage renal disease anemia correction was incorporated to the program of explicit health guaranties of the Ministry of Health. The treatment plan included intravenous iron and erythropoietin. The prescription of these medications carne from the deriving health organizations. AIM:To describe...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872013000500003
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:The few studies in Chile assessing the nutritional status of indigenous children show a high prevalence of stunting, excess weight and feeding problems. AIM:To compare anthropometric indices in children from indigenous and non indigenous ancestry. SUBJECTS AND METHODS:School children aged 6 to 8 years old,...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-08-01 00:00:00
abstract::A national network including 114 blood banks and laboratories performs screening for HIV infection on approximately 250,000 blood donors a year. This represents 100% coverage of blood transfusions performed in Chile. Up to December 1990. 4956 samples had been sent to the National Reference Center for AIDS for suppleme...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::Dual-photon bone densitometry of the lumbar spine and hips was performed in 11 patients (9 females) with asymptomatic primary hyperparathyroidism and in 11 control subjects. The age was 54.7 +/- 14.8 years. The asymptomatic state of the disease was established by the absence of clinical or radiologic evidence of renal...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract::The most significant facts in the development of Chilean cardiology since 1930 are reviewed. The preeminence of great clinicians in the thirties was followed by the creation of Departments of Cardiology in University Hospitals. The emergence of powerful diagnostic tools and cardiac surgery allowed an accelerated devel...
journal_title:Revista medica de Chile
pub_type: 历史文章,杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::The earth of ornamental plants is one of the main reservoirs of Aspergillus type of fungi in hospital areas. We studied 174 ornamental interior plants from a hospital at Santiago. Samples were obtained from the soil surface and sowed in Sabouraud-glucose agar, adding streptomycin and G-penicillin. After 72 h of cultur...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract:BACKGROUND:Clinical reasoning is the most important competente in the training process of a physician. AIM:To develop a method for teaching clinical reasoning based on prototypes of clinical cases. MATERIAL AND METHODS:The study was conducted on sixty-four third year medical students. The study and control groups att...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872013000700001
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:There are several diagnostic criteria for Metabolic Syndrome (MS) definition. AIM:To study their application in the Chilean general adult population. MATERIAL AND METHODS:We analyzed data from a random sub sample of 1.833 adults aged 17 years and older surveyed during the First Chilean National Health Surv...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872010000600007
更新日期:2010-06-01 00:00:00
abstract::Due to differences in treatment effect in studies on the effectiveness of digoxin in patients with congestive heart failure in sinus rhythm, a cross-over placebo-controlled, randomized double blind clinical trial was performed. Thirty one patients, without previous treatment with digoxin, in New York Heart Association...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-10-01 00:00:00
abstract::We report a 29 years old male, with a history of cocaine abuse and excessive alcohol intake, who was admitted to the hospital with an acute peritonitis. The patient was operated and multiple perforations of the cecum were found. A right hemicolectomy was performed and the pathological study of the surgical piece showe...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Type I human immunodeficiency virus (HIV) is characterized by a great genetic variability. There are three groups of virus throughout the world: O, N and M. Group M is responsible for AIDS pandemic and is subdivided in 9 genetic subtypes. Most viral strains in South America are subtype B. AIM:To determine t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Glycine inhibits the formation of advanced glycation end products that may cause central and peripheral neuronal damage, affecting also the auditory nerve. AIM:To evaluate the effect of glycine on auditory nerve conduction and hearing level among patients with type 2 diabetes mellitus and auditory neuropath...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010001100006
更新日期:2010-10-01 00:00:00
abstract::Low plasma HDL cholesterol levels are an independent risk factor for atherosclerotic cardiovascular disease. During the past years, the study of HDL has been stimulated by the discovery of novel genes and proteins, which have provided new insights into the molecular and cellular mechanisms involved in HDL metabolism. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872005000700011
更新日期:2005-07-01 00:00:00
abstract::In 160 girls from low and middle socio-economic class of Santiago we correlated the age at menarque with genetic markers such as ABO blood group, Rh, MN, Xg, haptoglobins, Esterase D and Phosphoglucomutase. No significant association of these markers and age at menarque was found. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract:BACKGROUND:Hürthle cells can be found in non malignant thyroidal diseases such as Basedow Graves and Hashimoto diseases. When Hürthle cells comprise more the 75% of cellularity, they become a neoplasm. There are malignant variants of these neoplasms, constituted by follicular and papillary Hürthle cell carcinomas. AIM...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND:Respiratory pathogens are becoming increasingly resistant to antimicrobials. A new group of drugs, called respiratory quinolones have been synthesized to overcome this problem. AIM:To study the in vitro susceptibility of respiratory pathogens to old and new antimicrobials. MATERIALS AND METHODS:Forty five ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract::The aim of this work was to analyze the global incidence of congenital malformations at the Maternity of University of Chile Clinical Hospital in the periods between 1971 and 1977 and between 1982 and 1992. A significant and sustained increase in incidence was observed in the first period from 10.64 per 1000 born aliv...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:Acute bacterial meningitis (ABM) is a serious disease that needs rapid diagnosis for an accurate treatment. The most important etiological agents are: Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae type b. Overall pathogen detection rate in patients with ABM in Chile is 83%. AIM...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008000300009
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:The number of nonagenarians is rapidly growing in Chile. This age group is mainly female, with higher frailty markers and in higher risk of being placed at nursing homes. AIM:To describe features of nonagenarian women and compare them with a group of women between 60-89 years, both living in nursing homes, ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872004000100005
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Soft tissue foreign bodies are a frequent cause of consultation in emergency rooms. It is difficult to verify their existence since conventional radiology only detects radio opaque objects. Ultrasound can be a useful diagnostic procedure. AIM:To report our experience in the detection of soft tissue foreign ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract::The incidence of hepatitis, mumps, poliomyelitis, scarlet fever, pertussis and measles from 1954 to 1984 was studied from the annual records of infectious diseases. Fluctuations were evaluated by Fourier analysis. Periodic recurrency was detected for poliomyelitis, scarlet fever, pertussis and measles and was likely f...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Since February 2002, Flextend electrode catheters are used at the Cardiovascular Unit of the Catholic University Clinical Hospital. These transvenous catheters have an IS-1 connector, silicone coating, active fixation and retractile helix with dexamethasone acetate. AIM:To report early and one year results ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872006000600011
更新日期:2006-06-01 00:00:00
abstract::Persistent left superior vena cava is the most common venous congenital malformation and is usually asymptomatic. Its presence could increase the difficulty for transvenous lead implantation. We report a 71-year-old woman with an idiopathic dilated cardiomyopathy, atrial fibrillation and heart failure that required bi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872012000100012
更新日期:2012-01-01 00:00:00