Abstract:
:Relaxin was localized in cells of corpora lutea of pregnant rats at the ultrastructural level using a highly specific antirat relaxin serum and the unlabeled peroxidase-antiperoxidase technique. Electron-dense, membrane-bound granules (maximum diameter, 270 nm), which are present in luteal cells during the last third of gestation, were the only inclusions that were immunochemically stained. The number of granules observed in the luteal cell cytoplasm varied from cell to cell within a particular section. Furthermore, in the granule-rich luteal cells, the granules appeared in clusters. This study establishes that these electron-dense granules represent the subcellular sites of relaxin localization within luteal cells of pregnant rats.
journal_name
Endocrinologyjournal_title
Endocrinologyauthors
Anderson MB,Sherwood ODdoi
10.1210/endo-114-4-1124subject
Has Abstractpub_date
1984-04-01 00:00:00pages
1124-7issue
4eissn
0013-7227issn
1945-7170journal_volume
114pub_type
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