Do young hepatocellular carcinoma patients with relatively good liver function have poorer outcomes than elderly patients?

abstract：BACKGROUND AND AIM:Hepatocellular carcinoma (HCC) is the third most common reason for cancer-related death worldwide. Many countries either lack appropriate clinical practice guidelines for the diagnosis and treatment of HCC or the quality of their guidelines has never been evaluated. The main objective of our work was...

journal_title：Journal of gastroenterology and hepatology

authors： Schmidt S,Follmann M,Malek N,Manns MP,Greten TF

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIM:Although several meta-analyses suggested that sequential therapy (SQT) is superior to standard triple therapy (STT) for the eradication of Helicobacter pylori, these results were mainly based on the studies from Italy. The aim of this study was to assess the efficacy of 10-day SQT for H. pylori infec...

journal_title：Journal of gastroenterology and hepatology

authors： Yoon H,Lee DH,Kim N,Park YS,Shin CM,Kang KK,Oh DH,Jang DK,Chung JW

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known about the role of hepatitis B virus (HBV) factors in the long-term prognosis of hepatocellular carcinoma (HCC) after resection. The objective of the present study was to identify the changing patterns of HBV levels and its effect on outcome after resection. METHODS:This study recruit...

journal_title：Journal of gastroenterology and hepatology

authors： An HJ,Jang JW,Bae SH,Choi JY,Cho SH,Yoon SK,Han JY,Lee KH,Kim DG,Jung ES

更新日期：2010-12-01 00:00:00

abstract：:A frequent association of biliary tract carcinoma and anomalous pancreaticobiliary ductal union (APBD) is well recognized, especially gall-bladder carcinoma in undilated type APBD. However, little is known about the presence and incidence of adenomyomatosis (AMT) of the gall-bladder, a presumed premalignant lesion, in...

journal_title：Journal of gastroenterology and hepatology

authors： Tanno S,Obara T,Maguchi H,Fujii T,Mizukami Y,Shudo R,Takahashi K,Nishino N,Arisato S,Ura H,Kohgo Y

更新日期：1998-02-01 00:00:00

abstract：:Antipyrine metabolism is widely used as an index of the drug-metabolizing reserve of the liver. It is well known that metabolism of this drug is impaired in subjects with acute hepatitis or cirrhosis, but conflicting data have been reported regarding patients with chronic postinfectious hepatitis or liver cancer. We s...

journal_title：Journal of gastroenterology and hepatology

authors： Grieco A,Castellano R,Matera A,Marcoccia S,Di Rocco P,Ragazzoni E,Vecchio FM,Gasbarrini G

更新日期：1998-05-01 00:00:00

abstract：:A novel experimental model of submassive liver necrosis with impaired regeneration has been established. A novel lipid A analogue, FS-112, was injected intravenously into male BALB/c mice, followed 2 days later by a 70% partial hepatectomy. Over the next 9 days, mice became severely jaundiced, with a peak total biliru...

journal_title：Journal of gastroenterology and hepatology

authors： Maeda T,Ohnishi H,Hayashi T,Ishiki Y,Moriwaki H,Muto Y

更新日期：1996-05-01 00:00:00

abstract：:AL amyloidosis complicating multiple myeloma is rare but well recognized. Endoscopic appearances of amyloid in the gastrointestinal tract can, however, be highly variable. Macroscopic appearances of the duodenum can range from scalloping (often seen in celiac disease) to that of duodenitis; erosive disease, frank ulce...

journal_title：Journal of gastroenterology and hepatology

authors： Hurlstone DP

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND AIM:Pancreatic pseudocyst is a common complication of chronic pancreatitis. The identification of risk factors and development of a nomogram for pancreatic pseudocysts in chronic pancreatitis patients may contribute to the early diagnosis and intervention of pancreatic pseudocysts. METHODS:Patients with...

journal_title：Journal of gastroenterology and hepatology

authors： Hao L,Pan J,Wang D,Bi YW,Ji JT,Xin L,Liao Z,Du TT,Lin JH,Zhang D,Zeng XP,Ye B,Zou WB,Chen H,Xie T,Li BR,Zheng ZH,Hu LH,Li ZS

更新日期：2017-07-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) was previously thought to be rare in Asia, but emerging data indicate rising incidence and prevalence of IBD in the region. The Asia Pacific Working Group on Inflammatory Bowel Disease was established in Cebu, Philippines, at the Asia Pacific Digestive Week conference in 2006 under the...

journal_title：Journal of gastroenterology and hepatology

authors： Ooi CJ,Makharia GK,Hilmi I,Gibson PR,Fock KM,Ahuja V,Ling KL,Lim WC,Thia KT,Wei SC,Leung WK,Koh PK,Gearry RB,Goh KL,Ouyang Q,Sollano J,Manatsathit S,de Silva HJ,Rerknimitr R,Pisespongsa P,Abu Hassan MR,Sung J,

更新日期：2016-01-01 00:00:00

abstract：:Despite a high prevalence of liver disease in Viet Nam, there has been no nationwide approach to the disease and no systematic screening of at-risk individuals. Risk factors include chronic hepatitis B (estimated prevalence of 12%), chronic hepatitis C (at least 2% prevalence), and heavy consumption of alcohol among m...

journal_title：Journal of gastroenterology and hepatology

authors： Gish RG,Bui TD,Nguyen CT,Nguyen DT,Tran HV,Tran DM,Trinh HN,International Group for Liver Health in Viet Nam.

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Sepsis is an important complication and cause of morbidity and mortality in acute pancreatitis (AP). The source of sepsis may be infected pancreatic and peripancreatic collections and/or necrosis or extrapancreatic including infections in the bloodstream or respiratory and urinary tracts. We studied...

journal_title：Journal of gastroenterology and hepatology

authors： Rao C,Bhasin DK,Rana SS,Gupta R,Gautam V,Singh K

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the potential role of three-dimensional (3-D) conformal radiotherapy (RT) in treatment of unresectable hepatocellular carcinoma (HCC). METHODS:Thirteen patients were included in this study, which was conducted between 1993 and 1996. Nine patients (group A) were tre...

journal_title：Journal of gastroenterology and hepatology

authors： Cheng SH,Lin YM,Chuang VP,Yang PS,Cheng JC,Huang AT,Sung JL

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND AIM:A novel virus, SEN-virus (SENV), was recently discovered. It has been reported as a candidate for a non-A-E hepatitis virus. However, much is still unknown about the clinical significance of SENV. The aim of the present study was to clarify the clinical significance of SENV in patients coinfected wit...

journal_title：Journal of gastroenterology and hepatology

authors： Lin JG,Goto T,Nakane K,Miura K,Mikami K,Ohshima S,Yoneyama K,Watanabe S

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND AIM:We assessed whether the two regimens of pegylated alpha-interferon-2b (PEG-IFN-alpha2b) plus ribavirin and pegylated alpha-interferon-2a (PEG-IFN-alpha2a) plus ribavirin showed differences in terms of sustained virological response, withdrawal due to side-effects and dose adjustment requirements in t...

journal_title：Journal of gastroenterology and hepatology

authors： Escudero A,Rodríguez F,Serra MA,Del Olmo JA,Montes F,Rodrigo JM

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND AIM:The risk for erosive esophagitis (EE) with low-dose aspirin (ASA) remains unknown, especially among Japanese patients. We conducted the present study to compare the risk of EE with that of gastroduodenal mucosal injury among Japanese patients taking ASA. METHODS:From 5555 patients undergoing upper g...

journal_title：Journal of gastroenterology and hepatology

authors： Yamamoto T,Mishina Y,Ebato T,Isono A,Abe K,Hattori K,Ishii T,Kuyama Y

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND AIM:Single-nucleotide polymorphisms (SNPs) in long non-coding RNAs (lncRNAs) are potential biomarkers for cancer risk, but their association with hepatocellular carcinoma (HCC) is unclear. We examined the association of lncRNA-related SNPs with HCC susceptibility and explored the optimal genetic models f...

journal_title：Journal of gastroenterology and hepatology

authors： Li Y,He HC,Zhou DL,Liu Q,Zhang X,Yang XH,Ye ZL,Peng JL,Tang T,Su X,He CY

更新日期：2021-01-01 00:00:00

abstract：:There are approximately 277,000 new cases of pancreatic cancer and 266,000 deaths from pancreatic cancer annually, indicating a mortality rate of 96% of the cases diagnosed. Because of the ineffectiveness of therapies, a major emphasis needs to be placed on prevention. This paper reviews the epidemiology and risk fact...

journal_title：Journal of gastroenterology and hepatology

authors： Pandol S,Gukovskaya A,Edderkaoui M,Dawson D,Eibl G,Lugea A

更新日期：2012-03-01 00:00:00

abstract：:Primary liver cancer, particularly hepatocellular carcinoma (HCC) remains a significant disease worldwide. It is among the top three causes of cancer death in the Asia Pacific region because of the high prevalence of its main etiological agents, chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. I...

journal_title：Journal of gastroenterology and hepatology

authors： Yuen MF,Hou JL,Chutaputti A,Asia Pacific Working Party on Prevention of Hepatocellular Carcinoma.

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Serum alanine aminotransferase (ALT) is commonly used to detect liver damage. Recent studies indicate that ALT levels at the upper range of normal limits are predictors of adverse outcomes, especially diabetes mellitus (DM) and the metabolic syndrome. The aim of our study was to define the ALT thres...

journal_title：Journal of gastroenterology and hepatology

authors： Shlomai A,Kariv R,Leshno M,Beth-or A,Sheinberg B,Halpern Z

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND AIM:The conventional method of anatomical right hemihepatectomy (ARHH) requires hilus dissection. We report a method without hilus dissection to minimize intraoperative bleeding. METHODS:We retrospectively evaluated data of 107 patients who received ARHH involving ligation of corresponding inflow and ou...

journal_title：Journal of gastroenterology and hepatology

authors： Chen XP,Zhang ZW,Huang ZY,Chen YF,Zhang WG,Qiu FZ

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND AIM:Increased production of reactive oxygen species, which cause oxidative DNA damage, is considered to be related to hepatocarcinogenesis. 8-Hydroxy-2'-deoxy-guanosine (8-OHdG) is a useful marker of DNA damage induced by oxidative stress. The aim of this study was to determine whether expression of 8-OH...

journal_title：Journal of gastroenterology and hepatology

authors： Chuma M,Hige S,Nakanishi M,Ogawa K,Natsuizaka M,Yamamoto Y,Asaka M

更新日期：2008-09-01 00:00:00

abstract：:Patients with Crohn's disease of the distal ileum show increased permeability to hyaluronan and increased release of histamine and complement components in uninvolved parts of the proximal jejunum. These abnormalities are related to disease activity, and are not found in first-degree relatives. Increased synthesis of ...

journal_title：Journal of gastroenterology and hepatology

authors： Ahrenstedt O,Hällgren R,Knutson L

更新日期：1994-11-01 00:00:00

abstract：:Gastrointestinal (GI) manifestations of leukemia occur in up to 25% of patients at autopsy, generally during relapse. Its presence varies with the type of leukemia and has been decreasing over time due to improved chemotherapy. Gross leukemic lesions are most common in the stomach, ileum, and proximal colon. Leukemia ...

journal_title：Journal of gastroenterology and hepatology

authors： Ebert EC,Hagspiel KD

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis C virus (HCV)-infected patients who responded to interferon (IFN) treatment with clearance of serum HCV RNA may rarely develop hepatocellular carcinoma (HCC). The aim of the present study was to elucidate the risk factors for liver carcinogenesis among such patients. METHODS:In total, 126 ...

journal_title：Journal of gastroenterology and hepatology

authors： Tokita H,Fukui H,Tanaka A,Kamitsukasa H,Yagura M,Harada H,Okamoto H

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND AIM:The present study was designed to investigate the expression of and humoral response against NY-ESO-1 in patients with hepatocellular carcinoma and to analyze the relationship between expression of NY-ESO-1 mRNA and clinicopathological features. METHODS:NY-ESO-1 mRNA and protein expression in surgic...

journal_title：Journal of gastroenterology and hepatology

authors： Nakamura S,Nouso K,Noguchi Y,Higashi T,Ono T,Jungbluth A,Chen YT,Old LJ,Nakayama E,Shiratori Y

更新日期：2006-08-01 00:00:00

abstract：AIM:The clinical presentation of four children and adolescents (two males and two females with a mean age of 12.4 years; range 9-16 years) with colorectal spirochetosis is discussed. RESULTS:Symptoms included persistent diarrhea (n = 2), rectal bleeding (n = 1) and abdominal pain (n = 2). In all patients, colorectal s...

journal_title：Journal of gastroenterology and hepatology

authors： Heine RG,Ward PB,Mikosza AS,Bennett-Wood V,Robins-Browne RM,Hampson DJ

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Depth of invasion beyond the muscularis propria (MP) by T3 rectal cancer can vary. The purpose of the present paper was to determine if depth of invasion beyond MP, as assessed by preoperative endoscopic ultrasound (EUS), can predict tumor recurrence in patients with T3 rectal tumors. METHODS:Patients with ...

journal_title：Journal of gastroenterology and hepatology

authors： Harewood GC,Kumar KS,Clain JE,Levy MJ,Nelson H

更新日期：2004-07-01 00:00:00

abstract：AIM:To determine the inter-observer agreement and validity of the LA Classification in scoring the severity of esophagitis in Asian patients. METHODS:Video endoscopy clips were selected from 45 consecutive patients participating in reflux studies. The videos were viewed by endoscopists who then independently scored th...

journal_title：Journal of gastroenterology and hepatology

authors： Wong RK,Yeoh KG,Gwee KA,Tay HW,Ho KY

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Nicotine administration is known to decrease lower oesophageal sphincter (LOS) pressure. Although a few studies have assessed the effect of tobacco on the LOS, the effect of acute and long-term oral tobacco use on oesophageal motility is not known. The study was designed to investigate the effect of...

journal_title：Journal of gastroenterology and hepatology

authors： Bhandarkar PV,Shah SK,Meshram M,Abraham P,Narayanan TS,Bhatia SJ

更新日期：2000-09-01 00:00:00