Abstract:
:There is renewed interest in the classification and methods of recording adventitious pulmonary sounds. This is a study of the importance of fine crackles (rales) in the diagnosis and estimation of the severity of diffuse infiltrative pulmonary disease. Among 272 cases documented by lung biopsy, bilateral fine crackles were heard in 60 percent of those with interstitial pneumonias and asbestosis but in only 20 percent of those with sarcoidosis and other granulomatoses. These incidences were identical in 335 patients diagnosed clinically. In 322 selected ambulatory patients with chronic obstructive pulmonary disease, fine crackles were recorded in only 10 to 12 percent, while coarse crackles were not uncommon in patients with chronic bronchitis. In workers exposed to asbestos, crackles correlated with exposure. In serial studies of such workers, the occurrence of crackles alone appeared to be a random event, while among those with crackles together with one other of five criteria, almost one-half developed asbestosis within four to six years. Fine crackles correlated with pathologic severity, with radiographic honeycombing, and with physiologic abnormalities.
journal_name
Chestjournal_title
Chestauthors
Epler GR,Carrington CB,Gaensler EAdoi
10.1378/chest.73.3.333subject
Has Abstractpub_date
1978-03-01 00:00:00pages
333-9issue
3eissn
0012-3692issn
1931-3543pii
S0012-3692(16)38043-6journal_volume
73pub_type
杂志文章相关文献
CHEST文献大全abstract:STUDY OBJECTIVES:To assess the effectiveness of pulse oximetry and radioisotope measurement of right-to-left (R-L) shunt for the early detection of pulmonary arteriovenous malformations (PAVMs) in patients with hereditary hemorrhagic telangiectasia (HHT). DESIGN:Patients with HHT had serial measurements of the followi...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.115.1.109
更新日期:1999-01-01 00:00:00
abstract::A 21-year follow-up after tricuspid valve replacement (TVR) with a Starr-Edwards caged-ball prosthesis in a ten-year old boy is described. TVR is performed for Ebstein's anomaly, with strict indications in childhood. Despite the current preference for bioprostheses, good performance can be expected from the Starr-Edwa...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.94.5.1096
更新日期:1988-11-01 00:00:00
abstract::The therapeutic effects of cuirass ventilation were studied in two patients with bilateral diaphragm paralysis. Negative inspiratory and positive expiratory pressure applied to the cuirass shell was transmitted to the abdominal and thoracic cavities. Diaphragm excursion was enhanced. Nocturnal cuirass ventilation appe...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.92.4.683
更新日期:1987-10-01 00:00:00
abstract::Two rules of good graphs are presented and explicated. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.130.2.620
更新日期:2006-08-01 00:00:00
abstract::We report two cases of pneumothorax detected by echographic examination immediately after ultrasonically guided aspiration biopsy and confirmed by chest x-ray film. The pneumothorax was characterized by the disappearance of the lung tumor. In the real-time image, the respiratory excursions of the visceral pleura also ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.101.3.855
更新日期:1992-03-01 00:00:00
abstract::The determination of effective dynamic and static relationships between pressure and volume aided in the diagnosis of pulmonary disease, its course, and the effects of therapy in 22 patients receiving continuous mechanical ventilation. These measurements were made on multiple occasions early in the course of mechanica...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.70.6.740
更新日期:1976-12-01 00:00:00
abstract:BACKGROUND:Airway inflammation is important in the development and progression of asthma. Activation of inflammatory cells induces a respiratory burst resulting in the production of reactive oxygen species, such as H(2)O(2). The aim of this study was to measure the concentration of H(2)O(2) in exhaled breath condensate...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.4.1136
更新日期:2001-10-01 00:00:00
abstract::To evaluate the role of inhaled ipratropium bromide in acute asthma, a double-blind study of 384 emergency department patients compared the effect of the combination of ipratropium and albuterol with that of albuterol alone. Patients were randomized to receive nebulizer treatments with either 2.5 mg of albuterol or 2....
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1378/chest.110.3.611
更新日期:1996-09-01 00:00:00
abstract::Congenital diaphragmatic hernia (CDH) is associated with a variety of cardiac anomalies. However, its association with hypoplastic left heart syndrome (HLHS) is rare. We treated a female newborn with CDH, HLHS, and omphalocele. The operation for omphalocele and the diaphragmatic defect was successful, although the pat...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.101.1.263
更新日期:1992-01-01 00:00:00
abstract::To study the effects of upper mantle radiation therapy on pulmonary function, forced expiratory volume in one second (FEV1), vital capacity (VC), inspiratory capacity (IC), diffusing capacity for CO (DLCO) and diffusion per unit of alveolar volume (DL/VA were determined in 28 patients with Hodgkin's disease, stages 1-...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.75.6.688
更新日期:1979-06-01 00:00:00
abstract::This study was undertaken to determine if the production of pulsatile flow by the intra-aortic balloon pump during cardiopulmonary bypass has any beneficial effect on coronary flow, regional myocardial flow, myocardial metabolism, and left ventricular function. Thirty-six conditioned dogs were subjected to one hour of...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.75.1.37
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND:Tranexamic acid (TA) is an antifibrinolytic drug currently used systemically to control bleeding. To date, there have been no prospective studies of the effectiveness of inhaled TA for the treatment of hemoptysis. OBJECTIVES:The goal of this study was to prospectively assess the effectiveness of TA inhalati...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.chest.2018.09.026
更新日期:2018-12-01 00:00:00
abstract::In two patients a documented Texas A2 influenza infection was associated with the development of interstitial pulmonary disease. One patient had an acute fulminating process resulting in respiratory failure and necessitating ventilatory assistance. Open lung biopsy revealed a histologic picture consistent with usual i...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.80.2.123
更新日期:1981-08-01 00:00:00
abstract:OBJECTIVE:To determine the success rate and correlates of ambulatory peak expiratory flow (PEF) monitoring in an epidemiologic study. DESIGN:An observational survey. SETTING:Several communities in California. PARTICIPANTS:We studied 1,223 nonsmoking men and women (mean age, 66 years) from an established cohort. OUT...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.112.4.895
更新日期:1997-10-01 00:00:00
abstract::Because of its greater ease and rapidity of insertion, the percutaneous intraaortic balloon in many institutions has become the primary method for implementing counterpulsation. We report the results and complications of 113 attempted procedures in a variety of clinical settings. We had a high (93.8 percent) insertion...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.82.4.422
更新日期:1982-10-01 00:00:00
abstract::Postinfluenza toxic shock syndrome is a recently described entity that results from a respiratory tract infection with toxin-producing Staphylococcus aureus following an episode of influenza or influenzalike illness. This report describes a 19-year-old man who developed an influenza B respiratory infection complicated...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.95.5.1153
更新日期:1989-05-01 00:00:00
abstract:UNLABELLED:Protected specimen brush (PSB) is considered to be one of the standard methods for the diagnosis of ventilator-associated pneumonia, but to our knowledge, intraindividual variability in results has not been reported previously. PURPOSE:To compare the results of two PSB performed in the same subsegment on pa...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.104.1.104
更新日期:1993-07-01 00:00:00
abstract::Hydrochlorothiazide (HCTZ)-induced pulmonary disease has been described as either an allergic interstitial pneumonitis or a cause of noncardiogenic pulmonary edema. The mechanism of this rare life-threatening side effect is largely unknown. Many patients show peripheral leukopenia and extensive immunologic studies rev...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-0944
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Habitual smoking of alkaloidal cocaine (crack) has been reported to be associated with a number of cardiopulmonary complications that may not be clinically obvious but could potentially interfere with normal physiologic responses to exercise and thus impair maximum exercise performance. STUDY OBJECTIVE:To e...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.112.4.1008
更新日期:1997-10-01 00:00:00
abstract::Epidemiologic research has revealed a substantial portion of the general population with abnormal spirometry results that are characterized by decreased FEV1 and FVC but a preserved FEV1/FVC ratio. This restrictive spirometry pattern (RSP) is inconsistently defined in the literature and not well addressed by current g...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.15-1045
更新日期:2016-01-01 00:00:00
abstract::Acute hypoxemia produces opposite effects on the pulmonary and systemic vascular resistance. To assess the influence of acute hypoxemia on cardiac murmurs, 36 patients with a single valvular or congenital heart lesion were studied. As expected from these hemodynamic effects, right-sided regurgitant type murmurs increa...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.81.2.159
更新日期:1982-02-01 00:00:00
abstract::We treated five patients with a past history of tuberculous pleural infection that led to chronic, quiescent, loculated empyema. Reactivation of TB was associated with formation of BPF and recovery of drug-susceptible Mycobacterium tuberculosis from sputum. All patients had recurrence of positive sputum cultures that ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.100.1.124
更新日期:1991-07-01 00:00:00
abstract:STUDY OBJECTIVES:We sought to determine the indicators of asthma severity among children in the United States with high and low levels of tobacco smoke exposure. DESIGN:Cross-sectional study. SETTING:Nationally representative survey of participants in the Third National Health and Nutrition Examination Survey (from 1...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.122.2.409
更新日期:2002-08-01 00:00:00
abstract::There has been dramatic resurgence of interest in surgical treatment of emphysema, particularly "lung volume reduction" procedures. Recent studies have demonstrated improvements in pulmonary function, lung mechanics, exercise tolerance, and quality of life in selected patients following volume reduction procedures. Ho...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.110.1.205
更新日期:1996-07-01 00:00:00
abstract::Respondents at an interactive symposium on pleural space infections (n = 339) at the 1991 American College of Chest Physicians Annual Scientific Assembly recorded their personal management preferences for hypothetical patients with empyema. The group's preference was to treat pleural sepsis from an anaerobic multilocu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.1.259
更新日期:1993-01-01 00:00:00
abstract::Systemic air embolism is a rare but potentially fatal complication of percutaneous transthoracic needle biopsy of the lung. Coronary air embolism can result in myocardial infarction, cardiac arrest, or dysrhythmias. We present the first case of cardiac arrest and myocardial infarction confirmed by ECG and cardiac enzy...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.121.3.993
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:In adult patients, the consistent use of language to describe dyspnea enhances patient-provider communication and contributes to diagnostic and therapeutic decisions. The objective of this research was to determine whether pediatric patients similarly display consistency in the language used to describe "unc...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-2388
更新日期:2011-04-01 00:00:00
abstract::On the occasion of this Fourth World Conference on Lung Cancer, I am privileged to present the opening keynote address. This presentation has been sponsored by the Ontario Cancer Treatment and Research Foundation. In 1952, the Foundation established an annual lectureship in memory of one of their prominent physicians....
journal_title:Chest
pub_type: 临床试验,历史文章,杂志文章,评审
doi:10.1378/chest.89.4.200s
更新日期:1986-04-01 00:00:00
abstract:BACKGROUND:The long-term clinical course of asthma in patients with eosinophilic granulomatosis with polyangiitis (EGPA) remains unclear. We aimed to characterize long-term asthma in EGPA and to identify baseline predictors of long-term asthma severity. METHODS:This retrospective cohort study included patients who ful...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2019.11.045
更新日期:2020-05-01 00:00:00
abstract::There is heightened concern that older adults and individuals with occult or known heart disease are exercising at fitness facilities that do not provide adequate cardiovascular screening and emergency procedures, as outlined in contemporary recommendations. To evaluate adherence to these standards, we surveyed 122 ra...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.1.283
更新日期:2001-07-01 00:00:00