Reserpine and breast cancer.

Abstract:

:After a series of studies on the linkage of reserpine with breast cancer, both evidence and interpretation appeared to be in conflict. Our case-control survey of long-term, comprehensive records from the Kaiser Foundation Medical Care Program, on 108 hypertensive breast cancer cases and 324 hypertensive controls, matched by year of birth and by race, produces a significant positive association between reserpine use and breast cancer. However, the association vanishes upon further matching with respect to the year of the first hypertension diagnosis and the subsequent length of follow-up. We thus fail to support suspicions of causality.

journal_name

Cancer

journal_title

Cancer

authors

Kodlin D,McCarthy N

doi

10.1002/1097-0142(197802)41:2<761::aid-cncr2820410

subject

Has Abstract

pub_date

1978-02-01 00:00:00

pages

761-8

issue

2

eissn

0008-543X

issn

1097-0142

journal_volume

41

pub_type

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