Abstract：
:The immunological activity in the cerebrospinal fluid (CSF) was studied in 47 patients with early syphilis. The immunoglobulin production within the central nervous system (CNS) was estimated by analysing immunoglobulin G and albumin in CSF and serum and constructing an IgG index according to Tibbling et al. and calculating daily CNS IgG synthesis, according to Tourtellotte. In 10 (21%) of the 47 patients, intrathecal immunoglobulin production was observed. The immunoglobulin production within the CNS was significantly correlated to the presence of syphilis antibodies and to pleocytosis. Eight of the patients demonstrated oligoclonal bands on electrophoresis. Total protein usually did not reveal an increased CNS immunoglobulin production but reflected a blood-brain barrier lesion. One year after penicillin treatment, 2 out of 9 patients still had slight intrathecal immunoglobulin production.
journal_name
Acta Derm Venereoljournal_title
Acta dermato-venereologicaauthors
Löwhagen GB,Andersson M,Blomstrand C,Roupe Gsubject
Has Abstractpub_date
1983-01-01 00:00:00pages
409-17issue
5eissn
0001-5555issn
1651-2057journal_volume
63pub_type
杂志文章abstract：:The role of cell-mediated immunity in controlling Basal Cell Carcinoma (BCC) growth was studied by measuring the transformation of lymphocytes when challenged in vitro with aqueous extracts of the patients' BCCs and of control skin. Tests were carried out in the presence of autologous and heat-treated plasma. Three pa...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:Eighty-two cases of nodular panniculitis of the legs were examined clinically, histologically and immunohistologically. Clinically the cases could be divided into four groups: typical erythema nodosum (ENty) (35 cases), erythema nodosum migrans (ENmi) (11 cases), erythema induratum (EI) (11 cases) and the remaining 25...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Biopsies for electron microscopy were obtained from syphilitic chancres of 7 patients, 6 males and one female. In 4 of the patients, Treponemata pallida were seen gathering around peripheral nerves and invading the spaces between Schwann cells and their basal lamina. No definite degenerative changes were seen in the a...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:We report a 69-year-old man with severe generalized morphea, who showed over 80% of skin involvement, while the internal organs were not affected. We performed histological examinations and analysis of skin disaccharides constituting chondroitinase-digestible glycosaminoglycans in the center and periphery of the scler...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555576141143
更新日期：1996-03-01 00:00:00
abstract：:Although mosquito allergy induces the release of histamine, the itch-related response, scratching, is not effectively suppressed by blockade of H1 histamine receptors. To address this question, we examined the effects of neonatal capsaicin treatment on allergic reactions and H1 histamine receptor-expressing sensory ne...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-0479
更新日期：2008-01-01 00:00:00
abstract：:BRAF and NRAS genetic analyses are time-consuming and can delay treatment choices in patients with metastatic melanomas presenting with acute deterioration. We compared the rapid, real-time, fully automated molecular diagnosis platform Idylla™ with next-generation sequencing (NGS) and immunohistochemistry for detectio...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-2738
更新日期：2018-01-12 00:00:00
abstract：:The hypothesis that zinc pyrithione, a highly active anti-dandruff agent, exerts an anti-biosynthetic effect and reduces the epidermal turnover has been tested using guinea pig and hairless mouse skins. It has been found that enhanced mitosis caused by both stripping off the horny layers and sodium dodecyl sulphate, c...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:We set out to show that the assumption is incorrect that continuous treatment with cyclosporin is necessary in psoriasis, as this tenet forms a basis for current recommended treatment regimens. Sixty patients with mild to moderate plaque psoriasis were allocated at random to treatment with oral cyclosporin 5 mg/kg/day...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.2340/00015555756569
更新日期：1995-01-01 00:00:00
abstract：:ESR spectra of synthetic melanins formed from dopa and from 5-S-cysteinyldopa and of melanins isolated from human melanomas were studied. Alkali-soluble melanin synthesized from cysteinyldopa showed a signal similar to that of insoluble melanin synthesized from dopa, but also a simple fine structure. Trichochromes C a...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:Health-related quality of life (HRQOL) has become an important patient reported outcome in health service research. The dermatology life quality index (DLQI) is the most commonly used instrument in dermatology. In recent years, the psychometric properties of the DLQI have been a subject of debate as requirements of mo...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-1842
更新日期：2014-11-01 00:00:00
abstract：:Skin biopsies from a collodion baby, spontaneously healing at the end of the third month, were taken on the 1st and 15th day after delivery and examined by light and electron microscopy. The microscopical features observed were different from those known to occur in collodion babies evolving into lamellar ichthyosis a...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:The combination of hydroxyzine and cimetidine is reported to be more effective than hydroxyzine alone in chronic urticaria. The plasma concentration of hydroxyzine was studied in seven patients treated both with the hydroxyzine 25 mg t.i.d. and the combinations of hydroxyzine 25 mg and cimetidine 200 mg t.i.d. Hydroxy...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:We evaluated the effect of acupuncture on histamine-induced itch and flare in healthy volunteers (n = 25) and compared it with the effect of a pseudo-acupuncture procedure and of no-intervention in a single-blind randomized cross-over study. A cumulative itch index is defined and was found to be smaller with acupunctu...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1984-01-01 00:00:00
abstract：:In a randomized, controlled parallel group study we have shown that cyclosporine at 3 mg/kg/day is as effective as topical betamethasone-17,21-dipropionate in the treatment of chronic hand eczema. In this study we compared the influence of these therapies on the quality of life. Forty-one patients were treated with ei...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.2340/00015555775458
更新日期：1997-01-01 00:00:00
abstract：:The pathogenesis of seborrhoeic dermatitis is controversial and remains unclear. Malassezia is considered to be a commensal fungi and is found not only in the stratum corneum but also in hair follicles. It is an important pathogenic factor in seborrhoeic dermatitis. The aim of this study was to clarify the pathogenesi...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-3519
更新日期：2020-06-15 00:00:00
abstract：:Stratum corneum chymotryptic enzyme (SCCE) may be involved in desquamation, a process necessary for maintaining a normal anatomy at all sites where there is continuous turnover of cornified epithelia. Using immunohistochemistry and in situ hybridization, we have, in this work, analysed SCCE expression in the sebaceous...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155598443015
更新日期：1998-09-01 00:00:00
abstract：:Although palmoplantar psoriasis can be severely disabling, there are very few large clinico-epidemiological studies on this condition. Our purpose was to study the morphology and pattern of lesions in Indian patients with palmoplantar psoriasis and to elucidate the role of occupation in the incidence/localization of t...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/00015550260132488
更新日期：2002-01-01 00:00:00
abstract：:The aims of this study were to compare the performance characteristics and cost-effectiveness of pooling endocervical samples for screening and diagnosis of Chlamydia trachomatis, and to investigate the prevalence of C. trachomatis infection in women in Leningrad Oblast, Russia. A total of 1500 endocervical samples we...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-0196
更新日期：2007-01-01 00:00:00
abstract：:Abnormal expression of cell adhesion molecules and related proteins has been observed in various carcinoma cells. We compared expression patterns of desmosomal cadherins, E-cadherin, and cytoplasmic plaque proteins of four different human squamous cell carcinoma cell lines and in vivo squamous cell carcinoma cells wit...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/0001555576417420
更新日期：1996-11-01 00:00:00
abstract：:The WR, Kline and VDRL reactions were compared in 496 cases of syphilis. The VDRL was significantly more sensitive than both WR and Kline. ...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Oxidation of 5-S-cysteinyldopa by mushroom tyrosinase was studied by measuring 5-S-cysteinyldopa consumption with HPLC. 5-S-cysteinyldopa was found to be a substrate for tyrosinase, but our results suggests that a self-catalysed oxidation induced by enzymatically formed 5-S-cysteinyl dopaquinone also takes place. Dopa...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:The close chromosomal proximity of major histocompatibility complex and tumour necrosis factor genes may suggest the involvement of the latter in the pathogenesis of immunological diseases associated with HLA antigenes. The major histocompatibility complex antigens may play a certain role in the pathogenesis of lichen...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/00015550510037053
更新日期：2005-01-01 00:00:00
abstract：:Although recent therapeutic developments raise hope, melanoma remains a devastating disease with a need for new treatment targets. In other tumours prohormone convertases have been shown to be pro-tumourigenic as they are involved in processing preforms of matrix-metalloproteinases, growth factors and adhesion molecul...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-3525
更新日期：2020-05-28 00:00:00
abstract：:Pigmented basal cell carcinomas can be difficult to distinguish clinically from melanoma. Dermoscopy has proven to be useful in the differential diagnosis of the two tumour types. SIAscopy (Spectrophotometric intracutaneous analysis) is a fairly new technique of imaging pigmented skin lesions that has been presented p...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-0234
更新日期：2007-01-01 00:00:00
abstract：:Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of end-stage liver disease. The aim of this controlled cross-sectional study was to assess the association between NAFLD and hidradenitis suppurativa. NAFLD was assessed using hepatic ultrasound. A total of 125 patients with hidradenitis supp...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-3597
更新日期：2020-08-18 00:00:00
abstract：:Psoriasis has major physical, psychological, and social impacts: its management should not be restricted by individual financial considerations in Western countries as these have well-structured health systems and social/insurance coverage. We investigated if the socioeconomic characteristics of patients were associat...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章,多中心研究
doi：10.2340/00015555-2625
更新日期：2017-05-08 00:00:00
abstract：:Patients with latent syphilis or syphilis of unknown duration should be evaluated for tertiary disease and neurosyphilis. The aim of this retrospective study was to determine relevant serological parameters for the identification of those individuals with syphilis who are most likely to have neurosyphilis and who ther...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.2340/00015555-0092
更新日期：2006-01-01 00:00:00
abstract：:The initiation of the antihistamine effect of a single dose of acrivastine (8 mg) or cetirizine (10 mg) on wheals and itch induced by histamine dihydrochloride (10 mg/ml) in the prick test was studied in a randomized cross-over design employing 20 healthy medical students. The prick test was performed before ingestion...
journal_title：Acta dermato-venereologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.2340/0001555573350351
更新日期：1993-10-01 00:00:00
abstract：:An E.M. study was carried out to investigate whether Mycobacterium leprae occur intracellularly in epidermal melanocytes. As this could not be confirmed, the selective killing of melanocytes by cytotoxic lymphocytes could not explain the hypopigmentation in types of leprosy with a relative good immune response. There...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Previous studies have shown that magnetic resonance imaging is more sensitive in assessing soft tissue and bone involvement in inflammatory arthritis than conventional radiography. Therefore the main objects of this study were to evaluate the frequency of hand involvement in psoriatic patients free from arthritic symp...
journal_title：Acta dermato-venereologica
pub_type： 杂志文章
doi：10.1080/000155598442809
更新日期：1998-11-01 00:00:00
