Initiation of the effects of acrivastine and cetirizine on histamine-induced wheals and itch in human skin.

Abstract:

:The initiation of the antihistamine effect of a single dose of acrivastine (8 mg) or cetirizine (10 mg) on wheals and itch induced by histamine dihydrochloride (10 mg/ml) in the prick test was studied in a randomized cross-over design employing 20 healthy medical students. The prick test was performed before ingestion of the drug and after 15, 20, 25, 30, 60 and 90 min and 2, 3 and 4 h. Local symptoms (itching) were recorded on a visual analogue scale. The inhibitory effect of acrivastine on the histamine wheal was first noticed 20 min (p < 0.01) after ingestion of the drug and that of cetirizine after 60 min (p < 0.001). The maximum effect of cetirizine, at 4 h, was greater than that of acrivastine, at 3 h (p < 0.001). The suppression of itching was first noticed 25 min after ingestion with both drugs.

journal_name

Acta Derm Venereol

authors

Lahti A,Haapaniemi T

doi

10.2340/0001555573350351

subject

Has Abstract

pub_date

1993-10-01 00:00:00

pages

350-1

issue

5

eissn

0001-5555

issn

1651-2057

journal_volume

73

pub_type

临床试验,杂志文章,随机对照试验
  • Epidermodysplasia verruciformis. Skin carcinoma containing human papillomavirus type 5 DNA sequences and primary hepatocellular carcinoma associated with chronic hepatitis B virus infection in a patient.

    abstract::In a case of epidermodysplasia verruciformis with impaired cell-mediated immunity and multiple skin cancers human papillomavirus type 5 (HPV5) DNA sequences were demonstrated in a cutaneous squamous cell carcinoma. HPV5 and HPV8 were detected in the benign disseminated skin lesions together with three newly characteri...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: van Voorst Vader PC,Orth G,Dutronquay V,Driessen LH,Eggink HF,Kallenberg CG,The TH

    更新日期:1986-01-01 00:00:00

  • Cutaneous paraneoplastic syndromes.

    abstract::A review of a variety of cutaneous paraneoplastic conditions is presented. Although the conditions discussed appear in only 7-15% of cancer patients, they are considered indicators of possible underlying malignancy. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,评审

    doi:10.2340/0001555573161170

    authors: Politi Y,Ophir J,Brenner S

    更新日期:1993-06-01 00:00:00

  • Nail--patella syndrome associated with renal failure requiring transplantation.

    abstract::The nail--patella syndrome is a rare, inheritable disease of the connective tissue in which multiple osseous abnormalities are associated with dysplasia of the nails. Renal dysfunction is found in 25--42% of cases and varies from asymptomatic proteinuria to renal failure. This paper describes a patient with nail--pate...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Verdich J

    更新日期:1980-01-01 00:00:00

  • Biogenic amines derived from tryptophan in systemic and cutaneous scleroderma.

    abstract::Blood levels of serotonin (5-HT) and urinary excretion of 5-hydroxyindole-acetic acid (5-HIAA), tryptamine (T), and indole-acetic acid (IAA) were determined in 39 cases of systemic scleroderma and in 7 cases of very severe cutaneous scleroderma. The T/IAA ratio was normal and serotonin elevated in mild and rather seve...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Stachów A,Jabłońska S,Skiendzielewska A

    更新日期:1979-01-01 00:00:00

  • Urinary glycosaminoglycans excretion in Graves' disease.

    abstract::Urinary excretion of glycosaminoglycans was measured in 10 patients with pretibial myxoedema, 7 of whom also had thyroid-associated ophthalmopathy, and in 3 additional patients with ophthalmopathy but no skin changes. Total uronic acid excretion was raised above control levels in only 2 patients, who had both eye and ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555576368370

    authors: Priestley GC,Aldridge RD,Hurel S

    更新日期:1996-09-01 00:00:00

  • Vascular Patterns in Cutaneous Ulcerated Basal Cell Carcinoma: A Retrospective Blinded Study Including Dermoscopy.

    abstract::The aim of this retrospective study was to determine the type and prevalence of vascular patterns in the ulcerated and non-ulcerated portions of histologically proven basal cell carcinomas (BCCs) and correlate them with other dermoscopic and clinical features, including the clinically supposed diagnosis. Three authors...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2609

    authors: Arpaia N,Filoni A,Bonamonte D,Giudice G,Fanelli M,Vestita M

    更新日期:2017-05-08 00:00:00

  • Transfer factor in mycosis fungoides: a case report on a patient "cured".

    abstract::A report is given of the successful treatment with transfer factor as an additional therapeutic agent of a patient in the tumour stage of mycosis fungoides who had not responded to conventional treatment with nitrogen mustard, methotrexate, or grenz rays alone. Besides twelve injections of transfer factor, the patient...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Zachariae H,Grunnet E,Thestrup-Pedersen K

    更新日期:1979-01-01 00:00:00

  • Finger skin perfusion pressure in generalized scleroderma.

    abstract::Skin perfusion pressure in fingers in 6 normal persons and 12 patients suffering from generalized scleroderma was estimated as the minimum external counterpressure required to stop 133Xenon wash-out. The isotope was introduced atraumatically into the skin, and local counter-pressure was exerted by a miniature blood pr...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Kristensen JK

    更新日期:1978-01-01 00:00:00

  • A Review of International Recommendations for the Diagnosis and Management of Chronic Urticaria.

    abstract::Both spontaneous and inducible forms of chronic urticaria pose a significant economic burden and have an adverse effect on patients' quality of life. The international guidelines and US practice parameters for the diagnosis and management of chronic urticaria both recommend performing a thorough patient history and ph...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,评审

    doi:10.2340/00015555-2496

    authors: Beck LA,Bernstein JA,Maurer M

    更新日期:2017-02-08 00:00:00

  • Analysis of the CDKN2A and CDK4 genes and HLA-DR and HLA-DQ alleles in two Spanish familial melanoma kindreds.

    abstract::Some confusion exists in the literature about which criteria should be used to define familial melanoma. This could explain the different reported frequencies of mutations in predisposing genes, mostly CDKN2A, in these patients. This study evaluated the human leucocyte antigen (HLA) class II genotype and the presence ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155500300012936

    authors: Nagore E,Climent J,Planelles MD,Ledesma E,Rubio-Moscardó F,Fortea JM,Oliver V

    更新日期:2000-11-01 00:00:00

  • Irritation and staining by dithranol (anthralin) and related compounds. III. Cumulative irritancy and staining during repeated chamber testing.

    abstract::Irritation and staining, the side effects of dithranol and related compounds have previously been studied after a single chamber-exposure. To mimic the therapeutic situation, the chamber application was repeated for 3 weeks on the uninvolved back skin of 17 psoriasis patients. In equimolar concentrations corresponding...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Brandt H,Mustakallio KK

    更新日期:1983-01-01 00:00:00

  • GM1-gangliosidosis type 1 involving the cutaneous vascular endothelial cells in a black infant with multiple ectopic Mongolian spots.

    abstract::GM1-gangliosidosis (GM1) is one of the metabolic storage diseases, of which a differential diagnosis requires an array of biochemical assays to determine the enzyme deficiency. This approach is not only time-consuming and costly but also unavailable to most hospital laboratories. However, a presumptive diagnosis of GM...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555573412415

    authors: Tang TT,Esterly NB,Lubinsky MS,Oechler HW,Harb JM,Franciosi RA

    更新日期:1993-12-01 00:00:00

  • Decreased lymphocyte aryl hydrocarbon hydroxylase and glutathione S-transferase activities in patients with hand dermatitis.

    abstract::Aryl hydrocarbon hydroxylase (AHH) and glutathione S-transferase (GST) (EC 2.5.1.18) activity were measured in human lymphocytes of peripheral blood from 8 patients with irritant or allergic contact dermatitis of the hands, and compared with data from a control group. Both AHH and GST activity was found to be signific...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Singh N,Hamann K,Clausen J

    更新日期:1982-01-01 00:00:00

  • Comparison of clinical and computerized image analyses in the assessment of skin ageing in smokers and non-smokers.

    abstract::Tobacco smoke and UV radiation are extrinsic risk factors for accelerated skin ageing. In this study the effects of smoking on wrinkling and ageing were assessed in males living in Northern Finland, where cumulative sun exposure is low. Smoking habits, age and facial wrinkling were estimated from facial photographs of...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550410014969

    authors: Raitio A,Kontinen J,Rasi M,Bloigu R,Röning J,Oikarinen A

    更新日期:2004-01-01 00:00:00

  • Comparative multi-center study with TRUE Test and Finn Chamber Patch Test methods in eight Swedish hospitals.

    abstract::292 individuals were patch tested with twelve allergens, using a new patch test technique, TRUE Test (TT). As controls, the same allergens in standard concentrations in petrolatum were applied using the Finn Chamber technique (FC). The allergen doses used in TT were chosen according to results from a previous serial d...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Ruhnek-Forsbeck M,Fischer T,Meding B,Pettersson L,Stenberg B,Strand A,Sundberg K,Svensson L,Wahlberg JE,Widström L

    更新日期:1988-01-01 00:00:00

  • Diffuse hair loss and psychiatric disturbance.

    abstract::32 women complaining of diffuse alopecia were assessed by a psychiatrist, and daily hair loss and root counts were measured and compared with control women. Seven of the 32 women had severe marital difficulties, and 2 of these were overtly depressed. In these 7 women, daily hair loss and telogen counts did not differ ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Eckert J

    更新日期:1975-01-01 00:00:00

  • Epidermal and urethroid penile cyst.

    abstract::The authors describe a 74-year-old man who presented with a 2-cm nodule on the ventral face of the penis, showing histologically a cyst lined by both epidermal and urethroid epithelium. The authors discuss the various histological forms of raphe median cysts of the penis. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Claudy AL,Dutoit M,Boucheron S

    更新日期:1991-01-01 00:00:00

  • Elastosis perforans serpiginosa with widespread arterial lesions: a case report.

    abstract::A case is presented of elastosis perforans serpiginosa (EPS) with unilateral dermal lesions, widespread arterial lesions with aortic rupture, and elastosis of the endocardium and bronchiolar walls. Other chronic skin disorders with lesions resembling EPS are discussed; and the arterial lesions compared with some arter...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Eide J

    更新日期:1977-01-01 00:00:00

  • In vivo and in vitro immune responses to trichophytin in dermatophytosis.

    abstract::Cell-mediated immunity in patients with verified dermatophytosis was investigated by means of skin test and lymphocyte stimulation test (LST) using purified trichophytin, prepared by the ethylene glycol method, and commercially available trichophytin. The purified trichophytin seemed to be more specific and sensitive ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Kaaman T,Petrini B,Wasserman J

    更新日期:1979-01-01 00:00:00

  • Unexpectedly high frequency of genital involvement in women with clinical and histological features of oral lichen planus.

    abstract::The main aims of this cross-sectional study were: (i) to assess the frequency of genital (vulval) lichen planus (VLP) and vulval lichen sclerosus (VLS) in women affected with oral lichen planus (OLP), regardless of the genital symptoms reported; and (ii) to verify whether any demographic, clinical, or histological fea...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0116

    authors: Di Fede O,Belfiore P,Cabibi D,De Cantis S,Maresi E,Kerr AR,Campisi G

    更新日期:2006-01-01 00:00:00

  • Rosacea: a cutaneous marker of Helicobacter pylori infection? Results of a pilot study.

    abstract::Given the long purported anecdotal association between rosacea and gastrointestinal disease, the discovery that Helicobacter pylori causes gastritis and duodenal ulcer disease has led to a hypothesized role for this organism in the aetiology of rosacea. We conducted a case-series study of 49 patients to assess the pot...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550310016544

    authors: Diaz C,O'Callaghan CJ,Khan A,Ilchyshyn A

    更新日期:2003-01-01 00:00:00

  • Neurosyphilis is unlikely in patients with late latent syphilis and a negative blood VDRL-test.

    abstract::Patients with latent syphilis or syphilis of unknown duration should be evaluated for tertiary disease and neurosyphilis. The aim of this retrospective study was to determine relevant serological parameters for the identification of those individuals with syphilis who are most likely to have neurosyphilis and who ther...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0092

    authors: Wöhrl S,Geusau A

    更新日期:2006-01-01 00:00:00

  • Analysis of high-dose intravenous immunoglobulin therapy in 16 patients with refractory autoimmune blistering skin disease: high efficacy and no serious adverse events.

    abstract::High-dose intravenous immunoglobulin (IVIG) therapy is used in patients with severe autoimmune blistering diseases that are refractory to standard immunosuppressive therapy. To determine the efficacy and frequency of adverse events of IVIG therapy, we retrospectively analysed data for 16 patients with pemphigus vulgar...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-1471

    authors: Seidling V,Hoffmann JH,Enk AH,Hadaschik EN

    更新日期:2013-05-01 00:00:00

  • Lower-limb Ulcers in Systemic Sclerosis: A Multicentre Retrospective Case-control Study.

    abstract::Lower-limb ulcers in systemic sclerosis patients are rarely reported. The aim of this study was to describe the main causes and outcomes of lower-limb ulcers in systemic sclerosis patients and to assess factors associated with ischaemic causes (arterial disease and/or microvascular impairment). A retrospective, multic...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,多中心研究

    doi:10.2340/00015555-2939

    authors: Bohelay G,Blaise S,Levy P,Claeys A,Baudot N,Cuny JF,Maillard H,Granel-Brocard F,Boyé T,Lok C,Bénéton N,Francès C,Senet P

    更新日期:2018-07-11 00:00:00

  • Recurrent leg ulcers in a young man with hyperhomocysteinemia, factor V Leiden and impaired fibrinolysis.

    abstract::We present a young male patient referred to our hospital with leg ulcers on both legs that were more than 3 years refractory to standard treatment with compression therapy. By thrombophilia screening factor V Leiden mutation, hyperhomocysteinemia and evidence for impaired fibrinolysis were found. Treatment with folic ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155502753600902

    authors: Kolbach DN,Veraart JC,Hamulyák K,Spaapen LJ,Neumann HA

    更新日期:2002-01-01 00:00:00

  • Bowel bypass arthritis dermatitis syndrome: a histological and electron microscopical study.

    abstract::A case of dermal vasculitis with arthralgia after intestinal bypass surgery is reported. A 36-year-old woman developed arthralgia and skin rash, 1 year after an ileo-jejunal bypass operation was performed for overweight (130 kg). Skin biopsy showed leucocytoclastic vasculitis in the dermis. E.M. study showed clumps of...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Sandbank M,Weltfriend S,Wolf R

    更新日期:1984-01-01 00:00:00

  • Non-specific immunity in patients with primary anogenital warts treated with interferon alpha plus cryotherapy or cryotherapy alone.

    abstract::Combination treatment of primary anogenital warts with subcutaneous interferon alpha 2a plus cryotherapy was no more efficacious than cryotherapy alone. Patients with primary AG warts showed no in vitro or in vivo suppression of non-specific immunity. In patients treated with interferon plus cryotherapy non-specific c...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章

    doi:102340/00015555723940

    authors: Handley JM,Maw RD,Horner T,Lawther H,McNeill T,Dinsmore WW

    更新日期:1992-01-01 00:00:00

  • The protective role of epidermal melanin in a patient with porphyria variegata and vitiligo.

    abstract::To assess the role of epidermal melanin in a patient with porphyria variegata and vitiligo, the MED was determined in pigmented and vitiliginous skin for wavelengths of 310, 405 and 500 nm. The energy required to elicit erythema by irradiating vitiliginous skin at 310 nm was half that for pigmented skin. For 405 nm th...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555581612328

    authors: Westerhof W,Bebelaar D,Cormane RH,Langelaar J,Hup JM

    更新日期:1981-01-01 00:00:00

  • Cutaneous adverse drug reactions seen at a university hospital department of dermatology.

    abstract::Patients with suspected cutaneous adverse drug reactions are often referred to allergy clinics or departments of dermatology for evaluation. These patients are selected compared with patients identified in prospective and cross-sectional studies of hospital populations. This explains the observed variation in prevalen...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0153

    authors: Borch JE,Andersen KE,Bindslev-Jensen C

    更新日期:2006-01-01 00:00:00

  • Red lunulae in severe alopecia areata.

    abstract::The development of red nail lunulae has been extremely rarely described in alopecia areata. We observed 2 patients, a 30-year-old woman and a 61-year-old man, both suffering from severe alopecia areata, and having red lunulae. The colour changes, which developed a few weeks after the acute onset of hair loss, disappea...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555572203205

    authors: Bergner T,Donhauser G,Ruzicka T

    更新日期:1992-01-01 00:00:00