5-S-cysteinyldopa as a substrate for tyrosinase.

Abstract:

:Oxidation of 5-S-cysteinyldopa by mushroom tyrosinase was studied by measuring 5-S-cysteinyldopa consumption with HPLC. 5-S-cysteinyldopa was found to be a substrate for tyrosinase, but our results suggests that a self-catalysed oxidation induced by enzymatically formed 5-S-cysteinyl dopaquinone also takes place. Dopa oxidation by tyrosinase was determined by measuring substrate consumption with HPLC. The oxidation of 5-S-cysteinyldopa was markedly accelerated in the presence of dopa. This could be explained by dopaquinone oxidation of 5-S-cysteinyldopa, which has a lower oxidation potential than dopa.

journal_name

Acta Derm Venereol

authors

Hansson C,Rorsman H,Rosengren E

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

399-402

issue

5

eissn

0001-5555

issn

1651-2057

journal_volume

60

pub_type

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