A possible dysfunction of melanosome transfer in leprosy: an electron-microscopic study.

abstract：:Combination treatment of primary anogenital warts with subcutaneous interferon alpha 2a plus cryotherapy was no more efficacious than cryotherapy alone. Patients with primary AG warts showed no in vitro or in vivo suppression of non-specific immunity. In patients treated with interferon plus cryotherapy non-specific c...

journal_title：Acta dermato-venereologica

authors： Handley JM,Maw RD,Horner T,Lawther H,McNeill T,Dinsmore WW

更新日期：1992-01-01 00:00:00

abstract：:The regulation of IgE production in B lymphocytes of patients with atopic dermatitis by interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) was studied. IL-4 stimulated IgE production in vitro in B-cells of healthy donors and of children with atopic dermatitis, but had only a marginal effect on the high basal level ...

journal_title：Acta dermato-venereologica

authors： Gruner S,Liebenthal C,Heusser C,Brinkmann V,Zwirner A,Reinicke C,Harnack K,Sönnichsen N,Volk HD

更新日期：1991-01-01 00:00:00

abstract：:The aim of this study was to investigate the suitability and effectiveness of heliotherapy in moderate or severe atopic dermatitis in adults in the Canary Islands. A total of 216 patients participated on 6 different 2- or 3-week heliotherapy trips. Using the Severity Scoring of Atopic Dermatitis Index (SCORAD), the se...

journal_title：Acta dermato-venereologica

authors： Autio P,Komulainen P,Larni HM

更新日期：2002-01-01 00:00:00

abstract：:A case of prolonged gonococcal speticemia is presented. Lack of genital symptoms, of demonstrable gonococcal antibodies in whole serum, and initially also of skin lesions contributed to a delayed diagnosis that was finally confirmed by positive blood culture. Evidence of circulating immune complexes was obtained by th...

journal_title：Acta dermato-venereologica

authors： Danielsson D,Norberg R,Svanbom M

更新日期：1975-01-01 00:00:00

abstract：:Mast cells are thought to be involved in neurogenic inflammation in skin, and numerous neuropeptides are known to degranulate mast cells. We monitored histamine release in skin in situ with the microdialysis method after skin challenge with neuropeptide injections (10 microM substance P, vasoactive intestinal peptide ...

journal_title：Acta dermato-venereologica

authors： Huttunen M,Harvima IT,Ackermann L,Harvima RJ,Naukkarinen A,Horsmanheimo M

更新日期：1996-05-01 00:00:00

abstract：:The hypothesis that zinc pyrithione, a highly active anti-dandruff agent, exerts an anti-biosynthetic effect and reduces the epidermal turnover has been tested using guinea pig and hairless mouse skins. It has been found that enhanced mitosis caused by both stripping off the horny layers and sodium dodecyl sulphate, c...

journal_title：Acta dermato-venereologica

authors： Imokawa G,Okamoto K

更新日期：1982-01-01 00:00:00

abstract：:Forty-three nickel-allergic patients (40 females and 3 males) participated in this study which was designed to elucidate the correlation between quantitative in vivo and in vitro responses. All were patch-tested with various concentrations of nickel-sulphate serial-diluted in water. The lowest concentration eliciting ...

journal_title：Acta dermato-venereologica

authors： Al-Tawil NG,Berggren G,Emtestam L,Fransson J,Jernselius R,Marcusson JA

更新日期：1985-01-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of end-stage liver disease. The aim of this controlled cross-sectional study was to assess the association between NAFLD and hidradenitis suppurativa. NAFLD was assessed using hepatic ultrasound. A total of 125 patients with hidradenitis supp...

journal_title：Acta dermato-venereologica

authors： González-Villanueva I,DeGracia C,Planells M,Poveda I,Álvarez P,Schneller-Pavalescu L,Betlloch I,Jemec GBE,Ramos JM,Pascual JC

更新日期：2020-08-18 00:00:00

abstract：:Bullous dermolysis of the newborn (BDN) is a subtype of dystrophic epidermolysis bullosa characterized by rapid improvement in skin fragility within the first months of life, associated with typical immunofluorescence and ultrastructural features. Inheritance can be autosomal dominant or recessive. We report here 4 ca...

journal_title：Acta dermato-venereologica

authors： Diociaiuti A,Castiglia D,Giancristoforo S,Guerra L,Proto V,Dotta A,Boldrini R,Zambruno G,El Hachem M

更新日期：2016-08-23 00:00:00

abstract：:To investigate the function of trichohyalin during terminal differentiation of the skin, immunohistochemical studies were performed on trichohyalin and its related proteins, filaggrin and involucrin, the components of the cornified cell envelope. In skin disorders unrelated to tumours, weak trichohyalin expression was...

journal_title：Acta dermato-venereologica

authors： Lee SC,Lee JB,Seo JJ,Kim YP

更新日期：1999-03-01 00:00:00

abstract：:Hypopigmented macules are frequently observed in the photodamaged skin of elderly people. We undertook to study and treat 2 types of hypomelanosis of photoaged skin. These lesions were: 1) idiopathic guttate hypomelanosis; and 2) macular hypomelanosis. Comparative studies included: 1) high-resolution photography using...

journal_title：Acta dermato-venereologica

authors： Pagnoni A,Kligman AM,Sadiq I,Stoudemayer T

更新日期：1999-07-01 00:00:00

abstract：:Abnormal expression of cell adhesion molecules and related proteins has been observed in various carcinoma cells. We compared expression patterns of desmosomal cadherins, E-cadherin, and cytoplasmic plaque proteins of four different human squamous cell carcinoma cell lines and in vivo squamous cell carcinoma cells wit...

journal_title：Acta dermato-venereologica

authors： Harada H,Iwatsuki K,Ohtsuka M,Han GW,Kaneko F

更新日期：1996-11-01 00:00:00

abstract：:Pruritus is a frequently encountered symptom following burns. Higher intensity of itching has been associated with depth of the wounds and specific body locations but these differences are not well understood. Our aim was to investigate the intensity of post burn pruritus in grafted and non-grafted burns across anatom...

journal_title：Acta dermato-venereologica

authors： Kuipers HC,Bremer M,Braem L,Goemanne AS,Middelkoop E,van Loey NE

更新日期：2015-04-01 00:00:00

abstract：:The effect of topical indomethacin on the weal and flare response was measured in 9 patients with chronic dermographic urticaria. An augmentation of dermographic wealing by topical indomethacin was shown with lowering of the weal threshold from 22.3 +/- 4.7 g/mm2 (mean +/- SEM, n = 9) to 16.4 +/- 3.8 (p < 0.005), but ...

journal_title：Acta dermato-venereologica

authors： Sharpe GR,Shuster S

更新日期：1993-02-01 00:00:00

abstract：:Erythema elevatum diutinum (EED) is a chronic disease with symmetrical persistent erythematous nodules and plaques primarily in an acral distribution. EED is often associated with infections, especially of streptococcals. An immunological reaction has been proposed as pathogenetic mechanism. We describe a patient, who...

journal_title：Acta dermato-venereologica

authors： da Cunha Bang F,Weismann K,Ralfkiaer E,Pallesen G,Lange Wantzin G

更新日期：1986-01-01 00:00:00

abstract：:Low molecular weight oligomers of an epoxy resin of bisphenol A diglycidyl ether type were isolated by gel permeation chromatography. The sensitizing capacity of these oligomers was assessed with the "guinea pig maximization test". The oligomer with the molecular weight of 340 sensitized 80% to 100% of the animals, bu...

journal_title：Acta dermato-venereologica

authors： Thorgeirsson A,Fregert S,Ramnäs O

更新日期：1978-01-01 00:00:00

abstract：:Early alterations in the epidermis of human volunteers following 60 degrees and 95 degrees C burns were studied by means of electron microscopy. The blister was induced at 30 seconds following a 60 degrees C burn for 1 and 3 minutes by disintegration of the basal cells just above the basement membrane, and, in additio...

journal_title：Acta dermato-venereologica

authors： Takigawa M,Ofuji S

更新日期：1977-01-01 00:00:00

abstract：:Two female patients suffering from progressive systemic sclerosis (PSS) of generalized type were treated with estriol for 10 months. Although complete cure was not achieved, considerable beneficial effects were observed in these patients, but no serious side effects. Thus, skin softening was observed on all involved p...

journal_title：Acta dermato-venereologica

authors： Katayama H,Ohsawa K,Yaoita H

更新日期：1984-01-01 00:00:00

abstract：:Sympathetic dysfunction and skin microvascular arteriovenous shunting with insufficient nutritive perfusion and tissue hypoxia have been reported in patients with erythromelalgia. The objective of this study was to determine whether iloprost, a synthetic prostacyclin analogue--primarily a vasodilator and inhibitor of ...

journal_title：Acta dermato-venereologica

authors： Kalgaard OM,Mørk C,Kvernebo K

更新日期：2003-01-01 00:00:00

abstract：:The aim of this study is to assess the associations between chronic spontaneous urticaria (CSU), Helicobacter pylori infection and small intestinal bacterial overgrowth. Forty- eight patients with CSU were studied by scoring the urticaria activity and assesing the quality of life. Patients with H. pylori infection (n=...

journal_title：Acta dermato-venereologica

authors： Campanati A,Gesuita R,Giannoni M,Piraccini F,Sandroni L,Martina E,Conocchiari L,Bendia E,Di Sario A,Offidani A

更新日期：2013-03-27 00:00:00

abstract：:The aromatic retinoids etretinate and acitretin are widely used in the systemic treatment of severe psoriasis. The purpose of the present investigation was to further elucidate the mode of action of acitretin on abnormal keratinization and epidermal hyperproliferation in an in vivo model. Studies on the interference o...

journal_title：Acta dermato-venereologica

authors： Gerritsen MJ,van Pelt JP,van de Kerkhof PC

更新日期：1996-01-01 00:00:00

abstract：:Atopic dermatitis (AD) has a big impact on quality of life. The usefulness of health-related quality of life questionnaires for children with AD in general practice, and the relationship of quality of life to disease severity, as assessed by parents and by investigators, however, is not known. This study used the Infa...

journal_title：Acta dermato-venereologica

authors： van Valburg RW,Willemsen MG,Dirven-Meijer PC,Oranje AP,van der Wouden JC,Moed H

更新日期：2011-03-01 00:00:00

abstract：:Biopsies from a patient with a longstanding form of scleredema adultorum Buschke were analysed for morphological and biochemical changes in the dermal connective tissue. By light microscopy the tissue changes were located to the deep part of the reticular dermis. Therefore dermal tissue was separated into a superficia...

journal_title：Acta dermato-venereologica

authors： Roupe G,Laurent TC,Malmström A,Suurküla M,Särnstrand B

更新日期：1987-01-01 00:00:00

abstract：:Fourteen patients with monosymptomatic delusions of infestation were followed-up 19-48 months after treatment with pimozide was terminated. Seven patients had remained in remission since the treatment. Three had developed relapses, but were without symptoms with intermittent treatment. Four patients responded poorly t...

journal_title：Acta dermato-venereologica

authors： Lindskov R,Baadsgaard O

更新日期：1985-01-01 00:00:00

abstract：:The anti-inflammatory mechanisms of minocycline, an antibiotic used in the treatment of the inflammatory component of acne, are only partially understood. In addition to inflammation due to cytokines (IL-1, IL-6, TNF-alpha, etc.), recent studies have shown that neuropeptide-mediated neurogenic inflammation may play an...

journal_title：Acta dermato-venereologica

authors： Sainte-Marie I,Tenaud I,Jumbou O,Dréno B

更新日期：1999-07-01 00:00:00

abstract：:Thirteen patients with port wine stains (PWS) were treated with argon laser therapy. Before and at different points in time following treatment, skin blood perfusion and temperature were mapped with laser Doppler imaging and thermography. In nine patients no elevation in blood perfusion was observed in the PWS in comp...

journal_title：Acta dermato-venereologica

authors： Troilius A,Wårdell K,Bornmyr S,Nilsson GE,Ljunggren B

更新日期：1992-01-01 00:00:00

abstract：:Gold sodium thiosulfate, inserted in the patch test standard series, gives a surprisingly high yield of positive reactions, about 10% of tested eczema patients, but with a low degree of clinical relevance. A histopathological study on patch test reactions was carried out in patients selected because of a combined cont...

journal_title：Acta dermato-venereologica

authors： Möller H,Larsson A,Björkner B,Bruze M

更新日期：1994-11-01 00:00:00

abstract：:Previous studies on skin topically photosensitized with trimethylpsoralen and subsequently irradiated with long-wave UV light have demonstrated an increase in melanosome size and changes in the distribution patterns of melanosomes, suggesting the possibility of gene derepression or the induction of a somatic mutation ...

journal_title：Acta dermato-venereologica

authors： Zaynoun S,Konrad K,Gschnait F,Wolff K

更新日期：1977-01-01 00:00:00

abstract：:Lower-limb ulcers in systemic sclerosis patients are rarely reported. The aim of this study was to describe the main causes and outcomes of lower-limb ulcers in systemic sclerosis patients and to assess factors associated with ischaemic causes (arterial disease and/or microvascular impairment). A retrospective, multic...

journal_title：Acta dermato-venereologica

authors： Bohelay G,Blaise S,Levy P,Claeys A,Baudot N,Cuny JF,Maillard H,Granel-Brocard F,Boyé T,Lok C,Bénéton N,Francès C,Senet P

更新日期：2018-07-11 00:00:00

abstract：:Anorexia nervosa and bulimia nervosa are common yet occult eating disorders which each affect between 1 and 2% of young adult women in the UK (1). Cutaneous signs may provide valuable clues allowing earlier diagnosis. Eating disorders may both imitate (Table I) and complicate other medical illnesses, resulting in unne...

journal_title：Acta dermato-venereologica

authors： Siddiqui A,Ramsay B,Leonard J

更新日期：1994-01-01 00:00:00