Abstract:
:Lipotropes (choline, methionine, folic acid, and vitamin B12) are required for normal metabolic function at the cellular and subcellular levels. Deficiencies of any or all of them to a point of influence on methyl group metabolism has a profound effect on synthesis of cellular macromolecules and on cell proliferation. Lipotrope deficiency results in a diminished immunocompetence and an increased susceptibility to a number of types of cancer in experimental animals. A challenge now being addressed is to identify the linkage between lipotropes, the immune system, and cancer and to determine mechanisms which can be useful in cancer prevention.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Newbene PM,Nauss KM,de Camargo JLsubject
Has Abstractpub_date
1983-05-01 00:00:00pages
2426s-2434sissue
5 Suppleissn
0008-5472issn
1538-7445journal_volume
43pub_type
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