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Effect of althesin anesthesia on blood loss during therapeutic abortion. A comparison with local and thiopental anesthesia.

Abstract：

:During recent years, the use of steroid anesthesia has rapidly increased. In our hospital, a number of surgical procedures have been performed under Althesin anesthesia, and in some cases the peroperative bleeding seemed to be rather profuse. Blood loss was studied in 90 healthy women in the first trimester of pregnancy undergoing therapeutic abortion using different types of anesthesia. The patients were divided into three equal groups according to the duration of pregnancy. In each group, 10 patients underwent operation under local anesthesia, 10 under thiopental anesthesia and 10 under Althesin. In all three groups, blood loss was the smallest when local anesthesia was used (Fig 1). Amounting to only one third to one half of that occurring under thiopental anesthesia. Under thiopental anesthesia the blood loss gradually increased with increasing gestational age with moderate variations. Alternatively, in this investigation, Althesin anesthesia was characterized by pronounced blood loss, particularly in the ninth and tenth weeks of pregnancy, and in some cases by rather profuse bleeding. We find that Althesin anesthesia should be used for gynecological surgery only in departments which are equipped to control profuse bleeding and possible cardiovascular complications. :During recent years, the use of steroid anesthesia has rapidly increased. A number of surgical procedures have been performed under Althesin anesthesia, and in some cases the peroperative bleeding seemed to be rather profuse. Blood loss was studied in 90 healthy nulliparous women, ages 15-39 years, in the 1st trimester of pregnancy, undergoing therapeutic abortion with different types of anesthesia. The patients were divided into 3 equal groups of 10 persons according to duration of pregnancy. Group 1 patients underwent surgery under local anesthesia, group 2 under thiopental anesthesia, and group 3 under Althesin. Blood loss in all 3 groups was smallest when local anesthesia was used (only 1/3 - 1/2 of that occurring under thiopental anesthesia). With thiopental anesthesia, the blood loss gradually increased with increasing gestational age with only moderate variations. Alternatively, in this investigation, Althesin anesthesia was characterized by pronounced blood loss, particularly in group 2 (p 0.05) and particularly in weeks 9-10 of pregnancy. Althesin was also associated with a wide range in blood loss, especially in group 2 (40-300 ml). The occurrence of profuse hemorrhage, seen in those administered Althesin, may be hazardous to those with cardiovascular difficulty. Thus it should be used for gynecological surgery only in departments equipped to control profuse bleeding and possible cardiovascular complications.

journal_name

Acta Obstet Gynecol Scand

journal_title

Acta obstetricia et gynecologica Scandinavica

authors

Møller BR,Mommsen S,Bøggild-Madsen NB,Vestersgaard-Andersen TB,Olcott A,Hansen JT

doi

10.3109/00016347909154072

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

481-3

issue

eissn

0001-6349

issn

1600-0412

journal_volume

pub_type

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Effect of althesin anesthesia on blood loss during therapeutic abortion. A comparison with local and thiopental anesthesia.