Abstract：
:Overall 30 patients with multiple myeloma (MM) were examined for immunological and rheological parameters. MM was shown to be marked by imbalance of immunobiological reactivity, with the greatest changes being seen in the B cell immunity system. MM is also characterized by marked rheological shifts related to the immunological alterations and underlying the hyperviscosity syndrome and heart failure. Administration of polychemotherapy resulted in a decrease of the count of B lymphocytes, circulating immune complexes; a tendency toward normalization of the rheological blood properties was observed. Introduction of plasmapheresis into the treatment program of the patients noticeably raised the treatment efficacy.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Abdulkadyrov KM,Bessmel'tsev SS,Liubimova NIusubject
Has Abstractpub_date
1991-01-01 00:00:00pages
122-6issue
7eissn
0040-3660issn
2309-5342journal_volume
63pub_type
杂志文章abstract：:A study was made of the possibilities of an individual approach to intraarticular administration of protease inhibitors, cytostatics and orgoteine in patients with rheumatoid arthritis (RA). The activity of hyaluronidase, superoxide dismutase, the level of rheumatoid factor and the phagocyte count in synovial fluid we...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Clinical and instrumental manifestations of disorders of the regional blood circulation were studied in 47 patients with sclerodermia systematica. Hemodynamic changes of the lesser circulation were marked in patients under 44 with more active disease, longer disease duration, pulmonary pathology and cardiac decompensa...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：AIM:To characterize clinically and electrocardiographically the condition of the heart in chronic iron deficient anemia (IDA), to study hemodynamic mechanisms of heart impairment for early detection of diastolic myocardial dysfunction in long-term course of sideropenia. MATERIAL AND METHODS:Clinical and ECG examinatio...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:The authors assessed the time course of the S-T segment in 12 standard and monitor ECG leads and the time course of MB CPK fraction activity and Mg blood concentration in 34 patients with acute myocardial infarction. After the detection of thrombotic occlusion of the coronary artery they received thrombolytic therapy ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:The antigenic composition of tissues was shown to be of importance in the formation of bronchial asthma on the basis of the clinicoimmunological data with regard to histocompatibility antigens in 235 patients suffering from bronchial asthma and preasthma. Well-defined correlations were established between the developm...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:A study was made of the presence of antinuclear antibodies to Ro, La, nDNA, RNP and Sm in 18 patients with Sjögren's disease (SD) and in 13 patients with Sjögren's syndrome (SS). Anti-Ro and/or anti-La were revealed in 12 SD patients (67%) and in 3 SS patients (23%, P less than 0.05) only. Anti-nDNA and anti-RNP were ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：AIM:to study the nature of pain in hemophilic arthropathy and its prevention ways used by patients with hemophilia. SUBJECTS AND METHODS:A prospective, multicenter, cross-sectional study was conducted to interview 136 patients with hemophilia A or B. The survey included 32 points, including questions about drug and no...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,多中心研究
doi：10.17116/terarkh201688784-88
更新日期：2016-01-01 00:00:00
abstract：AIM:The primary objective of this study was to describe clinical, virusological and immunological characteristics of hospitalised HIV-infected patients, who had different stages of the disease. MATERIALS AND METHODS:This study was conducted at Moscow Infectious Diseases Hospital №2 in 2012-2015. We have clinically obs...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/terarkh201890114-23
更新日期：2018-11-15 00:00:00
abstract：:The authors analyze the results of investigations in accordance with the WHO program "MONICA" in one of the districts of Novosibirsk. The bases of the objective information system pertaining to the tendencies in mortality, morbidity and lethality due to cardiovascular diseases, the prevalence of risk factors in the po...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：AIM:To assess efficacy of vaccine against viral hepatitis B (VHB) in adults after achievement of acute leukemia (AL) remission. MATERIAL AND METHODS:Specific prevention of VHB was made in 30 AL patients with recombinant vaccine Engerix B by two schemes: 0-1-2-12 and 0-1-2-6 months with double adult dose 40 mcg. Effica...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:To investigate sex- and age-specific features of radiographic abnormalities in rheumatoid arthritis (RA) patients, radiographic signs in hands and feet were assessed using Steinbroker criteria. A score system from 0 to 3 was also introduced to evaluate every radiographic feature: osteoporosis, cysts, joint space narro...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：AIM:To compare the efficacy of monotherapy with quadropril (spirapril) vs captopril in essential hypertension. MATERIAL AND METHODS:20 female patients aged 55 +/- 2 years with moderate hypertension (WHO classification) were included in the study. 16 patients had congestive heart failure stage II NYHA and 4 patients st...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The clinical and morphological data were studied and compared in 84 patients with Flexner's dysentery and 40 with Sonne dysentery. It is established that more pronounced and lingering colitic syndrome typical of Flexner's dysentery is related to more lasting persistence of causative agents in the superficial epitheliu...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:The article deals with current studies on the role of uric acid (UA) in development of cardiovascular diseases. The results of large prospective trials are presented which have revealed a pathogenetic role of UA in development of essential hypertension. Clinical trials demonstrated elevated concentrations of UA in hyp...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：:Borreliosis after sucking ticks is an acute problem in the world. People do not go to doctors after that often, which leads to the development of various complications. Thrombosis of veins of various localization can be one of them. Thrombosis of the portal vein represents a significant problem too with high morbidity...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/terarkh2018901179-89
更新日期：2018-11-22 00:00:00
abstract：AIM:To assess the role of angiogenic factors (vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) in interstitial lung diseases (ILD), such as fibrosing alveolitis, sarcoidosis. SUBJECTS AND METHODS:The blood levels of endothelial dysfunction and neoangiogenesis markers (ET-1 and VEGF) were investigated ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：AIM:To assess factors of an unfavourable prognosis in a group of intermediate risk of B-cell chronic lymphoid leukemia (BCCLL). MATERIAL AND METHODS:206 BCCLL patients (mean age 55.5 years, male/female = 1.66) entered the study conducted by Hematological Research Center in 1992-2000. RESULTS:Nine patients under 35 ye...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Serum samples obtained from 33 patients with acute rheumatic fever (ARF), 60 patients with rheumatic heart disease (RHD) and 30 adult healthy persons have been studied. Antibodies to streptococcal A polysaccharide (SAP) and lypoteichoic acid (LTA) were examined by ELISA, to streptolysin O by standard technique. SAP an...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:In conditions of climate warming with an increase in heat waves associated with an increase in cardiovascular morbidity and mortality, the particular interest is the effect of cardiovascular drugs on adaptation to high temperatures. The review reflects the results of European and domestic studies on the safety of ther...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：10.26442/00403660.2019.01.000038
更新日期：2019-03-11 00:00:00
abstract：AIM:To study renal functional reserve and 24-h beta 2-microglobulinuria (B2-MGU) in patients with different stages of essential hypertension (EH) and to evaluate acceptability of these parameters as early markers of preclinical renal impairment in EH. METHODS:We examined 150 patients (mean age 42.1 +/- 3.4 years) with...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:In the article, we report the causes of pulmonary hemorrhage (PH) according to the literature data and own experience, with an emphasis on patients suffering from rheumatic diseases. Methods of diagnosis and modern approaches to the treatment of PH are analyzed. :В представленной статье на основе данных литературы и ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/00403660.2019.05.000234
更新日期：2019-05-15 00:00:00
abstract：AIM:To clarify the effect of cyclosporin A (CSA) on the apoptosis and proliferative activity of bone marrow cells in patients with aplastic syndromes by trepanobiopsy evidence. MATERIALS AND METHODS:The TUNEL immunohistochemical assay was used to study apoptosis of bone marrow cells in the histological specimens from ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The results of hemodialysis therapy given in 1988-1994 to 57 patients with acute renal failure at the age of 17-62 years in hemorrhagic fever with renal syndrome (HFRS) are provided. A total of 306 procedures were performed. Hemodialysis was initiated early, before clinical presentation of uremia. The indications for ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:An organized community numbering 900 normal subjects aged 18 to 19 years were examined. Acute pneumonia was encountered in 15% of persons of the group under study per year. To identify persons with premorbid condition of nonspecific pulmonary diseases, anamnestic screening and outpatient examinations (microbiological ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：AIM:To compare the impact of cardiac resynchronization therapy (CRT) on survival in patients with ischemic and non-ischemic cardiomyopathy (CMP) in clinical practice. SUBJECTS AND METHODS:The study enrolled 206 patients with NYHA Functional Class II-IV chronic heart failure (CHF) and a left ventricular ejection fracti...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：AIM:To investigate a clinicopathogenetic role of fibrinolysis regulators in chronic viral hepatitis (CVH) and viral cyrrhosis of the liver (CL). MATERIAL AND METHODS:Seventy patients entered the study: 10 patients with CVH B, 33--with CVH C, 6--with CVH D, 21--with viral CL (HCV-associated in 14 cases and HBV-associat...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:A 2-week clinical trial of cream dolgit efficacy and tolerance in 76 patients with primary osteoarthritis in 8 rheumatological centers showed this preparation to reduce local pain syndrome in 70.1%, palpation pain sensitivity in 79.2%, joint swelling in 75.5% of patients. Unwanted reactions in the form of skin itch at...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1995-01-01 00:00:00
abstract：:Therapy with tyrosine kinase inhibitors (TKI) allows to achieve a deep molecular response in 6070% of patients with chronic myeloid leukemia (CML). According to the current guidelines CML patients receive a long-term treatment with TKI in standard dose. The frequently observed adverse effects (AE) of TKI therapy are m...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/00403660.2020.07.000789
更新日期：2020-09-01 00:00:00
abstract：AIM:to evaluate the efficacy of cyclopheron used in patients with mild clinical manifestations of focal and infiltrative pulmonary tuberculosis (PT). SUBJECTS AND METHODS:Thirty first detected patients with PT, in whom a complex of their etiotropic therapy comprised cyclopheron, and 32 similar patients who received et...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2010-01-01 00:00:00
abstract：AIM:To study heart rate variability (HRV) according to 24-h Holter monitoring of ECG in patients with ischemic heart disease (IHD) and to examine effects of tianeptine on HRV. MATERIAL AND METHODS:Twenty eight patients with IHD (17 males and 11 females aged 40-70 years) with a verified IHD diagnosis and atherosclerosi...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
