[Role of uric acid in development of essential hypertension: modern conceptions].

Abstract:

:The article deals with current studies on the role of uric acid (UA) in development of cardiovascular diseases. The results of large prospective trials are presented which have revealed a pathogenetic role of UA in development of essential hypertension. Clinical trials demonstrated elevated concentrations of UA in hypertensive patients. Experimental evidence suggests UA involvement in the processes of nonspecific inflammation, oxidant stress, endothelial dysfunction. It is shown that elevated UA levels in blood serum lead to affection of target organs.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Polovitkina OV,Oshchepkova EV,Dmitriev VA,Titov VN

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

38-41

issue

8

eissn

0040-3660

issn

2309-5342

journal_volume

83

pub_type

杂志文章,评审
  • [Intradialysis hypotension: causes and sequelae].

    abstract:AIM:To study causes and sequelae of intradialysis hypotension (IH) in patients with terminal renal failure (TRF). MATERIAL AND METHODS:Forty one patients with TRF on chronic hemodialysis (CH) were divided into two groups. The study group consisted of 24 patients with episodes of IH. Seventeen patients of the control g...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Milovanova LIu,Nikolaev AIu,Safonov VV,Milovanov IuS

    更新日期:2003-01-01 00:00:00

  • [Comparative efficacy of combined therapy with preductal and amino acid composition in elderly patients with coronary heart disease and class II-III angina].

    abstract:AIM:A comparative analysis of effectiveness of combined therapy including trimetazidine (preductal) and composition of amino acids (glutamic acid, glycin and cystein) in elderly patients with coronary heart disease and angina of functional class II-III (FC II-III). MATERIALS AND METHODS:60 patients (47 females and 13 ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Zaslavskaia RM,Kelimberdieva ES,Komissarova IA,Teĭblium MM,Goncharov LF,Goncharova ZF,Akhmetov KZh

    更新日期:1999-01-01 00:00:00

  • [Level of specific binding of beta-adrenergic ligands and the morphofunctional properties of erythrocytes in bronchial asthma].

    abstract::Peripheral blood erythrocytes of patients with bronchial asthma (BA) and preasthma (PA) were investigated using the following methods: 1) the radiochemical method--the level of specific binding of beta-adrenergic ligands; 2) direct erythrocytometry--erythrocyte diameter; 3) the cytochemical method (paraldehyde fuchsin...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Zhikharev SS,Pertseva MN,Kuznetsova LA,Mineev VN,Iablonskaia VN

    更新日期:1988-01-01 00:00:00

  • [Possibilities of the ultrasonic method of examination in identifying large lesions of the abdominal cavity and small pelvis organs].

    abstract::Analysis was made of 13201 ultrasonic studies (USS) of abdominal and small pelvic organs in 5500 patients admitted to the therapeutic department of the multiple-discipline hospital to identify sizable injuries. As many as 176 sizable injuries to the liver, kidneys, gallbladder, pancreas, retroperitoneal space and othe...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kotliarov PM,Anan'eva AA

    更新日期:1989-01-01 00:00:00

  • [Role of pFox inhibitors in the treatment of patients with acute myocardial ischemia].

    abstract:AIM:To evaluate the anti-ischemic and anti-anginal efficacy of meldonium (Idrinol) in its short-term use as part of combination therapy in patients with chronic heart failure in the early post-infarction period. SUBJECTS AND METHODS:The investigation enrolled 60 patients (men and women) aged 45 to 75 years at weeks 3-...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Statsenko ME,Turkina SV,Shilina NN

    更新日期:2014-01-01 00:00:00

  • [Choice of treatment policy for hypertensive patients: its individualization, indications, and criteria].

    abstract::Fundamental innovations in the study of the regulatory mechanisms of circulation in the past 20-30 years (evidence for the role of the endothelium in local hemodynamic control, the basic significance of the tissue link of the angiotensin mechanism (A-II) of not only as a vasoconstrictor, but also a trigger of a slow p...

    journal_title:Terapevticheskii arkhiv

    pub_type: 社论

    doi:

    authors: Gogin EE

    更新日期:2010-01-01 00:00:00

  • [Basal and food-stimulated blood gastrin in duodenal ulcer].

    abstract::It has been demonstrated that the basal gastrin level in the blood of patients with peptic ulcer of the duodenum is similar to that in normal subjects. Food stimulation raises blood gastrin in normal subjects and patients. However, in patients, the peak of the blood hormone rise is higher, with this rise lasting for a...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Shvarts VIa,Kuznetsov BG,Frolkov VK,Saakian AG

    更新日期:1984-01-01 00:00:00

  • [A patient with mitral prolapse: differential intervention programs in general medical practice].

    abstract:AIM:To develop and implement intervention programmes for patients with mitral prolapse (MP) under real conditions of general medical practices of Russia in the transition period. MATERIAL AND METHODS:The MP register covered 208 patients among the adult population (n = 3346) of 2 districts served by general practitione...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Movshovich BL,Lisitsa DN

    更新日期:2002-01-01 00:00:00

  • [The cyclicity of changes in the autonomic regulation of the hemodynamics and the effects of clofelin in women with hypertension].

    abstract::As many as 56 healthy women and 45 women of reproductive age, suffering from essential hypertension (EH) were examined for the effect of ovarian cycle phases on vegetative regulation of central hemodynamics and pharmacodynamic effects of hemiton. The healthy persons in the phase of proliferation (I) and secretion (III...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Veber VR,Kolodina EA,Kerimkulova AS,Kazymov MS

    更新日期:1992-01-01 00:00:00

  • ["Double porphyrias" (a review of the literature and case report)].

    abstract::The authors review literature data on porphyrias with combining enzymopathies in heme biosynthesis system, report a case of porphyria cutanea tarda and porphyria variegata registered simultaneously in a male patient clinically and confirmed biochemically. The patient's mother had elevated levels of fecal protoporphyri...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Krivosheev BN,Lukina IL,Kovalenko LI,Krivosheev AB

    更新日期:1993-01-01 00:00:00

  • [Role of fibroblast growth factor 23 in the development of cardiovascular diseases in patients with end-stage renal failure on programmed hemodialysis].

    abstract:AIM:To determine the nature of changes in fibroblast growth factor 23 (FGF-23) and other bone mineral metabolism parameters detectable in the blood of patients with end-stage chronic renal failure (CRF) and to analyze their links to the development of cardiovascular events in uremic intoxication. SUBJECTS AND METHODS:...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh2016881251-56

    authors: Dzgoeva FU,Sopoev MY,Bestaeva TL,Khamitsaeva OV,Ktsoeva FA,Sageeva RO

    更新日期:2016-01-01 00:00:00

  • [The interdigestive phasic motility of the gallbladder and bile excretion in healthy subjects and in patients with duodenal peptic ulcer].

    abstract::Interdigestive phasic motility of the gallbladder and bile excretion into the duodenum were studied in 100 patients with duodenal ulcer (DU) and 20 healthy subjects. Gall bladder motility and bile excretion in both healthy and DU subjects directly depended on interdigestive phasic activity of the duodenum and gastric ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Reshetilov IuI,Orlovskiĭ VF,Surmylo NN,Kuznetsova LF,Protsenko NN,Klavdieva EIu,Perkina AA

    更新日期:1995-01-01 00:00:00

  • [Clinical significance of disorders of local defense in nonspecific lung diseases].

    abstract::A study was made of the humoral (IgA, G, M, lysozyme and lactoferrin) and cellular links (phagocytic activity of alveolar macrophages) of pulmonary local defence as well as sputum adhesion in 177 patients with chronic nonspecific pulmonary diseases (80 patients with chronic obstructive bronchitis, 54 patients with pyo...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Dvoretsiiĭ LI,Didkovskiĭ NA,Charlyev G

    更新日期:1986-01-01 00:00:00

  • [Immunologic reactivity of the body and clinico-roentgenological picture of acute pneumonia in adults].

    abstract::There was No correlation between the state of immunological reactivity in patients with acute pneumonia and the nature of infiltration of the pulmonary tissue (focal, confluent). Indices characterizing the cellular and humoral immunity links, were, to a large extent, related to a course of disease (complicated, uncomp...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Fomina TD,Pokhodzeĭ IV

    更新日期:1986-01-01 00:00:00

  • [Disorders of regional blood circulation in systemic scleroderma: early diagnosis and possibility of its correction].

    abstract::Clinical and instrumental manifestations of disorders of the regional blood circulation were studied in 47 patients with sclerodermia systematica. Hemodynamic changes of the lesser circulation were marked in patients under 44 with more active disease, longer disease duration, pulmonary pathology and cardiac decompensa...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Bagirova GG,Doroshenko IuA

    更新日期:1988-01-01 00:00:00

  • [Nebivolol effects on the cardiovascular system and the kidneys in pregnant and puerperal women with hypertension].

    abstract:AIM:To study nebivolol efficacy in pregnant and puerperal women with hypertension. MATERIAL AND METHODS:Monitoring of endothelial function, central and peripheral hemodynamics (HD), myocardial function, intrarenal circulation and microalbuminuria (MAU) was performed in 90 pregnant (67 hypertensive and 23 normotensive)...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:

    authors: Tkacheva ON,Vertkin AL,Barabashkina AV,Vasil'eva AV,Razguliaeva NF

    更新日期:2006-01-01 00:00:00

  • [The epidemiology of the risk factors for cardiovascular diseases and their combination among the male population in the cities of different regions of the CIS Nations and Baltic states. A cooperative study].

    abstract::The prevalence of risk factors (RF) to develop cardiovascular disorders alone and in combination has been studied in males aged 20-54 differing by occupation and education. They lived in various cities of CIS and Baltic States. It was established that RF alone and in combination are common among the male population. T...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Konstantinov VV,Zhukovskiĭ GS,Burlutskiĭ GI,Malakhov VN,Konstantinova OS,Kapustina AV,Shestov DB,Deev AD,Smirnova IP,Serova NV

    更新日期:1993-01-01 00:00:00

  • [New cases of helicobacter pylori associated duodenal ulcer].

    abstract:AIM:Generalization of the results obtained through analysis of examinations of new cases of duodenal ulcer (DU) with patients suffering from DU of different duration, made in two main aspects: the patients' Helicobacter pylori (HP) status determined by histological, bacteriological, immunological studies and rapid urea...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Minushkin ON,Vasil'eva NIu,Kudriavtseva LV

    更新日期:1998-01-01 00:00:00

  • [The role of suprasegmental and segmental autonomic disorders in the development of muscular syndrome of rheumatoid arthritis].

    abstract:UNLABELLED:AID: To investigate the role of suprasegmental (anxious disorders) and segmental vegetative disorders (dysfunction of neuromuscular transmission and cutaneous microcirculation) in pathogenesis of muscular syndrome of rheumatoid arthritis (RA). MATERIAL AND METHODS:MMPI, Beck's questionnaire, Spilberger's te...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ulanova EA,Mach ES,Korsakova IuO

    更新日期:2002-01-01 00:00:00

  • [Carbohydrate metabolism in patients with acromegaly and Itsenko-Cushing disease].

    abstract::The relevance of investigating carbohydrate metabolism (CM) in patients with acromegaly and Itsenko-Cushing disease is attributable to frequent glucose metabolic disturbances, on the one hand, and to difficulties in choosing sugar-lowering therapy in these categories of patients, on the other. The efficiency of hyperg...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh2015871098-104

    authors: Matchekhina LV,Belaya ZE,Melnichenko GA,Shestakova MV

    更新日期:2015-01-01 00:00:00

  • [The ability of partusisten to improve kidney excretory function in the initial stage of kidney failure in patients with chronic glomerulonephritis].

    abstract::To assess the effect of partusisten (fenoterol) on excretory function of the kidneys, the drug was administered per os in a dose of 10 mg/day for 7-10 days in 17 chronic glomerulonephritis patients with initial forms (stages I-IIA) of renal failure. A dramatic increase of glomerular filtration, a certain rise of tubul...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Skipskiĭ IM,Komandenko MS,Shulutko BI,Zamoskovskaia GA

    更新日期:1991-01-01 00:00:00

  • [Changes in the indicators of the fibrinolytic and kallikrein-kinin systems in patients with calculous pyelonephritis].

    abstract::A total of 48 patients with calculous pyelonephritis were examined before and after surgery. A study was made of the fibrinolytic system (according to the status of XIIa kallikrein-dependent fibrinolysis, lysis of the plasma clots and euglobulin lysis) and of the kallikrein-kinin system of the plasma (according to kal...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Neĭmark AI,Mazyrko AV

    更新日期:1984-01-01 00:00:00

  • [Molecular and cellular mechanisms of compensation for respiratory failure in nonspecific lung diseases].

    abstract::Some molecular and cellular mechanisms of compensation for respiratory failure (RF) were examined in 90 patients with nonspecific pulmonary diseases. In acute RF, the content of 2,3-DPH in red blood cells was increased. As RF progressed, the compensatory-adaptation reaction became less marked. In chronic RF, the 2,3-D...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Landyshev SIu,Borodin EA

    更新日期:1985-01-01 00:00:00

  • [Modifying effect of physical activity on genetic predisposition to obesity].

    abstract:AIM:To evaluate the modifying effect of physical activity on the association of ADRB3, CLOCK, FABP2, FTO, PPARA, PPARD, PPARG, PPARGC1A, SHBG, UCP2 and UCP3 gene polymorphisms with body mass index (BMI), body fat mass, and risk of obesity. SUBJECTS AND METHODS:The investigation enrolled 582 students and 215 athletes w...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Egorova ES,Mustafina MM,Gabbasov RT,Borisova AV,Akhmetov II

    更新日期:2014-01-01 00:00:00

  • [Structural and electrophysiological characteristics of the heart function during paroxysmal atrial fibrillation].

    abstract:AIM:To examine structural and electrophysiological predictors of the onset and establishment as chronic of cardiac fibrillation (CF). MATERIAL AND METHODS:Echocardiography, transesophageal electrophysiological examination of the heart were performed in 420 cases of paroxysmal cardiac fibrillation (PCF). They were diag...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Iskenderov BG,Rakhmatullov FK

    更新日期:2001-01-01 00:00:00

  • [The nature of the changes in the repolarization complex of the ECG in patients with arterial hypertension and left ventricular hypertrophy].

    abstract::Altogether 58 patients suffering from arterial hypertension (AH) were examined. The patients with left ventricular hypertrophy (LVH) and changes in the ST-T demonstrated a high correlation between an increase of the end systolic tension (EST) and interval elongation and the minimal size of the left ventricle before mi...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Gurgenian SV,Mikaelian ES,Vardanian ZhG,Babaian AS,Edilian LB,Vatinian SKh

    更新日期:1992-01-01 00:00:00

  • [Factors of an unfavorable prognosis in patients with B-cell chronic lymphoid leukemia: a retrospective analysis of 206 cases].

    abstract:AIM:To assess factors of an unfavourable prognosis in a group of intermediate risk of B-cell chronic lymphoid leukemia (BCCLL). MATERIAL AND METHODS:206 BCCLL patients (mean age 55.5 years, male/female = 1.66) entered the study conducted by Hematological Research Center in 1992-2000. RESULTS:Nine patients under 35 ye...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Nikitin EA,Lorie IuIu,Melikian AL,Samoĭlova RS,Bulycheva TI,Obukhova TN,Kaplanskaia IB,Doronin VA,Kolosova LIu,Goriacheva SR

    更新日期:2003-01-01 00:00:00

  • The impact of therapeutic plasma exchange and double filtration plasmapheresis on hemostasis in renal transplant recipients.

    abstract:AIM:To investigate the impact of double filtration plasmapheresis (DFPP) and therapeutic plasma exchange (TPE) on hemostasis in renal transplant recipients. MATERIALS AND METHODS:54 renal transplant patients with an acute humoral rejection were treated with therapeutic apheresis methods: 24 patients with DFPP and 30 p...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/terarkh201890622-27

    authors: Vatazin AV,Zulkarnaev AB

    更新日期:2018-06-20 00:00:00

  • [Level of blood uric acid in patients with postinfarction heart failure].

    abstract:AIM:To evaluate uric acid (UA) levels in patients with postinfarction chronic cardiac failure (CCF) and to investigate correlation between accumulation of uric acid, CCF severity and some other parameters. MATERIAL AND METHODS:UA levels were determined with enzyme immunoassay and acid-base status of capillary and veno...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Tereshchenko SN,Levchuk NN,Drozdov VN,Moiseev VS

    更新日期:2000-01-01 00:00:00

  • [The joint use of plasmosorption and enterosorption in the combined treatment of patients in the acute period of a myocardial infarct].

    abstract::Plasmosorption and enterosorption were assigned to 35 acute myocardial infarction (AMI) patients. Plasmosorption was performed within an hour since AMI onset followed by a 5-day course of enterosorption (enterosorbent YO-A in a dose 30 g/day). The above combination produced a positive effect on hemodynamics and blood ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Abdullaev AA,Kuznetsov AN,Liusov VA

    更新日期:1995-01-01 00:00:00