Abstract:
:Clinically diagnosed cases with different grades of rheumatoid arthritis (RA) were studied for (a) cryoglobulin content (b) constituents of cryoglobulins, and (c) rheumatoid factor (RF) titers in sera and cryoglobulins. Of 60 patients, 28 (46.66%) had significantly high levels of cryoglobulins and were mainly distributed in the severe group. Significant amounts of IgG and IgM were found in the cryoglobulins of the 15 cases of RA studied. Ten of these cases had detectable C3 in their cryoglobulins. Of 20 cases of RA, 10 had detectable levels of RF in their cryoglobulins, as shown by the latex agglutination method. There was no significant correlation between the RF titers of cryoglobulins and the RF titers in the corresponding sera or the quantity of IgM and IgG components in them. Since the RF titer in cryoglobulin seemed to indicate the severity of the disease, the use of this parameter is proposed for diagnosis and prognosis of RA.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Chattopadhya D,Ravindran B,Prakash Kdoi
10.1007/BF00541520subject
Has Abstractpub_date
1985-01-01 00:00:00pages
181-4issue
4eissn
0172-8172issn
1437-160Xjournal_volume
5pub_type
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541379
更新日期:1987-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00296-010-1507-1
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00332564
更新日期:1991-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
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更新日期:2014-12-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
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更新日期:2018-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:1988-01-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2013-06-01 00:00:00
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journal_title:Rheumatology international
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-05-01 00:00:00