Mexiletine: double-blind comparison with procainamide in PVC suppression and open-label sequential comparison with amiodarone in life-threatening ventricular arrhythmias.

abstract：BACKGROUND:Many young investigators are interested in cardiovascular (CV) outcomes research; however, the current training experience of early investigators across the United States is uncertain. METHODS:From April to November 2014, we surveyed mentees and mentors of early-stage CV outcomes investigators across the Un...

journal_title：American heart journal

authors： Khazanie P,Al-Khatib SM,Wang TY,Crowley MJ,Kressin NR,Krumholz HM,Kiefe CI,Wells BL,O'Brien SM,Peterson ED,Sanders GD

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Older adults presenting with acute myocardial infarction (MI) often have multivessel coronary artery disease amenable to percutaneous coronary intervention (PCI), yet the risks of multivessel intervention may outweigh potential benefits in these patients. We sought to determine if nonculprit intervention dur...

journal_title：American heart journal

authors： Wang TY,McCoy LA,Bhatt DL,Rao SV,Roe MT,Resnic FS,Cavender MA,Messenger JC,Peterson ED

更新日期：2016-02-01 00:00:00

abstract：:Fatal myocardial infarction occurring in a neonate is reported. The patient presented with a clinical picture of cardiogenic shock simulating a hypoplastic left heart syndrome. Etiology of the myocardial infarction is uncertain for the coronary arteries were patent, anatomically and histologically normal, and there wa...

journal_title：American heart journal

authors： Iannone LA,Duritz G,McCarty RJ

更新日期：1975-02-01 00:00:00

abstract：:The Institute of Medicine report on the frequency and consequences of medical errors in clinical practice has stimulated physicians to evaluate current practice and means of improving medical care. In the treatment of patients with acute myocardial infarction, previous studies have found that dosing of fibrinolytic th...

journal_title：American heart journal

authors： Cannon CP

更新日期：2000-12-01 00:00:00

abstract：:In vitro studies have established that intravascular ultrasound is a reliable technique for accurate assessment of vascular anatomic structure and disease conditions before and after intervention. In addition, quantitative data from intravascular ultrasound studies correspond well with histologic findings, which serve...

journal_title：American heart journal

authors： Gussenhoven EJ,van der Lugt A,van der Steen AF,Ligtvoet KM

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:In China, low socioeconomic status (SES) may be a barrier for patients with coronary heart disease (CHD) to receive adequate treatment because of their inadequate access to health resources. This study aims to evaluate whether and to what extent SES is associated with the treatment of CHD patients. METHODS:...

journal_title：American heart journal

authors： Niu S,Zhao D,Zhu J,Liu J,Liu Q,Liu J,Wang W,Smith SC Jr,BRIG project.

更新日期：2009-04-01 00:00:00

abstract：:Currently available internal cardiac defibrillators use a uniphasic, truncated exponential waveform morphology of about 6 msec in duration at an energy level of 23 to 33 joules. To determine if improved defibrillation could be achieved with a different waveform morphology, we implanted 4.5 cm2 titanium patches to the ...

journal_title：American heart journal

authors： Flaker GC,Schuder JC,McDaniel WC,Stoeckle H,Dbeis M

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVES:We aim to review the studies comparing coronary calcification across different ethnic groups. BACKGROUND:There is still uncertainty regarding ethnic differences in the prevalence, progression, and risk of coronary artery disease. Clues to possible racial differences in rates of coronary heart disease (CHD) ...

journal_title：American heart journal

authors： Orakzai SH,Orakzai RH,Nasir K,Santos RD,Edmundowicz D,Budoff MJ,Blumenthal RS

更新日期：2006-11-01 00:00:00

abstract：:Polymorphic ventricular arrhythmias (PVAs) initiated by programmed electrical stimulation may be a nonspecific response or evidence of ventricular electrical instability. To determine if PVAs initiated in patients with spontaneous sustained ventricular tachycardia or fibrillation differ from those which are clearly a ...

journal_title：American heart journal

authors： Stevenson WG,Brugada P,Waldecker B,Zehender M,Wellens HJ

更新日期：1986-06-01 00:00:00

abstract：:Salient clinical, hemodynamic, angiocardiographic, and pathologic findings are presented in 100 patients with truncus arteriosus communis, 79 of whom were studied at autopsy. In this study of typical truncus, all had a ventricular septal defect (type A). Truncus with a partially formed aorticopulmonary septum (type A1...

journal_title：American heart journal

authors： Calder L,Van Praagh R,Van Praagh S,Sears WP,Corwin R,Levy A,Keith JD,Paul MH

更新日期：1976-07-01 00:00:00

abstract：:Blood platelets play essential roles in normal coagulation and in coronary atherosclerotic disease and its complications. Various antiplatelet therapies, including aspirin, ticlopidine, and dipyridamole, have been developed for use in patients with known coronary artery artery disease to prevent ischemic complications...

journal_title：American heart journal

authors： Frishman WH,Burns B,Atac B,Alturk N,Altajar B,Lerrick K

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:The optimal duration of dual antiplatelet therapy (DAPT) in acute coronary syndrome (ACS) patients treated with drug eluting stents (DES) is still under debate. Recent meta-analyses on ≤6months versus 12months DAPT suggest that bleeding rates can be reduced, without a higher rate of thrombotic complications....

journal_title：American heart journal

authors： Camaro C,Damen SA,Brouwer MA,Kedhi E,Lee SW,Verdoia M,Barbieri L,Rognoni A,van T Hof AW,Ligtenberg E,de Boer MJ,Suryapranata H,De Luca G

更新日期：2016-08-01 00:00:00

abstract：:Nitrates are widely used for the management of congestive heart failure (CHF), as well as angina pectoris. In both situations, nitrates significantly increase exercise capacity. The mechanism of this beneficial effect is unclear, especially in CHF. Isosorbide dinitrate reduces pulmonary capillary wedge pressure (PCWP)...

journal_title：American heart journal

authors： Franciosa JA

更新日期：1985-07-01 00:00:00

abstract：:Mitral valve prolapse (MVP) is a common cardiac valve abnormality that affects women more frequently than men. We have previously shown that mild dehydration induces echocardiographic signs of MVP in approximately 50% of healthy asthenic women with previously normal cardiac findings. The present study was designed to ...

journal_title：American heart journal

authors： Aufderheide S,Lax D,Goldberg SJ

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Prior studies have reported race and sex differences in cardiac catheterization use after acute myocardial infarction (AMI). It is unclear whether race or sex differences in procedure refusal may contribute to this difference. We sought to determine whether cardiac catheterization refusal rates differ by pat...

journal_title：American heart journal

authors： Rathore SS,Ordin DL,Krumholz HM

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Studies on the effect of heart failure clinics have been encouraging and convincing with respect to reduced hospitalizations, improved quality of life, and reduced cost. However, previous results have been derived from patient populations either recently discharged and with specific exclusion criteria or fro...

journal_title：American heart journal

authors： Galatius S,Gustafsson F,Nielsen PH,Atar D,Hildebrandt PR

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Peak creatine kinase (CK)-MB concentration is related to reperfusion success and clinical outcomes after fibrinolytic therapy for acute myocardial infarction. However, prognostic implications of CK-MB measurements after primary percutaneous coronary intervention (PCI), which provides more predictable and con...

journal_title：American heart journal

authors： Bagai A,Schulte PJ,Granger CB,Mahaffey KW,Christenson RH,Bell G,Lopes RD,Green CL,Lincoff AM,Armstrong PW,Roe MT

更新日期：2014-10-01 00:00:00

abstract：:Three patients with subpulmonic ventricular septal defect and pulmonary valve fluttering by echocardiography are presented. The echographic changes appear identical to that reported with infundibular pulmonic stenosis and the mechanism causing this fluttering is probably similar. ...

journal_title：American heart journal

authors： Glasser SP,Baucum RW Jr

更新日期：1977-07-01 00:00:00

abstract：:The aim of this study was to investigate whether platelet-activating factor (PAF), PAF receptors, and PAF receptor-mediated effects in the human myocardium play a role in cardiac depression during anaphylaxis or septic shock. The effects of PAF, the biologically inactive derivative lyso-PAF, and the specific PAF antag...

journal_title：American heart journal

authors： Schwinger RH,Böhm M,La Rosée K,Erdmann E

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Few data are available concerning the effects on clinical outcome and left ventricular function of abciximab administration in patients undergoing rescue percutaneous transluminal coronary angioplasty (PTCA) after failed thrombolysis for acute myocardial infarction. The aim of the study was to investigate su...

journal_title：American heart journal

authors： Petronio AS,Musumeci G,Limbruno U,De Carlo M,Baglini R,Paterni G,Grazia Delle Donne M,Caravelli P,Nardi C,Mariani M

更新日期：2002-02-01 00:00:00

abstract：:The single-dose pharmacokinetics of amiodarone have been studied in volunteer subjects given 400 mg doses by the intravenous and oral routes. The data show the compound to have a very large volume of distribution, a low total clearance, and a long and variable terminal elimination half-life. In patients the terminal e...

journal_title：American heart journal

authors： Holt DW,Tucker GT,Jackson PR,Storey GC

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:In animal models, physical activity (PA) prevents cardiac myocyte cell death. Data for PA mitigating myocyte injury in humans are limited to observational studies. Using a randomized controlled trial design, we sought to determine if introducing moderate PA to previously sedentary older adults could reduce t...

journal_title：American heart journal

authors： deFilippi CR,de Lemos JA,Newman AB,Guralnik JM,Christenson RH,Pahor M,Church T,Espeland M,Krithevsky SB,Stafford R,Seliger SL,LIFE Study Group.

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Nitroglycerin is known to augment vessel wall squeezing at the site with coronary-myocardial bridging (CMB). This study was designed to define the mechanism of nitroglycerin-induced augmentation of CMB in clinical settings. METHODS:We analyzed nitroglycerin reactivity at the site with CMB in 39 patients. Ma...

journal_title：American heart journal

authors： Hongo Y,Tada H,Ito K,Yasumura Y,Miyatake K,Yamagishi M

更新日期：1999-08-01 00:00:00

abstract：:To determine whether any differences exist in results of treatment of restenosis with repeat angioplasty when the procedure is performed during diagnosis or, as an alternative, when it is performed as a separate elective procedure, we prospectively compared the outcome of 48 consecutive procedures (including 51 lesion...

journal_title：American heart journal

authors： Alfonso F,Macaya C,Iñiguez A,Zarco P

更新日期：1990-02-01 00:00:00

abstract：:Chronic exposure to fine particulate matter (PM2.5) is accepted as a causal risk factor for coronary heart disease (CHD). However, most of the evidence for this hypothesis is based upon cohort studies in whites, comprised of either only males or females who live in urban areas. It is possible that many estimates of th...

journal_title：American heart journal

authors： Loop MS,McClure LA,Levitan EB,Al-Hamdan MZ,Crosson WL,Safford MM

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:It is unclear whether fibrinogen predicts cardiovascular events independently of echocardiographic cardiovascular abnormalities and traditional risk factors. METHODS:We studied 2671 American Indians who participated in the second Strong Heart Study examination (1993-1995) and were observed for an average of...

journal_title：American heart journal

authors： Palmieri V,Celentano A,Roman MJ,de Simone G,Best L,Lewis MR,Robbins DC,Fabsitz RR,Howard BV,Devereux RB,Strong Heart Study.

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Transcatheter aortic valve replacement (TAVR) is an effective therapeutic option for patients with severe aortic stenosis at high risk for surgery. Identification of causes of death after TAVR may help improve patient selection and outcome. METHODS:We enrolled 874 consecutive patients who underwent TAVR at ...

journal_title：American heart journal

authors： Saia F,Latib A,Ciuca C,Gasparetto V,Napodano M,Sticchi A,Anderlucci L,Marrozzini C,Naganuma T,Alfieri O,Facchin M,Hoxha B,Moretti C,Marzocchi A,Colombo A,Tarantini G

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Biolimus-eluting stents (BESs) with a biodegradable polymer in abluminal coating achieve more complete coverage at 9 months compared with sirolimus-eluting stents (SESs) with a durable polymer, as assessed by optical coherence tomography (OCT). Whether this advantage persists or augments after complete resor...

journal_title：American heart journal

authors： Gutiérrez-Chico JL,Jüni P,García-García HM,Regar E,Nüesch E,Borgia F,van der Giessen WJ,Davies S,van Geuns RJ,Secco GG,Meis S,Windecker S,Serruys PW,di Mario C

更新日期：2011-11-01 00:00:00

abstract：:Mitochondria in skeletal and cardiac muscle have been found to be less stable in aging hamsters, in contrast to preparations from young animals. We have found previously that clofibrate (Atromid-S) will reverse this degeneration in the older hamsters. This study examined the exercise tolerance of aged hamsters, to see...

journal_title：American heart journal

authors： Guntheroth WG,Inamdar AR,Person R,Mackler B

更新日期：1977-10-01 00:00:00

abstract：:Three cases of apical left ventricular hypertrophy demonstrating a sequestered small left ventricular apical cavity with complete systolic and partial diastolic intraventricular obstruction are described. Doppler studies revealed that flow from the apical chamber is aborted during early systole with further emptying d...

journal_title：American heart journal

authors： Zoghbi WA,Haichin RN,Quinones MA

更新日期：1988-12-01 00:00:00