Abstract:
:Maturational changes in visceral nociception were measured in developing or adult rats challenged with hypertonic saline or acetylcholine. Chemically induced abdominal constrictions were absent in rats younger than 7 days of age, regardless of the dose of hypertonic saline or acetylcholine used. Age-related increases in the percent of animals responding, the number of abdominal constrictions emitted per responder, and total response duration occurred in animals 10-20 days of age, until adult-like patterns of responding were attained at the time of weaning. Additional changes in the percent animals responding, as well as in the frequency and total duration of abdominal constriction responses, were also seen in postweanling, but not in preweanling, animals. Five-day-old animals did emit audible vocalizations to the intraperitoneal insertion of a hypodermic needle, however, at a time when these animals failed to show observable responses to the noxious visceral stimuli. Hence, mechanisms mediating pain associated with intraperitoneal needle insertion may be functional during the first postnatal week, at a time when mechanisms mediating visceral pain appear to be immature. These differences may be caused by the differential maturation of sensory, neural, or motoric mechanisms important for hypodermic needle insertion versus visceral nociception.
journal_name
Dev Psychobioljournal_title
Developmental psychobiologyauthors
Bronstein DM,Mitteldorf P,Sadeghi MM,Kirby K,Lytle LDdoi
10.1002/dev.420190508subject
Has Abstractpub_date
1986-09-01 00:00:00pages
473-87issue
5eissn
0012-1630issn
1098-2302journal_volume
19pub_type
杂志文章abstract::The present study was designed to investigate cocaine self-administration in adult male and female rats exposed prenatally to morphine. Pregnant dams were injected two times a day with either saline, analgesic doses of morphine or no drug at all (controls) on gestation Days 11-18. One day after birth, litters were cro...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20240
更新日期:2007-07-01 00:00:00
abstract::Delay of gratification in 3 chimpanzees (Pan troglodytes) was examined by using a paradigm based on research with children. The chimpanzees either pressed a door-bell button during a trial and received one reward (the immediate reward) or did not press the doorbell and received another reward (the delayed reward). Two...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/(sici)1098-2302(199903)34:2<119::aid-dev5>
更新日期:1999-03-01 00:00:00
abstract::The effects of neonatal undernutrition in rats on food and water regulation, external indices of development, and long-term regulatory behavior were investigated. Undernutrition produced retardation in some external indices of development. The ability to eat, drink, and maintain body weight at weaning were not serious...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420110205
更新日期:1978-03-01 00:00:00
abstract::Associations between prenatal maternal emotional complaints and child behavioral and cognitive problems have been reported, with different relations for boys and girls. Fetal programming hypotheses underline these associations and state that the early development of the HPA-axis of the children may have been affected....
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20393
更新日期:2009-11-01 00:00:00
abstract::Autism is an early onset neurodevelopmental disorder characterized by disruption of early social interaction. Although the social disability of autism remains the central defining feature of the condition, mechanisms that might account for this disability remain poorly understood. This paper briefly reviews some aspec...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.20556
更新日期:2011-07-01 00:00:00
abstract::In order to examine the effects of cannabinoids, malnutrition, and their possible interaction upon the developing rat fetus, female Wistar rats were exposed to cannabis smoke, placebo smoke, or no smoke while concurrently consuming 1 of 3 diets differing in protein concentration (8%, 24%, 64%). Both the diet and drug ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420130605
更新日期:1980-11-01 00:00:00
abstract::The stability of children's skin conductance level during baselines (SCL-B) and SCL reactivity (SCL-R) were examined longitudinally. During two laboratory sessions (T1 and T2), 2 years apart, children participated in procedures during which they were exposed to two stressors namely exposure to an audiotaped conflict b...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20171
更新日期:2007-03-01 00:00:00
abstract::Spontaneous movements of premature infants between 25 and 34 weeks conceptional age were observed for 1 hr on two or three occasions. Subjects had low-risk prognoses and were clinically stable at the time of testing. Behavioral acts were scored using a 0/1 time sampling technique in 60 continuous, 1-min time blocks. T...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420270503
更新日期:1994-07-01 00:00:00
abstract::Fourteen infant capuchins and eight squirrel monkeys reared by their mothers in captive species-typical social groups were observed from birth through 7 months. Motoric altriciality of the neonatal capuchin relative to the squirrel monkey is a key feature of behavioral differences between the species in the first few ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420240602
更新日期:1991-09-01 00:00:00
abstract::Previous work indicates that mice of different genotypes reared in enriched environments show differential increases in performance on a food-seeking task. In this study 2 experiments examined the effects in selected mice strains of short exposures to such enrichment. Experiment 1 indicated that 48 hr of exposure to e...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420090608
更新日期:1976-11-01 00:00:00
abstract::A wide variety of hypotheses have been put forth that address the functional significance of active sleep. Despite the well-accepted fact that active sleep expresses itself predominantly in the perinatal period, the vast majority of these functional hypotheses are applicable largely, if not exclusively, to the adult. ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/(SICI)1098-2302(199601)29:1<1::AID-DEV1>3.
更新日期:1996-01-01 00:00:00
abstract::In two experiments we examined the effects of human contact and vagal regulation on newborns' pain reactivity and visual attention. Baseline cardiac vagal tone was measured during quiet sleep and during the experiment, and vagal withdrawal was indexed as change in vagal tone from baseline to pain (study 1) or attentio...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20150
更新日期:2006-11-01 00:00:00
abstract::The consistent gender differences favoring males in some spatial abilities like mental rotation have raised the question of whether testosterone or other gonadal hormones contribute to these differences--especially because such gender differences seem to appear mainly from the age of puberty on. Studies generally sugg...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21333
更新日期:2016-01-01 00:00:00
abstract::Whereas significant advances have been made in understanding how exposure to early adversity "gets under the skin" of children to result in long term changes in developmental outcomes, the processes by which positive social relationships become biologically embedded remain poorly understood. The aim of this study was ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21505
更新日期:2017-05-01 00:00:00
abstract::Psychobiological convergence-the alignment of task-related changes in children's self-reported and physiological indices of reactivity-has recently emerged as a powerful correlate of children's attachment representations, but has not been explored for its association with children's self-reported attachment, with pare...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21748
更新日期:2018-12-01 00:00:00
abstract::There is very little research comparing great ape and human cognition developmentally. In the current studies we compared a cross-sectional sample of 2- to 4-year-old human children (n=48) with a large sample of chimpanzees and bonobos in the same age range (n=42, hereafter: apes) on a broad array of cognitive tasks. ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21125
更新日期:2014-04-01 00:00:00
abstract::Face processing mechanisms are tuned to specific low-level features including mid-range spatial frequencies and horizontal orientation energy. Behaviorally, adult observers are more effective at face recognition tasks when these information channels are available. Neural responses to face images also reflect these inf...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21546
更新日期:2017-11-01 00:00:00
abstract::The aim of the present study was to determine the association between prenatal stress and immune function in human adults. Peripheral blood mononuclear cells (PBMCs) from 34 healthy young women whose mothers experienced major negative life events during their pregnancy (Prenatal Stress, PS group, mean age 25, SD +/- 4...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20316
更新日期:2008-09-01 00:00:00
abstract::This study tested predictions regarding two hypothesized maternal immune responses influencing sexual orientation: one affecting homosexual males with high fraternal birth order and another affecting firstborn homosexual individuals whose mothers experience repeated miscarriage after the birth of the first child. Low ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21254
更新日期:2015-01-01 00:00:00
abstract::It has been argued that a recently developed measure, vagal tone (V), is a significant advancement over other existing methods of assessing the periodic variation in heart rate associated with respiration (respiratory sinus arrhythmia). It has been further suggested that, as a noninvasive measure of vagal nerve effere...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420240203
更新日期:1991-03-01 00:00:00
abstract::The supine nursing posture, which occurs increasingly as growing pups initiate nursing from their recumbent dam, was demonstrated to require more space than that provided in earlier studies of mother-young contact (e.g., Leon, Croskerry, & Smith, 1978). Further, hyperthermic rat pups were shown to be deficient in elic...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/(SICI)1098-2302(199603)29:2<101::AID-DEV2>
更新日期:1996-03-01 00:00:00
abstract::Environmental conditions during early development play a crucial role in shaping an organism's phenotype. To test how social group size affects stress response and behavioral characteristics, we used great tits (Parus major) from selection lines for exploratory behavior, a proxy for an avian personality trait, and bir...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20533
更新日期:2011-09-01 00:00:00
abstract::Early-life stress confers profound and lasting risk for developing cognitive, social, emotional, and physical health problems. The effects of stress on the developing brain contribute to this risk, with frontolimbic circuitry particularly susceptible to early experiences, possibly due to its innervation with glucocort...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.21969
更新日期:2020-03-29 00:00:00
abstract::In contrast to other aspects of species-specific development, language development represents both the universal thrust of biologically based capacities and the socially differentiated results of human experience in culturally structured worlds. This article presents a theoretical approach for understanding the ways t...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420230712
更新日期:1990-11-01 00:00:00
abstract::Rat pups are more resistant to retroactive associative interference 3 hr after birth than 24 hr later [Cheslock et al. [2004] Developmental Science, 7, 581-598]. The present experiments tested the effect of age, retention interval and dam presence during the retention interval on odor-induced motor activity subsequent...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20456
更新日期:2010-05-01 00:00:00
abstract::The aim of the study was to investigate parental perception and interpretation of infant emotional expression depending on their attachment representation. Forty-six parents' responses to infant pictures depicting positive, neutral, and negative emotions were assessed on the level of affective judgments (valence, arou...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20441
更新日期:2010-07-01 00:00:00
abstract::The effects of maternal deprivation on learning of social and spatial tasks were investigated in female adult rats. Pups were reared artificially and received "lickinglike" tactile stimulation (AR animals) or were reared with their mothers (MR animals). In adulthood, subjects were tested on paradigms of spatial learni...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.10131
更新日期:2003-11-01 00:00:00
abstract::Infant mice, reared with both parents were subjected to 1 of 4 different early experience contingencies at 3, 6, 9, and 12 days of age. Observation of parental behaviors following return of the pups to the nest revealed that mothers attended more to pups subjected to intermediate levels of stress, with the differences...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420110303
更新日期:1978-05-01 00:00:00
abstract::Under standard conditions involving isolation and cooling, it has been documented that intraoral infusion of milk and injection of the intestinal peptide cholecystokinin (CCK) result in an attenuation in ultrasonic vocalizations (USV) emitted by infant rat pups. One of the most effective stimuli in inhibiting ingestio...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.10019
更新日期:2002-03-01 00:00:00
abstract::Separate fields of inquiry indicate (a) that prenatal stress is associated with heightened behavioral and physiological reactivity and (b) that these postnatal phenotypes are themselves associated with increased susceptibility to both positive and negative environmental influences. Collectively, this work supports Plu...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.21816
更新日期:2019-07-01 00:00:00