Abstract:
:In order to examine the effects of cannabinoids, malnutrition, and their possible interaction upon the developing rat fetus, female Wistar rats were exposed to cannabis smoke, placebo smoke, or no smoke while concurrently consuming 1 of 3 diets differing in protein concentration (8%, 24%, 64%). Both the diet and drug treatments were administered 20 days prior to and throughout gestation. Of the 12 variables affected by the low-protein diet, 8 were significantly potentiated when undernutrition was combined with cannabis treatment. Some dependent variables that were not altered either by the low-protein diet or by cannabis inhalation were affected by the combination of treatments. These included a lengthened gestation period, an increase in occurrence of stillbirths and litter destruction, and decreased activity in the rat pups. Cannabis coupled with a standard protein diet resulted in a number of developmental indices being delayed but combining the drug with an enriched protein diet ameliorated these effects. The evidence also suggests that the administration of cannabis both before and during gestation resulted in a degree of tolerance to some aspects of the drug effects.
journal_name
Dev Psychobioljournal_title
Developmental psychobiologyauthors
Charlebois AT,Fried PAdoi
10.1002/dev.420130605subject
Has Abstractpub_date
1980-11-01 00:00:00pages
591-605issue
6eissn
0012-1630issn
1098-2302journal_volume
13pub_type
杂志文章abstract::In this review, we consider the literature on sensitive periods for language acquisition from the perspective of the stroke recovery literature treated in this Special Issue. Conceptually, the two areas of study are linked in a number of ways. For example, the fact that learning itself can set the stage for future fai...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.20626
更新日期:2012-04-01 00:00:00
abstract::Motor activity increases during development and typically peaks before reproductive maturity. Males may become more active than do females, and this sex difference in activity may be a mechanism contributing to sex-biased dispersal. The generality of the link between sex differences in activity and sex differences in ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20286
更新日期:2008-04-01 00:00:00
abstract::The present longitudinal study examined relations between respiratory sinus arrhythmia (RSA) development and social responsiveness characteristics associated with autism spectrum disorders. Group-based developmental trajectory modeling was used to characterize RSA development patterns in 106 typically developing child...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21100
更新日期:2014-04-01 00:00:00
abstract::Very-low-birth-weight infants are at much higher risk for cognitive and language delays but the nature of such deficits is not clearly understood. Given increasing rates of prematurity and infants born very-low-birth-weight, examination of mechanisms that underlie poorer developmental outcome is essential. We investig...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20278
更新日期:2008-03-01 00:00:00
abstract::To assess the effects of early postnatal undernutrition upon the developing abilities of infant and juvenile mice to acquire and retain a passive-avoidance response, we reared mice following birth in either "normally nourished" or "undernourished" conditions by maintaining litter sizes of 6 or 16, respectively. At age...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420130404
更新日期:1980-07-01 00:00:00
abstract::Behavioral and neuromorphological data have suggested at least a partial interaction between the effects of norepinephrine-depleting neonatal 6-OHDA lesions and the effects of rearing in enriched environments. The present study examined the impact of both of these early manipulations upon regional brain uptake of 14C-...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420250304
更新日期:1992-04-01 00:00:00
abstract::The effects of prenatal exposure to stress and to naltrexone on emotional behaviors were studied in CD1 mice during ontogeny and in the adulthood. During ontogeny (a) lower body weights were initially found in pups born by mothers injected with naltrexone; (b) treatments did not affect sensory motor development except...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420210309
更新日期:1988-04-01 00:00:00
abstract::Observation of cortisol and behavioral responses to routine inoculation was conducted at 18 months for infants in a longitudinal sample whose stress responses had been observed at 2, 4, and 6 months of age. At 18 months, infants showed an increase in cortisol level over base to the perturbation. The magnitude of this ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420280804
更新日期:1995-12-01 00:00:00
abstract::This study tested predictions regarding two hypothesized maternal immune responses influencing sexual orientation: one affecting homosexual males with high fraternal birth order and another affecting firstborn homosexual individuals whose mothers experience repeated miscarriage after the birth of the first child. Low ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21254
更新日期:2015-01-01 00:00:00
abstract::The reactions of 4 infants each at ages 10, 15, and 20 months were recorded on videotape as they responded to their own simultaneous video image, their own previously taped video image, the image of a control infant, and that of a female stranger. The subjects' responses were coded by 2 research assistants, ignorant o...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420100102
更新日期:1977-01-01 00:00:00
abstract::Despite evidence that acute stress impairs attention in adults, there has been minimal research in children. Here, the effects of acute stress on Go/No-go performance were examined in young children (M age = 5.41 years). Given the critical role of the parent-child relationship to children's self-regulatory development...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21915
更新日期:2020-05-01 00:00:00
abstract::Male and female rats (T rats) given an injection of 75 microgram tri-iodothyronine (T3) and 25 microgram thyroxine (T4) on Day 3 after birth were raised under enriched (E) and impoverished (I) postweaning conditions. Observations of their open-field behavior and Days 63 and 112 revealed a higher rate of activity in T ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420110410
更新日期:1978-07-01 00:00:00
abstract::The sexual development of C57BL 6/J and SEC/IReJ male mice was studied during twice-weekly pairings with estrus females from 5 weeks of age. SEC were far slower to begin copulating than C57 and their responses to the female included a much higher frequency of rooting. Rooting, where the male's snout is pushed below th...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420160406
更新日期:1983-07-01 00:00:00
abstract::The mesolimbic dopamine (DA) pathway is critical in reward-mediated behavior. Water, sucrose, and drugs of abuse all increase DA in the nucleus accumbens septi (NAcc) in adult animals. Recently our laboratory has shown that cocaine and alcohol increase DA efflux in preadolescent animals. The present study used a natur...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/1098-2302(2001)38:1<46::aid-dev4>3.0.co;2-
更新日期:2001-01-01 00:00:00
abstract::The effects of early handling on behavioral and physiological responses of the rat during active avoidance learning were investigated. Handled and nonhandled males and females were run in a 2-way shuttlebox task with an unconditioned stimulus of either .5 mA or .8 mA. Animals exposed to .8 mA showed a higher corticost...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420100209
更新日期:1977-03-01 00:00:00
abstract::Newly hatched domestic chicks were given extended free access to 7 rates of intermittent white light between .5 and 24 flashes per sec. Inspection of the data showed approaches and departures directed toward the light that increased in number and formed an orderly pattern as the rates neared 4 per sec and as the chick...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420120506
更新日期:1979-09-01 00:00:00
abstract::The characterization of adolescence as a time of "storm and stress" remains an open debate. Intense and frequent negative affect during this period has been hypothesized to explain the increased rates of affective disorders, suicide, and accidental death during this time of life. Yet some teens emerge from adolescence...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.20447
更新日期:2010-04-01 00:00:00
abstract::Spontaneous eye blinking has been studied in clinical and neuropharmacological research in adult humans and nonhuman primates as a putative index of central dopamine system activity. One purpose of this review is to provide a general overview of the research on spontaneous eye blinking with an emphasis on the relation...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.10162
更新日期:2004-03-01 00:00:00
abstract::The goal of this study was to evaluate lateral preferences in a population of children with intellectual deficiency of idiopathic origin, compared with those of typically developing (TD) children. Two groups of children with mild or moderate intellectual deficiency were observed. Handedness (using a 10-item test and B...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20167
更新日期:2006-09-01 00:00:00
abstract::To extend a previous finding that 6-month-old infants categorized low-pass filtered infant-directed (ID) utterances, we examined a) 6-month-old infants' categorization of more naturalistic, unfiltered ID utterances and b) the developmental progression of ID-speech categorization. In Experiment 1, 6-month-olds heard se...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.10093
更新日期:2003-01-01 00:00:00
abstract::Norway rats were reared either in a standard laboratory cage or in a nest constructed by the dam from newspaper strips. Growth, thermoregulatory ability, and adrenal, gonad, adipose tissue, and brain weights were measured at weaning on Day 21 postpartum. While there was no difference in growth, nest-reared animals had...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420180406
更新日期:1985-07-01 00:00:00
abstract::Investigations of maternal behavior of mothers fed a low-protein diet indicated deficits in retrieval and in the rate of nest-building. In addition, they indicated a concomitant increase in time spent with young when assessed during periods not associated with the retrieval/nest-building test session. The adrenalectom...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420100308
更新日期:1977-05-01 00:00:00
abstract::The idea of the innate and the acquired is a part of folk-biology but is also used by biologists, psychologists and cognitive scientists in their disciplines. Are they right to do so? Innateness is often defined by appealing to the role of genes in development, to the role of Darwinian evolution in shaping development...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20277
更新日期:2007-12-01 00:00:00
abstract::The aim of the study was to investigate parental perception and interpretation of infant emotional expression depending on their attachment representation. Forty-six parents' responses to infant pictures depicting positive, neutral, and negative emotions were assessed on the level of affective judgments (valence, arou...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20441
更新日期:2010-07-01 00:00:00
abstract::Many transformations that occur in adolescence are related to emotion and emotion regulation, yet very little is known about the autonomic underpinnings of these changes. The aim of the study was to document age-related differences in autonomic responses to social stress and relations to emotion regulation. Ninety-nin...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20582
更新日期:2012-03-01 00:00:00
abstract::The effect of home cage environmental stimuli on learning and the effects on retention of the presence or absence of these familiar contextual training stimuli during the retention test (Experiment 1) or during the retention interval (Experiment 2) were examined using 10-day-old rats, a multidirectional active avoidan...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420190105
更新日期:1986-01-01 00:00:00
abstract::Stimuli of the same modality tend to be organized along a "natural preference scale." This study examined the ability of six- and nine-day-old rat pups to acquire appetitive learning, when the CS was one of two differently "naturally preferred" tactile stimuli (floor textures: rug and plywood). In Experiment 1, all pu...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/(sici)1098-2302(199701)30:1<29::aid-dev3>3
更新日期:1997-01-01 00:00:00
abstract::Patterns of visual interaction in mother-infant dyadic behavior have been reported for human and nonhuman primates, including age and gender differences among rhesus macaques. Such findings are tested with data from two developmental periods (Weeks 1-8 and 21-36) on Japanese macaque mother-infant visual behavior. Rate...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420170406
更新日期:1984-07-01 00:00:00
abstract::This study examined in domestic chicks the time-course of adaptation to a new object after having established strong preferences for a previous stimulus (during the first 3 days of life). By interchanging the stimuli to which the animal was exposed, and by confining the animal exclusively with the new object for some ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420080610
更新日期:1975-11-01 00:00:00
abstract::Kittens studied from 7 days onwards revealed that the earliest age at which cardiac conditioning can be established is 30 days, after some 30 light-electric shock associations. Older kittens showed both cardiac as well as motor conditioning. Animals younger than 21 days old had no well-defined cardiac responses to the...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420140111
更新日期:1981-01-01 00:00:00