Abstract:
:The effects of early handling on behavioral and physiological responses of the rat during active avoidance learning were investigated. Handled and nonhandled males and females were run in a 2-way shuttlebox task with an unconditioned stimulus of either .5 mA or .8 mA. Animals exposed to .8 mA showed a higher corticosterone response, a shorter response latency, and increased defecation. Early handling did not affect performance of the task, however handling did alter the patterns of the plasma corticosterone response over the course of avoidance training. Handled females showed less elevation of plasma corticosterone than nonhandled females, but all females showed a decrease in corticosterone over the course of avoidance learning. All males showed the drop in corticoids if run at .5 mA shock, but only handled males showed this change at .8 mA shock.
journal_name
Dev Psychobioljournal_title
Developmental psychobiologyauthors
Weinberg J,Levine Sdoi
10.1002/dev.420100209subject
Has Abstractpub_date
1977-03-01 00:00:00pages
161-9issue
2eissn
0012-1630issn
1098-2302journal_volume
10pub_type
杂志文章abstract::The sensory processing of odorants is a dynamic process that requires plasticity at multiple levels. In the olfactory bulb (OB), inhibitory interneurons undergo lifelong replacement through a process known as adult neurogenesis. These newly born cells are incorporated in a learning-dependent fashion, a process which h...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.20546
更新日期:2012-09-01 00:00:00
abstract::Previous research on the ontogeny of sodium appetite in the rat has shown that sodium deficit first engenders sodium intake at 12 days of age, whereas direct stimulation of the brain renin--angiotensin system by intracranial injection of renin increases intake of NaCl solution as early as 3 days postnatally. Similar a...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420270305
更新日期:1994-04-01 00:00:00
abstract::Handedness is an aspect of hemispheric specialization whose pattern of expression may signal an unusual specialization that in turn, may underlie several developmental psychopathologies. It is generally believed that infant handedness is neither stable nor reliable and hence, cannot be used as an early marker of poten...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20161
更新日期:2006-09-01 00:00:00
abstract::Rodent models indicate that parenting shapes offspring outcomes by programming the hypothalamic-pituitary-adrenal axis response to stress and, ultimately, altering brain structure and function. The present study tested this hypothesis and explored possible timing-dependent associations in a longitudinal sample of chil...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21788
更新日期:2019-01-01 00:00:00
abstract::In this review, we consider the literature on sensitive periods for language acquisition from the perspective of the stroke recovery literature treated in this Special Issue. Conceptually, the two areas of study are linked in a number of ways. For example, the fact that learning itself can set the stage for future fai...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.20626
更新日期:2012-04-01 00:00:00
abstract::Autonomic reactivity was studied in individuals with fragile X syndrome (FXS), a genetic disorder partially characterized by abnormal social behavior. Relative to age-matched controls, the FXS group had faster baseline heart rate and lower amplitude respiratory sinus arrhythmia (RSA). In contrast to the typically deve...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20551
更新日期:2011-12-01 00:00:00
abstract::Succession of gut microbial community structure for newborns is highly influenced by early life factors. Many preterm infants cared for in the NICU are exposed to parent-infant separation, stress, and pain from medical care procedures. The purpose of the study was to investigate the impact of early life stress on the ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21826
更新日期:2019-07-01 00:00:00
abstract::The ontogeny of the temporal context modulation of conditioned taste aversion was studied in male Wistar rats using a palatable 1% NaCl solution. A procedure that included two saline preexposures, a single pairing saline-lithium chloride (0.15 M; 1% b.w.) either at the same or a different time of day of preexposures a...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20354
更新日期:2009-03-01 00:00:00
abstract::Eighty-six premature infants were tested to examine the effects of maternal breast milk on infant development. Infants were classified by breast-milk consumption during the hospitalization period (M = 57.4 days) into three groups: those receiving minimal (<25% of nutrition), intermediate (25-75%), and substantial (>75...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.10126
更新日期:2003-09-01 00:00:00
abstract::Psychobiological convergence-the alignment of task-related changes in children's self-reported and physiological indices of reactivity-has recently emerged as a powerful correlate of children's attachment representations, but has not been explored for its association with children's self-reported attachment, with pare...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21748
更新日期:2018-12-01 00:00:00
abstract::Contractile activity of the uterus before the onset of labor (uterine contractures) has been described in a number of species and provides a powerful source of repeated stimulation for the fetus throughout much of gestation. To understand how fetal behavior responds to this dynamic aspect of the intrauterine environme...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/(SICI)1098-2302(199612)29:8<667::AID-DEV3>
更新日期:1996-12-01 00:00:00
abstract::Brain monoaminergic neurotransmitters, such as dopamine (DA), serotonin (5-HT), and noradrenaline (NA), play crucial roles in neuronal and physiological functions, including social behaviors. Isolation housing may induce behavioral and neurochemical abnormalities in rats, although its influence on neurotransmitter lev...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.22036
更新日期:2020-09-18 00:00:00
abstract::Schizophrenia is a complex neuropsychiatric disorder characterized by hallucinations, delusions, anhedonia, flat affect and cognitive impairments. The aim of this study was to propose a prenatal treatment with ketamine, a psychedelic drug that acts as a non-competitive inhibitor of glutamate NMDA receptors, as a neuro...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21586
更新日期:2018-01-01 00:00:00
abstract::Stress influences a wide variety of outcomes including cognitive processing. In the rat, early life maternal care can influence developing offspring to affect both stress reactivity and cognitive processes in adulthood. The current study assessed if variations in early life maternal care can influence cognitive perfor...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21343
更新日期:2016-01-01 00:00:00
abstract::This third paper in a series of three related developmental trajectories of bimanual object acquisition and non-differentiated bimanual manipulation (NDBM) to patterns of role-differentiated bimanual manipulation (RDBM) development to help identify the sequence of events that might predict (and potentially facilitate)...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21383
更新日期:2016-03-01 00:00:00
abstract::Spontaneous eye blinking has been studied in clinical and neuropharmacological research in adult humans and nonhuman primates as a putative index of central dopamine system activity. One purpose of this review is to provide a general overview of the research on spontaneous eye blinking with an emphasis on the relation...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.10162
更新日期:2004-03-01 00:00:00
abstract::Despite evidence that acute stress impairs attention in adults, there has been minimal research in children. Here, the effects of acute stress on Go/No-go performance were examined in young children (M age = 5.41 years). Given the critical role of the parent-child relationship to children's self-regulatory development...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21915
更新日期:2020-05-01 00:00:00
abstract::The stability of children's skin conductance level during baselines (SCL-B) and SCL reactivity (SCL-R) were examined longitudinally. During two laboratory sessions (T1 and T2), 2 years apart, children participated in procedures during which they were exposed to two stressors namely exposure to an audiotaped conflict b...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20171
更新日期:2007-03-01 00:00:00
abstract::Infant mice, reared with both parents were subjected to 1 of 4 different early experience contingencies at 3, 6, 9, and 12 days of age. Observation of parental behaviors following return of the pups to the nest revealed that mothers attended more to pups subjected to intermediate levels of stress, with the differences...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420110303
更新日期:1978-05-01 00:00:00
abstract::Despite the increasing attention to early life adversity and its long-term consequences on health, behavior, and the etiology of neurodevelopmental disorders, our understanding of the adaptations and interventions that promote resiliency and rescue against such insults are underexplored. Specifically, investigations o...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.21775
更新日期:2019-04-01 00:00:00
abstract::MK801-induced activation of caspase-3 is developmentally regulated, peaking at postnatal day (P) 7 and decreasing with increasing postnatal age thereafter. Further, at P7, cells displaying activation of caspase-3 lack expression of calcium binding proteins (CaBPs). To further explore this relationship, we investigated...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20325
更新日期:2008-11-01 00:00:00
abstract::Severe psychological stress in the first trimester of pregnancy increases the risk of schizophrenia in the offspring. To begin to investigate the role of glucocorticoid receptors in this association, we determined the effects of the glucocorticoid dexamethasone (2 mg/kg), administered to pregnant rats on gestation day...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20419
更新日期:2010-03-01 00:00:00
abstract::Infant rat pups were exposed to a novel odor (orange or cedar) while they received tactile stimulation (stroking of the body) or were presented with odor or stroking alone. The effects of these treatments were assessed on pups' performance in a huddling test (Experiment 1 and 2) and an independent feeding test (Experi...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420190613
更新日期:1986-11-01 00:00:00
abstract::To extend a previous finding that 6-month-old infants categorized low-pass filtered infant-directed (ID) utterances, we examined a) 6-month-old infants' categorization of more naturalistic, unfiltered ID utterances and b) the developmental progression of ID-speech categorization. In Experiment 1, 6-month-olds heard se...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.10093
更新日期:2003-01-01 00:00:00
abstract::Oxytocin (OT) has an organizational effect within the central nervous system and can have long-lasting effects on the expression of social behavior. OT has recently been implicated in modulating the release of serotonin through activation of receptors in the raphe nuclei. Here we test the hypothesis that OT can have a...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20566
更新日期:2012-01-01 00:00:00
abstract::C3H/HeJ male mice, an inbred strain showing retinal degeneration (rd), and normal-eyed DBA/IJ male mice were studied in a task requiring discrimination of horizontally and vertically oriented rectangles. The apparatus was modified Yerkes discrimination apparatus. The mice were given 30 days of discrimination training,...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420090209
更新日期:1976-03-01 00:00:00
abstract::Lactating females of 2 lines of mice selectively bred for long (LS) and short (SS) ethanol-induced sleep time (a measure of alcohol tolerance) consumed either tap water or 10% ethanol in tap water on Days 2-14 postpartum. Effects of genotype and neonatal treatment on offspring open-field behavior, alcohol-induced slee...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420120303
更新日期:1979-05-01 00:00:00
abstract::Early signs of aggressive behavior toward an intruder were examined in Sprague-Dawley rats. The interactions between groups of four 24-day-old pups (2 males, 2 females) and an unfamiliar male pup from another litter were observed. Some patterns of social play were asymmetric. Compared to the playmate from the group, t...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/(sici)1098-2302(199703)30:2<165::aid-dev7>
更新日期:1997-03-01 00:00:00
abstract::Puberty marks the beginning of a period of dramatic physical, hormonal, and social change. This instability has made adolescence infamous as a time of "storm and stress" and it is well-established that stress during adolescence can be particularly damaging. However, prior stress may also shape the adolescent experienc...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21765
更新日期:2019-07-01 00:00:00
abstract::Behavioral and neuromorphological data have suggested at least a partial interaction between the effects of norepinephrine-depleting neonatal 6-OHDA lesions and the effects of rearing in enriched environments. The present study examined the impact of both of these early manipulations upon regional brain uptake of 14C-...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420250304
更新日期:1992-04-01 00:00:00