Severe neonatal pertussis treated by salbutamol.

abstract：:A four year regional screening programme to detect cystic fibrosis using measurement of immunoreactive trypsinogen is described. During this period 60 infants were diagnosed; 34 by screening, 12 born with meconium ileus, and 14 not identified by the screening assay but who presented with clinical symptoms at a later a...

journal_title：Archives of disease in childhood

authors： Roberts G,Stanfield M,Black A,Redmond A

更新日期：1988-12-01 00:00:00

abstract：AIMS:To assess the efficacy of a new regimen of intravenous atropine treatment for infantile hypertrophic pyloric stenosis (IHPS) with special reference to regression of pyloric hypertrophy. METHODS:Atropine was given intravenously at a dose of 0.01 mg/kg six times a day before feeding in 19 patients with IHPS diagnos...

journal_title：Archives of disease in childhood

authors： Kawahara H,Imura K,Nishikawa M,Yagi M,Kubota A

更新日期：2002-07-01 00:00:00

abstract：:The term Ehlers-Danlos syndrome (EDS) encompasses a group of inherited connective tissue disorders. The manifestations of EDS can be seen in skin, joints, blood vessels and internal organs and vary from mild to severe and life threatening. Each subtype is a separate and different condition. The genetic basis of many s...

journal_title：Archives of disease in childhood

authors： Sobey G

更新日期：2015-01-01 00:00:00

abstract：:Ethical considerations have long been a part of clinical decision making. However, just as doctors and healthcare professionals are being increasingly challenged about the evidence base for their practice, there is increasing focus on the ethical dimension of clinical care. ...

journal_title：Archives of disease in childhood

authors： Watson AR

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To elucidate the current situation of randomised drug trials involving the paediatric population. METHODS:Systematic review of paediatric randomised controlled trials of medicinal products published in 2007. Three major databases were searched with validated search strategies; Medline, Embase and Cochrane Ce...

journal_title：Archives of disease in childhood

authors： Aripin KN,Choonara I,Sammons HM

更新日期：2010-06-01 00:00:00

abstract：:Safe and effective paediatric pharmacotherapy requires careful evaluation of the type of drug substance, the necessary dose and the age-appropriateness of the formulation. Generally, the younger the child, the more the attention that is required. For decades, there has been a general lack of (authorised) formulations ...

journal_title：Archives of disease in childhood

authors： van Riet-Nales DA,Schobben AF,Vromans H,Egberts TC,Rademaker CM

更新日期：2016-07-01 00:00:00

abstract：:The provision of positive end expiratory pressure, via a unique portable system, in the long term management of a child with thoracic dystrophy is reported. The system uses low gas flow enabling a reduction in equipment and simplification of the circuit as compared with a standard continuous positive airways pressure ...

journal_title：Archives of disease in childhood

authors： Edees S,Moulden A,Winter RJ

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Some victims of sudden infant death syndrome (SIDS) are found with their heads covered with bedclothes, but the significance of this is uncertain. The aim of this review is to describe the prevalence of head covering, the magnitude of the risk and how far the suggested causal mechanisms agree with current ep...

journal_title：Archives of disease in childhood

authors： Blair PS,Mitchell EA,Heckstall-Smith EM,Fleming PJ

更新日期：2008-09-01 00:00:00

abstract：AIMS:To assess the impact of two paediatric intensive care unit retrieval teams on the performance of three mortality risk scoring systems: pre-ICU PRISM, PIM, and PRISM II. METHODS:A total of 928 critically ill children retrieved for intensive care from district general hospitals in the south east of England (crude m...

journal_title：Archives of disease in childhood

authors： Tibby SM,Taylor D,Festa M,Hanna S,Hatherill M,Jones G,Habibi P,Durward A,Murdoch IA

更新日期：2002-11-01 00:00:00

abstract：:Two very preterm infants (born at 29 and 25 weeks, respectively) were found to have abnormal ribs. Though this was thought unimportant at the time, it was subsequently shown to indicate that some members of their families had a dominantly inherited risk of developing skin cancer and other serious problems. ...

journal_title：Archives of disease in childhood

authors： Evans DG,Sims DG,Donnai D

更新日期：1991-10-01 00:00:00

abstract：AIM:To reduce the overall expenditure on melatonin for the local health economy by working collaboratively with the CCG's. To ensure that all paediatric patients prescribed melatonin have been clinically assessed by a specialist and the most appropriate formulation is dispensed. METHOD:Evaluation of GP melatonin presc...

journal_title：Archives of disease in childhood

authors： Haley H

更新日期：2016-09-01 00:00:00

abstract：:A 9 year old girl presented with clinical manifestations of Henoch-Schönlein syndrome and macroscopic haematuria. Laboratory investigations showed selective IgA deficiency and renal biopsy showed mesangial proliferative glomerulonephritis with diffuse granular deposits of C3 on immunofluorescence. IgA deposits were ab...

journal_title：Archives of disease in childhood

authors： Martini A,Ravelli A,Notarangelo LD,Burgio VL,Plebani A

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Clinical examination, while useful, has been shown to be insufficient as the sole screening method in infants. Ultrasound examination at 8 weeks in high risk infants is an integral part of the screening process in some units. AIMS:To show the efficiency of hip sonography in detection of developmental dyspla...

journal_title：Archives of disease in childhood

authors： Lowry CA,Donoghue VB,Murphy JF

更新日期：2005-06-01 00:00:00

abstract：:Plasma testosterone was estimated by radioimmunoassay in 60 children with disorders of sexual development before and after stimulation with human chorionic gonadotrophin (HCG). In 21 children the testosterone levels after 3 and 5 daily injections of 1000 units HCG were compared and good correlation was found between t...

journal_title：Archives of disease in childhood

authors： Grant DB,Laurance BM,Atherden SM,Ryness J

更新日期：1976-08-01 00:00:00

abstract：:After their first episode of febrile convulsions, 195 previously healthy children, aged 6--30 months, were given either diazepam or phenobarbitone for a year. Each child was assigned at random to one of the two medications: children admitted on even days were given a suppository containing 5 mg diazepam every 8 hours ...

journal_title：Archives of disease in childhood

authors： Knudsen FU,Vestermark S

更新日期：1978-08-01 00:00:00

abstract：:An intravenous glucagon test was performed in 8 children with familial constitutional short stature who were also lean. These children were randomly selected from a larger group of children with the same clinical manifestation and who had been shown to have a low insulin response to an oral glucose tolerance test and ...

journal_title：Archives of disease in childhood

authors： Karp M,Laron Z,Doron M

更新日期：1975-10-01 00:00:00

abstract：:A retrospective study was made of 30 children with Leber's amaurosis (congenital retinal blindness). 24 presented with severe visual impairment, typical ophalmological findings, and absent electroretinograms. 6 other children, though presenting with marked visual loss and absent electroetinograms were later shown to b...

journal_title：Archives of disease in childhood

authors： Vaizey MJ,Sanders MD,Wybar KC,Wilson J

更新日期：1977-05-01 00:00:00

abstract：:We report a child with Down's syndrome in whom metrorrhagia and precocious puberty revealed primary autoimmune hypothyroidism. The patient had a decreased growth velocity, exaggerated weight gain, bone age delay, and bilaterally enlarged multicystic ovaries. Delays in the diagnosis and treatment of hypothyroidism can ...

journal_title：Archives of disease in childhood

authors： Chemaitilly W,Thalassinos C,Emond S,Thibaud E

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:There is limited information on the psychosocial impact of growing up with Silver-Russell syndrome (SRS), characterised by slow growth in utero leading to short stature in adulthood. Such information could aid families in making difficult treatment decisions and guide management strategies for health professi...

journal_title：Archives of disease in childhood

authors： Ballard LM,Jenkinson E,Byrne CD,Child JC,Davies JH,Inskip H,Lokulo-Sodipe O,Mackay DJG,Wakeling EL,Temple IK,Fenwick A

更新日期：2019-01-01 00:00:00

abstract：:Delayed puberty (DP) is defined as the lack of pubertal development by an age that is 2-2.5 SDs beyond the population mean. Although it generally represents a normal variant in pubertal timing, concern that DP could be the initial presentation of a serious underlying disorder has led to a diagnostic approach that is v...

journal_title：Archives of disease in childhood

authors： Abitbol L,Zborovski S,Palmert MR

更新日期：2016-08-01 00:00:00

abstract：AIM:To produce a growth reference for British children with Williams syndrome. METHODS:The children and adults recruited into the study were all affiliated to the Williams Syndrome Foundation, a parent support group founded in 1979. They have all been shown to have a deletion of chromosome 7q11.23. One growth nurse (W...

journal_title：Archives of disease in childhood

authors： Martin ND,Smith WR,Cole TJ,Preece MA

更新日期：2007-07-01 00:00:00

abstract：:Concentrations of chorionic somatomammotrophin (hCS) in maternal plasma at the time of delivery and in placental extracts were determined by radioimmunoassay and related to neonatal growth in 111 normal pregnancies. Mean maternal plasma hCS concentration was lower in association with small-for-dates infants, defined b...

journal_title：Archives of disease in childhood

authors： Macmillian DR,Hawkins R,Collier RN

更新日期：1976-02-01 00:00:00

abstract：:Asthma has little, if any, significant effect on attained adult height. Untreated asthma results in a delay of puberty by approximately 1.3 years, and pubertal delay is likely to explain the majority of apparent growth failure in asthmatics. All currently available inhaled corticosteroids (ICS) result in growth suppre...

journal_title：Archives of disease in childhood

authors： Doull IJ

更新日期：2004-01-01 00:00:00

abstract：AIMS:To obtain information about the health and well being of 108 boys six years after their involvement with the same paedophile. METHODS:Case-control study of the health records of 93 male victims of a major episode of school based child sexual abuse and 93 matched controls. Interviews with a sample of their general...

journal_title：Archives of disease in childhood

authors： Price L,Maddocks A,Davies S,Griffiths L

更新日期：2002-03-01 00:00:00

abstract：:Moderate and severe malnutrition are endemic in much of the developing world and in association with pockets of deprivation in the developed world. The cost in terms of individual and social development is high. The principles of effective management are clearly documented. A low cost, community based treatment progra...

journal_title：Archives of disease in childhood

authors： Bredow MT,Jackson AA

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:We assessed whether maternal mental health problems increased rates for child injury during the preschool years and mid-childhood, and the extent to which associations could be accounted for by a range of potential explanatory factors. DESIGN:We analysed the UK Millennium Cohort Study, a nationally represent...

journal_title：Archives of disease in childhood

authors： Hope S,Deighton J,Micali N,Law C

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Respiratory viral infections precipitate exacerbations of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease though similar data in non-cystic fibrosis (CF) bronchiectasis are missing. Our study aimed to determine the point prevalence of viruses associated with exacerbation...

journal_title：Archives of disease in childhood

authors： Kapur N,Mackay IM,Sloots TP,Masters IB,Chang AB

更新日期：2014-08-01 00:00:00

abstract：:The concentrations of immunoglobulins (Ig) G.A.M. and E were determined in paired umbilical cord and maternal sera in 50 twin pregnancies. Mean IgG levels were higher in cord than maternal sera and in most cases the cord IgG level related more closely to that of the other twin than to either maternal level or birthwei...

journal_title：Archives of disease in childhood

authors： Bryan EM,Slavin B,Nicholson E

更新日期：1976-05-01 00:00:00

abstract：:Many children who present with these acquired impairments of communication have a clear preceding event such as an acquired brain injury from a road traffic accident. Children often respond differently in this situation to adult presentations. They may have a period of mutism when the prognosis might look poor and yet...

journal_title：Archives of disease in childhood

authors： O'Hare A

更新日期：2016-03-01 00:00:00

abstract：:To test whether early treatment could postpone the chronic colonisation of the respiratory tract with mucoid strains of Pseudomonas aeruginosa in patients with cystic fibrosis, we performed a pilot study in 28 patients aged 2 to 18 years. A two week course of azlocillin (150 mg/kg/day) and tobramycin (10 to 15 mg/kg/d...

journal_title：Archives of disease in childhood

authors： Steinkamp G,Tümmler B,Malottke R,von der Hardt H

更新日期：1989-07-01 00:00:00