当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF CARDIOLOGY期刊下所有文献 > Cardiorespiratory response to exercise before and after acute beta-adrenoreceptor blockade in nonsmokers and chronic smokers.

Cardiorespiratory response to exercise before and after acute beta-adrenoreceptor blockade in nonsmokers and chronic smokers.

Abstract：

:To evaluate the effects of chronic smoking on exercise performance we studied 5 smokers and 7 nonsmokers of comparable age and physical characteristics. The resting heart rate in smokers (75 +/- 3 beats/min; mean +/- SD) was significantly (P less than 0.01) higher than in nonsmokers (64 +/- 5). During exercise on a bicycle ergometer the heart rate remained significantly (P less than 0.01) higher in smokers than in nonsmokers. After exercise, the heart rate in nonsmokers settled to 78 +/- 9 beats/min at 10 minutes compared with 105 +/- 11 (P less than 0.01) in smokers. Oxygen consumption was similar in both groups throughout. Beta-adrenergic blockade reduced the exercise tachycardia in both groups but the heart rate for the same workload remained significantly (P less than 0.01) higher in smokers. Beta-blockade significantly reduced (P less than 0.05) oxygen consumption in nonsmokers but not in smokers who also incurred a significantly (P less than 0.05) greater oxygen debt and had higher serum lactate levels. These differences were attributed mainly to carboxyhaemoglobinaemia and partly to the effect of prolonged smoking on the heart and on intermediary metabolism.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Penny WJ,Mir MA

doi

10.1016/0167-5273(86)90034-3

subject

Has Abstract

pub_date

1986-06-01 00:00:00

pages

293-304

issue

3

eissn

0167-5273

issn

1874-1754

pii

0167-5273(86)90034-3

journal_volume

11

pub_type

临床试验,杂志文章,随机对照试验

相关文献

INTERNATIONAL JOURNAL OF CARDIOLOGY文献大全
  • Long-term outcome of prosthesis-patient mismatch after transcatheter aortic valve replacement.

    abstract：BACKGROUND:Incidence and long-term clinical consequences of prosthesis-patient mismatch (PPM) after transcatheter aortic valve replacement (TAVR) are still unclear. METHODS:We enrolled 710 consecutive patients who underwent TAVR. PPM was defined as absent if the index orifice area (iEOA) was >0.85 cm2/m2, moderate if ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.06.033

    authors： Compagnone M,Marchetti G,Taglieri N,Ghetti G,Bruno AG,Orzalkiewicz M,Marrozzini C,Bacchi Reggiani ML,Palmerini T,Galiè N,Saia F

    更新日期：2020-11-01 00:00:00

  • Long-term use of angiotensin II receptor blockers and risk of cancer: a population-based cohort analysis.

    abstract：BACKGROUND:The risk of incident cancer after angiotensin II receptor blockers (ARBs) exposure was controversially reported by analyses of clinical trials and database. We assessed the occurrence of overall and site-specific cancers among ARB users and nonusers in the cohort with indications for ARB treatment. METHODS:...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2012.05.096

    authors： Wang KL,Liu CJ,Chao TF,Huang CM,Wu CH,Chen TJ,Chiang CE

    更新日期：2013-09-01 00:00:00

  • Oral anticoagulation and cardiovascular outcomes in patients with atrial fibrillation and chronic kidney disease in Asian Population, Data from the COOL-AF Thailand registry.

    abstract：BACKGROUND AND OBJECTIVES:Patients with AF and chronic kidney disease(CKD) encountered increased risks of stroke, bleeding, morbidity, and overall mortality. Oral anticoagulation in these populations definitely enhances major bleeding but the benefit of stroke reduction remained inconclusive.The aim of this study is to...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.08.068

    authors： Chantrarat T,Krittayaphong R

    更新日期：2021-01-15 00:00:00

  • Formation of a left atrial ball thrombus from a large mural thrombus 4 days after an embolic episode.

    abstract：:We present a case of basilar artery embolism originating from a left atrial mural thrombus. The thrombus was large and attached to the posterior left atrial wall, but decreased in size and detached forming a ball type thrombus over the next 4 days without anticoagulant and/or antifibrinolytic therapy. ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/s0167-5273(99)00053-4

    authors： Iga K,Izumi C,Konishi T

    更新日期：1999-07-01 00:00:00

  • Impaired baroreflex as a cause of chronotropic incompetence during exercise via autonomic mechanism in patients with heart disease.

    abstract：PURPOSE:It is thought that the mechanisms responsible for impaired chronotropic response to exercise are related to disturbance of cardiovascular autonomic regulation such as the baroreflex. However, it is still unclear whether the baroreflex mechanisms modulate heart rate (HR) responses to exercise via vagal and/or sy...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2003.12.007

    authors： Fukuma N,Oikawa K,Aisu N,Kato K,Kimura-Kato YK,Tuchida T,Mabuchi K,Takano T

    更新日期：2004-12-01 00:00:00

  • Simple electrocardiographic markers for the prediction of paroxysmal atrial fibrillation in hyperthyroidism.

    abstract：BACKGROUND:Hyperthyroidism is a major cause of paroxysmal atrial fibrillation (AF). The purpose of this study was to evaluate the predictors of AF in the patients with clinical and subclinical hyperthyroidism. METHODS AND RESULTS:The study population consisted of four groups: group I (57 euthyroid healthy persons), gr...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2003.11.040

    authors： Aras D,Maden O,Ozdemir O,Aras S,Topaloglu S,Yetkin E,Demir AD,Soylu MO,Erdogan MF,Kisacik HL,Korkmaz S

    更新日期：2005-03-10 00:00:00

  • Strategies for the prevention of acute mountain sickness and treatment for large groups making a rapid ascent in China.

    abstract：:Approximately 26.8% of China's land area has an elevation of 3000 m above sea level or higher. Because of recent demands for economic development and new construction in highland areas, many people have relocated from the plains to high plateau regions and have to face the possibility of contracting acute mountain sic...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijcard.2013.08.059

    authors： Luo Y,Yang X,Gao Y

    更新日期：2013-10-30 00:00:00

  • Prasugrel as opposed to clopidogrel improves endothelial nitric oxide bioavailability and reduces platelet-leukocyte interaction in patients with unstable angina pectoris: A randomized controlled trial.

    abstract：BACKGROUND:Platelet inhibition has been linked to improved endothelial function, a prognostic factor in coronary artery disease. Whether prasugrel, a potent platelet inhibitor, affects endothelial function remains unknown. METHODS:This was a double-blind, randomized, active-controlled, parallel trial. Patients with un...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ijcard.2017.06.099

    authors： Rudolph TK,Fuchs A,Klinke A,Schlichting A,Friedrichs K,Hellmich M,Mollenhauer M,Schwedhelm E,Baldus S,Rudolph V

    更新日期：2017-12-01 00:00:00

  • An unusual cause of fatal pulmonary embolism.

    abstract：:We report on a case of a fatal pulmonary embolism--an unexpected finding at autopsy of a 71-year-old man who had suffered from severe erosive gouty arthritis. Using morphological findings, medical history and histopathological results, we show the potentially devastating complications of this fairly common medical con...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2005.11.093

    authors： De Giorgio F,Abbate A,Zoccai GB,Pascali VL,d'Aloja E,Capelli A,Arena V

    更新日期：2007-01-18 00:00:00

  • Non-bleeding side effects of clopidogrel: have large multi-center clinical trials underestimated their incidence?

    abstract：:Large multi-center clinical trials have indicated significant clinical benefits for patients with atherosclerotic vascular diseases receiving clopidogrel therapy. Clopidogrel efficacy has been proven in cardiac and extracardiac vascular diseases. Thus, the popularity of using clopidogrel is likely to increase in the n...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2006.05.058

    authors： Almsherqi ZA,McLachlan CS,Sharef SM

    更新日期：2007-05-02 00:00:00

  • Isolated interrupted aortic arch: in a 40-year-old adult.

    abstract：:Interrupted aortic arch (IAA) is a scarce and generally lethal congenital malformation. Patients with complete IAA scarcely reach adult age without previous surgical intervention. In this case, we presented a 40-year-old isolated IAA case with hypertension and angina pectoris. IAA just distal to left subclavian artery...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2008.06.059

    authors： Gokce M,Kiriş A,Karakoç G,Kosucu P,Pulathan Z

    更新日期：2010-02-04 00:00:00

  • Metoprolol in acute myocardial infarction reduces ventricular arrhythmias both in the early stage and after the acute event.

    abstract：:Fifty three of the 5778 patients included in the MIAMI (Metoprolol in Acute Myocardial Infarction) trial were investigated with long-term ECG recordings in order to evaluate the effect of acute beta-blockade on premature ventricular complexes in and after acute myocardial infarction. Twenty five patients were given pl...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0167-5273(87)90335-4

    authors： Rehnqvist N,Olsson G,Erhardt L,Ekman AM

    更新日期：1987-06-01 00:00:00

  • Pulmonary hypertension in rheumatoid arthritis--relation with the duration of the disease.

    abstract：:Isolated pulmonary hypertension with clinical implication is rare in rheumatoid arthritis. We sought to study the prevalence of pulmonary arterial hypertension in an unselected population of 45 patients with rheumatoid arthritis (classified according to the ARA criteria) without cardiac disease and corresponding age a...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2007.04.084

    authors： Udayakumar N,Venkatesan S,Rajendiran C

    更新日期：2008-07-21 00:00:00

  • Skeletal muscle proteins oxidation in chronic right heart failure in rats: can different beta-blockers prevent it to the same degree?

    abstract：BACKGROUND:Skeletal muscle atrophy and decreased expression of slow fibers contribute to exercise capacity limitation in Chronic Heart Failure (CHF). Pro-inflammatory cytokines and free radicals worsen muscle damage. In CHF sarcomeric proteins are oxidized with reduction of muscle twitch efficiency, and VO(2)-max. Beta...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2009.02.012

    authors： Dalla Libera L,Ravara B,Gobbo V,Betto DD,Germinario E,Angelini A,Evangelista S,Vescovo G

    更新日期：2010-08-20 00:00:00

  • Pulmonary pressure-flow relation as a determinant factor of exercise capacity and symptoms in patients with regurgitant valvular heart disease.

    abstract：BACKGROUND:Exertional dyspnea is a frequent limiting symptom in patients with chronic heart failure. Furthermore, dyspnea and a plateau in VO(2) (oxygen consumption) at peak exercise often co-exist in chronic heart failure, especially in patients with severe regurgitant valvular heart disease (RVHD), their relevance to...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2004.02.015

    authors： Hasuda T,Okano Y,Yoshioka T,Nakanishi N,Shimizu M

    更新日期：2005-03-30 00:00:00

  • Comparison of various methods for quantitative evaluation of myocardial infarct volume from magnetic resonance delayed enhancement data.

    abstract：BACKGROUND:Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) enables the estimation of myocardial infarct (MI) extent. Nevertheless, manual quantification is time consuming and subjective. We sought to assess MI volume with different quantitative methods in both acute (AMI) and chronic MI (CMI)....

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2012.03.056

    authors： Baron N,Kachenoura N,Cluzel P,Frouin F,Herment A,Grenier P,Montalescot G,Beygui F

    更新日期：2013-08-10 00:00:00

  • Participation of mitochondrial permeability transition pore in the effects of ischemic preconditioning in hypertrophied hearts: role of NO and mitoKATP.

    abstract：BACKGROUND:The mitochondrial permeability transition pore (mPTP) plays an important role in ischemia-reperfusion in normotensive animals. Our study aims to define their participation in the ischemic preconditioning (IP) in hypertrophied hearts and to assess the role played by NO and mitochondrial ATP-dependent K channe...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2011.10.103

    authors： Fantinelli JC,Pérez Núñez IA,González Arbeláez LF,Schinella GR,Mosca SM

    更新日期：2013-06-05 00:00:00

  • Prolonged intra-aortic balloon pump support in biventricular heart failure induces right ventricular reverse remodeling.

    abstract：BACKGROUND:Right ventricular dysfunction is associated with high morbidity and mortality in candidates for left ventricular assist device (LVAD) implantation or cardiac transplantation. METHODS:We examined the effects of prolonged intra-aortic balloon pump (IABP) support on right ventricular, renal and hepatic functio...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.ijcard.2015.05.014

    authors： Ntalianis A,Kapelios CJ,Kanakakis J,Repasos E,Pantsios C,Nana E,Kontogiannis C,Malliaras K,Tsamatsoulis M,Kaldara E,Charitos C,Nanas JN

    更新日期：2015-08-01 00:00:00

  • Cardiac inotropic and hypertrophic effects of Nigella sativa supplementation in rats.

    abstract：:The intrinsic cardiac responses to 2-months Nigella sativa (black seed) oral supplementation (800 mg/kg) in rats were investigated. The isolated hearts were perfused in a Langendorff preparation to demonstrate the effects of N. sativa on the baseline inotropic and chronotropic functions and the myocardial flow rate. N...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2007.07.075

    authors： El-Bahai MN,Al-Hariri MT,Yar T,Bamosa AO

    更新日期：2009-01-24 00:00:00

  • The Fuster-CNIC-Ferrer Cardiovascular Polypill: a polypill for secondary cardiovascular prevention.

    abstract：:During the last decade, there has been a tremendous effort to develop different cardiovascular polypills in response to the upsurge in global cardiovascular disease worldwide. The pharmacological development of such a strategy has proven to be extremely complex from a formulation standpoint. Not all drugs are suitable...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/S0167-5273(15)31028-7

    authors： Tamargo J,Castellano JM,Fuster V

    更新日期：2015-12-01 00:00:00

  • Noninvasive biomagnetic imaging in coronary artery disease based on individual current density maps of the heart.

    abstract：OBJECTIVE:In this paper we present an attempt at noninvasive imaging of distributed myocardial electrical activity in patients suffering from myocardial infarction and in healthy subjects. Although advances have been made, noninvasive three-dimensional imaging of cardiac electrophysiological activity is still in its in...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0167-5273(97)00326-4

    authors： Leder U,Pohl HP,Michaelsen S,Fritschi T,Huck M,Eichhorn J,Müller S,Nowak H

    更新日期：1998-03-13 00:00:00

  • Do calcium-channel blockers and glucocorticoids impair no production in ischaemic heart disease patients?

    abstract：:Calcium channel blockers, as glucocorticoids, may impair generation of NO in vivo, because of urinary nitrates deficit in spite of nitrated derivatives treatment in ischaemic heart disease patients. ...

    journal_title：International journal of cardiology

    pub_type： 临床试验,评论,信件

    doi：10.1016/s0167-5273(97)00204-0

    authors： Giroux M,Ferrières J,Salles JP

    更新日期：1997-11-20 00:00:00

  • Conversion efficacy of intravenous ibutilide compared with intravenous amiodarone in patients with recent-onset atrial fibrillation and atrial flutter.

    abstract：AIM:The aim of our study was to compare the efficacy and safety of ibutilide and amiodarone (intravenously) in converting recent-onset atrial fibrillation (AF) and atrial flutter (Af) to sinus rhythm (SR). METHODS:The study was prospective, randomized and included 152 (103 men and 49 women) consecutive patients with A...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ijcard.2006.07.017

    authors： Kafkas NV,Patsilinakos SP,Mertzanos GA,Papageorgiou KI,Chaveles JI,Dagadaki OK,Kelesidis KM

    更新日期：2007-06-12 00:00:00

  • Prognostic power of NT-proBNP in left ventricular non-compaction cardiomyopathy.

    abstract：BACKGROUND:The risk of adverse events in patients with left ventricular non-compaction cardiomyopathy (LVNC) is substantial. This study was designed to determine the prognostic value of NT-proBNP, left ventricular ejection fraction (LVEF), NYHA class, and exercise capacity in LVNC patients. METHODS:Cox regression anal...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2017.02.064

    authors： Stämpfli SF,Erhart L,Hagenbuch N,Stähli BE,Gruner C,Greutmann M,Niemann M,Kaufmann BA,Jenni R,Held L,Tanner FC

    更新日期：2017-06-01 00:00:00

  • Cycle-ergometry stress testing and use of chronotropic reserve adjustment of ST depression for identification of significant coronary artery disease in clinical practice.

    abstract：:Diagnostic reliability of indexations of peak exercise ST segment depression (DeltaST) for heart rate reserve (HRi) or chronotropic reserve (CR) to identify significant coronary artery disease (CAD) by cycle-ergometer exercise testing has not been evaluated previously. Exercise testing by upright cycle-ergometer (25 W...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2007.04.035

    authors： Palmieri V,Pezzullo S,Arezzi E,D'Andrea C,Cassese S,Martino S,Celentano A

    更新日期：2008-07-21 00:00:00

  • Frequency, predictors and outcome of stent fracture after sirolimus-eluting stent implantation.

    abstract：BACKGROUND:Recently, stent fracture (SF) of sirolimus-eluting stents (SES) has been shown to be associated with an increased risk of in-stent restenosis. We sought to evaluate the incidence, predictors and clinical outcome of SF after SES implantation in comparable unselected lesions. METHODS:A total of 430 lesions of...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2007.12.067

    authors： Umeda H,Gochi T,Iwase M,Izawa H,Shimizu T,Ishiki R,Inagaki H,Toyama J,Yokota M,Murohara T

    更新日期：2009-04-17 00:00:00

  • Transcatheter leadless cardiac pacing: The new alternative solution.

    abstract：INTRODUCTION:A lack of information about the feasibility and safety of leadless pacemaker (LPMs) exists in a fragile population of patients with limited venous anatomy access or conventional pacemaker (PM) contraindication. Accordingly, the goal of this prospective observational study was to report our experience with ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.11.196

    authors： Da Costa A,Axiotis A,Romeyer-Bouchard C,Abdellaoui L,Afif Z,Guichard JB,Gerbay A,Isaaz K

    更新日期：2017-01-15 00:00:00

  • Effects of amlodipine and lacidipine on heart rate variability in hypertensive patients with stable angina pectoris and isolated left ventricular diastolic dysfunction.

    abstract：OBJECTIVE:To estimate the influence of therapy with amlodipine (A) or lacidipine (L) on heart rate variability (HRV) time and frequency domain parameters in hypertensive patients with stable angina pectoris and isolated left ventricular diastolic dysfunction. METHODS:After a 1-week washout period, the patients were ra...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.ijcard.2004.03.040

    authors： Zaliūnas R,Brazdzionyte J,Zabiela V,Jurkevicius R

    更新日期：2005-06-08 00:00:00

  • Statins attenuate but do not eliminate the reverse epidemiology of total serum cholesterol in patients with non-ischemic chronic heart failure.

    abstract：BACKGROUND:In patients with chronic heart failure (CHF) increasing levels of total serum cholesterol are associated with improved survival - while statin usage is not. The impact of statin treatment on the "reverse epidemiology" of cholesterol is unclear. METHODS:2992 consecutive patients with non-ischemic CHF due to ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2017.03.028

    authors： Fröhlich H,Raman N,Täger T,Schellberg D,Goode KM,Kazmi S,Grundtvig M,Hole T,Cleland JGF,Katus HA,Agewall S,Clark AL,Atar D,Frankenstein L

    更新日期：2017-07-01 00:00:00

  • Cardioprotective effect of atorvastatin alone or in combination with remote ischemic preconditioning on the biochemical changes induced by ischemic/reperfusion injury in a mutual prospective study with a clinical and experimental animal arm.

    abstract：BACKGROUND:Atorvastatin and remote ischemic preconditioning (RIPC) have beneficial cardiovascular protective effects. The aim of the study was to investigate possible effect of this drug alone and in combination with RIPC on the biochemical changes induced by ischemic/reperfusion injury (I/R) in a combined study with a...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.07.178

    authors： El Desoky ES,Hassan AKM,Salem SY,Fadil SA,Taha AF

    更新日期：2016-11-01 00:00:00