当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF CARDIOLOGY期刊下所有文献 > Cardiac inotropic and hypertrophic effects of Nigella sativa supplementation in rats.

Cardiac inotropic and hypertrophic effects of Nigella sativa supplementation in rats.

Abstract：

:The intrinsic cardiac responses to 2-months Nigella sativa (black seed) oral supplementation (800 mg/kg) in rats were investigated. The isolated hearts were perfused in a Langendorff preparation to demonstrate the effects of N. sativa on the baseline inotropic and chronotropic functions and the myocardial flow rate. N. sativa supplementation induced moderate global (homogenous) cardiac hypertrophy, evident by significant increases in left ventricular and whole heart weights as well as the relative heart weight/body weight ratio. The isolated perfused hearts of Nigella-treated rats showed enhanced levels of baseline peak tension, maximum rate of tension development, heart rate and myocardial flow rate. Moreover, there was a significant increase in the tension developed per gram left ventricular weight. The present study provides the first evidence of a physiological cardiac hypertrophy in rats induced by long term N. sativa supplementation.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

El-Bahai MN,Al-Hariri MT,Yar T,Bamosa AO

doi

10.1016/j.ijcard.2007.07.075

subject

Has Abstract

pub_date

2009-01-24 00:00:00

pages

e115-7

issue

3

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(07)01589-6

journal_volume

131

pub_type

信件

相关文献

INTERNATIONAL JOURNAL OF CARDIOLOGY文献大全
  • Ergonovine provocative test in Caucasian patients with left ventricular apical ballooning syndrome.

    abstract：:Of a series of 346 consecutive patients with chest pain and no significant coronary stenosis studied with ergonovine provocative test (EPT), 18 fulfilled diagnostic criteria for left ventricular apical ballooning syndrome (LVABS). EPT was negative in all these patients. On the other 328 patients, EPT was positive in 6...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2009.05.040

    authors： Martínez-Sellés M,Datino T,Pello AM,Fernández-Avilés F

    更新日期：2010-11-05 00:00:00

  • Heat shock protein inducer modifies arrhythmogenic substrate and inhibits atrial fibrillation in the failing heart.

    abstract：BACKGROUND:Geranylgeranylacetone (GGA) has been reported up-regulating heat shock protein (HSP) expression, and protecting against atrial remodeling. This study aimed to investigate the effects of GGA on atrial electrophysiology and inducibility of atrial fibrillation (AF) in heart failure (HF) model. METHODS AND RESU...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2013.06.072

    authors： Chang SL,Chen YC,Hsu CP,Kao YH,Lin YK,Lai YJ,Yeh HI,Higa S,Chen SA,Chen YJ

    更新日期：2013-10-09 00:00:00

  • Prevalence of electrocardiographic ST-T changes during acute ischemic stroke in patients without known ischemic heart disease.

    abstract：:We evaluated characteristics and prevalence of ST-segment depression and/or T-wave inversion in the resting electrocardiogram of 244 consecutive patients with acute ischemic stroke, but without ischemic heart disease. The prevalence of ST-T changes ranged from 13% to 16% and this is what to expect in the background po...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2007.05.055

    authors： Jensen JK,Bak S,Flemming Høilund-Carlsen P,Mickley H

    更新日期：2008-08-01 00:00:00

  • Comparison of short-term clinical outcomes between ticagrelor versus clopidogrel in patients with acute myocardial infarction undergoing successful revascularization; from Korea Acute Myocardial Infarction Registry-National Institute of Health.

    abstract：BACKGROUND:Although ticagrelor has been well-known to improve clinical outcomes in patients with acute myocardial infarction (AMI) without increased bleeding risk, its clinical impacts have not been well established in East Asian patients. METHODS:Between November 2011 and June 2015, a total of 8010 patients (1377 pat...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.04.044

    authors： Park KH,Jeong MH,Ahn Y,Ahn TH,Seung KB,Oh DJ,Choi DJ,Kim HS,Gwon HC,Seong IW,Hwang KK,Chae SC,Kim KB,Kim YJ,Cha KS,Oh SK,Chae JK,KAMIR-NIH registry investigators.

    更新日期：2016-07-15 00:00:00

  • A strategic approach to transcatheter closure of patent ductus: Gianturco coils for small-to-moderate ductus and Amplatzer duct occluder for large ductus.

    abstract：OBJECTIVE:To investigate the effectiveness of the strategy of transcatheter occlusion with the Gianturco coil for small-to-moderate sized ductus and with Amplatzer duct occluder (ADO) for large ductus. PATIENT AND METHODS:For ductus closure, the following strategy was applied: ADO was used in large ductus: infants and...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2004.09.021

    authors： Wang JK,Hwang JJ,Chiang FT,Wu MH,Lin MT,Lee WL,Lue HC

    更新日期：2006-01-04 00:00:00

  • Comprehensive recognition of double-site dynamic obstruction in hypertrophic cardiomyopathy by cardiac magnetic resonance and Doppler echocardiography.

    abstract：:The noninvasive assessment of the mechanisms that lead to left ventricular outflow obstruction in hypertrophic cardiomyopathy allows the correct clinical management and the most suitable medical or surgical treatment for these patients. We report the case of a male patient affected by hypertrophic obstructive cardiomy...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2007.04.154

    authors： Di Bella G,Coglitore S,Recupero A,Pugliatti P,Minutoli F,Patanè S,Bottari A,de Gregorio C

    更新日期：2007-09-14 00:00:00

  • Quinidine-induced torsade de pointes suppressed by paroxysmal atrial fibrillation.

    abstract：:A 74-year-old patient is presented in whom quinidine-induced torsade de pointes was abolished by the onset of atrial fibrillation with a fast ventricular response. Heart rate acceleration during atrial fibrillation shortened the Q-T interval from 0.68 on admission to 0.44 milliseconds when sinus rhythm was re-establis...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(87)90157-4

    authors： Maisuls E,Lorber A

    更新日期：1987-09-01 00:00:00

  • Combined baseline and one-month changes in big endothelin-1 and brain natriuretic peptide plasma concentrations predict clinical outcomes in patients with left ventricular dysfunction after acute myocardial infarction: Insights from the Eplerenone Post-Ac

    abstract：OBJECTIVE:Increased levels of neuro-hormonal biomarkers predict poor prognosis in patients with acute myocardial infarction (AMI) complicated by left ventricular systolic dysfunction (LVSD). The predictive value of repeated (one-month interval) brain natriuretic peptides (BNP) and big-endothelin 1 (BigET-1) measurement...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ijcard.2017.02.018

    authors： Olivier A,Girerd N,Michel JB,Ketelslegers JM,Fay R,Vincent J,Bramlage P,Pitt B,Zannad F,Rossignol P,EPHESUS Investigators.

    更新日期：2017-08-15 00:00:00

  • Mild therapeutic hypothermia after cardiac arrest and the risk of bleeding in patients with acute myocardial infarction.

    abstract：BACKGROUND:The aim of the study was to report the impact of our hypothermia protocol on survival and neurological outcome. Furthermore, we were interested in the risk of bleeding complications in patients with acute myocardial infarction (AMI) being treated with percutaneous coronary revascularisation (PCI) and therape...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2007.12.008

    authors： Schefold JC,Storm C,Joerres A,Hasper D

    更新日期：2009-03-06 00:00:00

  • A contemporary risk model for predicting 30-day mortality following percutaneous coronary intervention in England and Wales.

    abstract：BACKGROUND:The current risk model for percutaneous coronary intervention (PCI) in the UK is based on outcomes of patients treated in a different era of interventional cardiology. This study aimed to create a new model, based on a contemporary cohort of PCI treated patients, which would: predict 30 day mortality; provid...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.02.085

    authors： McAllister KS,Ludman PF,Hulme W,de Belder MA,Stables R,Chowdhary S,Mamas MA,Sperrin M,Buchan IE,British Cardiovascular Intervention Society and the National Institute for Cardiovascular Outcomes Research.

    更新日期：2016-05-01 00:00:00

  • Magnetic resonance reveals long-term sequelae of apical ballooning syndrome.

    abstract：BACKGROUND:The presence of small areas of necrosis has been occasionally reported immediately following apical ballooning syndrome (ABS). However, their persistence at later stages and impact on long-term prognosis are currently unknown. METHODS:Twenty consecutive patients admitted for ABS between 2004 and 2007 were p...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.ijcard.2008.08.023

    authors： Bellera MN,Ortiz JT,Caralt MT,Pérez-Rodon J,Mercader J,Fernández-Gómez C,Paré C,Heras M

    更新日期：2010-02-18 00:00:00

  • Characterisation of isoform-specific tryptic peptides of rat cardiac myosin heavy chains using automated liquid chromatography-matrix assisted laser desorption ionisation (LC-MALDI) mass spectrometry.

    abstract：:Proteomics investigations using 2-dimensional electrophoresis (2-DE) cannot resolve the entire cardiac proteome because some proteins, including myosin heavy chains (MyHC), are insoluble in the buffers required for isoelectric focusing. Here, we report an automated mass spectrometry (MS) method complementary to 2-DE a...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2008.11.058

    authors： Burniston JG,Connolly JB

    更新日期：2010-04-30 00:00:00

  • Developmental considerations of mitral valve anomalies.

    abstract：:Atrioventricular valve development is described as following the general principle of junctional invagination and myocardial undermining. We have added considerations of the topographic relations of the developing mitral valve to these principles. Two groups of malformations are then distinguished: the first comprises...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(86)90202-0

    authors： Wenink AC,Gittenberger-de Groot AC,Brom AG

    更新日期：1986-04-01 00:00:00

  • Cardiomyopathy: a role for nitric oxide?

    abstract：:The negative inotropism, myocardial dilatation and cytotoxicity in inflammatory heart disorders may be due to increased generation of nitric oxide (NO) by immunological induction of a high output NO pathway. This short review discusses the initial experiments which lead to this hypothesis, and evaluates data that this...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/0167-5273(95)02386-b

    authors： de Belder A,Moncada S

    更新日期：1995-07-01 00:00:00

  • Milrinone versus dobutamine in heart failure subjects treated chronically with carvedilol.

    abstract：OBJECTIVE:To compare the efficacy of milrinone and dobutamine in patients chronically treated with carvedilol. BACKGROUND:Milrinone and dobutamine are used to manage decompensated heart failure, but their efficacy in patients on beta-blocker therapy was unknown. METHODS:Twenty patients with decompensated heart failur...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/s0167-5273(01)00520-4

    authors： Lowes BD,Tsvetkova T,Eichhorn EJ,Gilbert EM,Bristow MR

    更新日期：2001-12-01 00:00:00

  • NADPH oxidase inhibitor apocynin prevents atrial remodeling in alloxan-induced diabetic rabbits.

    abstract：OBJECTIVES:Diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF). The role of the NADPH oxidase (NOX) signaling in the setting of DM and the potential benefits of apocynin on diabetic atrial remodeling remain unknown. METHODS:Sixty Japanese rabbits were randomized into 3 groups as follows: ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.07.132

    authors： Qiu J,Zhao J,Li J,Liang X,Yang Y,Zhang Z,Zhang X,Fu H,Korantzopoulos P,Liu T,Li G

    更新日期：2016-10-15 00:00:00

  • A novel heart rate control model provides insights linking LF-HRV behavior to the open-loop gain.

    abstract：BACKGROUND:Low-frequency heart rate variability (LF-HRV) at rest has already been successfully modeled as self-sustained oscillations in a nonlinear control loop, but these models fail to simulate LF-HRV decreases either during aerobic exercise or in heart failure patients. Following control engineering practices, we a...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2012.09.073

    authors： Dvir H,Bobrovsky BZ,Gabbay U

    更新日期：2013-09-20 00:00:00

  • Transoesophageal Doppler pulmonary venous flow pattern and left atrial spontaneous contrast in mitral stenosis.

    abstract：:The relationship between transoesophageal Doppler pulmonary venous flow pattern and spontaneous left atrial contrast was studied in 23 patients with isolated severe mitral stenosis (mitral valve area = 0.8 +/- 0.2 cm2). The patients with none or minimal (1+) spontaneous contrast (n = 15, group I) were compared with th...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(92)90307-o

    authors： Jolly N,Mohan JC,Arora R

    更新日期：1992-09-01 00:00:00

  • Impact of renal function on the immediate and long-term outcomes of percutaneous recanalization of coronary chronic total occlusions: A systematic review and meta-analysis.

    abstract：BACKGROUND:Renal impairment is associated with worse in-hospital and long-term outcomes after coronary artery revascularization, yet limited evidence is available on its impact on short- and long-term outcomes after chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS:We conducted a systemat...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.05.067

    authors： Moroni F,Spangaro A,Carlino M,Baber U,Brilakis ES,Azzalini L

    更新日期：2020-10-15 00:00:00

  • Echocardiographic diagnosis of clinically silent congenital coronary artery anomalies.

    abstract：BACKGROUND:The incidence of congenital coronary anomalies is mainly derived from autopsy series and pre-participation exams in athletes. Limited data exist regarding the spectrum of coronary anomalies that can be detected in asymptomatic patients. We sought to describe echocardiographically detected congenital coronary...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2007.04.063

    authors： Lytrivi ID,Wong AH,Ko HH,Chandra S,Nielsen JC,Srivastava S,Lai WW,Parness IA

    更新日期：2008-06-06 00:00:00

  • Gene expression profiling of human atrial myocardium with atrial fibrillation by DNA microarray analysis.

    abstract：BACKGROUND:Atrial fibrillation (AF) is the most frequently encountered arrhythmia in the clinical setting. However, a comprehensive investigation of the molecular mechanism of AF has not been performed. The aim of this study was to clarify transcriptional profiling of genes modulated in the atrium of AF patients using ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2004.05.026

    authors： Ohki R,Yamamoto K,Ueno S,Mano H,Misawa Y,Fuse K,Ikeda U,Shimada K

    更新日期：2005-07-10 00:00:00

  • Melatonin metabolite 6-Sulfatoxymelatonin, Cu/Zn superoxide dismutase, oxidized LDL and malondialdehyde in unstable angina.

    abstract：BACKGROUND:Melatonin, a lypophylic antioxidant, was reported to be low in patients suffering from myocardial infarction, a disease due to coronary atherosclerosis associated with increased reactive oxygen species. Studies carried out till now have shown association of either melatonin or another antioxidant Cu/Zn SOD i...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2009.03.004

    authors： Vijayasarathy K,Shanthi Naidu K,Sastry BK

    更新日期：2010-10-08 00:00:00

  • Anomalous origin of the right coronary artery from the left anterior descending artery in a patient with single left coronary artery: a rare coronary artery anomaly and review of the literature.

    abstract：:A 44-year-old woman with hypertension was admitted because of recent onset chest pain. Coronary angiography revealed an anomalous right coronary artery originating as a separate branch from the left anterior descending artery. Associated with the present case all published case reports were thoroughly investigated and...

    journal_title：International journal of cardiology

    pub_type： 信件,评审

    doi：10.1016/j.ijcard.2007.04.121

    authors： Erdogan O,Buyuklu M,Aktoz M

    更新日期：2008-07-04 00:00:00

  • Left ventricular myocardial performance index in closely-related relatives of patients with dilated cardiomyopathy.

    abstract：:In this study, the left ventricular dimensions, systolic function, and left ventricular myocardial performance index in the first-degree relatives of the children with dilated cardiomyopathy (n=19), 30.0+/-17.6 years to normal age- and sex-matched controls (n=25), 27.4+/-17.7 years. The percentage ratio of the measure...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2006.11.246

    authors： Khositseth A,Ausayapao P

    更新日期：2008-03-14 00:00:00

  • Left atrial appendage blood flow in a case of persistent atrial standstill.

    abstract：:Persistent atrial standstill, characterized by absence of atrial activity on surface and intracavitary electrograms, absence of atrial mechanical activity, and inability to stimulate the atria electrically, is a rare disorder. Left atrial appendage blood flow has been reported to be related to P wave during sinus rhyt...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/s0167-5273(96)02794-5

    authors： Lin JM,Lin JL,Tseng YZ

    更新日期：1996-11-15 00:00:00

  • QTc interval in survivors of out of hospital cardiac arrest.

    abstract：BACKGROUND:QTc interval (QTc) prolongation is seen on the post-arrest electrocardiogram (ECG) of many out of hospital cardiac arrest (OHCA) survivors. It remains unclear whether this is a transient phenomenon or a manifestation of an underlying arrhythmic substrate. This observational study assessed the trend of QTc in...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.08.090

    authors： Anilkumar A,Moore EJ,Gall AJ,Sammut E,Barman P

    更新日期：2021-01-15 00:00:00

  • Cardiac effects of exercise rehabilitation in hemodialysis patients.

    abstract：:Exercise training has well documented beneficial effects in a variety of cardiac disorders. End stage renal disease patients present many cardiovascular complications and suffer from impaired exercise capacity. No study to date has adequately examined the cardiac responses to exercise training in renal patients on hem...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0167-5273(99)00090-x

    authors： Deligiannis A,Kouidi E,Tassoulas E,Gigis P,Tourkantonis A,Coats A

    更新日期：1999-08-31 00:00:00

  • Time dependent changes in high density lipoprotein cholesterol and cardiovascular risk.

    abstract：BACKGROUND:High-density lipoprotein cholesterol (HDL-C) is a strong inverse predictor of cardiovascular events. The aim of the current study was to evaluate the correlation between changes in HDL-C and subsequent cardiovascular events. METHODS:Study population comprised 13,037 subjects free of cardiovascular disease w...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2014.03.022

    authors： Milwidsky A,Kivity S,Kopel E,Klempfner R,Berkovitch A,Segev S,Sidi Y,Goldenberg I,Maor E

    更新日期：2014-05-01 00:00:00

  • The relation between radionuclide angiography and Doppler echocardiography during contractile changes with infusions of epinephrine.

    abstract：:To define the quantitative relations between radionuclide and Doppler measures of systole during sympathetic activation with epinephrine, 10 young normal men were studied with simultaneous radionuclide angiography and M-mode and Doppler echocardiography during graded infusions of epinephrine (10, 25 and 50 ng/kg/min f...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(91)90163-j

    authors： Johannessen KA,Cerqueira M,Veith RC,Stratton JR

    更新日期：1991-10-01 00:00:00

  • Differences in inflammatory and thrombotic markers between unstable angina and acute myocardial infarction.

    abstract：BACKGROUND:Unstable coronary syndromes are characterised by increased inflammatory process and endothelial activation. However, the underlying mechanisms of the acute coronary syndromes are still obscure. We evaluated the differences of inflammatory and thrombotic markers, at the acute phase of unstable angina (UA) and...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2006.03.011

    authors： Tousoulis D,Antoniades C,Bosinakou E,Kotsopoulou M,Tsoufis C,Marinou K,Charakida M,Stefanadi E,Vavuranakis M,Latsios G,Stefanadis C

    更新日期：2007-02-07 00:00:00