Left ventricular myocardial performance index in closely-related relatives of patients with dilated cardiomyopathy.

Abstract:

:In this study, the left ventricular dimensions, systolic function, and left ventricular myocardial performance index in the first-degree relatives of the children with dilated cardiomyopathy (n=19), 30.0+/-17.6 years to normal age- and sex-matched controls (n=25), 27.4+/-17.7 years. The percentage ratio of the measured left ventricular end-diastolic dimension to the predicted left ventricular end-diastolic dimension (109+/-9.6 vs 105+/-11.8), left ventricular shortening fraction (34.5+/-6.6 vs 37.2+/-7%), and left ventricular ejection fraction (63.2+/-9.2 vs 66.5+/-8.1%) were not significantly different in the first-degree relatives and controls, respectively. However, the left ventricular myocardial performance index was significantly greater in the first-degree relatives than in controls (0.40+/-0.11 vs 0.31+/-0.03, p=0.01). In conclusion, the left ventricular myocardial performance index may be useful in early detect familial dilated cardiomyopathy in asymptomatic first-degree relatives of children with dilated cardiomyopathy.

journal_name

Int J Cardiol

authors

Khositseth A,Ausayapao P

doi

10.1016/j.ijcard.2006.11.246

subject

Has Abstract

pub_date

2008-03-14 00:00:00

pages

375-7

issue

3

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(07)00280-X

journal_volume

124

pub_type

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