Abstract:
BACKGROUND:Melatonin, a lypophylic antioxidant, was reported to be low in patients suffering from myocardial infarction, a disease due to coronary atherosclerosis associated with increased reactive oxygen species. Studies carried out till now have shown association of either melatonin or another antioxidant Cu/Zn SOD in patients suffering from coronary artery disease but not both together. Concurrent measurement of these two parameters will reveal the relationship if any in the probable causation of the disease. METHODS:We estimated the serum malondialdeheyde, oxidized LDL, lipid profile and activity of Cu/Zn superoxide dismutase and the concentration of urinary metabolite of melatonin, 6-Sulfatoxymelatonin in 24 h urine sample collected from 21 patients suffering from unstable angina and 30 control subjects. RESULTS:A statistically significant decrease in urinary melatonin levels (p <0.05), serum Cu/Zn SOD (p <0.001) along with significant increase in serum oxidized LDL (p <0.001), serum malondialdeheyde (p <0.01) were observed in patients compared to controls. CONCLUSION:Our observations indicate that a decreased excretion of 6-Sulfatoxymelatonin may be causally related to a decrease in serum Cu/Zn SOD, an antioxidant, with a consequent increase in serum oxidized LDL, malondialdehyde contributing to the occurrence of the disease.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Vijayasarathy K,Shanthi Naidu K,Sastry BKdoi
10.1016/j.ijcard.2009.03.004subject
Has Abstractpub_date
2010-10-08 00:00:00pages
315-7issue
2eissn
0167-5273issn
1874-1754pii
S0167-5273(09)00267-8journal_volume
144pub_type
信件abstract:BACKGROUND:Myocardial bridge (MB) has been reported to induce cardiac complications including coronary vasospasm. Although MB has some anatomical and morphological variations, the association of these variations with vasospasm is unclear. The aim of this study was to investigate the relation between morphological sever...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.07.002
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:While only few data exist correlating cardiovascular risk factors with volumetric measurements of coronary atheroma burden in patients with coronary artery disease, a recent report using intravascular ultrasound (IVUS) demonstrated independent predictors of atherosclerotic burden in a native coronary artery ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.11.194
更新日期:2008-02-20 00:00:00
abstract:BACKGROUND:To contribute to the protocol development of exercise training in LVAD supported patients by reviewing the exercise programs for those patients in the ESC affiliated countries. METHODS:A subset of data from 77 (26 countries) LVAD implanting centers that participated in the Extra-HF survey (170 centers) was ...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2015-12-15 00:00:00
abstract:BACKGROUND:Cardiopulmonary exercise testing (CPX) clearly holds prognostic value in the heart failure (HF) population. Studies investigating the prognostic value of CPX in individuals with HF have consistently examined predominantly male groups. The purpose of the present study was to examine the prognostic value of CP...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2005.11.105
更新日期:2006-11-18 00:00:00
abstract:BACKGROUND:Today, percutaneous or surgical closure of atrial septal defects (ASD) in adults are considered effective and safe treatments. However, some cases of severe left ventricular dysfunction after ASD closure were observed. This study aims at identifying predictors for prolonged intensive care unit stay, and post...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2007.02.022
更新日期:2008-03-28 00:00:00
abstract:BACKGROUND:The clinical characteristics and prognostic value of early repolarization (ER) in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) and symptomatic ventricular arrhythmias remain unclear. We investigated the prevalence, clinical features, and cardiovascular outcomes of patients...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.06.007
更新日期:2015-10-15 00:00:00
abstract:AIM:The aim of our study was to compare the efficacy and safety of ibutilide and amiodarone (intravenously) in converting recent-onset atrial fibrillation (AF) and atrial flutter (Af) to sinus rhythm (SR). METHODS:The study was prospective, randomized and included 152 (103 men and 49 women) consecutive patients with A...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2006.07.017
更新日期:2007-06-12 00:00:00
abstract:BACKGROUND:Atrial electrophysiological abnormalities have previously been reported in Brugada syndrome. We investigated the incidence and electrocardiographic predictors of atrial fibrillation (AF) in a Chinese cohort of Brugada syndrome patients. METHODS:A retrospective study of Brugada syndrome patients admitted to ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2020.05.007
更新日期:2020-09-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2019.04.057
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Ischemic mitral regurgitation (IMR) is a common complication of coronary artery disease and represents an independent predictor of mortality. In the IMR the pattern of mitral valve annular dilatation is asymmetrical: this can explain the long-term incidence of recurrent mitral regurgitation after surgical an...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.07.230
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Myoglobin, cardiac troponin-T and creatine phosphokinase are biochemical indicators of acute coronary syndromes, however, the clinical significance in myocardial ischemia is not well established. Our aim was to elucidate their release kinetics in a well-defined short-lasting myocardial ischemia. METHODS:A c...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2003.12.010
更新日期:2005-02-15 00:00:00
abstract::Eight children, age between 4.5 and 19 years were treated with moricizine for supraventricular tachycardia during the last 3 years. The tachycardia was documented by surface electrocardiogram (ECG), and/or by ambulatory ECG in all the children and the mechanism of tachycardia was determined by previously published sur...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(96)02763-5
更新日期:1996-11-15 00:00:00
abstract:BACKGROUND:At present, the estimation of rest heart rate (HR) in atrial fibrillation (AF) is obtained by apical auscultation for 1min or on the surface electrocardiogram (ECG) by multiplying the number of RR intervals on the 10second recording by six. But the reasonability of 10second ECG recording is controversial. M...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.04.139
更新日期:2016-07-15 00:00:00
abstract::Cross-sectional and Doppler echocardiographic characteristics of infective endocarditis are described in six cases following patch closure of a ventricular septal defect. The patients presented to us with fever one to five months after surgery. Five of them also had congestive cardiac failure. Cross-sectional echocard...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(89)90158-7
更新日期:1989-10-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2008.11.034
更新日期:2009-04-17 00:00:00
abstract:BACKGROUND:Perioperative administration of Enoximone has been shown to improve hemodynamics, organ function, and inflammatory response. Aim of the present study was to evaluate the effects of Enoximone after on-pump cardiac surgery. METHODS:A protocol for a multicenter observational study was reviewed and approved by ...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2018.07.071
更新日期:2018-10-15 00:00:00
abstract::Information concerning acute myocardial infarction after cannabis usage is limited and the actual mechanism of cannabis-induced myocardial infarction is not well known. In the report, we described a young man with an acute myocardial infarction and cannabis-induced coronary thrombosis. ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.08.012
更新日期:2007-09-03 00:00:00
abstract::The purpose of this paper is to provide an overview of the life of the physician and theologian Michael Servetus and to discuss his analysis of the pulmonary circulation. Writers have praised Servetus for his commitment to educating his colleagues about what he heralded as the truth, and criticized him for his perceiv...
journal_title:International journal of cardiology
pub_type: 传,历史文章,杂志文章
doi:10.1016/j.ijcard.2012.06.046
更新日期:2013-07-31 00:00:00
abstract::Cardiovascular disease (CVD) contributes greatly to inequalities in health in Europe. The acute myocardial infarction (MI) in hospital death rate in Bosnia and Herzegovina is three fold higher than in European Union countries before the enlargement in 2004. There is also a striking difference in mortality between Bosn...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.06.224
更新日期:2016-08-01 00:00:00
abstract::We compared the specificity of exercise electrocardiography in 1880 men and 1818 women with women grouped by menopausal and estrogen replacement status. Specificity for > or = 1 mm horizontal or downsloping ST-segment depression was determined using angiography in 781 patients and using two other nonangiography-based ...
journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:1997-06-27 00:00:00
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journal_title:International journal of cardiology
pub_type: 评论,信件
doi:10.1016/j.ijcard.2008.04.005
更新日期:2009-05-29 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:1988-03-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2013.03.051
更新日期:2013-10-03 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia. In developing countries, AF is a growing public health problem with the epidemiologic transition from communicable to non-communicable diseases. However, relatively little is known about AF in the developing world. The aim of this review...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2013.01.184
更新日期:2013-09-10 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2006.02.020
更新日期:2007-03-20 00:00:00
abstract:BACKGROUND:P2Y12-ADP receptor blockade during percutaneous coronary intervention (PCI) is critical to prevent thrombotic events. In patients under chronic P2Y12 blockers, the use of additional loading dose (LD) before an elective PCI is debated. We aimed to investigate the rate of high on-treatment platelet reactivity ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.04.165
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Although combined supine and prone acquisitions improve the detection of inferolateral obstructive coronary artery disease (CAD), the predictors of inaccurate detection of inferolateral ischemia have not been reported by using cadmium zinc telluride (CZT) myocardial perfusion imaging (MPI). METHODS AND RESU...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2014.04.069
更新日期:2014-06-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2010.08.070
更新日期:2012-01-12 00:00:00
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journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ijcard.2003.03.007
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Several studies have shown contradictive findings regarding mortality and hospital admission time in patients presenting with ST-elevation myocardial infarction (STEMI). The aim of this study was to assess the impact of "on-" or "off-hour" admission on short- and long-term all-cause mortality of patients in ...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2017-10-01 00:00:00