Abstract:
BACKGROUND:While only few data exist correlating cardiovascular risk factors with volumetric measurements of coronary atheroma burden in patients with coronary artery disease, a recent report using intravascular ultrasound (IVUS) demonstrated independent predictors of atherosclerotic burden in a native coronary artery with relatively mild narrowing (20-50% diameter stenosis by visual estimation). The purpose of this study was to examine whether cardiovascular risk factors can predict atherosclerotic burden at severely narrowing segments (>50% diameter stenosis). METHODS:Patients who met the criteria (high-quality, automated pull-back IVUS images of severely narrowing segments prior to intervention) were identified from the IVUS database of the Cardiovascular Core Analysis Laboratory at Stanford University. Using commercially available planimetry software, lumen and vessel inside external elastic membrane areas were manually traced at every 0.5-mm interval in diseased segments. Using Simpson's method, vessel, lumen, and plaque (vessel minus lumen) volumes were calculated, and average area was calculated as volume data divided by length. Percent plaque volume was computed as plaque volume divided by vessel volume. Multiple linear regression analysis with backward selection was used to determine the risk factors for atherosclerotic burden. RESULTS:For percent plaque volume, diabetes or hypertension were predictors of more severe disease. For average plaque area, male gender or diabetes were predictors of more severe disease. These variables were also independent predictors in multivariate regression models. CONCLUSIONS:Male gender, hypertension, and diabetes are also strong independent predictors of atherosclerotic burden in coronary disease patients, though analyzed segments and disease severity were different.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Kaneda H,Kataoka T,Ako J,Honda Y,Yock PG,Fitzgerald PJdoi
10.1016/j.ijcard.2006.11.194subject
Has Abstractpub_date
2008-02-20 00:00:00pages
124-6issue
1eissn
0167-5273issn
1874-1754pii
S0167-5273(07)00218-5journal_volume
124pub_type
信件abstract::To assess whether infarct size, ischemic area and/or survival correlates with circulating atrial natriuretic peptides (long acting sodium stimulator, vessel dilator, or atrial natriuretic factor), these peptides were measured in a canine model of acute myocardial infarction. Elevations in the circulating concentration...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(94)02192-l
更新日期:1995-01-06 00:00:00
abstract::Persistent atrial standstill, characterized by absence of atrial activity on surface and intracavitary electrograms, absence of atrial mechanical activity, and inability to stimulate the atria electrically, is a rare disorder. Left atrial appendage blood flow has been reported to be related to P wave during sinus rhyt...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(96)02794-5
更新日期:1996-11-15 00:00:00
abstract::Atrial septal defect (ASD) accounts for approximately a third of all congenital heart disease in adults. It is rarely diagnosed and less likely to cause any symptoms during infancy, but approximately more than half become symptomatic around their fifth decade. In clinical setting it commonly presents as exertional dys...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2008.12.039
更新日期:2010-08-20 00:00:00
abstract:BACKGROUND:Gender differences have been reported in patients with acute VTE treated with antithrombotic drugs. OBJECTIVE:To address the relationship between gender and new oral anticoagulants (NOACs), we performed a meta-analysis to evaluate the incidence of recurrent VTE and major plus clinically relevant non-major b...
journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ijcard.2016.03.086
更新日期:2016-06-01 00:00:00
abstract::We examined 16 patients, aged 24 to 73, with ICD. Condition of qualification to the examined group was experiencing many discharges (from 25 to above 200) or electric shock (3 or more discharges following one after another). Most of the patients (14) were afraid of ICD discharges. 11 patients presented psychopathologi...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.08.027
更新日期:2009-02-20 00:00:00
abstract:BACKGROUND:Native T1 mapping has emerged as a noninvasive non-contrast magnetic resonance imaging (MRI) method to assess for diffuse myocardial fibrosis. However, LV native T1 time in AF patients and its clinical relevance are unclear. METHODS:Fifty paroxysmal AF patients referred for PVI (60 ± 8 years, 37 male) and 1...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.11.073
更新日期:2016-01-15 00:00:00
abstract::Acute ingestion of more than 200 mg dipyridamole may result in minor symptoms. The reported highest dosage of acute ingestion was 1250 mg. Most experiences of acute ingestion come from dipyridamole thallium image, oral application of 300-400 mg or intravenous 0.56 mg/kg. The systemic or cardiovascular complication cou...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(94)90120-1
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:A high slope of the ventilation vs. carbon dioxide relationship (VE/VCO₂ slope) during incremental exercise has been reported in several congenital heart disease (CHD) types, but it is not clear whether the main cause of high VE/VCO₂ slope is excessive ventilation or reduced perfusion. METHODS:We studied 16...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.04.285
更新日期:2015-07-15 00:00:00
abstract:BACKGROUND AND AIM:The problem of a possible gender bias in coronary heart disease management is still controversial. We studied gender differences in secondary preventive drug prescriptions and in referral to cardiac rehabilitation after acute coronary events in France. METHODS:An observational survey was carried out...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2003.04.003
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:We sought to investigate the association between LVEF and clinical outcomes after NSTEMI, and the benefit of guideline-recommended pharmacotherapy in elderly patients. BACKGROUND:New-onset reduction in LVEF is common after NSTEMI in patients of advanced age. There is little information about outcomes in rel...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2019.07.019
更新日期:2019-12-01 00:00:00
abstract:AIMS:To conduct a prospective, individual participant data (IPD) meta-analysis of randomised controlled trials comparing a polypill-based approach with usual care in high risk individuals. METHODS AND RESULTS:Three trials comparing polypill-based care with usual care in individuals with CVD or high calculated cardiova...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.12.015
更新日期:2016-02-15 00:00:00
abstract:BACKGROUND:Dietary pattern analysis is emerging as a practical, effective tool for relating comprehensive dietary intake to risk of cardiovascular disease mortality. However, no studies have applied this technique to a population outside of the developed world. METHODS:We conducted prospective cohort analyses in 11,11...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2012.04.041
更新日期:2013-08-20 00:00:00
abstract::This study was performed to evaluate the accuracy of exclusively non-invasive preoperative diagnostic work-up based on echocardiography and to assess the safety of cardiac surgery using this diagnostic approach in children with heart disease. During a 3. 5-year period, accuracy of preoperative (invasive and non-invasi...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/s0167-5273(00)00278-3
更新日期:2000-07-31 00:00:00
abstract::We investigated the acute effect of transdermal estradiol-17-beta on exercise-induced ischemia in 15 postmenopausal women (mean age 58 +/- 6 years) with syndrome X (angina pectoris, positive exercise test and normal coronary angiogram) and eight healthy women (mean age 58 +/- 5 years) in a placebo-controlled, double-b...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0167-5273(96)02560-0
更新日期:1996-04-19 00:00:00
abstract::A 15-year-old patient is presented with parasystolic ventricular tachycardia which was responsive to oral verapamil. We emphasize the value of verapamil in the treatment of this uncommon arrhythmia. ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(87)90300-7
更新日期:1987-04-01 00:00:00
abstract::Information concerning acute myocardial infarction after cannabis usage is limited and the actual mechanism of cannabis-induced myocardial infarction is not well known. In the report, we described a young man with an acute myocardial infarction and cannabis-induced coronary thrombosis. ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.08.012
更新日期:2007-09-03 00:00:00
abstract::In this study, the effect of celiprolol (beta-1-antagonist with beta-2-agonistic activity) on hemodynamic and electrocardiographic parameters of patients with congestive heart failure due to ischemic (iCMP) and non-ischemic (niCMP) origin should be evaluated. Sixteen patients were included into the study, nine with iC...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/s0167-5273(98)00377-5
更新日期:1999-03-15 00:00:00
abstract:BACKGROUND:After introduction of up-titration strategy, there are limited data on comparison between the effects of angiotensin converting enzyme inhibitors (ACEI) and angiotensin receptor blocker (ARB) in patients with heart failure with reduced ejection fraction (HFrEF). The study sought to investigate the associatio...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2017.12.002
更新日期:2018-04-15 00:00:00
abstract:INTRODUCTION:Sports activity has been associated with the development of atrial arrhythmias. Atrial fibrillation (AF) is frequently observed after successful ablation for atrial flutter. Sports activity as a risk factor for AF development after flutter ablation has not been studied. METHODS:We analyzed outcome in 137 ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.02.043
更新日期:2006-02-08 00:00:00
abstract::The negative inotropism, myocardial dilatation and cytotoxicity in inflammatory heart disorders may be due to increased generation of nitric oxide (NO) by immunological induction of a high output NO pathway. This short review discusses the initial experiments which lead to this hypothesis, and evaluates data that this...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/0167-5273(95)02386-b
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:Incidence and prognostic impact of heart failure (HF) progression has been not well addressed. METHODS:From 2009 until 2015, consecutive ambulatory HF patients were recruited. HF progression was defined by the presence of at least two of the following criteria: step up of ≥1 New York Heart Association (NYHA...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.08.049
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:Takotsubo cardiomyopathy (TTC) is a novel heart disease, mimicking acute myocardial infarction. The term "transient left ventricular dysfunction syndrome" (TLVDS) seems to be more appropriate since variant forms of TTC sparing apical segments (mid-ventricular ballooning syndrome (MVBS) and inverted TTC) have...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2009.04.025
更新日期:2010-10-08 00:00:00
abstract:PURPOSE:Our study aimed to assess pro-arrhythmogenic electrocardiographic changes during maximal physical exercise in patients operated for Tetralogy of Fallot (TOF). METHODS:TOF patients prospectively underwent: 1) bicycle ergometry, 2) cardiac MRI, and 3) 24-hour Holter. ECG data was analyzed at rest, at 60% of peak...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2007.02.009
更新日期:2008-03-14 00:00:00
abstract:INTRODUCTION:The progression of aortic stenosis (AS) has been shown to be faster in patients with the metabolic syndrome. We sought to determine the relationships between blood pressure, inflammation, oxidative stress and valvular inflammation in a population of normotensive and prehypertensive patients with AS. METHO...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2009.05.054
更新日期:2010-12-03 00:00:00
abstract::The data from 50 permanently paced children [mean standard deviation follow-up 5.3 +/- 3.7 years] were reviewed, with special attention being paid to the cause of complications and the efficacy of follow-up. The 5-year survival (SD) of the patients was 78 +/- 6%; mortality was mainly due to the underlying cardiac dise...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(91)90348-s
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND:Hypertension-induced cardiac dysfunction is variable among different anti-hypertensive medications. This study compares the effects of telmisartan and enalapril on echocardiographic parameters in hypertensive patients. MATERIALS AND METHODS:This was a randomised single blinded study. Eighty hypertensive pat...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2016.12.127
更新日期:2017-03-01 00:00:00
abstract::We report a patient with Takayasu arteritis (TA) who initially received stent placement (SP) following percutaneous transluminal balloon angioplasty for stenotic lesion of the left subclavian artery and subsequently had recurrent in-stent restenosis three times. Every time restenosis occurred, percutaneous translumina...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2003.04.019
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:The effects of adding moderate-to-high intensity inspiratory muscle training (IMT) to short-term aerobic and resistance exercise (combined training [CT]), after coronary artery bypass grafting (CABG) are not established. This study aimed to determine the effects of moderate-to-high intensity IMT + CT on exer...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2018.12.013
更新日期:2019-03-15 00:00:00
abstract::We describe a series of five patients who had cardiac tamponade at the time of initial presentation as a result of extracardiac malignancy. Three cases had adenocarcinoma and two had squamous cell carcinoma. The diagnosis of bronchogenic carcinoma was established after appropriate investigations in three cases. One pa...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(89)90063-6
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND:The presence of small areas of necrosis has been occasionally reported immediately following apical ballooning syndrome (ABS). However, their persistence at later stages and impact on long-term prognosis are currently unknown. METHODS:Twenty consecutive patients admitted for ABS between 2004 and 2007 were p...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ijcard.2008.08.023
更新日期:2010-02-18 00:00:00