当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF CARDIOLOGY期刊下所有文献 > Transient left ventricular dysfunction syndrome: patho-physiological bases through nuclear medicine imaging.

Transient left ventricular dysfunction syndrome: patho-physiological bases through nuclear medicine imaging.

Abstract：

BACKGROUND:Takotsubo cardiomyopathy (TTC) is a novel heart disease, mimicking acute myocardial infarction. The term "transient left ventricular dysfunction syndrome" (TLVDS) seems to be more appropriate since variant forms of TTC sparing apical segments (mid-ventricular ballooning syndrome (MVBS) and inverted TTC) have been described. Patho-physiological bases of TLVDS remain poorly understood and its optimal management is until now empirical. Our aim was to characterize patho-physiological mechanisms of TLVDS by means of nuclear medicine procedures and to discuss the clinical usefulness of isotopic imaging for a non-invasive diagnosis of TLVDS. METHODS AND RESULTS:During the sub acute phase, eighteen patients with TLVDS (13 TTC and 5 MVBS) underwent myocardial (99m)Tc-tetrofosmin or (201)Thallium Gated Single Photon Emission Computed Tomography (G-SPECT) (n=11), (123)I-mIBG SPECT (n=8) and (18)F-FDG Gated Positron Emission Tomography (G-PET) (n=15), assessing respectively LV perfusion, sympathetic innervation and glucose metabolism. Hypocontractile LV segments were characterized by normal perfusion but reduced uptake of (18)F-FDG and (123)I-mIBG. Topography and extent of metabolic defects and innervation abnormalities were largely overlapping. Follow-up (123)I-mIBG SPECT and (18)F-FDG G-PET were performed in selected patients showing rapid normalization of LV motion and progressive improvement of both glucose metabolism and sympathetic innervation. DISCUSSION:With the hypothesis of neurogenic stunned myocardium as the central causative mechanism of TLVDS, (123)I-mIBG SPECT seems to be the most specific diagnostic technique. Sympathetic function and glucose metabolism seem to be strictly correlated in the hypocontractile LV segments. Finally, our results underline the role of nuclear imaging in the setting of patho-physiological mechanisms of TLVDS.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Cimarelli S,Sauer F,Morel O,Ohlmann P,Constantinesco A,Imperiale A

doi

10.1016/j.ijcard.2009.04.025

subject

Has Abstract

pub_date

2010-10-08 00:00:00

pages

212-8

issue

2

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(09)00486-0

journal_volume

144

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF CARDIOLOGY文献大全
  • Sarpogrelate protects against high glucose-induced endothelial dysfunction and oxidative stress.

    abstract：:This study was designed to investigate the effect of sarpogrelate hydrochloride on impaired endothelium-dependent relaxation (EDR) induced by high glucose in isolated rat aorta. Both acetylcholine-induced EDR and sodium nitroprusside-induced endothelium-independent relaxation (EIR) were measured after the rings were e...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2009.09.539

    authors： Sun YM,Su Y,Jin HB,Li J,Bi S

    更新日期：2011-03-17 00:00:00

  • The size of infarction as judged enzymatically in 1974 patients with acute myocardial infarction. Relation with symptomatology, infarct localization and type of infarction.

    abstract：:A common data base of six coronary care units containing personal and clinical data of 17462 patients was used to investigate the relation between clinical symptoms of patients with acute myocardial infarction and size of infarction. In 1974 of the 5110 patients, in whom a final diagnosis of infarction was made, size ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(88)90080-0

    authors： van der Laarse A,van Leeuwen FT,Krul R,Tuinstra CL,Lie KI

    更新日期：1988-05-01 00:00:00

  • Intracoronary autologous bone marrow cell transplantation beneficially modulates heart rate variability.

    abstract：:The effect of intracoronary administration of autologous bone marrow cells on autonomic modulation of heart rate has not yet been demonstrated. Therefore, we investigated different parameters of heart rate variability (HRV) in 46 patients without (n=23) or with (n=23) intracoronary stem cell therapy after transmural m...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2006.07.169

    authors： Schueller PO,Meyer C,Brehm M,Wernet P,Schannwell CM,Strauer BE

    更新日期：2007-07-31 00:00:00

  • Usefulness of basal B-type natriuretic peptide levels for the diagnosis of diastolic heart failure in young patients: an echocardiographic-catheterization study.

    abstract：:The aim of the present study was to address the diagnostic relevance of B-type natriuretic peptide (BNP) for the diagnosis of diastolic heart failure (DHF) in young patients presenting with chronic, isolated dyspnea. We prospectively included 26 consecutive patients with a left ventricular ejection fraction >50% refer...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2009.03.127

    authors： Arques S,Jaubert MP,Bonello L,Roux E,Armero S,Sbragia P,Nicoud A,Paganelli F

    更新日期：2010-11-05 00:00:00

  • Doxazosin GITS versus standard doxazosin in mild to moderate hypertension.

    abstract：BACKGROUND:The selective alpha 1-adrenoceptor antagonist doxazosin in both standard formulation and gastrointestinal therapeutic system (GITS) controlled-release formulation is effective for hypertension without having a negative impact on serum lipids. This study was designed to compare the relative efficacy of these ...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ijcard.2004.07.005

    authors： Calvo C,Gil-Extremera B,Gomez-Fernández P,Masramon X,Pueyo C,Armada B

    更新日期：2005-05-11 00:00:00

  • Prominent basal and middle strain longitudinal involvement in newly-diagnosed and never treated hypertensive patients without clear-cut hypertrophy.

    abstract：BACKGROUND:Left ventricular (LV) global longitudinal strain (GLS) can detect an early dysfunction in arterial hypertension. We investigated regional LV patterns of longitudinal strain (LS) and base-to-apex behaviour in newly diagnosed, never-treated hypertensive patients (HTN) without LV hypertrophy. METHODS:180 HTN a...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.01.038

    authors： Lembo M,Santoro C,Sorrentino R,Fazio V,Canonico ME,Chiariello L,Galderisi M,Esposito R

    更新日期：2020-04-01 00:00:00

  • Tandospirone reduces wasting and improves cardiac function in experimental cancer cachexia.

    abstract：BACKGROUND:Cancer cachexia is thought to be the cause of >20% of cancer related deaths. Symptoms of cancer cachexia patients include depression and anorexia significantly worsening their quality of life. Moreover, in rodent models of cancer cachexia atrophy of the heart has been shown to impair cardiac function. Here, ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2013.10.022

    authors： Elkina Y,Palus S,Tschirner A,Hartmann K,von Haehling S,Doehner W,Mayer U,Coats AJ,Beadle J,Anker SD,Springer J

    更新日期：2013-12-10 00:00:00

  • Chest pain centers: moving toward proactive acute coronary care.

    abstract：:Ischemic heart disease is the major cause of death, disability and lost productivity in the developed countries of the world. The evolution of cardiac care units has improved patient survival from myocardial infarctions, but requires a high-tech, very expensive treatment facility. Chest pain centers, located in emerge...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/s0167-5273(99)00160-6

    authors： Bahr RD

    更新日期：2000-01-15 00:00:00

  • A focused update on emerging prognostic determinants in distal left main percutaneous coronary intervention.

    abstract：:A distal location of the atherosclerotic plaque is one of the most powerful predictors of adverse events after left main angioplasty. However, bifurcations are not alike and may differ with regards to a number of variables, including the angle of the bifurcation, the presence of a ramus, the burden of downstream coron...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijcard.2011.08.059

    authors： Capodanno D,Calvi V,Tamburino C

    更新日期：2012-09-20 00:00:00

  • Impact of chronic obstructive pulmonary disease on clinical course after an episode of acute heart failure. EAHFE-COPD study.

    abstract：OBJECTIVE:To study if the coexistence of chronic obstructive pulmonary disease (COPD) in patients diagnosed with acute heart failure (AHF) at the emergency department (ED) has an impact on short- and long-term outcomes. METHOD:The EAHFE-COPD study included patients who attended in 34 Spanish EDs for AHF. We compared p...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.11.013

    authors： Jacob J,Tost J,Miró Ò,Herrero P,Martín-Sánchez FJ,Llorens P,ICA-SEMES Research Group.

    更新日期：2017-01-15 00:00:00

  • Prevalence of M4 macrophages within human coronary atherosclerotic plaques is associated with features of plaque instability.

    abstract：BACKGROUND:The platelet chemokine CXCL4 induces monocyte differentiation resulting in a macrophage phenotype called "M4", which co-expresses CD68, MMP7, and S100A8. We hypothesized that M4 macrophages are associated with plaque destabilization. METHODS:Atherosclerotic arteries were obtained from explanted hearts of pa...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2015.03.151

    authors： Erbel C,Wolf A,Lasitschka F,Linden F,Domschke G,Akhavanpoor M,Doesch AO,Katus HA,Gleissner CA

    更新日期：2015-01-01 00:00:00

  • Benefits of final proximal optimization technique (POT) in provisional stenting.

    abstract：AIMS:Initial proximal optimization technique (POT) in provisional stenting improves global malapposition, side-branch (SB) obstruction (SBO) and conservation of arterial circularity. The specific mechanical effects of a final POT sequence concluding the main provisional stenting techniques, on the other hand, are unkno...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2018.09.041

    authors： Dérimay F,Rioufol G,Cellier G,Souteyrand G,Finet G

    更新日期：2019-01-01 00:00:00

  • Plasma chemotactic activity during dipyridamole induced myocardial ischemia.

    abstract：BACKGROUND:We have previously reported that transient myocardial ischemia induced during exercise or dipyridamole challenge leads to the release of increased amounts of hydrogen peroxide into circulating blood. It would indicate that the temporary functional changes within myocardial cells may constitute there a steril...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/s0167-5273(97)00267-2

    authors： Wysocki H,Kazmierczak M,Wykretowicz A,Szczepanik A,Minczykowski A

    更新日期：1998-01-05 00:00:00

  • Performing diagnostic coronary angiography to evaluate high-risk cardiac donors: A French nationwide cohort study.

    abstract：BACKGROUND:Allograft shortage might be overcome by the use of hearts from expanded-criteria donors (ECD) but their estimated high-risk of coronary artery disease (CAD) results in a limited utilization of these hearts for transplantation. We aimed to determine if performing coronary angiography (CA) in ECD enhances card...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2018.08.003

    authors： Ivanes F,Cantrelle C,Genet T,Le Feuvre C,Legeai C,Jasseron C,Pipien I,Epailly E,Bastien O,Angoulvant D,Dorent R

    更新日期：2019-02-15 00:00:00

  • Cross-talk between mineralocorticoid receptor/angiotensin II type 1 receptor and mitogen-activated protein kinase pathways underlies aldosterone-induced atrial fibrotic responses in HL-1 cardiomyocytes.

    abstract：BACKGROUND:Aldosterone is increasingly recognized for its involvement in atrial structural remodeling. However, the precise molecular mechanisms and signal pathways underlying aldosterone-induced atrial fibrosis are unknown. METHODS:Western blotting was used to investigate the effects of aldosterone on the expression ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2013.06.046

    authors： Tsai CF,Yang SF,Chu HJ,Ueng KC

    更新日期：2013-10-25 00:00:00

  • The analysis of left atrial function predicts the severity of functional impairment in chronic heart failure: The FLASH multicenter study.

    abstract：BACKGROUND:Heart failure (HF) patients present with a variety of symptoms at different stages of the disease, but the underlying pathophysiology still is unclear. Left atrial (LA) function might be tightly related to changes in patients' symptoms, more than morphological and anatomic heart features, measurable by ultra...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ijcard.2019.03.063

    authors： Cameli M,Sciaccaluga C,Loiacono F,Simova I,Miglioranza MH,Nistor D,Bandera F,Emdin M,Giannoni A,Ciccone MM,Devito F,Guaricci AI,Favale S,Lisi M,Mandoli GE,Henein M,Mondillo S

    更新日期：2019-07-01 00:00:00

  • Association between VO₂ peak estimated by a 1-km treadmill walk and mortality. A 10-year follow-up study in patients with cardiovascular disease.

    abstract：PURPOSE:The aim of this study is to assess the association between peak oxygen uptake (VO2 peak), determined using a perceptually regulated 1-km walking test (1k-TWT), and all-cause mortality in cardiac patients. METHODS:1255 male patients, aged 25-85 years, completed a moderate 1k-TWT to estimate VO2 peak. Subjects w...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2014.02.039

    authors： Grazzi G,Myers J,Bernardi E,Terranova F,Grossi G,Codecà L,Volpato S,Conconi F,Mazzoni G,Chiaranda G

    更新日期：2014-05-01 00:00:00

  • Reproducibility of the head-up tilt test results in children with vasovagal syncope.

    abstract：BACKGROUND:This prospective study aims to investigate the reproducibility of HUTT results in children with typical history of vasovagal syncope. METHODS:Between October 1996 and October 1999, 58 children with a history of typical vasovagal syncope attacks were evaluated with head up tilt test (HUTT). The table was til...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/s0167-5273(02)00379-0

    authors： Alehan D,Uner A,Ayabakan C,Ozer S,Ozme S

    更新日期：2003-03-01 00:00:00

  • A new risk model of assessing left atrial appendage thrombus in patients with atrial fibrillation - Using multiple clinical and transesophageal echocardiography parameters.

    abstract：BACKGROUNDS:Predicting left atrial appendage thrombus (LAAT) in non-valvular atrial fibrillation (NVAF) patients need more precisely quantified risk models. In this study, we attempted to review the risk markers for LAAT and develop a simple and reliable model for LAAT prediction. METHODS:The study included 307 patien...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.04.039

    authors： Chen L,Zinda A,Rossi N,Han XJ,Sprankle S,Bullock-Palmer R,Zingrone D,Moshiyakov M,Szawlewicz J,Mogtader A,Hsi DH

    更新日期：2020-09-01 00:00:00

  • Clinical utility of circulating interleukin-6 concentrations in the detection of functionally relevant coronary artery disease.

    abstract：BACKGROUND:Inflammation plays a major role in the pathogenesis of coronary artery disease (CAD). METHODS:We hypothesized, that quantifying inflammation by measuring circulating interleukin-6 concentrations help in the diagnosis and/or prediction of functionally relevant CAD. Among consecutive patients with symptoms su...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2018.10.029

    authors： Walter J,Tanglay Y,du Fay de Lavallaz J,Strebel I,Boeddinghaus J,Twerenbold R,Doerflinger S,Puelacher C,Nestelberger T,Wussler D,Amrein M,Badertscher P,Todd J,Rentsch K,Fahrni G,Jeger R,Kaiser C,Reichlin T,Mueller C

    更新日期：2019-01-15 00:00:00

  • Impact of left atrial volume in prediction of outcome after cardiac resynchronization therapy.

    abstract：UNLABELLED:Left atrial volume index (LAVI) as a predictor of mortality has not been well investigated in patients with cardiac resynchronization therapy (CRT). The purpose of this study is to evaluate the impact of LAVI in predicting mortality in CRT patients. METHODS:We studied 100 consecutive patients who received C...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2010.06.016

    authors： Shen X,Nair CK,Holmberg MJ,Mooss AN,Koruth J,Wang F,Maciejewski S,Esterbrooks DJ

    更新日期：2011-10-06 00:00:00

  • Quality of life and the associated risk of all-cause mortality in nonischemic heart failure.

    abstract：OBJECTIVES:To examine the association between health-related quality of life (HRQoL) and mortality in patients with heart failure (HF). BACKGROUND:The potential association of HRQoL and mortality in patients with HF is unclear. We investigated this association in The Danish Study to Assess the Efficacy of Implantable ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.02.008

    authors： Bundgaard JS,Thune JJ,Gislason G,Fosbøl EL,Torp-Pedersen C,Aagaard D,Nielsen JC,Haarbo J,Thøgersen AM,Videbæk L,Jensen G,Olesen LL,Kristensen SL,Pedersen SS,Køber L,Mogensen UM

    更新日期：2020-04-15 00:00:00

  • Ablation of SIRT3 causes coronary microvascular dysfunction and impairs cardiac recovery post myocardial ischemia.

    abstract：RATIONALE:Sirtuin (SIRT3), a major nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase in mitochondria, declines with aging and its ablation is associated with accelerated development of cardiovascular diseases. However, the role of SIRT3 in coronary microvascular function and post-MI recovery has not been...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.04.092

    authors： He X,Zeng H,Chen JX

    更新日期：2016-07-15 00:00:00

  • Prognostic significance of left anterior fascicular block and its relation with coronary artery disease in old patients based on 570 autopsy cases.

    abstract：BACKGROUND:Left Anterior Fascicular Block (LAFB) occurs frequently among the elderly, and have a correlation with coronary artery disease (CAD), yet controversies regarding its clinical significance still remain. METHODS:We carried on a retrospective study involving 92 LAFB and 478 non-LAFB patients, in which anatomic...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2018.06.069

    authors： Ding S,Chai K,Li Y,Fang F,Yang J,Wang H

    更新日期：2018-10-15 00:00:00

  • Invasive treatment performed for acute myocardial infarction in a patient with immune thrombocytopenic purpura.

    abstract：:Acute myocardial infarction (AMI) is infrequent in patients with idiopathic thrombocytopenic purpura (ITP) so the best treatment is not well known. The next case shows a 37-year-old man with chronic ITP who suffered an anterior AMI, the platelet count at admission was 39,000 microL. He was treated successfully with pr...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2007.05.075

    authors： Gracia MC,Cebollero IC,Lezcano JS,Osuna GG,Miguel JA,Peralta LP

    更新日期：2008-07-21 00:00:00

  • Efficacy of alirocumab in high cardiovascular risk populations with or without heterozygous familial hypercholesterolemia: Pooled analysis of eight ODYSSEY Phase 3 clinical program trials.

    abstract：OBJECTIVES:Despite maximally tolerated statin therapy, many patients with high cardiovascular risk, with or without heterozygous familial hypercholesterolemia may require additional low-density lipoprotein cholesterol (LDL-C) reduction. We report pooled alirocumab (ALI) efficacy and safety data from eight Phase 3 trial...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ijcard.2016.08.273

    authors： Farnier M,Gaudet D,Valcheva V,Minini P,Miller K,Cariou B

    更新日期：2016-11-15 00:00:00

  • Treatment of failed aortic bioprostheses: An evaluation of conventional redo surgery and transfemoral transcatheter aortic valve-in-valve implantation.

    abstract：BACKGROUND:The use of bioprostheses for surgical aortic valve replacement increased substantially within the last years. In case of prosthesis failure, re-SAVR is standard of care, whereas valve-in-valve deployment of a transfemoral transcatheter aortic valve prosthesis (VinV-TFAVI) has recently emerged as an alternati...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2019.09.039

    authors： Woitek FJ,Stachel G,Kiefer P,Haussig S,Leontyev S,Schlotter F,Mende M,Hommel J,Crusius L,Spindler A,Mohr FW,Schuler G,Thiele H,Borger MA,Linke A,Holzhey D,Mangner N

    更新日期：2020-02-01 00:00:00

  • Prevalence of Takayasu arteritis in young women with acute ischemic heart disease.

    abstract：OBJECTIVES:Takayasu arteritis (TA), a systemic vasculitis typically occurring in female patients aged ≤40, can affect coronary arteries and cause ischemic heart disease (IHD). In this study, we investigated the prevalence of TA in young women presenting with IHD in the Emergency Department. METHODS:We evaluated hospit...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2017.10.067

    authors： Cavalli G,Tomelleri A,Di Napoli D,Baldissera E,Dagna L

    更新日期：2018-02-01 00:00:00

  • :Influence of the duration of Holter monitoring on the detection of arrhythmia recurrences after catheter ablation of atrial fibrillation: implications for patient follow-up.

    abstract：:We investigated the influence of Holter duration on the detection of recurrences after ablation for atrial fibrillation (AF). Two-hundred-and-fifteen patients underwent a 7-day Holter ECG at 6 months after catheter ablation. We analyzed the number of patients who had a recurrence within the first 24, 48, 72 h etc. up ...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2008.10.004

    authors： Dagres N,Kottkamp H,Piorkowski C,Weis S,Arya A,Sommer P,Bode K,Gerds-Li JH,Kremastinos DT,Hindricks G

    更新日期：2010-03-18 00:00:00

  • Therapeutic options of Angiotensin Receptor Neprilysin inhibitors (ARNis) in chronic heart failure with reduced ejection fraction: Beyond RAAS and sympathetic nervous system inhibition.

    abstract：:In heart failure, in addition to the renin-angiotensin-aldosterone system and sympathetic nervous system, the natriuretic peptide (NP) system plays a fundamental role among compensating mechanisms. The NPs undergo rapid enzymatic degradation that limits their vasorelaxant, natriuretic, and diuretic actions. Degradatio...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijcard.2016.04.180

    authors： Volterrani M,Iellamo F,Senni M,Piepoli MF

    更新日期：2017-01-01 00:00:00