Performance characteristics of a model secreting acinus.

Abstract:

:An acinus is the principal secretion unit of an exocrine gland. This paper sets up a mathematical model of an acinus and examines the effect on the output of varying the operating parameters, both of the secretion mechanism and the fluid properties. Particular reference is made to acini of the pancreas. The question of whether the effects of cystic fibrosis on the pancreas can be attributed to the increased viscosity of the exudate is also considered. The work identifies key parameters, and their quantitative ranges, which would need to be examined experimentally in order to resolve this question.

journal_name

Biorheology

journal_title

Biorheology

authors

Grigg CH,Fitz-Gerald JM

doi

10.3233/bir-1986-23103

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

25-50

issue

1

eissn

0006-355X

issn

1878-5034

journal_volume

23

pub_type

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