Abstract：
:In 84 cases of keratoplasty, all patients had densely vascularized corneas and a history of prior exposure to HLA antigens by pregnancy, blood transfusion, or previous transplantation. Donors were selected on the basis of a negative crossmatch to avoid donor antigens to which the recipient was preimmunized. The overall rate of graft failure from rejection was 15%. A retrospective analysis of donor-recipient HLA matching in 103 high-risk cases showed no consistent correlation between the number of antigens shared and graft outcome. These findings indicated negative cross-match to be important in donor selection for keratoplasty in high-risk cases.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Stark WJ,Taylor HR,Bias WB,Maumenee AEdoi
10.1016/0002-9394(78)90174-5subject
Has Abstractpub_date
1978-11-01 00:00:00pages
595-604issue
5eissn
0002-9394issn
1879-1891pii
0002-9394(78)90174-5journal_volume
86pub_type
杂志文章abstract：PURPOSE:To describe the natural history of Leber congenital amaurosis (LCA) associated with GUCY2D variants (GUCY2D-LCA) in a cohort of children and adults, in preparation for trials of novel therapies. DESIGN:Retrospective case series. METHODS:Participants: Patients with GUCY2D-LCA at a single referral center. PROC...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2019.10.019
更新日期：2020-02-01 00:00:00
abstract：:Cataract operations may be recommended when retinal disease is suspected but cannot be adequately diagnosed or treated because of lens opacity. We evaluated the outcome of cataract operations performed under those circumstances. We reviewed the records of 119 patients who were examined at the Wilmer Retinal Vascular C...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75793-9
更新日期：1994-10-15 00:00:00
abstract：:We successfully treated six patients with culture-proven acute bacterial endophthalmitis by a combination of emergency pars plana vitrectomy and the instillation of intravitreal antibiotics. All six patients regained satisfactory vision. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76806-0
更新日期：1978-08-01 00:00:00
abstract：PURPOSE:To evaluate the effect of contact lens (CL) wear and visual display terminal (VDT) work on the ocular surface and tear functions. DESIGN:Prospective case-control study. METHODS:Sixty-nine CL wearers (45 women and 24 men; mean age, 35.2 ± 7.3 years), and 102 age- and sex-matched non-CL wearers were enrolled in...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.05.025
更新日期：2011-12-01 00:00:00
abstract：PURPOSE:To explore the possible involvement of adrenomedullin in the pathophysiology of intraocular and orbital tumors. METHODS:Competitive reverse transcription-polymerase chain reaction was used to determine adrenomedullin mRNA levels in the tissues from 40 consecutive patients (40 eyes) undergoing vitrectomy, orbit...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00442-0
更新日期：2000-04-01 00:00:00
abstract：PURPOSE:To compare the long-term efficacy and safety of 2 operation methods for late in-the-bag intraocular lens (IOL) dislocation. DESIGN:Prospective, randomized, parallel group surgical clinical trial. METHODS:During a 3-year period, 104 patients (104 eyes) were assigned one group for IOL repositioning by scleral s...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2019.05.030
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:To evaluate the diagnostic performance characteristics of the Van Herick assessment (VHA) for identifying angle closure compared to gold-standard gonioscopy, as conducted by trained observers of varying expertise. DESIGN:Reliability analysis. METHODS:Patients (n = 131) from a glaucoma referral clinic aged ≥50...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.07.026
更新日期：2018-11-01 00:00:00
abstract：:A 35-year-old woman with Engelmann's disease and systemic lupus erythematosus developed spontaneous luxation of the globe and glaucoma. Radiological studies demonstrated increased sclerosis of the orbital bones and decreased orbital volumes, the probable cause of the luxation and the glaucoma. The glaucoma was control...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(77)90917-5
更新日期：1977-06-01 00:00:00
abstract：:We treated two patients with Crohn's disease and one patient with ulcerative colitis who developed headache, papilledema, and intracranial hypertension (pseudotumor cerebri) during corticosteroid withdrawal. One had four separate episodes with corticosteroid withdrawal, which suggested a causal relationship. This asso...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73145-9
更新日期：1994-03-15 00:00:00
abstract：:I have modified a Maumenee-Park eyelid speculum to permit eyelid retraction in the direct plane of action of the lids and to avoid pressure on the globe from the speculum weight. A ball-joint at the end of the blade allows the blade to adjust with the eyelid. Increased angulation of the sidearm places the blade perpen...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(82)90711-5
更新日期：1982-01-01 00:00:00
abstract：PURPOSE:To report a case of primary systemic nonfamilial amyloidosis studied by fluorescein angiography and indocyanine green angiography. METHODS:Case report. A 59-year-old woman with primary systemic nonfamilial amyloidosis presented bilateral diffuse deep hemorrhages and pigmentary mottling at the posterior pole. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00506-7
更新日期：2000-08-01 00:00:00
abstract：:We used a technique for surgical management of fibrovascular membranes to relieve epiretinal tangential traction when present in proliferative diabetic retinopathy. Sharp dissection with intraocular scissors was used to segment fibrovascular and cortical vitreous membranes together with cauterization of large vessels ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(80)90012-4
更新日期：1980-03-01 00:00:00
abstract：PURPOSE:To assess the efficacy and safety of adjunctive daunorubicin during vitrectomy surgery in eyes with idiopathic proliferative vitreoretinopathy (PVR). METHODS:Two hundred eighty-six eyes (286 patients) with stage C2 (Retina Society Classification, 1983) or more advanced preoperative PVR in which surgery with si...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0002-9394(98)00115-9
更新日期：1998-10-01 00:00:00
abstract：:A 59-year-old woman with no evidence of glaucoma developed secondary open-angle glaucoma after an intracapsular cataract extraction complicated by vitreous and iris incarceration. Histopathologic and scanning and electron microscopic studies of the enucleated eye 22 years later revealed extensive proliferation of iris...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90520-8
更新日期：1979-09-01 00:00:00
abstract：PURPOSE:To critically assess the evidence base regarding outcomes following cataract surgery in uveitic cases. DESIGN:Systematic evidence-based review and meta-analysis. METHODS:A comprehensive search query was performed on MEDLINE, EMBASE, CINHAL, and CENTRAL databases. Relevant publications were identified by revie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.ajo.2014.06.018
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:To prospectively compare the degree of posterior capsule opacification (PCO) after AquaLase and NeoSoniX phacoemulsification methods during the 3-year follow-up period. DESIGN:Prospective, randomized clinical trial. METHODS:Setting at the Department of Ophthalmology, University Hospital in Hradec Králové. Pat...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2009.03.027
更新日期：2009-09-01 00:00:00
abstract：:A 29-year-old woman had a pigmented ciliary body mass that extended through the iris into the anterior chamber. On the basis of clinical findings and ancillary diagnostic studies, the clinical diagnosis was malignant melanoma of the ciliary body. The enucleated eye showed the tumor to be composed of cells identical to...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(80)90278-0
更新日期：1980-05-01 00:00:00
abstract：PURPOSE:To identify associations between severity of sickle cell retinopathy (SCR) and other clinical, laboratory, or treatment factors relevant to sickle cell disease (SCD). DESIGN:Retrospective cohort study. METHODS:We investigated clinical, laboratory, and demographic associations with the severity of SCR in 296 p...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.09.025
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:To investigate the potential influences that affect visual acuity (VA) outcome in a clinic-based cohort of age-related macular degeneration (AMD) patients undergoing anti-vascular endothelial growth factor (anti-VEGF) treatment for choroidal neovascularization. DESIGN:Prospective interventional case series. M...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.09.013
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:The prediction of atherosclerosis using retinal fundus images and deep learning has not been shown possible. The purpose of this study was to develop a deep learning model which predicted atherosclerosis by using retinal fundus images and to verify its clinical implications by conducting a retrospective cohort ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.03.027
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To study the glistening formation in various hydrophobic-acrylic intraocular lens (IOL) models, and to evaluate the effect of glistenings on light scattering in these IOLs. DESIGN:Laboratory investigation. METHODS:The susceptibility of the hydrophobic-acrylic material to develop glistenings was evaluated in 6...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.08.032
更新日期：2018-12-01 00:00:00
abstract：PURPOSE:To evaluate the possible toxicity of indocyanine green (ICG) dye in macular hole surgery by comparing functional results after successful surgeries performed with and without staining. DESIGN:Prospective observational case series. METHODS:In a study conducted at our department, 30 eyes of 29 patients with idi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.05.054
更新日期：2006-11-01 00:00:00
abstract：PURPOSE:To detect the prognostic factors associated with initial reattachment after primary pars plana vitrectomy (PPV) with gas tamponade for retinal detachment attributable to macular hole (MHRD). DESIGN:Retrospective, multicenter, interventional case series. METHODS:This study included 49 eyes of 48 patients with ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2008.04.022
更新日期：2008-08-01 00:00:00
abstract：:Three patients developed anisocoria as a result of third nerve palsies caused by intracranial lesions: two in the cavernous sinus and one in the mesencephalon. Pharmacologic testing using low concentration pilocarpine showed apparent preganglionic parasympathetic supersensitivity of the abnormal pupil. These findings ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(87)90231-5
更新日期：1987-10-15 00:00:00
abstract：:In a postmortem study of 57 diabetic patients, 19 of 23 patients with blood glucose levels greater than 200 mg/100 ml in the 72-hour period before death showed the characteristic histologic findings of "lacy" vacuolation of the iris pigment epithelium as well as vacuolation of the renal tubules (Armanni-Ebstein nephro...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90749-7
更新日期：1975-05-01 00:00:00
abstract：PURPOSE:To report the efficacy of an aggressive systematic regimen for the treatment of acute nonarteritic central retinal artery occlusion (CRAO). METHODS:Eleven patients who had unilateral CRAO with symptoms of fewer than 48 hours' duration were treated with an aggressive stepwise systematic regimen until retinal ci...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00359-1
更新日期：1999-12-01 00:00:00
abstract：:We conducted a prospective randomized clinical trial on the use of 2% hydroxypropyl methylcellulose and 1% sodium hyaluronate in the anterior chamber during anterior capsulotomy and nuclear expression in extracapsular cataract extraction with posterior chamber lens implantation in 70 patients. Both viscoelastic substa...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0002-9394(86)90399-5
更新日期：1986-12-15 00:00:00
abstract：:We analyzed 34 sets of optic disk photographs from 19 patients with glaucoma who had been followed up for ten years to evaluate changes in the position of the vasculature of the optic disks over time. Each photograph was analyzed by an image analyzer's edge-defining program for optic disk analysis and by three experie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74101-7
更新日期：1987-11-15 00:00:00
abstract：PURPOSE:To determine the haptic position in transsclerally sutured posterior chamber lenses. METHODS:Fifty eyes with transsclerally sutured posterior chamber lenses were evaluated gonioscopically to determine the superior haptic position using previous peripheral iridectomies. RESULTS:The superior haptic of the trans...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70146-1
更新日期：1997-03-01 00:00:00
abstract：PURPOSE:To examine the development and management of glaucoma in patients with ocular chemical burns. DESIGN:Retrospective, observational case series. METHODS:setting: University of Washington Eye Clinics. patient population: Twenty-nine eyes (18 patients) with ocular chemical burns seen between 1997 and 2010 with a ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.03.026
更新日期：2012-09-01 00:00:00
