Localized pili canaliculi and trianguli.

abstract：:Diabetic dermopathy (DD) is the most common cutaneous manifestation of diabetes mellitus. DD refers to atrophic, hyperpigmented macules characteristically located on the shins of patients with diabetes. They have an unfavorable association with the 3 most common microangiopathic complications of diabetes mellitus: neu...

journal_title：Journal of the American Academy of Dermatology

authors： Morgan AJ,Schwartz RA

更新日期：2008-03-01 00:00:00

abstract：:Sixteen patients with granular cell tumors were seen between 1964 and 1979. The medical data of these patients showed an average age incidence of 39 years and a greater frequency among Negroes (69%) and in female patients (62.5%). The most common sign (in 12 of 16 patients) was the presence of an asymptomatic mass. Th...

journal_title：Journal of the American Academy of Dermatology

authors： Apisarnthanarax P

更新日期：1981-08-01 00:00:00

abstract：:Incontinentia pigmenti is a rare genodermatosis of unknown etiology. A female infant with features typical of this disease was found to have basophils in early vesicular lesions. Mediators from these cells may be responsible for the accumulation of eosinophils in these lesions. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schmalstieg FC,Jorizzo JL,Tschen J,Subrt P

更新日期：1984-02-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs have been shown to inhibit inflammation, an integral part of the wound-healing process. Compromised wound repair has been demonstrated in laboratory animals administered high-dose nonsteroidal anti-inflammatory drugs, a phenomenon we speculate could occur in humans undergoing surge...

journal_title：Journal of the American Academy of Dermatology

authors： Proper SA,Fenske NA,Burnett SM,Luria LW

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:The evidence of hairs grouped into well-defined follicular units has given a new vision of hair anatomy and pathology. The sebaceous glands and the arrector pili muscle, as part of the pilosebaceous unit, should be viewed as important parts of this organized follicular unit structure. OBJECTIVE:This study w...

journal_title：Journal of the American Academy of Dermatology

authors： Poblet E,Jiménez F,Ortega F

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Laser resurfacing has been used for treatment of photoaged facial skin since late 1993. Very few long-term follow-up studies regarding the effectiveness and side effects of this procedure have been reported. METHOD:Patients who received carbon dioxide laser resurfacing for facial photoaging and wrinkling fr...

journal_title：Journal of the American Academy of Dermatology

authors： Manuskiatti W,Fitzpatrick RE,Goldman MP

更新日期：1999-03-01 00:00:00

abstract：:We used an avidin-biotin complex immunoperoxidase technique with various monoclonal antibodies to determine Langerhans cell densities, class II antigen expression on keratinocytes, and phenotypes of other infiltrating cells in several malignant and benign epithelial tumors of the skin. Our observations indicate (1) th...

journal_title：Journal of the American Academy of Dermatology

authors： Chen HD,Zhao YM,Sun G,Yang CY

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma, typically presents in middle-aged to elderly individuals. OBJECTIVE:We sought to study the demographics, clinicopathologic features, treatment response, and prognosis of patients with biopsy-proven MF diagnosed before 20 years of age...

journal_title：Journal of the American Academy of Dermatology

authors： Boulos S,Vaid R,Aladily TN,Ivan DS,Talpur R,Duvic M

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:ESPRIT is an ongoing, 10-year, observational registry, evaluating long-term safety and effectiveness of adalimumab treatment in routine clinical practice for patients with moderate to severe, chronic plaque psoriasis. OBJECTIVES:Initial 5-year results are reported. METHODS:Two populations were analyzed: th...

journal_title：Journal of the American Academy of Dermatology

authors： Menter A,Thaçi D,Papp KA,Wu JJ,Bereswill M,Teixeira HD,Rubant S,Williams DA

更新日期：2015-09-01 00:00:00

abstract：:This study compares the histopathologic characteristics of photodistributed and nonphotodistributed lichenoid drug eruptions in 13 patients. Both types have been said to be, in an unknown proportion, different from idiopathic lichen planus in that they can involve the deep as well as the superficial plexus, can contai...

journal_title：Journal of the American Academy of Dermatology

authors： West AJ,Berger TG,LeBoit PE

更新日期：1990-10-01 00:00:00

abstract：:Psoriasis has been traditionally viewed as an inflammatory skin disorder of unknown origin. Recent advances in the immunopathogenesis and genetics of psoriasis have broadened our understanding of psoriasis. Psoriasis is now considered a systemic inflammatory condition analogous to other inflammatory immune disorders. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kremers HM,McEvoy MT,Dann FJ,Gabriel SE

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Recurrences after Mohs micrographic surgery (MMS) have been associated in the past with aggressive tumor type, large tumor size, and location within certain anatomic subunits. These factors are beyond the control of the treating physician and not subject to quality improvement efforts. OBJECTIVE:We sought t...

journal_title：Journal of the American Academy of Dermatology

authors： Campbell T,Armstrong AW,Schupp CW,Barr K,Eisen DB

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Condyloma acuminatum are common lesions caused by human papillomavirus (HPV). HPV is associated with many human cancers, and a vaccine now prevents infection with high-risk HPV. However, eradication of established disease is difficult, indicating that these lesions are capable of local immunosuppression. OB...

journal_title：Journal of the American Academy of Dermatology

authors： Le Poole C,Denman CJ,Arbiser JL

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Recombinant human platelet derived growth factor-BB gel (PDGF gel) has been shown to be effective in the treatment of diabetic neuropathic ulcers. It is also being used off-label to speed wound healing of flaps, grafts, and wounds from Mohs micrographic surgery. OBJECTIVE:The purpose of the study was to com...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen MA,Eaglstein WH

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Some studies have purported to link isotretinoin prescribed for acne with the development of inflammatory bowel disease (IBD). OBJECTIVE:We sought to identify existence of disproportionate attorney-initiated reporting of isotretinoin-associated IBD in the Food and Drug Administration Adverse Event Reporting...

journal_title：Journal of the American Academy of Dermatology

authors： Stobaugh DJ,Deepak P,Ehrenpreis ED

更新日期：2013-09-01 00:00:00

abstract：:Removal of Norplant contraceptive implants may be rendered difficult by the size of the capsules and variations in insertion technique. In the standard removal technique, a single transverse incision is made close to and below the distal ends of the capsules, and a mosquito forceps is used for extraction. Described,...

journal_title：Journal of the American Academy of Dermatology

authors： Lam M,Tope WD

更新日期：1997-11-01 00:00:00

abstract：:Cutaneous extramedullary hemopoiesis (EMH) is a rare complication of chronic myeloproliferative and myelodysplastic disorders. Chronic idiopathic myelofibrosis (CIMF) is the most common underlying condition. To date, fewer than 30 cases have been reported in the literature and there has been significant confusion with...

journal_title：Journal of the American Academy of Dermatology

authors： Haniffa MA,Wilkins BS,Blasdale C,Simpson NB

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:To prevent DNA damage caused by the ultraviolet (UV) radiation of sunlight, sunscreens are commonly used to protect human skin. Current analysis of sunscreens' effectiveness is done through complicated procedures, including human exposure. OBJECTIVE:We sought to design a simple system using thymidine-thymid...

journal_title：Journal of the American Academy of Dermatology

authors： Maw KL,Caton-Williams J,Salon J,Huang Z

更新日期：2011-08-01 00:00:00

abstract：:Because Of Increasing Concern With The Ethical Challenges To Physicians In Recent Years, A Committee Of The Council Of Medical Specialty Societies (CMSS), Under The Chairmanship Of Sara C. Charles, Md, Organized A 2-DAY Symposium On The Ethic Of Medicine In April 1997. During This Conference 6 Workgroup Sessions Were ...

journal_title：Journal of the American Academy of Dermatology

authors： Sams WM

更新日期：2000-01-01 00:00:00

abstract：:Self-healing juvenile cutaneous mucinosis is an extremely uncommon disorder characterized by the acute eruption of multiple papules and subcutaneous nodules. In this report, we describe one of the youngest patients reported to date with self-healing juvenile cutaneous mucinosis and further define several of the histol...

journal_title：Journal of the American Academy of Dermatology

authors： Cowen EW,Scott GA,Mercurio MG

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Garment-related terms have been used to describe the pattern of distribution of giant congenital melanocytic nevi (GCMN). OBJECTIVE:We sought to describe patterns of distribution of GCMN and propose a classification scheme. METHODS:Photographic records of patients with GCMN from the Hospital Clinic of Barc...

journal_title：Journal of the American Academy of Dermatology

authors： Martins da Silva VP,Marghoob A,Pigem R,Carrera C,Aguilera P,Puig-Butillé JA,Puig S,Malvehy J

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Some studies have shown that switching patients from one tumor necrosis factor (TNF)-alfa inhibitor to another may be beneficial when they have an inadequate response or an adverse event. OBJECTIVE:We sought to assess the variables predicting the efficacy of the second TNF-alfa inhibitor in patients discont...

journal_title：Journal of the American Academy of Dermatology

authors： Piaserico S,Cazzaniga S,Chimenti S,Giannetti A,Maccarone M,Picardo M,Peserico A,Naldi L,Psocare Study Group.

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The negative pigment network (NPN) is seen as a negative of the pigmented network and it is purported to be a melanoma-specific structure. OBJECTIVES:We sought to assess the frequency, sensitivity, specificity, and odds ratios (ORs) of NPN between melanoma cases and a group of control lesions. METHODS:Digi...

journal_title：Journal of the American Academy of Dermatology

authors： Pizzichetta MA,Talamini R,Marghoob AA,Soyer HP,Argenziano G,Bono R,Corradin MT,De Giorgi V,Gonzalez MA,Kolm I,Kopf AW,Malvehy J,Nami N,Oliviero M,Pellacani G,Puig S,Rabinovitz H,Rubegni P,Seidenari S,Stanganelli I,

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Epidermal spongiosis with exocytosis of eosinophils (ES) has been reported in biopsy specimens from patients with various dermatoses. Its diagnostic value and the patient's outcome remain poorly understood in those cases in which ES is not associated directly with diagnostic features of a bullous dermatosis....

journal_title：Journal of the American Academy of Dermatology

authors： Ruiz E,Deng JS,Abell EA

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:It was unclear whether an increased number of common nevi (moles) predicts melanoma death. OBJECTIVE:We prospectively examined the association between number of common nevi and risk of melanoma death. METHODS:Our study used data from the Nurses' Health Study (n = 77,288 women) and Health Professionals Foll...

journal_title：Journal of the American Academy of Dermatology

authors： Li WQ,Cho E,Weinstock MA,Li S,Stampfer MJ,Qureshi AA

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Tissue-destructive and more selective cytotoxic therapies are the main methods used to treat actinic cheilitis. A topical immune stimulant, 5% imiquimod cream, has recently been used for treatment of cutaneous epithelial malignancies including squamous cell carcinoma in situ and basal cell carcinoma. OBJECT...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Germain M,Yeager J,Skelton H

更新日期：2002-10-01 00:00:00

abstract：:A 2 1/2-year-old white girl with citrullinemia accompanied by neurologic symptoms presented with 2- to 3-week loss of scalp hair. Examination of the scalp revealed 90% of the hairs to be broken off, leaving a stubble of hairs less than 1 mm in length. Microscopically, plucked hairs demonstrated flattening, twisting th...

journal_title：Journal of the American Academy of Dermatology

authors： Patel HP,Unis ME

更新日期：1985-01-01 00:00:00

abstract：:Euxyl K 400 is a preservative system for cosmetics and toiletries that contains phenoxyethanol and methyldibromoglutaronitrile in a 4:1 ratio. In The Netherlands, Italy, and Germany, the prevalence of allergy to Euxyl K 400 has risen in the past 4 years and is currently 2% to 4% in patients suspected of having contact...

journal_title：Journal of the American Academy of Dermatology

authors： De Groot AC,van Ginkel CJ,Weijland JW

更新日期：1996-11-01 00:00:00

abstract：:Unlike other mammals that molt hair seasonally, human beings have scalp hair follicles that exhibit an asynchronized pattern of cycling, with the growth and subsequent shedding of each hair being independent of others around it. This mosaic cycling behavior is established early and continues throughout life. We descri...

journal_title：Journal of the American Academy of Dermatology

authors： Thai KE,Sinclair RD

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Patients with melanoma are at increased risk for cutaneous squamous cell carcinomas (SCCs). OBJECTIVE:We sought to examine the incidence of subsequent SCC among melanoma survivors and the impact of patient and melanoma characteristics on SCC risk. METHODS:Kaiser Permanente Northern California members given...

journal_title：Journal of the American Academy of Dermatology

authors： Asgari MM,Warton EM,Quesenberry CP,Koralek DO,Taylor M

更新日期：2014-09-01 00:00:00