当前位置： SCI文献检索 > JOURNAL OF THE NEUROLOGICAL SCIENCES期刊下所有文献 > Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo).

Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo).

Abstract：

:Radiation-induced (RI) peripheral neuropathy is a rare and severe delayed complication of radiotherapy that is spontaneously irreversible, with no standard of treatment. We previously developed a successful antioxidant treatment in RI fibrosis and necrosis. Two patients with progressive worsening RI lumbosacral polyradiculopathy experienced over several years a significant clinical improvement in their neurological sensorimotor symptoms with long-term pentoxifylline-tocopherol-clodronate treatment, and good safety.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Delanian S,Lefaix JL,Maisonobe T,Salachas F,Pradat PF

doi

10.1016/j.jns.2008.08.004

subject

Has Abstract

pub_date

2008-12-15 00:00:00

pages

164-6

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(08)00383-3

journal_volume

275

pub_type

杂志文章

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