Abstract：
:A 56-year-old man, who had previously been treated for arthritis of the hands, was admitted to the hospital because of abdominal pain and fever. Physical examination, laboratory tests and liver biopsy led to the diagnosis of hemochromatosis. The patient's brother, who had also been treated for arthritis, was then found to have hemochromatosis. The patient's five children appeared to be well, but serum iron studies and HLA typing showed that four were affected with hemochromatosis.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Holcombe DJsubject
Has Abstractpub_date
1987-06-01 00:00:00pages
145-50issue
6eissn
0002-838Xissn
1532-0650journal_volume
35pub_type
杂志文章abstract：:Hoarseness is the term often used by patients to describe changes in their voice quality. The causes of hoarseness are determined after obtaining a detailed medical history of the circumstances preceding the onset of hoarseness and performing a thorough physical examination. The latter may include visualization of the...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1998-06-01 00:00:00
abstract：:A large number of drugs are introduced every year, and new interactions between medications are increasingly reported. Consequently, it is no longer practical for physicians to rely on memory alone to avoid potential drug interactions. Multiple drug regimens carry the risk of adverse interactions. Precipitant drugs mo...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2000-03-15 00:00:00
abstract：:New beta lactams and the quinolone class of antibiotics represent major improvements in the therapy of moderate to severe infections. These newer antibiotics have an extended spectrum of antimicrobial activity, excellent pharmacokinetic properties and low toxicity. The beta lactams include carbapenems, represented by ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1988-10-01 00:00:00
abstract：:Despite the widespread use of propoxyphene products as analgesics, there is no profile of a typical abuser of propoxyphene. Propoxyphene is structurally related to methadone and has central nervous system effects similar to those of opioids. The patient with dependence needs professional help in withdrawing from propo...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1985-09-01 00:00:00
abstract：:Growth hormone from human pituitary glands has been available for 30 years. Because of the scarce supply and the danger of transmitting Creutzfeldt-Jakob disease, use of the hormone was discontinued in 1984. Fortunately, synthetic growth hormone produced with recombinant DNA technology became available in 1985 and eli...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：:Vomiting, amnesia, a history of falls and other injuries, and depression and anxiety may all be clues to a drinking problem. Decreased work performance, absenteeism and difficulty in getting along with others may be present. Coming to grips with the problem is essential. Once the patient accepts the need for abstinenc...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1978-11-01 00:00:00
abstract：:Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney disease. Enlarging cysts within the kidneys are the clinical hallmark of the disease. Renal manifestations include varying degrees of kidney injury, urinary tract infections, kidney stones, and hematuria. Extrarenal manif...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVES:People with acute bronchitis may show little evidence of bacterial infection. If effective, antibiotics could shorten the course of the disease. However, if they are not effective, the risk of antibiotic resistance may be increased. The objective of this review was to assess the effects of antibiotic treatme...
journal_title：American family physician
pub_type： 杂志文章,meta分析
doi：
更新日期：2001-07-01 00:00:00
abstract：:Worry is a normal response to uncertainty. Education, empathetic support, reassurance, and passage of time usually ameliorate ordinary worries. However, these common-sense strategies for dealing with transient worries often prove ineffective for patients with excessive worry, many of whom meet the criteria for disorde...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2006-03-15 00:00:00
abstract：:The peak expiratory flow rate (PEFR) may be measured in the office or at home with an inexpensive, hand-held meter. Measurement of the PEFR provides a rapid, objective means of diagnosing and monitoring asthma. Use of the peak flow meter permits early detection of deteriorating function, allowing timely institution of...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1986-12-01 00:00:00
abstract：:Although amenorrhea may result from a number of different conditions, a systematic evaluation including a detailed history, physical examination, and laboratory assessment of selected serum hormone levels can usually identify the underlying cause. Primary amenorrhea, which by definition is failure to reach menarche, i...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2013-06-01 00:00:00
abstract：:Myocardial perfusion imaging with thallium-201 has been used extensively for many years in the evaluation of ischemic heart disease. It is a valuable adjunct to exercise treadmill testing and is especially helpful in evaluating cardiac perfusion in patients who have abnormal resting electrocardiograms, who are unable ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1993-11-01 00:00:00
abstract：:Cultures of the urine, throat and genitalia account for 90 percent of the cultures performed in an outpatient setting. The presence of a urinary tract infection, Group A beta-hemolytic streptococci or Neisseria gonorrhoeae can be ascertained easily, quickly, accurately and inexpensively in an office laboratory. Only a...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:Genetic testing may be applied in a variety of clinical situations, including preconception counseling, prenatal diagnosis and postnatal determination of genetic predisposition to disease. The family physician needs to become familiar with the full range of genetic testing possibilities in all phases of the human life...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1996-05-01 00:00:00
abstract：:Myasthenia gravis is characterized by variable ocular and skeletal muscle weakness. Peak incidence is in young women and older men. Thymomas are present in 30 percent of myasthenic patients over age 40. Binding of acetylcholine receptors by IgG antibodies may be the mechanism of the neuromuscular disorder. Repetitive ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-02-01 00:00:00
abstract：:Ischemic heart disease is one of the most common disorders managed by family physicians. Stratifying patients according to risk is important early in the course of the disease to identify patients who require invasive (percutaneous or surgical) treatment. Physical examination, clinical history, noninvasive tests and a...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1999-12-01 00:00:00
abstract：:Relactation means reestablishment of a milk supply and nursing after the cessation of nursing for a variable period. Induced nonpuerperal lactation means establishing a milk supply in a woman who has never been pregnant. When motivation and the breasts have both been carefully examined, preparation includes breast sti...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1976-08-01 00:00:00
abstract：:The term "shoulder instability" constitutes a spectrum of disorders that includes dislocation, subluxation and laxity. Anterior instability is the most common form of glenohumeral instability and may be associated with nerve injury. The diagnosis of anterior, posterior or multidirectional instability is based on a tho...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1999-05-15 00:00:00
abstract：:Adverse effects of hormonal contraceptives usually diminish with continued use of the same method. Often, physi- cians only need to reassure patients that these symptoms will likely resolve within three to five months. Long-acting injectable depot medroxyprogesterone acetate is the only hormonal contraceptive that is ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2010-12-15 00:00:00
abstract：:Acute diarrhea in adults is a common problem encountered by family physicians. The most common etiology is viral gastroenteritis, a self-limited disease. Increases in travel, comorbidities, and foodborne illness lead to more bacteria-related cases of acute diarrhea. A history and physical examination evaluating for ri...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2014-02-01 00:00:00
abstract：:Serotonin syndrome is a potentially life-threatening complication of psychopharmacologic drug therapy. The syndrome is produced most often by the concurrent use of two or more drugs that increase brainstem serotonin activity and is often unrecognized because of the varied and nonspecific nature of its symptomatology. ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1995-10-01 00:00:00
abstract：:Many patients expect to undergo screening tests for cancer. In evaluating screening procedures, physicians must take into account the known effects of lead time, length and screening biases, all of which can result in an overestimation of the benefits of screening. The gold standard by which a screening test is evalua...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2001-02-01 00:00:00
abstract：:Dorsal penile nerve block with lidocaine is safe and effective for reducing the pain associated with newborn circumcision. Administering the anesthesia adds little time or expense to the overall routine. Complications are minor, limited to local bleeding and hematoma formation. Family physicians performing circumcisio...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1991-04-01 00:00:00
abstract：:To complement the 2005 Annual Clinical Focus on medical genomics, AFP is publishing a series of short reviews on genetic syndromes. This series was designed to increase awareness of these diseases so that family physicians can recognize and diagnose children with these disorders and understand the kind of care they mi...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2005-12-01 00:00:00
abstract：:Schirmer's test is a simple, semiquantitative test of tear production. It is based on the physical tendency of a fluid to travel along a strip of porous material by capillary action due to surface tension. Sterile strips, standardized and prepackaged, are available from local scientific supply houses. The low cost and...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-11-01 00:00:00
abstract：:After the safety and the tolerable dosage range of a new drug have been determined, it must be evaluated for efficacy and safety in patients having the condition for which the new drug is intended. The nature of certain drugs or diseases of of the patient population desired may suggest a family physician as the best d...
journal_title：American family physician
pub_type： 临床试验,杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Hidradenitis suppurativa is a chronic folliculitis affecting intertriginous areas. Onset generally occurs in young adulthood to middle adulthood (18 to 39 years of age). Females and blacks are more than twice as likely to be affected. Additional risk factors include family history, smoking, and obesity. Hidradenitis s...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2019-11-01 00:00:00
abstract：:Cigarette smoking causes significant morbidity and mortality in the United States. Physicians can use the five A's framework (ask, advise, assess, assist, arrange) to promote smoking cessation. All patients should be asked about tobacco use and assessed for motivation to quit at every clinical encounter. Physicians sh...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2012-03-15 00:00:00
abstract：:The incidence of Lyme disease is increasing, and the disease is spreading geographically. Prompt diagnosis requires recognition of characteristic signs and symptoms of infection with the spirochete Borrelia burgdorferi. In more than half of cases, erythema migrans is the earliest sign of Lyme disease. Although less fr...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
abstract：:In patients with type 2 diabetes mellitus, insulin may be used to augment therapy with oral glycemic medications or as insulin replacement therapy. The American Diabetes Association suggests the use of long-acting (basal) insulin to augment therapy with one or two oral agents or one oral agent plus a glucagon-like pep...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2018-01-01 00:00:00
