Abstract：
:Many patients expect to undergo screening tests for cancer. In evaluating screening procedures, physicians must take into account the known effects of lead time, length and screening biases, all of which can result in an overestimation of the benefits of screening. The gold standard by which a screening test is evaluated remains the prospective, randomized controlled trial, demonstrating reduced morbidity and mortality. The magnitude of benefit from screening is best expressed in terms of the number of patients needed to screen. This value ranges from approximately 500 to 1,100 for proven screening interventions. These concepts are illustrated by controversies in current screening recommendations for cancers of the cervix, lung, colon, breast and prostate, which together account for more than 50 percent of cancer deaths in the United States.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Gates TJsubject
Has Abstractpub_date
2001-02-01 00:00:00pages
513-22issue
3eissn
0002-838Xissn
1532-0650journal_volume
63pub_type
杂志文章,评审abstract：:Congenital hearing loss is estimated to affect one in every 1,000 newborns. Causes of hearing loss can be conductive, sensorineural, mixed, or central. Known risk factors for congenital hearing loss include cytomegalovirus infection and premature birth necessitating a stay in the neonatal intensive care unit. However,...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2007-05-01 00:00:00
abstract：:Knee pain is a common presenting complaint with many possible causes. An awareness of certain patterns can help the family physician identify the underlying cause more efficiently. Teenage girls and young women are more likely to have patellar tracking problems such as patellar subluxation and patellofemoral pain synd...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2003-09-01 00:00:00
abstract：:Vacuum extractors have replaced forceps for many situations in which assistance is required to achieve vaginal delivery. Compared with metal-cup vacuum extractors, soft-cup devices are easier to use and cause fewer neonatal scalp injuries; however, they detach more frequently. Vacuum extractors can cause neonatal inju...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2000-09-15 00:00:00
abstract：:Methamphetamine is a stimulant commonly abused in many parts of the United States. Most methamphetamine users are white men 18 to 25 years of age, but the highest usage rates have been found in native Hawaiians, persons of more than one race, Native Americans, and men who have sex with men. Methamphetamine use produce...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2007-10-15 00:00:00
abstract：:Hospitals present a variety of infectious, chemical and physical hazards to their workers. Important pathogens include AIDS, hepatitis B and rubella viruses and Mycobacterium tuberculosis. Ethylene oxide is probably the greatest chemical hazard, but anesthetic gases, antineoplastic drugs and skin irritants or sensitiz...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：:Despite an 80 to 90 percent success rate in removing common bile duct stones, this technique has yet to receive universal acceptance in the United States. Originally developed for retained or newly formed common bile duct stones in patients with previous cholecystectomy, the procedure is now also used to remove common...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：:Low-molecular-weight heparin is a relatively recent addition to the list of therapies for prophylaxis and treatment of deep venous thrombosis (DVT). As a prophylactic, low-molecular-weight heparin is as effective as standard heparin or warfarin and does not require monitoring of the activated partial thromboplastin ti...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-15 00:00:00
abstract：:The ability to properly apply casts and splints is a technical skill easily mastered with practice and an understanding of basic principles. The initial approach to casting and splinting requires a thorough assessment of the injured extremity for proper diagnosis. Once the need for immobilization is ascertained, casti...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Pretibial myxedema is a localized dermopathy seen in patients with past or present hyperthyroidism. Massive intradermal deposition of mucin (acid mucopolysaccharide) produces the classic indurated nodules or plaques on the anterior lower legs. Most patients have elevated levels of LATS in their serum; however, this ap...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1985-05-01 00:00:00
abstract：:A systematic approach to the interpretation of ambulatory electrocardiographic recordings facilitates analysis and improves accuracy. The method suggested includes a mnemonic and a standardized interpretation form. The mnemonic facilitates recall of key technical and patient-specific parameters involved in the prepara...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:Hypothyroidism can often be misdiagnosed as psychiatric illness. The hypothyroid patient may present with depression, an organic mental disorder, apathy and/or frank psychosis (usually with paranoid symptoms). Psychiatric manifestations of the endocrinopathy will abate with thyroid hormone replacement therapy, unless ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-05-01 00:00:00
abstract：:Pharmacologic agents that attenuate the influence of the renin-angiotensin-aldosterone system are known to reduce systemic arterial blood pressure through vasodilatory action and enhanced renal clearance of sodium and water. Angiotensin-converting enzyme inhibitors are known to antagonize the renin-angiotensin-aldoste...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1996-02-01 00:00:00
abstract：:Hepatitis A is a common viral illness worldwide, although the incidence in the United States has diminished in recent years as a result of extended immunization practices. Hepatitis A virus is transmitted through fecal-oral contamination, and there are occasional outbreaks through food sources. Young children are usua...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2012-12-01 00:00:00
abstract：:Otitis externa, green nail syndrome, toe web infections, hot tub folliculitis, superinfections in chronic antibiotic-treated acne and infectious eczematoid dermatitis are examples of mild cutaneous infections due to Pseudomonas aeruginosa. These may occur in otherwise healthy persons. In persons with lowered resistanc...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Frostbite can cause loss of life and limbs. Proper treatment and follow-up care are essential in reducing morbidity and mortality. Management of the frostbite patient consists of three stages. Initial care includes protection of the extremity from trauma or partial thawing. The second stage consists of rapid rewarming...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1984-12-01 00:00:00
abstract：:Dorsal penile nerve block with lidocaine is safe and effective for reducing the pain associated with newborn circumcision. Administering the anesthesia adds little time or expense to the overall routine. Complications are minor, limited to local bleeding and hematoma formation. Family physicians performing circumcisio...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1991-04-01 00:00:00
abstract：:Although local anesthesia usually is used in surgical procedures, field or nerve blocks can provide more effective anesthesia in some situations. In a field block, local anesthetic is infiltrated around the border of the surgical field, leaving the operative area undisturbed. In field blocks, epinephrine may be added ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2004-02-01 00:00:00
abstract：:Virology has become an increasingly important field of medicine in the past decade. Many infectious diseases that were once of unknown etiology can now be linked to the specific viral pathogen. New methods for diagnosing and treating viral diseases are being developed. In addition, antiviral therapy or prophylaxis is ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1994-07-01 00:00:00
abstract：:The spondyloarthropathies include ankylosing spondylitis, reactive arthritis (including Reiter's syndrome), psoriatic arthritis, inflammatory bowel disease-associated spondyloarthropathy, and undifferentiated spondyloarthropathy. These diseases are linked by their association with the HLA-B27 gene and by the presence ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2004-06-15 00:00:00
abstract：:Analgesic and sedative needs depend on the type of procedure, the child's age and the degree of cooperation from the child and parents. Local anesthesia, which may be administered subcutaneously or in topical gel form, generally is sufficient for common procedures such as lumbar puncture and laceration repair. Frequen...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1997-02-15 00:00:00
abstract：:Primary closure of intraoral wounds can be done up to 24 hours after the injury. A mucosal seal decreases the possibility of infection and allows the wound to heal more rapidly and less painfully than a wound left open to heal by secondary intention. Defects of the lips must be closed with exact alignment of the vermi...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1978-11-01 00:00:00
abstract：:Ginger (Zingiber officinale) is one of the more commonly used herbal supplements. Although often consumed for culinary purposes, it is taken by many patients to treat a variety of conditions. Ginger has been shown to be effective for pregnancy-induced and postoperative nausea and vomiting. There is less evidence to su...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2007-06-01 00:00:00
abstract：:Family physicians should be aware of the potential effects and complications of vasectomy so they can appropriately counsel patients seeking sterilization. Vasectomy produces anatomic, hormonal and immunologic changes and, although not substantiated by clinical studies, has been reputed to be associated with atheroscl...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1993-11-15 00:00:00
abstract：:Although early management of children with hearing loss is extremely important, diagnosis is often delayed because the development of hearing-impaired children parallels that of normal infants until the age of nine months. A high-risk registry aids in recognition of hearing-impaired children, but fails to identify tho...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1980-03-01 00:00:00
abstract：:Myocardial infarction and congestive heart failure are associated with high morbidity and mortality rates. The results of recent clinical trials support a beneficial role for angiotensin-converting enzyme (ACE) inhibitors in attenuating mortality from myocardial infarction and left ventricular dysfunction. Large-scale...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1995-11-01 00:00:00
abstract：:Patients with type 2 diabetes (formerly known as non-insulin-resistant diabetes) have a significantly increased risk of developing cardiovascular disease. Once clinical cardiovascular disease develops, these patients have a poorer prognosis than normoglycemic patients. By inducing endothelial changes, hyperglycemia co...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-15 00:00:00
abstract：:Many patients in primary care present with ear pain (otalgia). When the ear is the source of the pain (primary otalgia), the ear examination is usually abnormal. When the ear is not the source of the pain (secondary otalgia), the ear examination is typically normal. The cause of primary otalgia is usually apparent on ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2008-03-01 00:00:00
abstract：:The clinical course is highly variable. The chance of recurrence is about 60 percent. Patients are infectious when lesions are present and, to a lesser extent, when asymptomatic virus shedding occurs. The chain of transmission can be difficult to ascertain. Transmission to the neonate is the most feared complication. ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
abstract：:Common anorectal disorders can produce one or more of the following symptoms: pain, protrusion, pruritus, bleeding or discharge. The cause may be cryptitis, anal fissure, hemorrhoids, anorectal abscess, fistula in ano, neoplasm, condylomata acuminata, pilonidal cyst or inflammatory bowel disease. Each disorder is sugg...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1980-10-01 00:00:00
abstract：:The prevalence of childhood obesity in the United States has risen dramatically in the past several decades. Although 25 to 30 percent of children are affected, this condition is underdiagnosed and undertreated. Hormonal and genetic factors are rarely the cause of childhood obesity; unnecessary diagnostic evaluations ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1999-02-15 00:00:00
