Abstract:
:An immunohistologic study was performed on temporal bones from 30 LP/J mice and 17 CBA/J mice to assess the role of immunologic injury in the pathogenesis of dysplastic bony lesions in LP/J mice. Temporal bones were harvested from animals aged 2 to 31 months to evaluate the progression of the disease. As early as 2 months of age, before the onset of bony lesions, the tympanic cavities frequently contained small effusions coating the ossicles and otic capsules that were demonstrated to contain immunoglobulins and pockets of macrophages. Later in the course of the disease, bony lesions grossly and histologically similar to human otosclerosis developed, which stained for immunoglobulins. No similar bony lesions, effusions, cellular infiltrates, or staining for immunoglobulins was detected in the control animals, even in the presence of acute otitis media. This study suggests a role of immunologic injury in the pathogenesis of dysplastic bony lesions in LP/J mice.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Brodie HA,Chole RAdoi
10.1016/s0196-0709(87)80053-4subject
Has Abstractpub_date
1987-09-01 00:00:00pages
342-50issue
5eissn
0196-0709issn
1532-818Xpii
S0196-0709(87)80053-4journal_volume
8pub_type
杂志文章abstract:PURPOSE:The study objective is to evaluate the clinical features and outcomes of patients treated for head and neck malignant fibrous histiocytoma at a tertiary care medical facility. MATERIALS AND METHODS:This is a retrospective case series of 17 adult subjects with malignant fibrous histiocytoma of the head and neck...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2012.06.010
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:To determine whether inclusion of chemoradiation history increases estimated risk for complications following total laryngectomy using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) Surgical Risk Calculator. MATERIALS AND METHODS:A retrospective review of 96 patients wit...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2017.11.005
更新日期:2018-01-01 00:00:00
abstract::Two cases of inner ear injury caused by suppressed sneezing are described. One patient experienced vestibular symptoms in the form of reflexogenic vertigo that was relieved by surgical section of the tensor tympani tendon. The other patient had a sudden severe permanent sensorineural hearing loss. It is proposed that ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(85)80027-2
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:Primary non-Hodgkin lymphomas (NHLs) of the sinonasal tract comprise a rare entity that constitutes 1.5% of all NHLs and 2.2% of extranodal lymphomas in the whites. Clinical diagnosis may be very challenging because of the variety and low specificity of the presenting symptoms and signs. METHODS-RESULTS:We ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2005.09.019
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of adding platelet rich plasma (PRP) or Hyaluronic acid (HA) to fat graft myringoplasty (FGM) for medium sized central tympanic membrane (TM) perforations. METHODS:This is a retrospective study conducted on 69 patients with medium sized central TM perforations. In 21 patients, PRP was...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2018.08.004
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To investigate objective measures that could increase the positive predictive value of computed tomography (CT) in diagnosing deep neck space infections (DNSIs). METHODS:A retrospective analysis of patients surgically treated at a tertiary care hospital for DNSIs for more than 2 years were reviewed. Patients w...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2005.11.008
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:To evaluate the relationship between facial cephalometric measures and response to uvulopalatopharyngoplasty (UPPP). PATIENTS AND METHODS:Retrospective analysis of skeletal cephalometric measures obtained from a consecutive sample of 43 patients with obstructive sleep apnea syndrome (OSAS) who underwent body m...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(97)90079-x
更新日期:1997-05-01 00:00:00
abstract::Ectopic thyroid is a rare developmental anomaly. It can be found anywhere between the foramen cecum and the normal position of the thyroid gland. Massive bleeding from an ectopic lingual thyroid is unusual and occasionally fatal. We present a case of a 22-year-old woman who had a large mass at the base of the tongue f...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1053/ajot.2002.123432
更新日期:2002-05-01 00:00:00
abstract::Zygomatic hemangioma is an extremely rare, benign, slow-growing tumor occurring mostly in adult women. The radiologic findings are diagnostic. Total excision of the tumor with primary reconstruction of the defect is the preferred treatment modality. We present a case of zygomatic hemangioma and a brief review of the l...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s0196-0709(02)32429-3
更新日期:2003-05-01 00:00:00
abstract::Purulent otitis media was induced in 12 middle ears of Sprague-Dawley rats by inoculation of pneumococci type 3. The pressure required to open the eustachian tube was recorded 4 days later and was found to be 3.05 +/- 0.10 kPa (mean +/- SEM), which was 1.08 +/- 0.15 kPa lower than the mean value obtained in a control ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/0196-0709(90)90117-e
更新日期:1990-11-01 00:00:00
abstract:PURPOSE:The current loss to follow-up rate after failed newborn hearing screening (NBHS) is 34.4%. Previous studies have found that lack of parental and primary care provider (PCP) awareness of NBHS results are significant contributors to loss to follow-up. The objective of this study was to identify factors associated...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102614
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To investigate the correlation between internet search activity and epistaxis-related Emergency Department visits. MATERIALS AND METHODS:Data from Google Trends were obtained (www.google.com/trends) for the search term "nosebleed" in Erie County, Pennsylvania during a five-year period. All epistaxis-related CP...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2018.07.012
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:Idiopathic sudden sensorineural hearing loss (ISSHL) is an emergency otological disease, and its definite prognostic factors remain unclear. This study applied machine learning methods to develop a new ISSHL prognosis prediction model. MATERIALS AND METHODS:This retrospective study reviewed the medical data of...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102858
更新日期:2021-01-04 00:00:00
abstract:PURPOSE:To report the result of transcanal tympanoplasty using Lyodura as a graft. MATERIALS AND METHODS:One hundred thirty-seven patients with chronic suppurative otitis media with a dry perforation were considered for tympanoplasty. The transcanal permeatal approach was adopted. Lyodura as a ready-made graft was use...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(99)90000-5
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:The purpose of this retrospective cohort study was to determine whether there is a difference in the sensitivity of chest computed tomography (CT) versus 18F-fluorodeoxyglucose positron emission tomography with low-dose nonenhanced CT (18F-FDG PET/CT or PET/CT) in the detection of distant metastases in head and...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102662
更新日期:2020-01-01 00:00:00
abstract::Sarcomatoid carcinomas of the larynx account for less than 1% of all malignant laryngeal tumors and there is currently no consensus regarding the clinical course or appropriate management of this disease. A case of sarcomatoid carcinoma of the larynx displaying rapid systemic progression after radiotherapy and a brief...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2005.02.017
更新日期:2005-11-01 00:00:00
abstract::We aimed to investigate the relationship between peripheral vertigo and inflammation by using the neutrophil-to-lymphocyte ratio (NLR) as an inflammatory marker. We recruited 103 patients with peripheral vertigo (71 women, 32 men; mean age, 39.8 ± 14.7 years) who presented to the Otolaryngology Department of Dumlupina...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2014.08.004
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:In pituitary macroadenomas with extensive suprasellar extension (SSE), suprasellar region can be approached by extending exposure either anteriorly by adding bone removal of the tuberculum sellae and planum sphenoidal or posteriorly from inside the sellar cavity through diaphragma sella. The later approach ha...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102808
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:Tracheostomy is commonly used to provide control of the upper airway in pediatric patients. The traditional approach, which uses a midline vertical incision in the anterior tracheal wall, is associated with relatively high rates of complications when it is used on a long-term basis. Alternative approaches, such...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(96)90090-3
更新日期:1996-07-01 00:00:00
abstract:PURPOSE:The aim of this article is to present the development of brown tumors in the jaws as a definite feature of hyperparathyroidism (HPT), whether primary or secondary. PATIENTS AND METHODS:The study included 2 cases of primary HPT and 3 cases of secondary HPT associated with brown tumors in the jaws. The patients ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2005.11.004
更新日期:2006-07-01 00:00:00
abstract::Meniere's disease is a peripheral audiovestibular disorder characterized by vertigo, hearing loss, tinnitus, and aural fullness. Management of these symptoms includes medical and surgical treatment. Many patients with Meniere's disease can be managed using nonablative therapy, such as intratympanic steroids and endoly...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2020.102817
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:Edema of the arytenoid and wound hematoma are principal causes of inspiratory distress after arytenoid adduction and type I thyroplasty. The purpose of the present study was demonstrate esophageal regurgitation one of the causes of inspiratory distress after thyroplastic surgeries. STUDY DESIGN:Two case rep...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2006.01.017
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:The clinical use of aminoglycoside antibiotics is limited in most countries because of auditory toxicity side effects. However, their use is common in developing countries because they are inexpensive and convenient. Salvia miltiorrhiza extracts are used clinically in China for their antioxidant properties. W...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.08.022
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Cluster schedule of allergen-specific immunotherapy (AIT) is a cost-effective choice for allergic rhinitis (AR) patients, but its safety has been questioned due to the greater dosages required at each treatment compared with conventional immunotherapy. It remains a question that whether cluster schedule lead...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,meta分析
doi:10.1016/j.amjoto.2019.07.013
更新日期:2019-01-01 00:00:00
abstract::Previous studies have shown that propylene glycol causes inflammatory changes and cholesteatoma when applied to chinchilla middle ears. Vitamin A and synthetic analogues are essential for the normal differentiation of epithelial tissues. The purpose of this study was to determine whether the administration of isotreti...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/0196-0709(90)90163-p
更新日期:1990-01-01 00:00:00
abstract::Rupture of the carotid artery has been one of the most feared postoperative complications in head and neck cancer patients. Traditional management of carotid artery rupture has been disappointing, and morbidity and mortality have been high. Experience with carotid artery rupture at the authors' institution over the pa...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(86)80009-6
更新日期:1986-05-01 00:00:00
abstract::We present 3 patients who complained of distorted hearing, tinnitus and otalgia resulting from scalp and facial hair impacting against the tympanic membrane. Removal of the migrated hair with microsuction relieved symptoms immediately. In 2 cases, the patients had presented to the primary care physician earlier, short...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.09.005
更新日期:2014-03-01 00:00:00
abstract::Branhamella catarrhalis has gained increasing recognition as a pathogen in the respiratory tract. During the past 18 years, since its transfer from the genus Neisseria, it has been associated with infection in cavities of the respiratory tract (sinuses and middle ear). It has been recognized as playing a role in laryn...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/0196-0709(91)90046-i
更新日期:1991-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare the quality of life (QoL) of adult CI users with the QoL of adults in the healthy and normal-hearing population. MATERIALS AND METHODS:31 patients with CIs were included in the CI group, and 31 normal-hearing subjects were included in the control group. The QoL was evaluate...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2019.06.010
更新日期:2019-01-01 00:00:00
abstract::The endometrial small cell carcinoma (ESCC) is a rare and aggressive malignancy with an estimated prevalence of less than 1% of endometrial carcinomas. Endometrial small cell carcinoma is frequently diagnosed at an advanced stage and has a poor prognosis. Although the most common presenting sign of ESCC is definitely ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2006.09.011
更新日期:2007-07-01 00:00:00