Abstract:
:The DNA sequence of the human beta-globin region, comprising over 67 kilobase pairs, has been analyzed for the occurrence of strings of contiguous purine or pyrimidine residues. Tracts of 10 or more contiguous residues are found 4 times more frequently than would be expected with a random distribution of bases, so that a long string occurs at an average of every 250 base pairs. A survey of six other human gene sequences, totaling 86 kilobase pairs, shows a remarkably similar result. No such overrepresentation of contiguous purine or pyrimidine residues is found in the bacteriophages lambda or T7.
journal_name
Biochemistryjournal_title
Biochemistryauthors
Behe MJdoi
10.1021/bi00398a050subject
Has Abstractpub_date
1987-12-01 00:00:00pages
7870-5issue
24eissn
0006-2960issn
1520-4995journal_volume
26pub_type
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