当前位置： SCI文献检索 > DEVELOPMENTAL BIOLOGY期刊下所有文献 > Development of myoplasm-enriched ascidian embryos.

Development of myoplasm-enriched ascidian embryos.

Abstract：

:The fertilized ascidian egg is thought to be comprised of distinct regions of tissue-specific cytoplasmic determinants. This idea was tested by bisecting fertilized eggs into egg fragments and culturing them until the unoperated controls developed into larvae. Fertilized eggs were bisected using a microsurgical method in which part of the uncleaved zygote was extruded through a hole made in the follicular envelope and the cytoplasmic bridge between the two egg regions was severed. One egg fragment contained all of the egg myoplasm (termed myoplasm-enriched or ME fragment), while the other fragment lacked myoplasm. ME fragments consisting of 40-50% of the total egg volume in many cases cleaved normally and developed into larvae. In a few cases, ME larvae initiated metamorphosis and developed into normal juveniles. Triton-extraction of ME embryos and larvae showed that the myoplasm was redistributed into nonmuscle lineage cells at each stage of development. Despite the redistribution of myoplasm into many of the endoderm cells situated in the head region of ME larvae, the expression of the muscle-specific enzyme acetylcholinesterase (AchE) and a muscle-specific antigen (Mu-2) was restricted to the tail muscle cells. The endoderm cells situated in the head region of ME larvae expressed an endoderm-specific enzyme alkaline phosphatase (AP) as in the controls. Furthermore, cleavage-arrested four- and eight-cell ME embryos expressed AchE activity in the expected number of blastomeres. When a greater quantity of myoplasm was redistributed into cells that normally do not express AchE activity by producing 10-30% ME embryos, in a few cases more than the expected number of blastomeres expressed AchE activity. In conclusion, the main finding of the present investigation, based on the development of ME fragments comprising 40-50% of the total egg volume, is that ascidian embryos are capable of regulative development.

journal_name

Dev Biol

journal_title

Developmental biology

authors

Bates WR

doi

10.1016/0012-1606(88)90178-9

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

241-52

issue

1

eissn

0012-1606

issn

1095-564X

pii

0012-1606(88)90178-9

journal_volume

129

pub_type

杂志文章

相关文献

DEVELOPMENTAL BIOLOGY文献大全
  • Regulation of cyclin A localization downstream of Par-1 function is critical for the centrosome orientation checkpoint in Drosophila male germline stem cells.

    abstract：:Male germline stem cells (GSCs) in Drosophila melanogaster divide asymmetrically by orienting the mitotic spindle with respect to the niche, a microenvironment that specifies stem cell identity. The spindle orientation is prepared during interphase through stereotypical positioning of the centrosomes. We recently demo...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2011.10.010

    authors： Yuan H,Chiang CY,Cheng J,Salzmann V,Yamashita YM

    更新日期：2012-01-01 00:00:00

  • Dependence of myoblast fusion on a cortical actin wall and nonmuscle myosin IIA.

    abstract：:Cell-cell fusion is a fundamental cellular process that is essential for development as well as fertilization. Myoblast fusion to form multinucleated skeletal muscle myotubes is a well studied, yet incompletely understood example of cell-cell fusion that is essential for formation of contractile skeletal muscle tissue...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2008.10.035

    authors： Duan R,Gallagher PJ

    更新日期：2009-01-15 00:00:00

  • O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

    abstract：:Thrombospondin type 1 repeat (TSR) superfamily members regulate diverse biological activities ranging from cell motility to inhibition of angiogenesis. In this study, we verified that mouse protein O-fucosyltransferase-2 (POFUT2) specifically adds O-fucose to TSRs. Using two Pofut2 gene-trap lines, we demonstrated tha...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2010.07.008

    authors： Du J,Takeuchi H,Leonhard-Melief C,Shroyer KR,Dlugosz M,Haltiwanger RS,Holdener BC

    更新日期：2010-10-01 00:00:00

  • Inhibition by dibutyryl cyclic AMP of the transition to metaphase of mouse oocyte nuclei and its reversal by cell fusion to metaphase oocytes.

    abstract：:Mouse oocytes at metaphase I of meiotic maturation were treated with puromycin, which caused the condensed chromosomes to become decondensed to form an interphase nucleus. The chromosomes returned to a metaphase state 6.3 hr after the oocytes were transferred to puromycin-free medium [H. J. Clarke and Y. Masui (1983) ...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(85)90006-5

    authors： Clarke HJ,Masui Y

    更新日期：1985-03-01 00:00:00

  • Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation.

    abstract：:The mammalian thalamus is an essential diencephalic derivative that plays unique roles in processing and relaying sensory and motor information to and from the cerebral cortex. The profile of transcription factors and lineage tracing experiments revealed a spatiotemporal relationship between diencephalic progenitor do...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2014.12.003

    authors： Song H,Lee B,Pyun D,Guimera J,Son Y,Yoon J,Baek K,Wurst W,Jeong Y

    更新日期：2015-02-15 00:00:00

  • Translational regulation of the novel haploid-specific transcripts for the c-abl proto-oncogene and a member of the 70 kDa heat-shock protein gene family in the male germ line.

    abstract：:Expression of the c-abl proto-oncogene in the mouse testis is characterized by the production of a unique 4.7-kb transcript present in germ cells that have entered the haploid phase of spermatogenesis. A similar developmental stage specificity of expression is observed for a member of the 70-kDa heat-shock protein (hs...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(88)90222-9

    authors： Zakeri ZF,Ponzetto C,Wolgemuth DJ

    更新日期：1988-02-01 00:00:00

  • Protein kinase D regulates metabolism and growth by controlling secretion of insulin like peptide.

    abstract：:Mechanisms coupling growth and metabolism are conserved in Drosophila and mammals. In metazoans, such coupling is achieved across tissue scales through the regulated secretion of chemical messengers such as insulin that control the metabolism and growth of cells. Although the regulated secretion of Insulin like peptid...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2017.12.008

    authors： Ashe S,Malhotra V,Raghu P

    更新日期：2018-02-01 00:00:00

  • Roles for scalloped and vestigial in regulating cell affinity and interactions between the wing blade and the wing hinge.

    abstract：:The scalloped and vestigial genes are both required for the formation of the Drosophila wing, and recent studies have indicated that they can function as a heterodimeric complex to regulate the expression of downstream target genes. We have analyzed the consequences of complete loss of scalloped function, ectopic expr...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.2000.9939

    authors： Liu X,Grammont M,Irvine KD

    更新日期：2000-12-15 00:00:00

  • Accumulation kinetics of cotton late embryogenesis-abundant mRNAs and storage protein mRNAs: coordinate regulation during embryogenesis and the role of abscisic acid.

    abstract：:The accumulation of total RNA transcripts of 18 late embryo-abundant (Lea) gene families, each encoding two closely related Lea mRNAs, was measured in cotyledon total RNA during embryogenesis and germination of Gossypium hirsutum L. by RNA dot hybridization. Transcript abundance of the three storage protein families w...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(87)90442-8

    authors： Galau GA,Bijaisoradat N,Hughes DW

    更新日期：1987-09-01 00:00:00

  • The b-HLH transcription factor Hes3 participates in neural plate border formation by interfering with Wnt/β-catenin signaling.

    abstract：:Hes3 belongs to the Hes basic helix-loop-helix family of transcriptional repressors that play central roles in maintaining progenitor cells and regulating binary cell fate decisions in the embryo. During Xenopus laevis development, hes3 is expressed in the embryonic ectoderm in a horseshoe shape domain at the edge of ...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2018.07.011

    authors： Hong CS,Saint-Jeannet JP

    更新日期：2018-10-01 00:00:00

  • Developmentally regulated expression of temporally distinct beta-glucosidase isozymes in Dictyostelium discoideum.

    abstract：:During development of Dictyostelium discoideum, the cellular specific activity of beta-glucosidase increases before aggregation, declines to low levels during pseudoplasmodium formation, and increases rapidly during culmination. In addition, two electrophoretically distinct isozymes of beta-glucosidase are present at ...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(87)90407-6

    authors： Golumbeski GS Jr,Dimond RL

    更新日期：1987-10-01 00:00:00

  • Widespread tangential dispersion and extensive cell death during early neurogenesis in the mouse neocortex.

    abstract：:The development of the mammalian neocortex requires radial and tangential migration of cells. Radial migration of differentiated neurons from the ventricular zone (VZ) is well established. It is hypothesised that an earlier phase of tangential migration of mitotically active cells lays down a widespread periodically s...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2003.11.006

    authors： Wilkie AL,Jordan SA,Sharpe JA,Price DJ,Jackson IJ

    更新日期：2004-03-01 00:00:00

  • Boundary maintenance in the ancestral metazoan Hydra depends on histone acetylation.

    abstract：:Much of boundary formation during development remains to be understood, despite being a defining feature of many animal taxa. Axial patterning of Hydra, a member of the ancient phylum Cnidaria which diverged prior to the bilaterian radiation, involves a steady-state of production and loss of tissue, and is dependent o...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2019.11.006

    authors： López-Quintero JA,Torres GG,Neme R,Bosch TCG

    更新日期：2020-02-15 00:00:00

  • Radial leaves of the maize mutant ragged seedling2 retain dorsiventral anatomy.

    abstract：:ragged seedling2 (rgd2) is a novel, recessive mutation affecting lateral organ development in maize. The mutant phenotype of homozygous rgd2-R leaves is variable. Mild leaf phenotypes have a reduced midrib and may be moderately narrow and furcated; severe Rgd2-R(-) leaves are filamentous or even radial. Despite their ...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2005.03.027

    authors： Henderson DC,Muehlbauer GJ,Scanlon MJ

    更新日期：2005-06-15 00:00:00

  • States of determination of single cells transplanted between 512-cell Xenopus embryos.

    abstract：:Single cells from 512-cell Xenopus embryos, totally labeled with intracellular horseradish peroxidase, were transplanted orthotopically (from either dorsal or lateral marginal zone) or heterotopically (between these two marginal zones) to unlabeled host embryos at the 512-cell stage. At tailbud stage 23 the locations,...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/s0012-1606(89)80043-0

    authors： Jacobson M,Xu WL

    更新日期：1989-01-01 00:00:00

  • Regulation of M-phase progression in Chaetopterus oocytes by protein kinase C.

    abstract：:We have examined the presence of protein kinase C in oocytes of Chaetopterus pergamentaceus and its role in the initiation of germinal vesicle breakdown (GVBD). First, we demonstrated that the oocytes contain a phospholipid- and calcium-dependent protein kinase, protein kinase C (PKC). Since PKC is the primary intrace...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(92)90294-q

    authors： Eckberg WR,Palazzo RE

    更新日期：1992-02-01 00:00:00

  • Signals from the dorsal blastopore lip region during gastrulation bias the ectoderm toward a nonepidermal pathway of differentiation in Xenopus laevis.

    abstract：:Epi 1, a monoclonal antibody, was generated against an epidermal specific epithelial antigen; it does not stain neural epithelium. We have used Epi 1 as a marker to determine when the spatial patterns delineating neural from nonneural epithelium become established. We used ventral ectoderm in a sandwich assay to show ...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(89)90307-2

    authors： Savage R,Phillips CR

    更新日期：1989-05-01 00:00:00

  • An organizing role for the TGF-β signaling pathway in axes formation of the annelid Capitella teleta.

    abstract：:Embryonic organizers are signaling centers that coordinate developmental events within an embryo. Localized to either an individual cell or group of cells, embryonic organizing activity induces the specification of other cells in the embryo and can influence formation of body axes. In the spiralian Capitella teleta, p...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2018.01.004

    authors： Lanza AR,Seaver EC

    更新日期：2018-03-01 00:00:00

  • Wnt6 signaling regulates heart muscle development during organogenesis.

    abstract：:Mesodermal tissue with heart forming potential (cardiogenic mesoderm) is induced during gastrulation. This cardiogenic mesoderm later differentiates into heart muscle tissue (myocardium) and non-muscular heart tissue. Inhibition of Wnt/beta-catenin signaling is known to be required early for induction of cardiogenic m...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2008.08.032

    authors： Lavery DL,Martin J,Turnbull YD,Hoppler S

    更新日期：2008-11-15 00:00:00

  • A hypomorphic myogenin allele reveals distinct myogenin expression levels required for viability, skeletal muscle development, and sternum formation.

    abstract：:The myogenic basic helix-loop-helix transcription factor myogenin plays an essential role in the differentiation of skeletal muscle and, secondarily, in rib and sternum formation during mouse development. However, virtually nothing is known about the quantitative requirements for myogenin in these processes. Here, we ...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1006/dbio.1998.9182

    authors： Vivian JL,Gan L,Olson EN,Klein WH

    更新日期：1999-04-01 00:00:00

  • Different molecular mechanisms for cAMP regulation of gene expression during Dictyostelium development.

    abstract：:Alterations in cAMP concentrations have been implicated in developmentally regulated gene expression in Dictyostelium. Using a variety of culture conditions to control the metabolism of cAMP during cytodifferentiation, I have examined the role of the cyclic nucleotide in development. Conditions which allow intracellul...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(87)90342-3

    authors： Kimmel AR

    更新日期：1987-07-01 00:00:00

  • Mef2c factors are required for early but not late addition of cardiomyocytes to the ventricle.

    abstract：:During heart formation, the heart grows and undergoes dramatic morphogenesis to achieve efficient embryonic function. Both in fish and amniotes, much of the growth occurring after initial heart tube formation arises from second heart field (SHF)-derived progenitor cell addition to the arterial pole, allowing chamber f...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2020.11.008

    authors： Kula-Alwar D,Marber MS,Hughes SM,Hinits Y

    更新日期：2021-02-01 00:00:00

  • Gcm proteins function in the developing nervous system.

    abstract：:A fundamental issue during nervous system development is how individual cells are formed from the undefined precursors. Differentiated neurons and glia, two major cell types mediating neuronal function, are acquired from immature precursors via a series of explicit controls exerted by transcription factors such as pro...

    journal_title：Developmental biology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ydbio.2012.07.018

    authors： Mao H,Lv Z,Ho MS

    更新日期：2012-10-01 00:00:00

  • Pax8 and Pax2 are specifically required at different steps of Xenopus pronephros development.

    abstract：:The respective role of Pax2 and Pax8 in early kidney development in vertebrates is poorly understood. In this report, we have studied the roles of Pax8 and Pax2 in Xenopus pronephros development using a loss-of-function approach. Our results highlight a differential requirement of these two transcription factors for p...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2014.10.022

    authors： Buisson I,Le Bouffant R,Futel M,Riou JF,Umbhauer M

    更新日期：2015-01-15 00:00:00

  • Transcriptional repressor and activator activities of SMA-9 contribute differentially to BMP-related signaling outputs.

    abstract：:In the nematode Caenorhabditis elegans, the BMP-related growth factor DBL-1 regulates body size and male tail morphogenesis via a conserved receptor/Smad signaling pathway. Smads are transcription factors, but rely on transcription cofactors for appropriate regulation of target genes in response to TGF-beta- and BMP-r...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2007.02.038

    authors： Liang J,Yu L,Yin J,Savage-Dunn C

    更新日期：2007-05-15 00:00:00

  • Differentiation of nonbeating embryonic stem cells into beating cardiomyocytes is dependent on downregulation of PKC beta and zeta in concert with upregulation of PKC epsilon.

    abstract：:Cardiomyocyte differentiation overall has been analyzed in vivo and in vitro at the molecular level by homologous recombination, gene mutation studies, and by transgenics; however, the roles of many signal transduction mechanisms that drive this differentiation process are still not fully understood. One set of signal...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/s0012-1606(02)00080-5

    authors： Zhou X,Quann E,Gallicano GI

    更新日期：2003-03-15 00:00:00

  • FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development.

    abstract：:FOG-2 is a multi-zinc finger protein that binds the transcriptional activator GATA4 and modulates GATA4-mediated regulation of target genes during heart development. Our previous work has demonstrated that the Nucleosome Remodeling and Deacetylase (NuRD) complex physically interacts with FOG-2 and is necessary for FOG...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2014.08.030

    authors： Garnatz AS,Gao Z,Broman M,Martens S,Earley JU,Svensson EC

    更新日期：2014-11-01 00:00:00

  • Reduced Abd-B Hox function during kidney development results in lineage infidelity.

    abstract：:Hox genes can function as key drivers of segment identity, with Hox mutations in Drosophila often resulting in dramatic homeotic transformations. In addition, however, they can serve other essential functions. In mammals, the study of Hox gene roles in development is complicated by the presence of four Hox clusters wi...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2018.03.020

    authors： Magella B,Mahoney R,Adam M,Potter SS

    更新日期：2018-06-15 00:00:00

  • Defective adult oligodendrocyte and Schwann cell development, pigment pattern, and craniofacial morphology in puma mutant zebrafish having an alpha tubulin mutation.

    abstract：:The processes of myelination remain incompletely understood but are of profound biomedical importance owing to the several dysmyelinating and demyelinating disorders known in humans. Here, we analyze the zebrafish puma mutant, isolated originally for pigment pattern defects limited to the adult stage. We show that pum...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/j.ydbio.2010.07.035

    authors： Larson TA,Gordon TN,Lau HE,Parichy DM

    更新日期：2010-10-15 00:00:00

  • Alkaline phosphatase expression in ascidian egg fragments and andromerogons.

    abstract：:Alkaline phosphatase (AP) activity is expressed in the endodermal cell lineage of ascidian embryos beginning at gastrulation. AP expression is resistant to levels of actinomycin D which completely suppress the appearance of other tissue-specific enzyme and morphological markers including acetylcholinesterase (AchE), a...

    journal_title：Developmental biology

    pub_type： 杂志文章

    doi：10.1016/0012-1606(87)90043-1

    authors： Bates WR,Jeffery WR

    更新日期：1987-02-01 00:00:00