The association between heart rate and glycemia in adult diabetic subjects.

Abstract:

:We have studied the association between heart rate and glycemia in 221 diabetic and 109 non-diabetic adult subjects. Supine and standing heart rates were both statistically significantly higher (P less than 0.001) in the diabetic patients than in the control subjects. Among the diabetics, both the supine and standing heart rates were positively associated with hemoglobin A1c (r = 0.26, P less than 0.001 and r = 0.27, P less than 0.001 respectively). Patients with hemoglobin A1c values greater than 10.00% had a mean heart rate of 84.2 +/- 2.4, while those with hemoglobin A1c values less than 6.00% had a mean of 74.0 +/- 1.5 (P less than 0.001). The associations between heart rate and hemoglobin A1c persisted (P less than 0.001) with allowances for potential confounding variables in multiple regression analyses. The 15:30 difference, an indicator of parasympathetic function, was not associated with either heart rate or glycemia. These data suggest that the heart rate elevation in adult diabetic patients is the result of metabolic abnormalities.

authors

Gadia MT,Skyler JS,Sosenko JM

doi

10.1016/s0168-8227(88)80074-3

subject

Has Abstract

pub_date

1988-05-19 00:00:00

pages

25-9

issue

1

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(88)80074-3

journal_volume

5

pub_type

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