Lung imaging under free-breathing conditions.

abstract：:The ability to generate in vivo maps of lactate may have significant diagnostic utility in staging and treatment planning of a wide variety of cancers. The double selective multiple quantum filter technique (SelMQC) has been shown to be effective for nonlocalized detection of lactate with little or no interference fro...

journal_title：Magnetic resonance in medicine

authors： Pickup S,Lee SC,Mancuso A,Glickson JD

更新日期：2008-08-01 00:00:00

abstract：:A previously developed eigenvector formalism is adapted to off-resonance in the transient response of quasiperiodic steady-state free precession (SSFP) sequences, including TrueFISP as a special case. The effective relaxation rates for essentially parallel and perpendicular deviations from the steady state are determi...

journal_title：Magnetic resonance in medicine

authors： Ganter C

更新日期：2004-08-01 00:00:00

abstract：:The pulse wave velocity (PWV) of aortic blood flow is considered a surrogate for aortic compliance. A new method using phase-contrast (PC)-MRI is presented whereby the spatial and temporal profiles of axial velocity along the descending aorta can be analyzed. Seventeen young healthy volunteers (the YH group), six olde...

journal_title：Magnetic resonance in medicine

authors： Yu HY,Peng HH,Wang JL,Wen CY,Tseng WY

更新日期：2006-10-01 00:00:00

abstract：:Detre et al. (Magn. Reson. Med. 23, 37-45 (1992)) and Zhang et al., (Magn. Reson. Med. 25, 362 (1992)) have recently demonstrated a technique for the measurement of regional cerebral blood flow (rCBF) based on the continuous saturation (or inversion) of the arterial blood supply to the brain in rats at 4.7 T. In the w...

journal_title：Magnetic resonance in medicine

authors： Walsh EG,Minematsu K,Leppo J,Moore SC

更新日期：1994-02-01 00:00:00

abstract：PURPOSE:To investigate the effect of realistic microstructural geometry on the susceptibility-weighted MR signal in white matter (WM), with application to demyelination. METHODS:Previous work has modeled susceptibility-weighted signals under the assumption that axons are cylindrical. In this study, we explored the imp...

journal_title：Magnetic resonance in medicine

authors： Xu T,Foxley S,Kleinnijenhuis M,Chen WC,Miller KL

更新日期：2018-01-01 00:00:00

abstract：:The MMQ cell line is a unique prolactin-secreting rat pituitary cell line. MMQ cells entrapped in agarose gel threads are metabolically active, as determined by the uptake and phosphorylation of creatine and the maintenance of high energy phosphates for over 15 h. Forskolin activates the catalytic subunit of adenylyl ...

journal_title：Magnetic resonance in medicine

authors： Goger MJ,Login IS,Fernandez EJ,Grisham CM

更新日期：1994-11-01 00:00:00

abstract：:Short image acquisition times and sensitivity to magnetic susceptibility favor the use of gradient echo imaging methods in functional MRI (fMRI). However, magnetic susceptibility effects attributed to air-tissue interfaces also lead to severe signal loss in images of the large inferior frontal and lateral temporal cor...

journal_title：Magnetic resonance in medicine

authors： Yang QX,Dardzinski BJ,Li S,Eslinger PJ,Smith MB

更新日期：1997-03-01 00:00:00

abstract：:In echo-planar-based diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI), the evaluation of diffusion parameters such as apparent diffusion coefficients and anisotropy indices is affected by image distortions that arise from residual eddy currents produced by the diffusion-sensitizing gradients. Correc...

journal_title：Magnetic resonance in medicine

authors： Bodammer N,Kaufmann J,Kanowski M,Tempelmann C

更新日期：2004-01-01 00:00:00

abstract：:Rapid MR imaging using the stimulated echo acquisition mode (STEAM) technique yields single-shot images without any sensitivity to resonance offset effects. However, the absence of susceptibility-induced signal voids or geometric distortions is at the expense of a somewhat lower signal-to-noise ratio than EPI. As a co...

journal_title：Magnetic resonance in medicine

authors： Block KT,Frahm J

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:To verify MR measurements of myocardial extracellular volume fraction (ECV) based on clinically applicable T1-mapping sequences against ECV measurements by radioisotope tracer in pigs and to relate the results to those obtained in volunteers. METHODS:Between May 2016 and March 2017, 8 volunteers (25 ± 4 years,...

journal_title：Magnetic resonance in medicine

authors： Nordlund D,Xanthis C,Bidhult S,Jablonowski R,Kanski M,Kopic S,Carlsson M,Engblom H,Aletras AH,Arheden H

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To investigate the uncertainties on relative Cramér-Rao lower bound (rCRB) estimates and demonstrate their biasing effects in MRS quantification. THEORY AND METHODS:Simulations were performed to calculate the distribution of the computed rCRB (noted rCRB*) for several rCRB levels. One hundred thousand simulati...

journal_title：Magnetic resonance in medicine

authors： Bonny JM,Pagès G

更新日期：2019-02-01 00:00:00

abstract：:A novel method, called relaxo-oximetry, for rapid spatially resolved in vivo measurements of oxygen concentration using time-domain radiofrequency (RF) electron paramagnetic resonance (EPR) is described. Time-domain data from triaryl methyl (TAM)-based single-electron contrast agents were processed by systematic delet...

journal_title：Magnetic resonance in medicine

authors： Subramanian S,Yamada K,Irie A,Murugesan R,Cook JA,Devasahayam N,Van Dam GM,Mitchell JB,Krishna MC

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:Image-guided prostate biopsies are routinely acquired in the diagnosis and treatment monitoring of prostate cancer, yielding useful tissue for identifying metabolic biomarkers and therapeutic targets. We developed an optimized biopsy tissue culture protocol in combination with [1,6-13 C2 ]glucose labeling and q...

journal_title：Magnetic resonance in medicine

authors： Bancroft Brown J,Sriram R,VanCriekinge M,Delos Santos R,Sun J,Delos Santos J,Tabatabai ZL,Shinohara K,Nguyen H,Peehl DM,Kurhanewicz J

更新日期：2019-08-01 00:00:00

abstract：:SENSitivity Encoding (SENSE) greatly enhances the quality of diffusion-weighted echo-planar imaging (EPI) by reducing blurring and off-resonance artifacts. Such improvement would also be desirable for diffusion tensor imaging (DTI), but measures derived from the diffusion tensor can be extremely sensitive to any kind ...

journal_title：Magnetic resonance in medicine

authors： Bammer R,Auer M,Keeling SL,Augustin M,Stables LA,Prokesch RW,Stollberger R,Moseley ME,Fazekas F

更新日期：2002-07-01 00:00:00

abstract：:MR techniques have proven their ability to investigate skeletal muscle function in situ. Their benefit in terms of noninvasiveness is, however, lost in animal research, given that muscle stimulation and force output measurements are usually achieved using invasive surgical procedures, thereby excluding repeated invest...

journal_title：Magnetic resonance in medicine

authors： Giannesini B,Vilmen C,Le Fur Y,Dalmasso C,Cozzone PJ,Bendahan D

更新日期：2010-07-01 00:00:00

abstract：:Stimulated-echo localized spectroscopy was combined with phase- and frequency-encoding gradients to obtain "zoom" or magnified images of specific organs in situ. The technique requires neither surface coils nor an imaging coil arrangement that exclusively isolates the target organ. This technique can be readily applie...

journal_title：Magnetic resonance in medicine

authors： Mills P,Chew W,Litt L,Moseley M

更新日期：1987-10-01 00:00:00

abstract：PURPOSE:Currently, the time required for image reconstruction is prohibitively long if data are acquired using multidimensional imaging trajectories that make use of multichannel systems equipped with nonlinear gradients. Methods are presented that reduce the computational complexity of the iterative time-domain recons...

journal_title：Magnetic resonance in medicine

authors： Schultz G,Gallichan D,Reisert M,Hennig J,Zaitsev M

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:To demonstrate the feasibility of imaging a bolus of co-polarized [1-13 C]pyruvate and 13 C-urea to simultaneously assess both metabolism and perfusion in the rodent heart. METHODS:Copolarized [1-13 C]pyruvate and 13 C-urea was imaged using a multi-echo, flow-sensitized spiral pulse sequence. Healthy rats were...

journal_title：Magnetic resonance in medicine

authors： Lau AZ,Miller JJ,Robson MD,Tyler DJ

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:Reference region models (RRMs) can quantify tumor perfusion in dynamic contrast-enhanced MRI without an arterial input function. Inspection of the RRM reveals that one of the free parameters in the fit is uniquely linked to the reference region and is common to all voxels. A two-step approach is proposed that t...

journal_title：Magnetic resonance in medicine

authors： Ahmed Z,Levesque IR

更新日期：2017-10-01 00:00:00

abstract：:Rapid flow imaging was achieved with a partial field of view (pFOV) spiral motion-encoded technique. The FOV and the acquisition time were reduced by a factor of 2 by undersampling k-space. The pFOV spiral k-space trajectory aliased signals from outside a circular ring whose radius was inversely proportional to the di...

journal_title：Magnetic resonance in medicine

authors： Nezafat R,Thompson RB,Derbyshire JA,McVeigh ER

更新日期：2006-09-01 00:00:00

abstract：:Accurate quantification of myocardial perfusion remains challenging due to saturation of the arterial input function at high contrast concentrations. A method for estimating the arterial input function directly from tissue curves in the myocardium that avoids these difficulties is presented. In this constrained altern...

journal_title：Magnetic resonance in medicine

authors： Fluckiger JU,Schabel MC,DiBella EV

更新日期：2011-08-01 00:00:00

abstract：:The rotationally invariant trace/3 apparent diffusion coefficients (ADC) of N-acetyl aspartate (NAA), creatine and phosphocreatine (tCr), and choline (Cho) were determined using a diffusion-weighted stimulated echo acquisition mode sequence at 3 T in three separate human brain regions, namely the subcortical white mat...

journal_title：Magnetic resonance in medicine

authors： Ellegood J,Hanstock CC,Beaulieu C

更新日期：2005-05-01 00:00:00

abstract：:When deoxygenated, blood behaves as an effective susceptibility contrast agent. Changes in brain oxygenation can be monitored using gradient-echo echo-planar imaging. With this technique, difference images also demonstrate that blood oxygenation is increased during periods of recovery from respiratory challenge. ...

journal_title：Magnetic resonance in medicine

authors： Turner R,Le Bihan D,Moonen CT,Despres D,Frank J

更新日期：1991-11-01 00:00:00

abstract：:An automatic fMRI protocol for the investigation of the human auditory cortex has been developed. For the activation of the auditory system, the scanner noise itself is the source of sound. Rapid switching of B0 gradients allows the generation of tones of defined frequencies and amplitude on a conventional scanner wit...

journal_title：Magnetic resonance in medicine

authors： Bilecen D,Radü EW,Scheffler K

更新日期：1998-12-01 00:00:00

abstract：PURPOSE:Diabetic nephropathy (DN) is the leading cause of renal failure; however, current clinical tests are insufficient for assessing this disease. DN is associated with changes in renal metabolites, so we evaluated the utility of chemical exchange saturation transfer (CEST) imaging to detect changes characteristic o...

journal_title：Magnetic resonance in medicine

authors： Wang F,Kopylov D,Zu Z,Takahashi K,Wang S,Quarles CC,Gore JC,Harris RC,Takahashi T

更新日期：2016-11-01 00:00:00

abstract：:The dependence of 1/T1 on the magnetic field strength (the relaxation dispersion) has been measured at 37 degrees C on autopsy samples of human brain gray and white matter at field strengths corresponding to proton Larmor frequencies between 10 kHz and 50 MHz (0.0002-1.2 T). Additional measurements of 1/T1 and 1/T2 ha...

journal_title：Magnetic resonance in medicine

authors： Fischer HW,Rinck PA,Van Haverbeke Y,Muller RN

更新日期：1990-11-01 00:00:00

abstract：:A new method is presented for the quantitative determination of regional blood volumes in vivo. It is based on rapid quantitative T1 mapping by Snapshot FLASH MRI combined with the injection of an intravascular MR contrast agent. Regional blood volumes in four different tissues of the rat (skeletal muscle, heart, live...

journal_title：Magnetic resonance in medicine

authors： Schwarzbauer C,Syha J,Haase A

更新日期：1993-05-01 00:00:00

abstract：:The fate of the 13C label arising from [U-13C]succinate in rabbit renal proximal convoluted tubular (PCT) cells, incubated with [U-13C]succinate, was investigated by 13C NMR spectroscopy of the perchloric acid extracts of the cell pellets. The 13C label of [U-13C]succinate was predominantly metabolized into glutamate,...

journal_title：Magnetic resonance in medicine

authors： Jans AW,Willem R

更新日期：1990-04-01 00:00:00

abstract：:The purpose of this study was to demonstrate the feasibility of dynamic oxygen-enhanced MRI in a clinical setting. We hypothesized that dynamic oxygen enhancement can reflect the regional diffusing capacity of the lung. Ten patients with pulmonary emphysema and seven healthy volunteers were examined with a respiratory...

journal_title：Magnetic resonance in medicine

authors： Ohno Y,Hatabu H,Takenaka D,Van Cauteren M,Fujii M,Sugimura K

更新日期：2002-06-01 00:00:00

abstract：:High-signal artifacts produced by cerebrospinal fluid (CSF) flow can adversely affect fluid-attenuated inversion recovery (FLAIR) imaging of the brain and spinal cord. This study explores the use of a nonslice-selective inversion pulse to eliminate CSF flow artifacts together with a technique called "K-space Reordered...

journal_title：Magnetic resonance in medicine

authors： Herlihy AH,Oatridge A,Curati WL,Puri BK,Bydder GM,Hajnal JV

更新日期：2001-08-01 00:00:00