Increase of estrogen receptor level by thyroxine in estrogen dependent pituitary tumor (MtT/F84) in rats.

Abstract:

:A rat transplantable pituitary tumor, MtT/F84, grows much faster in E2 treated rats than in normal females, but is much retarded in thyroidectomized rats. Triiodothyronine (T3) administration in a drinking water increased the tumor growth by the dose dependent manner. The tumor contained both estrogen receptor (ER) and T3 receptor. ER levels both in the nuclei and cytosols elevated 2 to 3 times by the T3 administration compared to those of control. E2 administration promotes the growth of MtT/F84 through elevation of nuclear ER level. T3 may directly elevate cellular ER level and thus it may enhance estrogenic actions including the tumor growth.

authors

Fujimoto N,Roy B,Watanabe H,Ito A

doi

10.1016/s0006-291x(88)80677-6

subject

Has Abstract

pub_date

1988-04-15 00:00:00

pages

44-8

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(88)80677-6

journal_volume

152

pub_type

杂志文章
  • Identification of 'molten globule'-like state in all beta-sheet protein.

    abstract::The cardiotoxin analogue III (CTX III), isolated from the Taiwan Cobra venom (Naja naja atra), is a sixty amino acid, all beta-sheet protein. The 2,2,2-trifluoro ethanol (TFE) induced unfolding of CTX III is studied under acidic conditions (pH 2.5). Using circular dichroism, 1-anilino-8-napthalene sulphonic acid bindi...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1995.1221

    authors: Kumar TK,Jayaraman G,Lee CS,Sivaraman T,Lin WY,Yu C

    更新日期:1995-02-15 00:00:00

  • Involvement of the G-protein-coupled receptor 4 in RANKL expression by osteoblasts in an acidic environment.

    abstract::Osteoclast activity is enhanced in acidic environments following systemic or local inflammation. However, the regulatory mechanism of receptor activator of NF-κB ligand (RANKL) expression in osteoblasts under acidic conditions is not fully understood. In the present paper, we detected the mRNA expression of the G-prot...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2015.01.142

    authors: Okito A,Nakahama K,Akiyama M,Ono T,Morita I

    更新日期:2015-03-06 00:00:00

  • ATP release into ADPKD cysts via pannexin-1/P2X7 channels decreases ENaC activity.

    abstract::Genetic predisposition is necessary for polycystic kidney disease (PKD) initiation, although there are other, incompletely identified downstream processes that are required for cyst growth. Their characterization may provide a unique opportunity for clinical interventions. One of the poorly studied phenomena in PKD is...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2019.03.177

    authors: Arkhipov SN,Pavlov TS

    更新日期:2019-05-21 00:00:00

  • Crystal structure of the sweet-tasting protein thaumatin II at 1.27Å.

    abstract::Thaumatin, an intensely sweet-tasting protein, elicits a sweet taste sensation at 50 nM. Here the X-ray crystallographic structure of one of its variants, thaumatin II, was determined at a resolution of 1.27 Å. Overall structure of thaumatin II is similar to thaumatin I, but a slight shift of the Cα atom of G96 in tha...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2011.05.158

    authors: Masuda T,Ohta K,Tani F,Mikami B,Kitabatake N

    更新日期:2011-07-08 00:00:00

  • Diversity within the JMJD2 histone demethylase family.

    abstract::JMJD2A-D belong to the JmjC domain-containing family of histone demethylases. JMJD2D is the most structurally divergent JMJD2 protein as it lacks the PHD and Tudor domains present in JMJD2A-C. Here, we systematically analyzed the histone demethylase specificity of JMJD2 proteins in vivo. We found that JMJD2A and C dem...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2006.12.147

    authors: Shin S,Janknecht R

    更新日期:2007-02-23 00:00:00

  • Peroxiredoxin 1 is involved in disassembly of flagella and cilia.

    abstract::Cilia/flagella are evolutionarily conserved cellular organelles. In this study, we demonstrated that Dunaliella salina Peroxiredoxin 1 (DsPrdx1) localized to the flagella and basal bodies, and was involved in flagellar disassembly. The link between DsPrdx1 and flagella of Dunaliella salina (D. salina) encouraged us to...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2014.01.081

    authors: Gong F,Liu H,Li J,Xue L,Zhang M

    更新日期:2014-02-14 00:00:00

  • Thyroid hormones upregulate apolipoprotein E gene expression in astrocytes.

    abstract::Apolipoprotein E (apoE), a protein mainly involved in lipid metabolism, is associated with several neurodegenerative disorders including Alzheimer's disease. Despite numerous attempts to elucidate apoE gene regulation in the brain, the exact mechanism is still uncovered. The mechanism of apoE gene regulation in the br...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2015.10.132

    authors: Roman C,Fuior EV,Trusca VG,Kardassis D,Simionescu M,Gafencu AV

    更新日期:2015-12-04 00:00:00

  • Heterochromatin protein 1γ overexpression in P19 embryonal carcinoma cells elicits spontaneous differentiation into the three germ layers.

    abstract::P19 embryonal carcinoma (EC) cells are pluripotent stem cells and have numerous morphological and biochemical properties in common with embryonic stem (ES) cells. However, P19 cells differentiate very ineffectively as embryoid bodies (EBs) without the specific chemical inducers whereas ES cells exhibit spontaneous dif...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2012.12.128

    authors: Morikawa K,Ikeda N,Hisatome I,Shirayoshi Y

    更新日期:2013-02-08 00:00:00

  • Expression of 5-oxoETE receptor in prostate cancer cells: critical role in survival.

    abstract::Previously, we reported that metabolism of arachidonic acid through the 5-lipoxygenase (5-LOX) pathway plays an important role in the survival and growth of human prostate cancer cells. Inhibition of 5-LOX by pharmacological inhibitors triggers apoptosis in prostate cancer cells within hours of treatment, which is pre...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2005.10.189

    authors: Sundaram S,Ghosh J

    更新日期:2006-01-06 00:00:00

  • The mitochondrial fatty acid synthesis (mtFASII) pathway is capable of mediating nuclear-mitochondrial cross talk through the PPAR system of transcriptional activation.

    abstract::Mammalian cells contain two fatty acid synthesis pathways, the cytosolic FASI pathway, and the mitochondrial FASII pathway. The selection behind the conservation of the mitochondrial pathway is not completely understood, given the presence of the cytosolic FAS pathway. In this study, we show through heterologous gene ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2013.10.072

    authors: Parl A,Mitchell SL,Clay HB,Reiss S,Li Z,Murdock DG

    更新日期:2013-11-15 00:00:00

  • Effects of metal ions on the binding activity of the human leukocyte leukotriene B4 receptor.

    abstract::The specific binding of leukotriene B4 to its receptor on human leukocyte membranes was enhanced in a dose-dependent manner by metal ions. Mg2+ and Ca2+ were the most potent followed by Mn2+ and Co2+. These divalent cations increased receptor density and did not affect the binding affinity. Addition of the same divale...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1997.6953

    authors: Ng CF,Haeggström JZ,Samuelsson B

    更新日期:1997-07-18 00:00:00

  • The carbohydrate structures of Trypanosoma brucei brucei MITat 1.6 variant surface glycoprotein. A re-investigation of the C-terminal glycan.

    abstract::We have studied the oligosaccharide chains of the variant surface glycoprotein (VSG) of Trypanosoma brucei brucei MITat 1.6. Glycopeptides were generated by Pronase digestion, purified by gel permeation and ion-exchange chromatography, and structurally characterized by 1H and 31P NMR spectroscopy in combination with c...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1993.2412

    authors: Strang AM,Allen AK,Holder AA,van Halbeek H

    更新日期:1993-11-15 00:00:00

  • Purification of the yellow fluorescent protein from Vibrio fischeri and identity of the flavin chromophore.

    abstract::A low molecular weight protein (approximately 25,000 D) exhibiting a yellow fluorescence emission peaking at approximately 540 nm was isolated from Vibrio fischeri (strain Y-1) and purified to apparent homogeneity. FMN is the chromophore, but it exhibits marked red shifts in both the absorption (lambda max = 380, 460 ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(87)90696-6

    authors: Macheroux P,Schmidt KU,Steinerstauch P,Ghisla S,Colepicolo P,Buntic R,Hastings JW

    更新日期:1987-07-15 00:00:00

  • Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptor.

    abstract::Most G protein-coupled receptors (GPCRs) are N-glycosylated proteins but the role of this post-translational modification in GPCR biosynthesis has not been extensively studied. We previously showed that the non-glycosylated AT(1) receptor is inefficiently expressed at the cell surface. In this study, we addressed whet...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2005.12.016

    authors: Lanctôt PM,Leclerc PC,Escher E,Guillemette G,Leduc R

    更新日期:2006-02-10 00:00:00

  • FSH-receptor isoforms and FSH-dependent gene transcription in human monocytes and osteoclasts.

    abstract::Cells of the monocyte series respond to follicle stimulating hormone (FSH) by poorly characterized mechanisms. We studied FSH-receptors (FSH-R) and FSH response in nontransformed human monocytes and in osteoclasts differentiated from these cells. Western blot and PCR confirmed FSH-R expression on monocytes or osteocla...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2010.02.112

    authors: Robinson LJ,Tourkova I,Wang Y,Sharrow AC,Landau MS,Yaroslavskiy BB,Sun L,Zaidi M,Blair HC

    更新日期:2010-03-26 00:00:00

  • Association of membrane-associated guanylate kinase-interacting protein-1 with Raf-1.

    abstract::Membrane-associated guanylate kinase-interacting protein (MAGUIN)-1 was identified as a protein interacting with synaptic scaffolding molecule (S-SCAM) and postsynaptic density (PSD)-95/synapse-associated protein (SAP)90. MAGUIN-1 has a chimerical molecular structure composed of one sterile alpha motif, one PSD-95/Dlg...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.2000.2475

    authors: Yao I,Ohtsuka T,Kawabe H,Matsuura Y,Takai Y,Hata Y

    更新日期:2000-04-13 00:00:00

  • Cleavage of carcinoembryonic antigen induces metastatic potential in colorectal carcinoma.

    abstract::Carcinoembryonic antigen (CEA), a widely used tumor marker, is attached by a glycosylphosphatidylinositol (GPI) anchor motif to the cell membrane. Recent study suggested that membrane-bound CEA might be cleaved by glycosylphosphatidylinositol-phospholipase D (GPI-PLD). We studied the effect of GPI-PLD on the cleavage ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2005.05.084

    authors: Yamamoto Y,Hirakawa E,Mori S,Hamada Y,Kawaguchi N,Matsuura N

    更新日期:2005-07-22 00:00:00

  • Selectin GMP-140 (CD62; PADGEM) binds to sialosyl-Le(a) and sialosyl-Le(x), and sulfated glycans modulate this binding.

    abstract::GMP-140 (CD62; PADGEM) is a member of the selectin family expressed highly at the surface of platelets and endothelial cells by agonists such as thrombin or phorbol esters. Previous studies indicate that the lectin domain of GMP-140 recognizes sialosyl-Le(x) (SLex) and to a lesser extent Le(x) (Polley MJ, et al., Proc...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(91)92069-v

    authors: Handa K,Nudelman ED,Stroud MR,Shiozawa T,Hakomori S

    更新日期:1991-12-31 00:00:00

  • High-active truncated luciferase of copepod Metridia longa.

    abstract::The technology of real-time imaging in living cells is crucial for understanding of intracellular events. For this purpose, bioluminescent reporters have been introduced as sensitive and convenient tools. Metridia luciferase (MLuc) from the copepod Metridia longa is a coelenterazine-dependent luciferase containing a n...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2011.11.063

    authors: Markova SV,Burakova LP,Vysotski ES

    更新日期:2012-01-06 00:00:00

  • Arachidonic acid and related methyl ester mediate protein kinase C activation in intact platelets through the arachidonate metabolism pathways.

    abstract::Unlike unsaturated fatty acids, which almost fully activated purified brain protein kinase C in a phosphatidylserine- and Ca2(+)-free reaction, related methyl esters were poorly active in vitro. In contrast, methyl arachidonate was revealed to be as potent as arachidonic acid in activating protein kinase C in intact p...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(90)91983-y

    authors: Fan XT,Huang XP,Da Silva C,Castagna M

    更新日期:1990-06-29 00:00:00

  • Achieving selectivity between highly homologous tyrosine kinases: a novel selective erbB2 inhibitor.

    abstract::The discovery of small molecule kinase inhibitors for use as drugs is a promising approach for the treatment of cancer and other diseases, but the discovery of highly specific agents is challenging because over 850 kinases are expressed in mammalian cells. Systematic modification of the 4-anilino functionality of a se...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/s0006-291x(03)01160-4

    authors: Bhattacharya SK,Cox ED,Kath JC,Mathiowetz AM,Morris J,Moyer JD,Pustilnik LR,Rafidi K,Richter DT,Su C,Wessel MD

    更新日期:2003-07-25 00:00:00

  • A 1H NMR study of the solution conformation of the neuropeptide galanin.

    abstract::The conformations of the neuropeptide galanin in water and trifluoroethanol solutions have been examined by 1H NMR spectroscopy. Analysis of two-dimensional NMR experiments enabled the assignment of virtually all the 1H resonances of galanin in trifluoroethanol solution and many of the 1H resonances in aqueous solutio...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(90)90980-2

    authors: Wennerberg AB,Cooke RM,Carlquist M,Rigler R,Campbell ID

    更新日期:1990-02-14 00:00:00

  • ATP promotes NCX-reversal in aortic smooth muscle cells by DAG-activated Na+ entry.

    abstract::Reversal of the plasma membrane Na(+)/Ca(2+) exchanger (NCX) has been shown to mediate Ca(2+) influx in response to activation of G-protein linked receptors. Functional coupling of reverse-mode NCX with canonical transient receptor potential channels (TRPC), specifically TRPC6, has recently been demonstrated by our la...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2007.04.080

    authors: Syyong HT,Poburko D,Fameli N,van Breemen C

    更新日期:2007-06-15 00:00:00

  • Kinetic studies of the electron exchange reaction between the octaheme cytochrome c3 (Mr 26000) and the hydrogenase from Desulfovibrio desulfuricans Norway.

    abstract::The octaheme cytochrome c3 (Mr 26000) from Desulfovibrio desulfuricans Norway was studied using cyclic voltammetry at the pyrolytic graphite electrode. The kinetics of reduction of the octaheme cytochrome c3 (Mr 26000) from D. desulfuricans Norway by the Ni-Fe-Se hydrogenase purified from the same organism was investi...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(91)91414-8

    authors: Haladjian J,Bianco P,Guerlesquin F,Bruschi M

    更新日期:1991-08-30 00:00:00

  • Interleukin-1 beta induces cytosolic phospholipase A2 gene in rats C6 glioma cell line.

    abstract::Treatment of the rat C6 glioma cell line with interleukin-1 beta (IL-1 beta) resulted in an accumulation of cytosolic phospholipase A2 (cPLA2) in mRNA level. The increase of cPLA2 in mRNA level was observed at 6 hours after treatment of IL-1 beta and reached to the maximal level at 12 hours. The accumulation also rema...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1994.2622

    authors: Ozaki M,Morii H,Qvist R,Watanabe Y

    更新日期:1994-11-30 00:00:00

  • Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model.

    abstract::Rhabdomyosarcomas (RMS) represent the most common childhood soft-tissue sarcoma. Over the past few decades outcomes for low and intermediate risk RMS patients have slowly improved while patients with metastatic or relapsed RMS still face a grim prognosis. New chemotherapeutic agents or combinations of chemotherapies h...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2013.05.001

    authors: Kaylani SZ,Xu J,Srivastava RK,Kopelovich L,Pressey JG,Athar M

    更新日期:2013-06-14 00:00:00

  • Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae.

    abstract::Autophagy is the bulk degradation of cytosolic materials in lysosomes/vacuoles of eukaryotic cells. In the yeast Saccharomyces cerevisiae, 17 Atg proteins are known to be involved in autophagosome formation. Genome wide analyses have shown that Atg17 interacts with numerous proteins. Further studies on these interacti...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2007.02.150

    authors: Kabeya Y,Kawamata T,Suzuki K,Ohsumi Y

    更新日期:2007-05-04 00:00:00

  • Integrated information as a possible basis for plant consciousness.

    abstract::It is commonly assumed that plants do not possess consciousness. Since the criterion for this assumption is usually human consciousness this assumption represents a top down attitude. It is obvious that plants are not animals and using animal criteria of consciousness will lead to its rejection in plants. However usin...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2020.10.022

    authors: Calvo P,Baluška F,Trewavas A

    更新日期:2020-10-17 00:00:00

  • Insulin-dependent phosphatidylinositol 3'-kinase activity co-precipitates with insulin receptor in human circulating mononuclear cells.

    abstract::In order to establish a working cellular model for the study of post-receptor signaling events, insulin-dependent phosphatidylinositol 3' (PtdIns 3')-kinase activity was investigated in circulating mononuclear cells from normal subjects. The p85 alpha regulatory subunit of PtdIns 3'-kinase co-precipitated with activat...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1995.1494

    authors: Renard E,Grigorescu F,Lavabre C,Kahn CR

    更新日期:1995-04-06 00:00:00

  • Involvement of superoxide radical in signal transduction regulating stomatal movements.

    abstract::Stomatal movements are regulated by alternate phase transition in the lipophilic domains of membrane initiated by blue light through activation of plasmalemma redox system. ABA blocks the blue light activated redox reactions leading to the accumulation of superoxide (O2.-) radical inducing melting of the membrane and ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1994.2625

    authors: Purohit S,Kumar GP,Laloraya M,Laloraya MM

    更新日期:1994-11-30 00:00:00