Abstract:
:In this paper we report the synthesis of four fluorinated analogues of brassinosteroids in which fluorine was introduced stereoselectively at C-2. The bioactivity of these new compounds was evaluated using the rice lamina inclination test. The results show that two of these analogues elicit high bioactivity, suggesting the involvement of hydrogen bond interactions between the active brassinosteroids and their cellular receptor.
journal_name
Steroidsjournal_title
Steroidsauthors
Acebedo SL,Ramírez JA,Galagovsky LRdoi
10.1016/j.steroids.2008.12.006subject
Has Abstractpub_date
2009-04-01 00:00:00pages
435-40issue
4-5eissn
0039-128Xissn
1878-5867pii
S0039-128X(08)00329-2journal_volume
74pub_type
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