Kinetics of hydrothermal crystallization under saturated steam pressure and the self-healing effect by nanocrystallite for hydroxyapatite coatings.

abstract：:To date, there has been little investigation of biodegradable tissue engineered arterial grafts (TEAG) using clinically relevant large animal models. The purpose of this study is to explore how pore size of electrospun scaffolds can be used to balance neoarterial tissue formation with graft structural integrity under ...

journal_title：Acta biomaterialia

authors： Matsuzaki Y,Iwaki R,Reinhardt JW,Chang YC,Miyamoto S,Kelly J,Zbinden J,Blum K,Mirhaidari G,Ulziibayar A,Shoji T,Breuer CK,Shinoka T

更新日期：2020-10-01 00:00:00

abstract：:For next-generation regenerative medicine and cancer therapy applications, the development of multifunctional biodegradable biomaterials with good antibacterial activity, biocompatibility and gene delivery capability is showing increased interests. As a natural cationic polypeptide, poly(ε-l-lysine) (EPL) has been as ...

journal_title：Acta biomaterialia

authors： Zhou L,Xi Y,Yu M,Wang M,Guo Y,Li P,Ma PX,Lei B

更新日期：2017-08-01 00:00:00

abstract：:Tilapia fish-scale type I atelocollagen hydrogels with aligned fibril structures were fabricated under a strong magnetic field of 6 or 12 T using two different methods. In the first method, a solution of acid-soluble collagen was neutralized with phosphate buffer saline and maintained in the magnetic field at 28°C for...

journal_title：Acta biomaterialia

authors： Chen S,Hirota N,Okuda M,Takeguchi M,Kobayashi H,Hanagata N,Ikoma T

更新日期：2011-02-01 00:00:00

abstract：:A dual targeting delivery system was developed to completely conquer the two barriers that glioma treatment faces: the blood-brain barrier (BBB) and the brain-glioma barrier. Recently, a system comprising AS1411 aptamer (for glioma targeting) and TGN peptide (for BBB targeting) modified nanoparticles (AsTNPs) was deve...

journal_title：Acta biomaterialia

authors： Gao H,Yang Z,Zhang S,Pang Z,Liu Q,Jiang X

更新日期：2014-02-01 00:00:00

abstract：:In the present report, a degradable gene delivery system (PAMS/DNA/10NLS) containing nucleus location signal peptide (NLS) was prepared. The agarose gel electrophoresis, particle size and zeta potential of PAMS/DNA/10NLS were similar to those of PAMS/DNA, which proved that NLS did not affect the interaction between PA...

journal_title：Acta biomaterialia

authors： Chen K,Guo L,Zhang J,Chen Q,Wang K,Li C,Li W,Qiao M,Zhao X,Hu H,Chen D

更新日期：2017-01-15 00:00:00

abstract：:After skin tissue injury or pathological removal, vascularization timing is paramount in graft survival. As full thickness skin grafts often fail to become perfused over larger surfaces, split-thickness grafts are preferred and can be used together with biomaterials, which themselves are non-angiogenic. One way of pro...

journal_title：Acta biomaterialia

authors： McLuckie M,Robotti F,Sanchez-Macedo N,Enderlin D,Frese L,Cheng PF,Levesque MP,Egaña JT,Poulikakos D,Ferrari A,Lindenblatt N

更新日期：2020-04-01 00:00:00

abstract：:In the U.S., 30% of adults suffer joint pain, most commonly in the knee, which severely limits mobility and is often attributed to injury of cartilage and underlying bone in the joint. Current treatment methods such as microfracture result in less resilient fibrocartilage with eventual failure; autografting can cause ...

journal_title：Acta biomaterialia

authors： Gupte MJ,Swanson WB,Hu J,Jin X,Ma H,Zhang Z,Liu Z,Feng K,Feng G,Xiao G,Hatch N,Mishina Y,Ma PX

更新日期：2018-12-01 00:00:00

abstract：:Dental-derived mesenchymal stem cells (MSCs) are promising candidates for cartilage regeneration, with a high capacity for chondrogenic differentiation. This property helps make dental MSCs an advantageous therapeutic option compared to current treatment modalities. The MSC delivery vehicle is the principal determinan...

journal_title：Acta biomaterialia

authors： Moshaverinia A,Xu X,Chen C,Akiyama K,Snead ML,Shi S

更新日期：2013-12-01 00:00:00

abstract：:The easy clinical handling and applicability of biomaterials has become a focus of materials research due to rapidly increasing time and cost pressures in the public health sector. The present study assesses the in vitro and in vivo performance of a flexible, mouldable, cottonwool-like nanocomposite based on poly(lact...

journal_title：Acta biomaterialia

authors： Schneider OD,Weber F,Brunner TJ,Loher S,Ehrbar M,Schmidlin PR,Stark WJ

更新日期：2009-06-01 00:00:00

abstract：:Multiple myeloma is a malignant disease characterized by accumulation of clonal plasma cells in the bone marrow. Uncoupling of bone formation and resorption by myeloma cells leads to osteolytic lesions. These are prone to fracture and represent a possible survival space for myeloma cells under treatment causing diseas...

journal_title：Acta biomaterialia

authors： Grab AL,Seckinger A,Horn P,Hose D,Cavalcanti-Adam EA

更新日期：2019-09-15 00:00:00

abstract：:Diabetics are prone to chronic wounds that have slower healing, and methods of accelerating the wound closure and to ensure protection from infections are critically needed. MicroRNA-146a gets dysregulated in diabetic wounds and injection of this microRNA combined with reactive oxygen species-scavenging cerium oxide n...

journal_title：Acta biomaterialia

authors： Sener G,Hilton SA,Osmond MJ,Zgheib C,Newsom JP,Dewberry L,Singh S,Sakthivel TS,Seal S,Liechty KW,Krebs MD

更新日期：2020-01-01 00:00:00

abstract：:The Mg-Ca alloy system has been proposed as a potential new kind of degradable biomaterial with possible application within bone. Here microarc oxidation (MAO) coatings were fabricated on top of a Mg-Ca alloy using different applied voltages and the effect of applied voltage on the surface morphology and phase constit...

journal_title：Acta biomaterialia

authors： Gu XN,Li N,Zhou WR,Zheng YF,Zhao X,Cai QZ,Ruan L

更新日期：2011-04-01 00:00:00

abstract：:Periodontal diseases like periodontitis and peri-implantitis have been linked with Gram-negative anaerobes. The incorporation of various chemotherapeutic agents, including metal ions, into several materials and devices has been extensively studied against periodontal bacteria, and materials doped with metal ions have ...

journal_title：Acta biomaterialia

authors： Goudouri OM,Kontonasaki E,Lohbauer U,Boccaccini AR

更新日期：2014-08-01 00:00:00

abstract：:Load-bearing tissues owe their mechanical strength to their highly anisotropic collagenous structure. To date attempts to engineer mechanically strong connective tissue have failed, mainly due to a lack of ability to reproduce the native collagen organization in constructs synthesized by cultured cells in vitro. The a...

journal_title：Acta biomaterialia

authors： Saeidi N,Sander EA,Zareian R,Ruberti JW

更新日期：2011-06-01 00:00:00

abstract：:This study deals with cytotoxicity assays performed on an array of commercially manufactured inorganic nanoparticulate materials, including Ag, TiO(2), Fe(2)O(3), Al(2)O(3), ZrO(2), Si(3)N(4), naturally occurring mineral chrysotile asbestos and carbonaceous nanoparticulate materials such as multiwall carbon nanotube a...

journal_title：Acta biomaterialia

authors： Soto K,Garza KM,Murr LE

更新日期：2007-05-01 00:00:00

abstract：:Using novel nitric oxide (NO)-generating polymeric hydrogels that can be rapidly photopolymerized in situ, we can deliver NO locally at the site of vascular injury. Depending on material design, these poly(ethylene glycol) (PEG)-based hydrogels can generate NO for up to 50 d. This study demonstrates the ability of nit...

journal_title：Acta biomaterialia

authors： Lipke EA,West JL

更新日期：2005-11-01 00:00:00

abstract：:Bioactive ions released from bioceramics play important roles in bone regeneration; however, it is unclear how each ionic composition in complex bioceramics exerts its specific effect on bone regeneration. The aim of this study is to elucidate the functional effects of Sr and Si ions in bioceramics on the regeneration...

journal_title：Acta biomaterialia

authors： Mao L,Xia L,Chang J,Liu J,Jiang L,Wu C,Fang B

更新日期：2017-10-01 00:00:00

abstract：:Topography at the nanoscale can lead to dramatic changes in the adhesion of cells to surfaces and their subsequent viability. For biological applications, including tissue engineering and cell-based sensing, the large internal surface area of ordered mesoporous carbons provides an opportunity for enhanced sensitivity ...

journal_title：Acta biomaterialia

authors： Chavez VL,Song L,Barua S,Li X,Wu Q,Zhao D,Rege K,Vogt BD

更新日期：2010-08-01 00:00:00

abstract：:The pericellular matrix (PCM) is a narrow tissue region that surrounds chondrocytes in articular cartilage. Previous parametric studies of cell-matrix interactions suggest that the mechanical properties of the PCM relative to those of the extracellular matrix (ECM) can significantly affect the micromechanical environm...

journal_title：Acta biomaterialia

authors： Alexopoulos LG,Setton LA,Guilak F

更新日期：2005-05-01 00:00:00

abstract：:Tissue-derived extracellular matrix (ECM) biomaterials to regenerate the meniscus have gained increasing attention in treating meniscus injuries and diseases, particularly for aged persons and athletes. However, ECM scaffold has poor cell infiltration and can only be implanted using surgical procedures. To overcome th...

journal_title：Acta biomaterialia

authors： Wu J,Ding Q,Dutta A,Wang Y,Huang YH,Weng H,Tang L,Hong Y

更新日期：2015-04-01 00:00:00

abstract：:Biocompatible and elastic porous tubular structures based on poly(1,3-trimethylene carbonate), PTMC, were developed as scaffolds for tissue engineering of small-diameter blood vessels. High-molecular-weight PTMC (M(n) = 4.37 x 10(5)) was cross-linked by gamma-irradiation in an inert nitrogen atmosphere. The resulting ...

journal_title：Acta biomaterialia

authors： Song Y,Kamphuis MM,Zhang Z,Sterk LM,Vermes I,Poot AA,Feijen J,Grijpma DW

更新日期：2010-04-01 00:00:00

abstract：:The geometric features of bone graft substitutes, such as the pore and pore interconnection sizes, are of paramount importance for their biological performance. Such features are generally characterized by micro-computed tomography (μCT). Unfortunately, the resolution of μCT is often too limited. The aim of this study...

journal_title：Acta biomaterialia

authors： Bashoor-Zadeh M,Baroud G,Bohner M

更新日期：2011-11-01 00:00:00

abstract：:Polylactide (PLA) polymers containing five distinct lengths of fluorinated (from C3F7 to C13F27) and non-fluorinated (C6H13) end-groups were successfully synthesized by ring-opening polymerization of d,l-lactide. Fluorination was expected to increase the encapsulation efficiency of perfluorohexane (PFH). 150 nm nanoca...

journal_title：Acta biomaterialia

authors： Picheth G,Houvenagel S,Dejean C,Couture O,Alves de Freitas R,Moine L,Tsapis N

更新日期：2017-12-01 00:00:00

abstract：UNLABELLED:A new a biocompatible Ti42Zr40Ta3Si15 (atomic %) porous bulk glassy alloy was produced by combination of rapid solidification and powder metallurgy techniques. Amorphous alloy ribbons were fabricated by melt spinning, i.e. extremely fast quenching the molten alloy with 10(6)K/s from T=1973K down to room temp...

journal_title：Acta biomaterialia

authors： Nicoara M,Raduta A,Parthiban R,Locovei C,Eckert J,Stoica M

更新日期：2016-05-01 00:00:00

abstract：:Several processing technologies and engineering strategies have been combined to create scaffolds with superior performance for efficient tissue regeneration. Cartilage tissue is a good example of that, presenting limited self-healing capacity together with a high elasticity and load-bearing properties. In this work, ...

journal_title：Acta biomaterialia

authors： Ribeiro VP,da Silva Morais A,Maia FR,Canadas RF,Costa JB,Oliveira AL,Oliveira JM,Reis RL

更新日期：2018-05-01 00:00:00

abstract：:The aim of this study was to fabricate a fibrous scaffold that closely resembled the micro-structural architecture and mechanical properties of collagen fibres found in the anterior cruciate ligament (ACL). To achieve this aim, fibrous scaffolds were made by electrospinning L-lactide based polymers. L-Lactide was chos...

journal_title：Acta biomaterialia

authors： Surrao DC,Waldman SD,Amsden BG

更新日期：2012-11-01 00:00:00

abstract：UNLABELLED:ECM-based materials are appealing for tissue engineering strategies because they may promote stem cell recruitment, cell infiltration, and cell differentiation without the need to supplement with additional biological factors. Cartilage ECM has recently shown potential to be chondroinductive, particularly in...

journal_title：Acta biomaterialia

authors： Beck EC,Barragan M,Tadros MH,Gehrke SH,Detamore MS

更新日期：2016-07-01 00:00:00

abstract：:Surgical and interventional therapies for atherosclerotic lesions of the infrainguinal arteries are notorious for high rates of failure. Frequently, this leads to expensive reinterventions, return of disabling symptoms or limb loss. Interaction between the artery and repair material likely plays an important role in r...

journal_title：Acta biomaterialia

authors： Kamenskiy AV,Pipinos II,Dzenis YA,Lomneth CS,Kazmi SA,Phillips NY,MacTaggart JN

更新日期：2014-03-01 00:00:00

abstract：:In vitro degradation and chondrocyte-encapsulation of chitosan hydrogel made of crosslinkable and water-soluble chitosan derivative (CML) at neutral pH and body temperature were studied with respect to weight loss, cytoviability, DNA content and cell morphology. In vitro degradation of the chitosan hydrogels was sensi...

journal_title：Acta biomaterialia

authors： Hong Y,Song H,Gong Y,Mao Z,Gao C,Shen J

更新日期：2007-01-01 00:00:00

abstract：:Titanium (Ti) has been widely used as an implant material due to the excellent biocompatibility and corrosion resistance of its oxide surface. Biomaterials must be sterile before implantation, but the effects of sterilization on their surface properties have been less well studied. The effects of cleaning and steriliz...

journal_title：Acta biomaterialia

authors： Park JH,Olivares-Navarrete R,Baier RE,Meyer AE,Tannenbaum R,Boyan BD,Schwartz Z

更新日期：2012-05-01 00:00:00