Abstract:
:Amlodipine is a calcium-channel antagonist with neuropharmacological properties believed to be protective against cerebral hypoperfusion, microinfarcts, and excitoxic cell death. Based on its pharmacological properties, we hypothesized that amlodipine would be associated with improved attention, processing speed, memory, and executive functioning at treatment follow-up in 84 cocaine-dependent individuals enrolled in a 12-week, placebo-controlled, double-blind clinical trial of amlodipine. We also hypothesized that better cognitive functioning at baseline would be associated with reduced cocaine use (negative urine drug screens) and longer treatment retention (last session attended). Results indicated that amlodipine produced no measurable benefit in cognitive functioning. Percent perseverative errors on Wisconsin Card Sorting Test was negatively correlated with treatment retention (n = 84, r = -.350, p < .01). No other findings were significant. Thus, cocaine-dependent individuals who repeated mistakes and benefited less from corrective feedback on a problem-solving task discontinued treatment earlier. Notably, no other cognitive measures predicted treatment outcome. The observed relationship implicates the relevance of executive functioning to treatment outcome for cocaine dependence.
journal_name
J Subst Abuse Treatjournal_title
Journal of substance abuse treatmentauthors
Turner TH,LaRowe S,Horner MD,Herron J,Malcolm Rdoi
10.1016/j.jsat.2009.03.009subject
Has Abstractpub_date
2009-12-01 00:00:00pages
328-34issue
4eissn
0740-5472issn
1873-6483pii
S0740-5472(09)00036-1journal_volume
37pub_type
杂志文章,随机对照试验abstract::The process of eliciting client language toward change (change talk [CT]) is implicated as a causal mechanism in motivational interviewing (MI) and brief motivational interventions (BMI). We investigated the articulation of counselor behaviors and CT during BMI with young men. We coded 149 sessions using the Motivatio...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2010.06.010
更新日期:2010-10-01 00:00:00
abstract::The association of physical and sexual abuse with substance abuse has frequently been noted among chemically dependent women. Without diagnosis and treatment of the trauma, female substance abusers are vulnerable to relapse and/or revictimization. This paper describes a model for education and preliminary treatment of...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/0740-5472(90)90003-9
更新日期:1990-01-01 00:00:00
abstract::Research has not consistently supported an association between stage of change and substance abuse treatment retention. This study examined whether social desirability response bias could help explain why. Participants (N = 200) recruited from an outpatient program completed the University of Rhode Island Change Asses...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2011.09.013
更新日期:2012-06-01 00:00:00
abstract::In the context of the COVID-19 pandemic and the state of emergency that the government of Spain declared, the rapid adaptation of health services is of paramount importance to preserve access to and continuity of service delivery. This research note underscores the importance of ensuring a sufficient quantity of metha...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2020.108154
更新日期:2020-12-01 00:00:00
abstract::A paper/pencil instrument, adapted from Miller and colleagues' (1991) Helpful Responses Questionnaire (HRQ), was developed to assess clinician skill with core communicative aspects involved in delivering contingency management (CM). The instrument presents a single vignette consisting of six points of client dialogue ...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jsat.2015.02.006
更新日期:2015-08-01 00:00:00
abstract::Attaining altered states of consciousness is described as a basic human motive. The substance dependent population is distinguished from other populations because they pursue these states destructively by inappropriate use of alcohol and drugs. Despite a body of literature supporting the benefits of altered states of ...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章,评审
doi:10.1016/0740-5472(91)90030-e
更新日期:1991-01-01 00:00:00
abstract::Sixty-nine cocaine-dependent outpatients were exposed to cocaine-related stimuli and to non-drug events on separate days. Cocaine cue sessions were always followed by a meeting with a trained clinician designed to eliminate any craving that remained following cue presentations. Urine samples were collected before each...
journal_title:Journal of substance abuse treatment
pub_type: 临床试验,杂志文章
doi:10.1016/s0740-5472(97)00290-0
更新日期:1998-09-01 00:00:00
abstract::Devising interventions to provide integrated treatment for addiction and medical problems is an urgent issue. This study piloted a structural intervention, Directly Administered Antiretroviral Therapy (DAART), to assist methadone-maintenance patients in HIV medication adherence. Twenty-four participants received: (1) ...
journal_title:Journal of substance abuse treatment
pub_type: 临床试验,杂志文章
doi:10.1016/j.jsat.2012.08.014
更新日期:2012-12-01 00:00:00
abstract::We determined the specialty, geographic location, practice type and treatment capacity of waivered clinicians in Washington State. We utilized the April 2011 Drug Enforcement Agency roster of all waivered buprenorphine prescribers and cross-referenced the data with information from the American Medical Association and...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2012.07.006
更新日期:2013-03-01 00:00:00
abstract::This article presents an empirically validated intervention, Brief Strategic Family Therapy (BSFT), for the treatment of adolescent drug abusers. The BSFT intervention steps and program format are presented. Challenges to implementation in community treatment settings are discussed to identify factors that may facilit...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章,评审
doi:10.1016/s0740-5472(02)00265-9
更新日期:2002-09-01 00:00:00
abstract::Despite aggressive efforts to recruit into treatment cocaine users 21 years and younger, we obtained only 12 such clients over a period of 9 months, while recruiting 122 adult cocaine clients during a comparable time frame. An examination of admissions data for the city, state, and nation indicated that our experience...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/0740-5472(89)90013-5
更新日期:1989-01-01 00:00:00
abstract::Treatments for cannabis dependence are associated with high rates of lapse/relapse, underscoring the importance of identifying malleable risk factors that are associated with quit failure. Whereas research has demonstrated that poor sleep quality following cannabis discontinuation is related to subsequent use, there h...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2012.08.224
更新日期:2013-04-01 00:00:00
abstract::Gratitude is a central component of addiction recovery for many, yet it has received scant attention in addiction research. In a sample of 67 individuals entering abstinence-based alcohol-use-disorder treatment, this study employed gratitude and abstinence variables from sequential assessments (baseline, 6months, 12mo...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2017.04.013
更新日期:2017-07-01 00:00:00
abstract::The purpose of this study was to evaluate the impact of opiate maintenance pharmacotherapy (OMP) on the biopsychosocial status of opiate-addicted patients in a cultural environment (France) that is not favorable to OMP and where methadone is not available. Buprenorphine and laudanum (opium tincture), which, to our kno...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/0740-5472(94)90008-6
更新日期:1994-11-01 00:00:00
abstract::Recognition of valuable natural resources suggests a need to accept a degree of responsibility to preserve and nurture the commodity, and to prevent its destruction. Health care professionals generally embrace such an ethic with reference to the environment, the quality of living for clients, and the need to assume pr...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/0740-5472(84)90032-1
更新日期:1984-01-01 00:00:00
abstract::Individuals in treatment for opioid dependence have smoking rates 3-5 times greater than the U.S. prevalence rate. Traditional smoking cessation strategies have been ineffective in this population. Novel approaches are needed as well as harm reduction avenues. E-cigarettes (e-cigs) may provide such a novel harm reduct...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2014.11.002
更新日期:2015-05-01 00:00:00
abstract::Medication-assisted treatment (MAT) with methadone or buprenorphine has been shown to be more effective at reducing the use of illicit opioids, the risk of drug-related overdose, and overall healthcare costs, on average, compared to abstinence-based addiction treatments for individuals with an opioid use disorder (OUD...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2019.05.015
更新日期:2019-09-01 00:00:00
abstract::Persons who abuse or are dependent on opioids are at elevated risk for arrest. Co-occurring behavioral health problems may exacerbate that risk, although the extent of any such increase has not been described. This study examines such risk factors among 40,238 individuals with a diagnosis of opioid abuse or dependence...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2014.05.002
更新日期:2014-09-01 00:00:00
abstract::An implementation approach, featuring direct, onsite technical assistance is described, and findings from a pilot study assessing the capability of Federally Qualified Health Centers to provide integrated behavioral health services are presented. Investigators used the Behavioral Health Integration in Medical Care (BH...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2015.08.006
更新日期:2016-01-01 00:00:00
abstract::This report describes the current approach to testing for the human immunodeficiency virus (HIV) antibody at Phoenix House, a large therapeutic community (TC) in the northeastern United States, and presents findings on retention of clients who have been tested for HIV antibodies and notified of their HIV serostatus. A...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/0740-5472(94)90102-3
更新日期:1994-09-01 00:00:00
abstract::We studied a modified therapeutic community designed for the treatment of patients with combined substance abuse and psychiatric disorders. This model has been ap117117plied on a limited basis in clinical practice, and little is known about the characteristics of patients who are likely to complete the prescribed stay...
journal_title:Journal of substance abuse treatment
pub_type: 临床试验,杂志文章
doi:10.1016/s0740-5472(97)00136-0
更新日期:1998-03-01 00:00:00
abstract::Patient views of the helpful aspects of treatment were examined in the NIDA Collaborative Cocaine Treatment Study, a multi-site trial comparing four psychosocial treatments: individual cognitive therapy (CT), individual supportive expressive dynamic therapy (SE), individual drug counseling, and group drug counseling o...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jsat.2004.06.007
更新日期:2004-09-01 00:00:00
abstract::We examine the prevalence of screening for student alcohol misuse/abuse among 333 U.S. colleges via a survey of campus leaders. We also use latent class modeling to identify classes of colleges based on screening practices. We found that most colleges conduct screening after a student is involved in an alcohol-related...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2012.01.001
更新日期:2012-10-01 00:00:00
abstract::This article examines variables that predicted outpatient treatment entry within 6 months of residential detoxification. Patient data were collected from 632 injection drug users enrolled in a randomized trial conducted at eight detoxification programs within the National Drug Abuse Treatment Clinical Trials Network (...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2009.12.012
更新日期:2010-06-01 00:00:00
abstract::Opioid treatment programs (OTPs) operate within a rigid set of clinical guidelines and regulations that specify the number of required OTP visits for supervised administration of methadone. To ensure physical distancing in light of COVID-19, the federal government loosened regulations to allow for additional flexibili...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2020.108219
更新日期:2021-03-01 00:00:00
abstract::The purpose of this study was to examine the evidence of psychotherapeutic integrated treatment (IT) programs for individuals with concurrent substance use disorders and trauma histories. Electronic searches of Cochrane Central Register of Controlled Trials, MEDLINE, Web of knowledge, PubMed, PsycINFO, CINAHL, PILOTS,...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jsat.2011.09.001
更新日期:2012-01-01 00:00:00
abstract::For many individuals, substance use leads to a chronic cycle of relapse, treatment reentry, and recovery, often lasting for decades. This study replicates earlier work, documents the transition patterns within the cycle during a 3-year period, and identifies variables that predict these transitions. Data are from 1,32...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2004.09.006
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:Women with substance use disorders enter treatment with limited personal network resources and reduced recovery support. This study examined the impact of personal networks on substance use by 12 months post treatment intake. METHODS:Data were collected from 284 women who received substance abuse treatmen...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2015.11.002
更新日期:2016-03-01 00:00:00
abstract::We explored patient, therapist, and program variability in the alliance in relation to drug and alcohol use during treatment, and whether alliance mediates the relation of program characteristics to drug/alcohol use. Data (N = 1,613 patients) were drawn from a randomized clinical trial investigating the efficacy of an...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2011.01.003
更新日期:2011-06-01 00:00:00
abstract::The Washington Circle (a multiple-disciplinary group of providers, researchers, managed care representatives, and public policy representatives) examined three performance measures for alcohol and other drug (AOD) services. These measures, which were developed and applied to managed care organizations' administrative ...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/s0740-5472(02)00303-3
更新日期:2002-12-01 00:00:00