Abstract:
:Devising interventions to provide integrated treatment for addiction and medical problems is an urgent issue. This study piloted a structural intervention, Directly Administered Antiretroviral Therapy (DAART), to assist methadone-maintenance patients in HIV medication adherence. Twenty-four participants received: (1) antiretroviral medications at the methadone clinic daily before receiving their methadone; (2) take-home antiretroviral medication for days they were not scheduled to attend the methadone clinic, and (3) brief adherence counseling to address adherence barriers. DAART lasted 24 weeks, with a planned step-down to twice-weekly administration in weeks 25-36, followed by self-administration in weeks 37-48. Retention rates at weeks 24, 36, and 48 were 83, 92, and 75% respectively. DAART was associated with improvement in the proportion of participants achieving viral suppression as well as with high medication adherence rates (clinic-verified; 85% and self-reported 97%) during the active intervention phase. DAART was effective as an intervention but did not promote transition to self-administration. This study demonstrates that DAART is adaptable and simple enough to be implemented into methadone treatment programs interested in providing HIV adherence services.
journal_name
J Subst Abuse Treatjournal_title
Journal of substance abuse treatmentauthors
Sorensen JL,Haug NA,Larios S,Gruber VA,Tulsky J,Powelson E,Logan DP,Shapiro Bdoi
10.1016/j.jsat.2012.08.014subject
Has Abstractpub_date
2012-12-01 00:00:00pages
418-23issue
4eissn
0740-5472issn
1873-6483pii
S0740-5472(12)00149-3journal_volume
43pub_type
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