Abstract：
:The purpose of this study was to evaluate the impact of opiate maintenance pharmacotherapy (OMP) on the biopsychosocial status of opiate-addicted patients in a cultural environment (France) that is not favorable to OMP and where methadone is not available. Buprenorphine and laudanum (opium tincture), which, to our knowledge, has not been reported previously in the scientific literature for OMP, were used in this study of a group of 18 opioid-dependent subjects. At time of initiation of OMP, mean age was 33 years, sex ratio male: female was 14:4, average duration of drug use was 11.2 years. Six patients received laudanum p.o., 15 g daily; 12 patients received buprenorphine sublingual 2 to 4 mg daily. This group of patients was selected because of persistent relapse and impairment after an average of 5.7 drug-free-oriented treatments over a period of 6.8 years. Initial evaluation and follow-up were made by way of a 150-min semi-structured interview using the Lifetime Retrospective Evaluation Score Table (LREST) and the Addiction Severity Index (ASI). Results showed that body weight and scores for physical and psychological health, socioprofessional status, and family relationships improved significantly after 14 months of OMP. These results show that highly impaired opiate-addicted patients doing poorly in drug-free treatment can respond to OMP even though methadone is not available and the idea of OMP is not favored.
journal_name
J Subst Abuse Treatjournal_title
Journal of substance abuse treatmentauthors
Auriacombe M,Grabot D,Daulouède JP,Vergnolle JP,O'Brien C,Tignol Jdoi
10.1016/0740-5472(94)90008-6subject
Has Abstractpub_date
1994-11-01 00:00:00pages
565-8issue
6eissn
0740-5472issn
1873-6483journal_volume
11pub_type
杂志文章abstract：:Devising interventions to provide integrated treatment for addiction and medical problems is an urgent issue. This study piloted a structural intervention, Directly Administered Antiretroviral Therapy (DAART), to assist methadone-maintenance patients in HIV medication adherence. Twenty-four participants received: (1) ...
journal_title：Journal of substance abuse treatment
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abstract：:Many drug abusers have repeated exposure to treatment, yet little is known about the reasons some individuals re-enter treatment following relapse to drug use. This paper examines the predictors of treatment re-entry among cocaine abusers who relapsed to cocaine use (N = 347) within 5 years following their index treat...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,多中心研究
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journal_title：Journal of substance abuse treatment
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journal_title：Journal of substance abuse treatment
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abstract：:Hazardous alcohol consumption has been frequently reported among women with HIV infection and is associated with a variety of negative health consequences. Treatments to reduce alcohol use may bring in health benefits. However, little is known regarding the utilization of alcohol treatment services among HIV+ women wi...
journal_title：Journal of substance abuse treatment
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pub_type： 临床试验,杂志文章
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更新日期：1996-07-01 00:00:00
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,多中心研究
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更新日期：2011-12-01 00:00:00
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journal_title：Journal of substance abuse treatment
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2005.05.005
更新日期：2005-09-01 00:00:00
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
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journal_title：Journal of substance abuse treatment
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journal_title：Journal of substance abuse treatment
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1994-05-01 00:00:00
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2018.12.007
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pub_type： 杂志文章
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,多中心研究
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pub_type： 杂志文章,随机对照试验
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,评审
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更新日期：1989-01-01 00:00:00
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
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更新日期：2007-10-01 00:00:00
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
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journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
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更新日期：2012-06-01 00:00:00
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